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Auricularia polytricha and Flammulina velutipes ameliorate inflammation and modulate the gut microbiota via regulation of NF-κB and Keap1/Nrf2 signaling pathways on DSS-induced inflammatory bowel disease

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Food Bioscience 2022年第3期47卷 356-370页

作者： Ivan Stève Nguepi Tsopmejio Miao Ding jiali Wei Cong Zhao Yu jiang Yuting Li Hui song School of Life Science Jilin Agricultural UniversityJilinPR China Department of Animal Biology and Physiology University of Yaoundé ICameroon Engineering Research Center of Chinese Ministry of Education for Edible and Medicinal Fungi ChangchunPR China

Flammulina velutipes and Auricularia polytricha are two popular dietary mushrooms,especially in the Northeast of *** have revealed many pharmacological effects due to their bioactive compounds,but their possible mechanism of action involved in inflammation remains poorly ***,Inflammatory bowel disease(IBD)which is a chronic disease and progressive inflammation in the gastrointestinal tract were used to evaluate their anti-inflammatory and modulatory properties on the intestinal microbiota via the signaling pathways involved by oral administration of ***(FVE)and ***(APE).Mice were daily received 3%DSS in the drinking water followed by the daily administration of FVE and *** food consumption,weight variation and DAI score were assessed during the experiment and inflammatory parameters,mRNA and protein expressions to determine the possible signaling pathways involved,and the gut microbiota from the cecum by high-throughput *** showed that APE and FVE improved clinical symptoms,inflammatory cytokines and oxidative *** also attenuated the mRNA and proteins expressions in colon ***,APE and FVE regulated DSS-induced intestinal dysbiosis and stimulated the SCFAs ***,APE and FVE could improve DSS-induced IBD in mice suggesting that they represent novels therapeutic drugs and could be used as prebiotic to modulate the gut microbiota and preserve intestinal integrity.

关键词： Flammulina velutipes Auricularia polytricha Inflammatory bowel disease Signaling pathways Intestinal microbiota

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带有界不确定性的加权混合估计方法

武汉大学学报（信息科学版） 2020年第7期45卷 949-955页

作者：宋迎春宋采薇左廷英中南大学有色金属成矿预测与地质环境监测教育部重点实验室湖南长沙410083 有色资源与地质灾害探查湖南省重点实验室湖南长沙410083 中南大学地球科学与信息物理学院湖南长沙410083

大地测量中各种异方差多源观测模型进行融合都需要进行混合估计。由于附加信息和样本信息在估计过程中作用是不均等的,需要建立新的加权平差准则,平衡先验约束和观测信息对参数估计的影响。把多源观测数据看成是观测信息和一些随机约束... 详细信息

大地测量中各种异方差多源观测模型进行融合都需要进行混合估计。由于附加信息和样本信息在估计过程中作用是不均等的,需要建立新的加权平差准则,平衡先验约束和观测信息对参数估计的影响。把多源观测数据看成是观测信息和一些随机约束信息,首先利用椭球近似描述有界不确定信息,建立了基于外接椭球特征矩阵迹最小的平差准则,然后提出了一个新的观测信息融合方法,并给出了一种优化权的计算方法,使得加权混合估计方法能有效应用于大地测量数据处理,最后,通过算例验证了算法的有效性,说明了集员估计解与带权混合估计的关系。

关键词：随机约束有界不确定性加权混合估计集员估计信息融合

Damping Property of Supersaturated ZnA127Ce Alloy during Natural Aging

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journal of Materials Science & Technology 2001年第1期17卷 9-10页

作者： jingpei XIE Yaomin ZHU Yanpei song Xiaoying WANG and Quande CHEN Dept.of Material Engineering , Luoyang Institute of Technology, Luoyang 471039. China Dep. of Mater. Eng. Luoyang Inst. of Technol. Luoyang 471039 China

The microstructures and damping property of supersaturated ZnA127Ce alloy during natural aging have been investigated. H-800 TEM was mainly used to research the microstructures. The relationship between microstructure and damping property was primarily studied. The results showed that solution plus natural aging was the best heat treatment, which could improve the damping property. Both continuous precipitation and cellular reaction occurred during the aging. Continuous precipitation follows the sequence: β→spherical GP zones→elliptical GP zones→intermediate phase R→n. The cellular reaction can be written as follows:β→a+n+ε.

关键词： Ce Damping Property of Supersaturated ZnA127Ce Alloy during Natural Aging

A study on coupling technique and implementation of the wave-circulation coupled model

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High Technology Letters 2014年第1期20卷 82-87页

作者：张志远 Liu Li Zhou Yufeng Zhang Cheng Li Ruizhe Chen Yushu song Guojie Yang Guangwen Department of Computer Science and Technology Tsinghua University Ministry of Education Key Laboratory for Earth System Modeling Center for Earth System ScienceTsinghua University Hydro-Meteorological Center of Navy

The coupler is fundamental for a coupled model to realize complex interactions among component *** paper focuses on the coupling process of Wave-Circulation(W-C) coupled model which consists of MASNUM(key laboratory of marine science and numerical modeling wave model)and POM(Princeton Ocean Model).The current coupling module of this coupled model is based on the inefficient I/O file,which has already become a performance bottleneck especially when the coupled model utilizes a large number of *** improve the performance of the W-C model,a flexible coupling module based on the model coupling toolkit(MCT) is designed and implemented to replace the current I/O file coupling module in the coupled *** studies that we have carried out demonstrate that our online coupling module can dramatically improve the parallel performance of the coupled *** online coupling module outperforms the I/O file coupling *** processes increase to 96,the whole process of EXP-C takes only 695.8 seconds,which is only 58.8%of the execution time of *** on our experiments under 2D Parallel Decomposition(2DPD),we suggest setting parallel decomposition strategies automatically to component models in order to achieve high parallel efficiency.

关键词： coupling technique model coupling toolkit (MCT) W-C coupled online cou-pling module 2D Parallel Decomposition (2DPD) parallel performance

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逆载对管道内汽水两相流临界热流密度的影响

北京航空航天大学学报 2017年第4期43卷 842-848页

作者：宋军辉宋保银张钊李冈南京航空航天大学航空宇航学院南京210016

利用旋转平台对逆载作用下矩形通道内汽水两相流临界换热进行了实验研究。通过改变逆载大小、入口流体过冷度、流体质量流速等参数,获得了静止和逆载作用2种状态下矩形管道内汽水两相流临界换热实验数据。实验结果表明,质量流速随着加... 详细信息

利用旋转平台对逆载作用下矩形通道内汽水两相流临界换热进行了实验研究。通过改变逆载大小、入口流体过冷度、流体质量流速等参数,获得了静止和逆载作用2种状态下矩形管道内汽水两相流临界换热实验数据。实验结果表明,质量流速随着加热时间的增长而减小,进出口压差则反之;临界状态下,质量流速随着逆载、过冷度的增大而减小;进出口压差随着逆载、质量流速的增大而增大,随着过冷度的增大而减小;临界热流密度值随着逆载、质量流速、入口过冷度的增大而增大;其中逆载对临界热流密度的影响最为显著,在逆载从0g^2.5g变换范围内,临界热流密度可提高50%。

关键词：矩形管道两相流临界热流密度逆载实验研究

A state-of-the-art review on passivation and biofouling of Ti and its alloys in marine environments

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journal of Materials Science & Technology 2018年第3期34卷 421-435页

作者： Shaokun Yan Guang-Ling song Zhengxian Li Haonan Wang Dajiang Zheng Fuyong Cao Miroslava Horynova Matthew S.Dargusch Lian Z-hou Center for Marine Materials Corrosion&Protection State Key Laboratory of Physical Chemistry of Solid SurfacesCollege of MaterialsXiamen University422 S.Siming Rd.Xiamen 361005China Corrosion&Protection Research Lab Northwest Institute for Non-ferrous Metal ResearchXi'an 710016China Centre for Advanced Materials Processing and Manufacturing(AMPAM) School of Mechanical and Mining EngineeringThe University of QueenslandBrisbaneQld 4072Australia Nanjing Tech University Nanjing 211800China

High strength-to-weight ratio, commendable biocompatibility and excellent corrosion resistance make Ti alloys widely applicable in aerospace, medical and marine industries. However, these alloys suffer from serious biofouling, and may become vulnerable to corrosion attack under some extreme marine conditions. The passivating and biofouling performance of Ti alloys can be attributed to their compact, stable and protective films. This paper comprehensively reviews the passivating and biofouling behavior, as well as their mechanisms, for typical Ti alloys in various marine environments. This review aims to help extend applications of Ti alloys in extremely harsh marine conditions.

关键词： Ti alloy Passivity Biofouling

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微型扑翼绕流的N-S方程数值模拟

西北工业大学学报 2008年第1期26卷 104-109页

作者：谢辉宋文萍宋笔锋西北工业大学翼型叶栅空气动力学国防科技重点实验室陕西西安710072

基于广义无限插值理论生成了适用于模拟微型扑翼粘性绕流的三维C-O型网格,应用有限体积法结合双时间推进技术求解了微型扑翼在低速、低雷诺数下的粘性绕流。控制方程采用预处理后的三维可压缩非定常N-S方程组,有效地克服了低速流动条件... 详细信息

基于广义无限插值理论生成了适用于模拟微型扑翼粘性绕流的三维C-O型网格,应用有限体积法结合双时间推进技术求解了微型扑翼在低速、低雷诺数下的粘性绕流。控制方程采用预处理后的三维可压缩非定常N-S方程组,有效地克服了低速流动条件下求解常规可压缩N-S方程遇到的刚性问题。通过与参考文献结果的比较验证了文中方法的正确性,并研究了扑翼相关参数对其气动特性的影响。文中所得到结论对扑翼的气动设计具有指导意义。

关键词：扑翼动网格非定常预处理方法 N—S方程

High-throughput investigations of configurational-transformation-dominated serrations in CuZr/Cu nanolaminates

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journal of Materials Science & Technology 2020年第18期52卷 192-199页

作者： William Yi Wang Bin Gana Deye Lin jun Wang Yiguang Wang Bin Tang Hongchao Kou Shunli Shang Yi Wang Xingyu Gao Haifeng song Xidong Hui Laszlo j.Kecskes Zhenhai Xia Karin A.Dahmen Peter K.Liaw jinshan Lia Zi-Kui Liu State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi'an.710072China Beijing Key Laboratory of Advanced High Temperature Materials Central Iron and Steel Research InstituteBeijing100081China IMDEA Materials Institute Calle Eric Kandel 2GetafeMadrid28906Spain CAEP Software Center for High Performance Numerical Simulation Institute of Applied Physics and Computational MathematicsBeijing100088China Department of Materials Science and Engineering The Pennsylvania State UniversityUniversity ParkPA16802USA State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing100083China Hopkins Extreme Materials Institute Johns Hopkins UniversityBaltimoreMD21218USA Department of Physics University of Illinois at Urbana ChampaignUrbanaIL61801USA Department of Materials Science and Engineering The University of TennesseeKnoxvilleTN37996USA

Metallic amorphous/crystalline(A/C)nanolaminates exhibit excellent ductility while retaining their high ***,the underlying physical mechanisms and the resultant structural changes during plastic deformation still remain *** the present work,the structure-property relationship of CuZr/Cu A/C nanolaminates is established through integrated high-throughput micro-compression tests and molecular dynamics simulations together with high-resolution transmission electron *** serrated flow of nanolaminates results from the formation of hexagonal-close-packed(HCP)-type stacking faults and twins inside the face-centered-cubic(FCC)Cu nano-grains,the body-centered-cubic(BCC)-type ordering at their grain boundaries,and the crystallization of the amorphous CuZr *** serration behavior of CuZr/Cu A/C nanolaminates is determined by several factors,including the formation of dense dislocation networks from the multiplication of initial dislocations that formed after yielding,weak-spots-related configurational-transitions and shear-transition-zone activities,and deformation-induced *** present work provides an insight into the heterogeneous deformation mechanism of A/C nanolaminates at the atomic scale,and mechanistic base for the microstructural design of self-toughening metallic-glass(MG)-based composites and A/C nanolaminates.

关键词： Nanolaminates Serration Configurational transformation Molecular dynamics Metallic glass

Study on As-Cast Structure of DC Casting Aluminum Alloy Under Dual Frequency Electromagnetic Field

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journal of Iron and Steel Research International 2012年第S1期19卷 265-268页

作者： ZHAO Zhi-hao WANG Gao-song CUI jian-zhong Key Lab.of EPM Ministry of EducationChinaNortheastern University

The as-cast structures of semi-continuous casting aluminum alloy under dual-frequency electromagnetic field were experimental *** results showed that the electromagnetic fields with different frequency have different function for improving the cast structure of aluminum alloy *** medium frequency electromagnetic field can change the surface morphology of melt pool in the casting process,increase the height of melt meniscus,improve the ingot's surface quality,and reduce the thickness of surface *** low frequency electromagnetic field is most obvious to as-cast structure improvement effect because of its high permeability in conductance *** low-frequency electromagnetic field can change flow pattern and temperature field in the melt,strengthen the heat transfer and mass transfer in the melt,decrease the depth of the sttmp and reduce the temperature ***,the as-cast structures are greatly refined,which can lead to the fine equiaxed as-cast structures throughout the cross-section of the ingot.

关键词： dual frequency electromagnetic field semi-continuous casting aluminum alloy as-cast structure