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Particuology 2015年第3期13卷 114-123页

作者： M.Domat F.E.Kruis N.L.Azong-Wara j.M.fernandez-Diaz Department of Physics University of OviedoC/Calvo Sotelos/nE-33007 OviedoSpain Institute of Technology for Nanostructures(NST) and Center for Nanointegration Duisburg-Essen(CENIDE) University of Duisburg-EssenBismarckstr.81D-47057 DuisburgGermany

The inversion of the particle size distribution from electrical mobility measurements is analyzed. Three different methods are adapted for a dot-matrix approach to the problem, especially for non-square or singular matrices, and applied to electrical mobility measurements from fixed or scanning voltages. Mul- tiply charged particles, diffusion losses, arbitrary voltage steps and noise were considered, which results in non-adjoining and overlapping transfer functions. The individual contribution of the transfer func- tions in each size interval was geometrically estimated, which requires only its characteristic mobilities. The methodology is applied to mobility measurements from particles charged with unipolar and bipolar chargers. However, the method can be extrapolated to any charging method with a defined charge distribution, and retrieval of the singly charged particle distribution and mean charge from a tandem differential mobility analysis configuration was successfully demonstrated.

关键词： Tandem differential mobility analysisInverse problemregularization methodsSize distributionTransfer functionUnipolar charger

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural regeneration research 2025年第10期20卷 2913-2914页

作者： William j.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

Pregnancy and Metabolic-associated Fatty Liver Disease:A Clinical Update

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journal of Clinical and Translational Hepatology 2022年第5期10卷 947-954页

作者： Sherouk Fouda Madhu Mathew Vennikandam joseph M.Pappachan Cornelius j.fernandez School of Health and Biomedical Sciences RMIT UniversityMelbourneVICAustralia Department of Gastroenterology and Hepatology Sparrow HospitalMichigan State University College of Human MedicineLansingMIUSA Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPrestonUK Faculty of Science Manchester Metropolitan UniversityManchesterUK Faculty of Biology Medicine and HealthThe University of ManchesterManchesterUK Department of Endocrinology&Metabolism Pilgrim HospitalBostonUK

The intricate relationship between metabolic-associated fatty liver disease(MAFLD)and maternal complications has rapidly become a significant health threat in pregnant *** presence of MAFLD in pregnancy increases the maternal risk of metabolic complications and comorbidities for both mother and *** preexistence or development of MAFLD in pregnancy is a complex multifactorial disorder that can lead to further complications for mother and ***,as pregnant women are severely underrepresented in clinical research,there is a great need for a fair inclusion of this group in clinical *** review aims to explore the effects of MAFLD during pregnancy in the context of maternal complications and outcomes and explore the effects of pregnancy on the development and progression of MAFLD within the context of maternal obesity,altered metabolic profiles,gestational diabetes and altered hormonal *** also addressed potential implications for the presence of MAFLD during pregnancy and its management in the clinical setting.

关键词： Metabolic-associated fatty liver disease Pregnancy Maternal complications Fatty liver

Two distinct Paleozoic metamorphic events in the Tarim-North China Collage

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National Science review 2023年第2期10卷 7-8页

作者： jérémie Soldner State Key Laboratory of Isotope Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences CAS Center for Excellence in Deep Earth Science

The Central Asian Or ogenic Belt(CAOB) [1],which includes the Altaids in Central and Northern Asia [2],is the largest accretionary orogen formed during the subduction of the Paleo-Asian Ocean and the Panthalassa Ocean in the period of the Late Proterozoic to Late Paleozoic [3].Closure of the Paleo-Asian Ocean is attributed to the northward drift of the North China and Tarim cratons leading to the massive shortening and oroclinal buckling of the CAOB accretionary system in the Permian [4].

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The effects of patch richness on con-specific interference in the parasitoid Ibalia leucospoides （Hymenoptera： Ibaliidae）

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Insect Science 2010年第4期17卷 379-385页

作者： Valeria fernandez-Arhex juan Carlos Corley Lab. Ecologia de tnsectos INTA EEA-Bariloche Bariloche Rio Negro Argentina

We experimentally studied con-specific interference in Ibalia leucospoides, a parasitoid of the woodwasp Sirex noctilio, on pine logs containing variable numbers of woodwasp larvae. Competiton occurred when two different-sized female parasitoids foraged on a host patch, and consequently the small female always abandoned the patch. regardless of host density, con-specific presence did not affect the attack rate, the number of hosts attacked, nor patch residence time by the winner, when compared to a control female that foraged alone. In contrast, con-specific presence reduced patch time and the number of hosts attacked by the loser. Finally patch time （by both） as well as number of hosts attacked （by the winner only） increased with host density per patch. Our results suggest that con-specific presence has different consequences for different-sized females during patch exploitation.

关键词： aggregation direct competition host-parasitoid interactions parasitoid com-petition patch quality Sirex noctilio

Harnessing artificial intelligence for identifying conflicts of interest in research

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World journal of Methodology 2025年第1期15卷 6-8页

作者： Abdulqadir j Nashwan Department of Nursing&Midwifery research Hamad Medical CorporationDoha 3050Qatar

This editorial explores the transformative potential of artificial intelligence(AI)in identifying conflicts of interest(COIs)within academic and scientific *** harnessing advanced data analysis,pattern recognition,and natural language processing techniques,AI offers innovative solutions for enhancing transparency and integrity in *** editorial discusses how AI can automatically detect COIs,integrate data from various sources,and streamline reporting processes,thereby maintaining the credibility of scientific findings.

关键词： Artificial intelligence Conflicts of interest Transparency research integrity Natural language processing

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural regeneration research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny Cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory HBorschel SickKids research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Alpha-particle decays from excited states in ^(24)Mg

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Science China(Physics,Mechanics & Astronomy) 2011年第S1期54卷 130-135页

作者： LIOTTA r j royal Institute of Technology (KTH) AlbaNova University Center Stockholm S-10691 Sweden

Using a cluster model based on the Woods-Saxon potential, alpha-particle decays from excited states in 24Mg have been system atically investigated. Calculations can in general reproduce experimental data, noticing the fact that the preformation factor P of alpha particle in alpha-decaying nuclei is of order from 100 to 10?2. This can be the evidence for the α+20Ne structure in 24Mg. Meanwhile, the results also show the existence of other configurations, such as 16O+2α. Since the calculated decay widths are very sensitive to the angular momentum carried by the outgoing cluster (α particle), our results could serve as a guide to experimental spin assignments.

关键词： alpha decay cluster structure cluster model 24Mg

A higher-order porous thermoelastic problem with microtemperatures

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Applied Mathematics and Mechanics(English Edition) 2023年第11期44卷 1911-1926页

作者： j.r.FErNáNDEZ r.QUINTANILLA Department of Applied Mathematics I University of VigoETSI de Telecomunicacion Campus As Lagoas Marcosende s/nVigo 36310Spain Department of Mathematics Polytechnical University of CatalunyaTerrassa 08222BarcelonaSpain

In this paper,we study a porous thermoelastic problem with microtemperatures assuming parabolic higher order in time derivatives for the thermal *** model is derived and written as a coupled linear ***,a uniqueness result is proved by using the logarithmic convexity method in the case that we do not assume that the mechanical energy is positive ***,the existence of the solution is obtained by introducing an energy function and applying the theory of linear semigroups.

关键词： higher order thermoelasticity microtemperature logarithmic convexity method existence and uniqueness

General aspects on structural integrity

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Chinese journal of Aeronautics 2019年第1期32卷 114-132页

作者： j.j.XIONG r.A.SHENOI School of Transportation Science and Engineering Beihang University Faculty of Engineering and Environment University of Southampton

This paper seeks to mark the fruitful collaborative research between scholars in the University of Southampton and Beihang University for last 25 years on structural integrity. Their efforts addressed some important issues in structural integrity such as fatigue and fracture behavior,fatigue load spectra, fatigue and fracture lifetimes, reliability-based service period, adhesively bonded composite patch repairs, Plain Woven Fabric(PWF) composites and composite *** advances in engineering approaches, experimental methods, numerical algorithms and understanding of failure mechanisms relating to structural integrity are highlighted. Probable limits(or drawbacks) are also discussed. This review provides an insight into the general aspects on structural integrity and constitutes a basis for pointers to the further works on structural integrity.

关键词： Composites Fatigue Fracture reliability repair Structural integrity