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Mathematical modelling of ball and plate system with experimental and correlation function-based model validation

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Control Theory and Technology 2024年第2期22卷 326-341页

作者： T.R.Dil kumar S.j.Mija Department of Electrical Engineering National Institute of Technology CalicutKozhikode673601KeralaIndia

The ball and plate system is an inherently nonlinear under actuated benchmark system used for validating the performance of various control schemes. A mathematical model depicting the dynamics close to that of the system is very much required for such a test bed. In this correspondence, the complete nonlinear model, a simplified nonlinear model, and a linearized model of the ball and plate system are developed. The system comprises a ball and plate mechanism and a rotary servo unit. The ball and plate mechanism is modelled using the Euler–Lagrange method, whereas the rotary servo subsystem is modelled from the first principles. The nonlinear model of the combined system is developed by including the dynamics of the servo motor with gear and rolling resistance between the ball and the plate. The simplified nonlinear model of the system is obtained with suitable assumptions. The model is linearized around the operating point using the jacobian. The validity of the developed models is investigated through correlation function analysis. The open-loop response of the three models, viz., nonlinear, simplified nonlinear, and linearized models, is analyzed in the MATLAB/Simulink platform. Since the open-loop system is unstable, the experimental validation of the model is performed with a double-loop PSO (particle swarm optimization) PID control scheme.

关键词： Ball and plate system Correlation function Model validation Particle swarm optimization(PSO) PSO PID controller

Study of Type-B QPOs Observed in Black Hole X-Ray Binary Swift j1728.9-3613

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Research in Astronomy and Astrophysics 2024年第3期24卷 1-9页

作者： Raj kumar Astrophysical Sciences Division Bhabha Atomic Research CentreMumbai 400085India Homi Bhabha National Institute Mumbai 400094India

We report the detection of type-B quasi-periodic oscillation(QPO)of the black hole X-ray binary Swift j1728.9-3613 observed by NICER during the 2019 outburst.A type-B QPO was observed for the first two days and it disappeared as flux increased,but again appeared at∼7.70 Hz when flux was dramatically *** source was found in the soft intermediate state during these *** further studied the energy dependence of the *** found that QPO was observed only for a higher energy range implying that the origin of QPO is possibly due to the corona emitting higher energy photons by the inverse Compton *** variation of spectral parameters can be explained with the disk truncation *** fractional rms was found to be monotonically increased with *** phase lag spectrum followed the“U-shaped”*** rms and phase lag spectrum are modeled and explained with the single-component Comptonization model vkompthdk.

关键词： X-rays binaries-accretion-accretion disks-X-rays individual (Swift j1728.9-3613)

Highly Efficient Back‑End‑of‑Line Compatible Flexible Si‑Based Optical Memristive Crossbar Array for Edge Neuromorphic Physiological Signal Processing and Bionic Machine Vision

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Nano-Micro Letters 2024年第11期16卷 323-339页

作者： Dayanand kumar Hanrui Li Dhananjay D.Kumbhar Manoj kumar Rajbhar Uttam kumar Das Abdul Momin Syed Georgian Melinte Nazek El‑Atab Smart Advanced Memory Devices and Applications(SAMA)LaboratoryElectrical and Computer EngineeringComputer Electrical Mathematical Science and EngineeringKing Abdullah University of Science and Technology(KAUST)23955‑6900 ThuwalSaudi Arabia

The emergence of the Internet-of-Things is anticipated to create a vast market for what are known as smart edge devices,opening numerous opportunities across countless domains,including personalized healthcare and advanced *** 3D integration,edge devices can achieve unprecedented miniaturization while simultaneously boosting processing power and minimizing energy ***,we demonstrate a back-end-of-line compatible optoelectronic synapse with a transfer learning method on health care applications,including electroencephalogram(EEG)-based seizure prediction,electromyography(EMG)-based gesture recognition,and electrocardiogram(ECG)-based arrhythmia *** experiments on three biomedical datasets,we observe the classification accuracy improvement for the pretrained model with 2.93%on EEG,4.90%on ECG,and 7.92%on EMG,*** optical programming property of the device enables an ultralow power(2.8×10^(-13) j)fine-tuning process and offers solutions for patient-specific issues in edge computing ***,the device exhibits impressive light-sensitive characteristics that enable a range of light-triggered synaptic functions,making it promising for neuromorphic vision *** display the benefits of these intricate synaptic properties,a 5×5 optoelectronic synapse array is developed,effectively simulating human visual perception and memory *** proposed flexible optoelectronic synapse holds immense potential for advancing the fields of neuromorphic physiological signal processing and artificial visual systems in wearable applications.

关键词： Neuromorphic computing Electrophysiological signal Artificial vision system Image recognition Memristor

Optimized protoplast isolation and transfection with a breakpoint:accelerating Cas9/sgRNA cleavage efficiency validation in monocot and dicot

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aBIOTECH 2024年第2期5卷 151-168页

作者： Debasmita Panda Subhasis Karmakar Manaswini Dash Swagat kumar Tripathy Priya Das Sagar Banerjee Yiping Qi Sanghamitra Samantaray Pradipta kumar Mohapatra Mirza j.Baig Kutubuddin A.Molla ICAR National Rice Research Institute CuttackOdisha 753006India Department of Botany Ravenshaw UniversityCuttackOdisha 753003India Department of Plant Science and Landscape Architecture University of MarylandCollege ParkMD 20742USA

The CRISPR-Cas genome editing tools are revolutionizing agriculture and basic biology with their simplicity and precision ability to modify target genomic ***-predicted guide RNAs(gRNAs)often fail to induce efficient cleavage at target *** target loci are inaccessible due to complex chromatin ***,there is no suitable tool available to predict the architecture of genomic target sites and their ***,significant time and resources are spent on performing editing experiments with inefficient *** in vitro-cleavage assay could provide a rough assessment of gRNA efficiency,it largely excludes the interference of native genomic *** in-vivo testing gives a proper assessment of the cleavage ability of editing reagents in a native genomic ***,we developed a modified protocol that offers highly efficient protoplast isolation from rice,Arabidopsis,and chickpea,using a sucrose gradient,transfection using PEG(polyethylene glycol),and validation of single guide RNAs(sgRNAs)cleavage efficiency of *** have optimized various parameters for PEG-mediated protoplast transfection and achieved high transfection efficiency using our protocol in both monocots and *** introduced plasmid vectors containing Cas9 and sgRNAs targeting genes in rice,Arabidopsis,and chickpea *** dual sgRNAs,our CRISPRdeletion strategy offers straightforward detection of genome editing success by simple agarose gel *** sequencing of PCR products confirmed the editing efficiency of specific ***,we demonstrated that isolated protoplasts can be stored for up to 24/48 h with little loss of viability,allowing a pause between isolation and *** high-efficiency protocol for protoplast isolation and transfection enables rapid(less than 7 days)validation of sgRNA cleavage efficiency before proceeding with stable *** isolation and transfection method can als

关键词： Protoplast Genome editing Transgene-free edited plants Rice Chickpea

Laparoscopic management of remnant gall bladder with stones: Lessons from a tertiary care centre's experience

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第1期7卷 27-33页

作者： Gilbert Samuel jebakumar jeevanandham Muthiah Loganathan jayapal R.Santhosh kumar Siddhesh Tasgaonkar K.S.Santhosh Anand j.K.A.jameel Sudeepta kumar Swain K.j.Raghunath Prasanna kumar Reddy Tirupporur Govindaswamy Balachandar Department of Surgical Gastroenterology Apollo HospitalsChennai 600006India Department of General Surgery Apollo HospitalsChennai 600006India Department of Minimal Access Surgery Apollo HospitalsChennai 600006India

Objective:Laparoscopic cholecystectomy is currently the gold standard for treating symptomatic gallstone *** its success,approximately 10%of patients may experience persistent biliary symptoms,leading to the post-cholecystectomy syndrome.A remnant gallbladder with cystic duct or bile duct stones is one of the causes of this *** objective of this study was to shed light on the clinical manifestations,evaluation,therapeutic strategies,and outcomes associated with laparoscopic management of symptomatic remnant ***:This was a retrospective study,conducted over a five-year period(january 2017 to December 2022)at Apollo Hospitals in South *** patients who underwent laparoscopic completion cholecystectomy for a remnant gall bladder were *** following data were collected:patient demographics,symptoms,preoperative investigations,intraoperative details and post operative ***:In total,36 patients were included and *** majority of patients were male(25,69.4%),with a mean age of 50.7±12.1 *** most common presentation was pain in the upper abdomen or right upper quadrant region(24,66.7%).The laparoscopic approach was attempted in all patients,with a success rate of 94.4%.Two patients required conversion to open *** fistula to the colon was observed in one *** was observed in 7 patients(19.4%),and stone clearance was successfully achieved using endoscopic retrograde cholangiopancreatography in all patients ***:Incomplete gall bladder removal either intentionally or unintentionally leaves a remnant gall bladder that is at risk for stone formation and *** who have this clinical entity with symptoms require a redo or complete cholecystectomy,a complex procedure associated with certain *** study highlights the feasibility and safety of laparoscopic completion cholecystectomy for the management of remnant gallbladder

关键词： Remnant gall bladder Stump cholecystitis Subtotal cholecystectomy Laparoscopic completion cholecystectomy

Structural,morphological,optical and antibacterial performances of rare earth(Sm)-doped ZnO nanorods

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journal of Rare Earths 2024年第11期42卷 2119-2127页

作者： A.Ravi j.Samuel S.Sahaya jude Dhas S.Usharani Turibius Simon D.Senthil kumar S.K.jasmin Vijitha A.Sivakumar Raju Suresh kumar C.S.Biju Department of Physics University College of Engineering Department of Physics and Research Centre Malankara Catholic College Manonmaniam Sundaranar University Saveetha School of Engineering Saveetha Institute of Medical and Technical SciencesSaveetha University Department of Chemistry S.I.V.E.T College Department of Biotechnology Vivekanandha College of Arts and Science for Woman (Autonomous) Department of Physics Vel Tech Rangarajan Dr.Sagunthala R & D Institute of Science and Technology Department of Physics & Research Centre Muslim Arts College Key Laboratory of High-temperature and High-pressure Study of the Earth's Interior Institute of GeochemistryChinese Academy of Sciences Department of Chemistry College of ScienceKing Saud University Department of Physics St. Alphonsa College of Arts and Science

The significant rise of ultra-violet（UV） radiation and pathogenic infectious bacteria poses a serious threat to global *** researchers' interests are attracted by novel materials with strong UVblocking ability,antibacterial activity and low toxicity to other *** this case,a simple wet chemical method with different annealing temperatures（400,500,and 600℃） was employed to create highly effective rare earth（Sm）-doped ZnO ***（101） plane of wurtzite ZnO shifts towards a lower angle with increasing annealing temperature,according to the X-ray diffraction（XRD） study findings,which additionally establishes the consequence of lattice *** of doublet peaks of Sm 3d(Sm 3d5/2and Sm 3d3/2) in the X-ray photoelectron spectroscopy（XPS） spectrum clearly validates the substitution of Sm3+ions in the 500℃-annealed *** 500℃-annealed nanorods exhibit combined performances of the wide band gap,improved UV absorbance,and vivid green luminescent emission（563 nm）.Additio nally,the nanorods have favorable UV-blocking execution of 96% for UVA at 360 nm,92% for UVB at 320 nm,and 57% for UVC at 225 nm,which is greater than the majority of ZnO-related materials that have been reported up to this *** doping is also appropriate for improving bacterial inhibition against the two studied strains（Escherichia coli and Staphylococcus aureus）,in addition to the intriguing features discussed ***,with maximum inhibition zone diameters of 20±0.72 and 18±0.57 mm,respectively,these nanorods exhibit high inhibitory action against *** and *** bacterial *** rare earth-doped material developed during the current experiment,which was annealed at 500℃,could potentially serve as an effective replacement for UV-blocking and antibacterial material,especially for biomedical applications.

关键词： Bacterial inhibition Metal oxide Rare earth doping UV-Shielding Wet chemical method

Development and validation of multicentre study on novel Artificial Intelligence-based Cardiovascular Risk Score(AICVD)

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Family Medicine and Community Health 2024年第S1期12卷 20-33页

作者： Shiv kumar jalepalli Prashant Gupta Andre L A j Dekker Inigo Bermejo Sujoy Kar Apollo Hospitals HyderabadTelanganaIndia Azure Microsoft Research IndiaBengaluruIndia Department of Radiation Oncology(Maastro) Maastricht UniversityMaastrichtNetherlands

Objective Cardiovascular diseases(CVD)are one of the most prevalent diseases in India amounting for nearly 30%of total deaths.A dearth of research on CVD risk scores in Indian population,limited performance of conventional risk scores and inability to reproduce the initial accuracies in randomised clinical trials has led to this study on large-scale patient *** objective is to develop an Artificial Intelligence-based Risk Score(AICVD)to predict CVD event(eg,acute myocardial infarction/acute coronary syndrome)in the next 10 years and compare the model with the Framingham Heart Risk Score(FHRS)and *** Our study included 31599 participants aged 18–91 years from 2009 to 2018 in six Apollo Hospitals in India.A multistep risk factors selection process using Spearman correlation coefficient and propensity score matching yielded 21 risk factors.A deep learning hazards model was built on risk factors to predict event occurrence(classification)and time to event(hazards model)using multilayered neural ***,the model was validated with independent retrospective cohorts of participants from India and the Netherlands and compared with FHRS and *** The deep learning hazards model had a good performance(area under the curve(AUC)0.853).Validation and comparative results showed AUCs between 0.84 and 0.92 with better positive likelihood ratio(AICVD−6.16 to FHRS−2.24 and QRisk3−1.16)and accuracy(AICVD−80.15%to FHRS 59.71%and QRisk351.57%).In the Netherlands cohort,AICVD also outperformed the Framingham Heart Risk Model(AUC−0.737 vs 0.707).Conclusions This study concludes that the novel AI-based CVD Risk Score has a higher predictive performance for cardiac events than conventional risk scores in Indian population.

关键词： AICVD Cardiovascular acute

A therapeutic potentiality and toxicity concern of nutrient plant Annona squamosa Linn.

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Traditional Medicine Research 2024年第3期9卷 52-65页

作者： Manisha Chandrakar Khomendra kumar Sarwa Vijendra kumar Suryawanshi kumari Pramila University College of Pharmacy Raipur Chhattisgarh Swami Vivekanand Technical University BhilaiChhattisgarh 492001India Department of Pharmacy Government Girls PolytechnicRaipurChhattisgarh 492001India Bharti College of Pharmacy Bharti UniversityDurgChhattisgarh 491001India Faculty of Pharmacy M J College BhilaiDurgChhattisgarh 490023India

Annona squamosa *** is famous for its nutritional value with a long history of medicinal benefits due to the presence of many phytochemicals,including alkaloids,diterpenes,essential oil,phytopeptides,*** studies envisaged that Annona squamosa possesses cytotoxic,diuretic,antiurolithiatic,antitumor,anti-psoriatic,antioxidant,and hepatoprotective *** plant is traditionally used for the treatment of wound infection,dysentery,seizure,tumors,fever,vomiting,parasitic infections,hypertension,thyroid,toothache,acne,heart disease,inflammation,diabetes,hair loss,dandruff,hemorrhage,maggot-infected sores,abortifacient,and ***,some chemical constituents isolated from the plant have shown specific toxic effects in human and animal models,such as acute oral toxic effects,genotoxic,neurotoxic,and ocular *** plant has diverse pharmacological actions,the seeds of this plant possess a genotoxic effect but on the contrary,the bark of the plant shows genoprotective activity.A large number of ethnobotanical studies reported the seed of this plant is used to induce abortion in humans,but a scientific study carried out in pregnant rats reported aqueous seed extract of the plant did not interfere with reproductive *** presented review summarized the traditional uses,pharmacological,and toxicological activities of the isolated compounds from this ***,some patents and commercial products related to Annona squamosa are also brought up in this article to explore its application which would attract the scientific community to search out its hidden side.

关键词： Annona squamosa cytotoxicity cancer abortifacient genotoxicity isosquamocin annonacin neurotoxicity ocular toxicity

Discussion on“Dispersion characteristics of clayey soils containing waste rubber particles”[j Rock Mech Geotech Eng 15(2023)3050e3058]

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journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3864-3865页

作者： Prithvendra Singh Devendra Narain Singh Pintu kumar Saw Department of Civil Engineering Indian Institute of Technology BombayMumbai400076India

We read with great interest the recent article by Erenson(2023)entitled“Dispersion characteristics of clayey soils containing waste rubber particles”.The author has studied the dispersion characteristics of clayey soils containing different percentages of waste rubber particles(WRPs)by performing several tests(*** limit,linear shrinkage limit,double hydrometer,crumb test and pinhole test)and scanning electron microscopy(SEM)analysis on five clayey(***-activated bentonite,refined ball clay,Ukrainian kaolin,Avanos kaolin and Afyon clay)samples containing 0%,5%,10%and 15%*** should be noted that Erenson(2023)has presented some interesting observations,but there are some serious issues that we want to share through this discussion and request the author of the original paper to address them to avoid their persistence in the scientific literature.

关键词： Waste rubber particles Dispersion characteristics Clay Bentonite Scientific literature Discussion