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1996 International Conference on Communication Technology

作者： j.shirlaw M.Saha j.Lake D.Robson Marconi Space Abbey WorksTitchfieldFarehamPO 14 4QAEngland

＜正＞In recent years,the demand for satellite communications systems has evolved to include personal mobile services and the provision of fixed services to rural *** on from central involvement in all generations of INMARSAT’s mobile communications space segment,Marconi Space has been developing advanced payload concepts for geostationary satellites to provide regional *** retain the heritage gained from the novel payload architecture designed and successfully delivered by Marconi Space for the INMARSAT 3 *** paper starts with the top level payload requirements for an example regional system and develops these into a generic payload architecture. The key technology issues are identified,and solutions provided,based on the extensive Marconi Space experience acquired through development of mobile payloads and internal development *** comparisons are made with the issues associated with the proposed global constellation systems.

关键词： Payloads Satellite communication Space technology Mobile communication Artificial satellites Space vehicles

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外阴阴道牙龈综合征:一种具特征性临床表现并新发现与HLAII-DQB1*0201等位基因关联的扁平苔藓严重亚型

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世界核心医学期刊文摘（皮肤病学分册） 2006年第9期2卷 57-57页

作者： Setterfield j.F Neill S shirlaw P.j. 周少娜

Background: The vulvovaginal gingival syndrome is an uncommon and severe variant of lichen planus characterized by erosions or desquamation of vulval, vaginal, and gingival mucosae with a predilection for scarring and stricture formation. Objective: We sought to define the clinical, immunopathologic, and human leukocyte antigen findings in a large cohort of patients. Methods: The clinical presentation and outcome during long-term follow-up were documented in 40 patients. In addition, human leukocyte antigen typing for class II by polymerase chain reaction and sequence-specific primers was performed. Results: During a mean follow-up period of 8.7 (SD ± 6.8) years, long-term sequelae included strictures of the esophagus, lachrymal ducts, and external auditory canal; loss of vulval architecture; vaginal stenosis; and buccal mucosal fibrosis. The DQB1 0201 allele was present in 80% of patients versus 41.8% of control subjects (P ≤ .0042; relative risk 3.71). Conclusion: Early diagnosis of this distinct subgroup of lichen planus, combined with appropriate therapeutic measures, may help to minimize the significant physical and psychologic morbidity associated with this scarring disorder.

关键词：等位基因关联外阴阴道临床表现扁平苔藓综合征牙龈亚型人类白细胞抗原

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