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Europium recovery process by means of polymeric nanoparticles functionalized with acrylic acid,curcumin and fumaramide

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journal of rare Earths 2024年第10期42卷 1950-1959页

作者： P.A.Martínez-Montoya j.M del río A.de j.Morales-ramirez M.Corea Escuela Superior de Ingeniería Química e Industrias Extractivas ESIQIE-IPNDepartamento de Ingeniería Metalúrgica UPALM S/N Col.LindavistaGustao A.MaderoCDMXC.P.07738Mexico Escuela Superior de Ingenieria Química e Industrias Extractivas ESIQIE-IPNLaboratorio de Investigación en Polímeros y NanomaterialesUPALM S/N Col.LindavistaGustavoA.MaderoCDMXC.P.07738Mexico Centra de Investigación e Innovación Tecnológica CIITEC-IPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P.02250CDMXMexico

Polymeric nanoparticles of poly(methyl methacrylate)were obtained by emulsion polymerization techniques in a proce ss of two *** particles were functionalized with acrylic acid,curcumin,and fumaramide and three series of polymeric particles were *** incorporation of functional groups was confirmed by Fourier transform-infrared spectrosocopy(FT-Ir)and ultraviolet-visible(UV-Vis)*** spherical morphology of particles with an average diameter of 100 nm was observed by scartning electron microscopy(SEM).The polymeric materials were used for recovery of[Eu]from synthetic *** nanoparticles show excellent chelation capacity to trap rare-earth ions,because they recover more than 85%of[Eu]at pH of *** images of SEM after extraction process show arrays between particles with larger average particle sizes to 1.5 *** addition,the particles have a good stripping capacity,exceeding 50%of it,maintaining their homogeneity in morphology and good stability in dispersion for the recovery and stripping processes.A pseudo-second model order is obtained for the extraction and stripping processes while the best results of stripping process are obtained at pH of 6.

关键词： [Eu]recovery Chelating effect Extraction process Stripping process Emulsion polymerization rare earths

Unmixing detrital zircon U-Pb ages reveals tectonic and climatic depositional influences on the Carboniferous Ansilta Formation,Calingasta-Uspallata Basin,Western Argentina

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Geoscience Frontiers 2024年第4期15卷 61-77页

作者： j.r.Malone j.E.Malone j.L.Isbell D.H.Malone j.P.Craddock K.N.Pauls Department of Geological Sciences Jackson School of GeosciencesUniversity of Texas at AustinAustinTX 78712USA Iowa Geological Survey University of IowaIowa CityIA 52240USA Department of Geosciences University of Wisconsin-MilwaukeeMilwaukeeWI 53211USA Department of Geography Geology and the EnvironmentIllinois State UniversityNormalIL 61790-4400USA

The Late Paleozoic Ice Age(LPIA)was a principal control of sedimentation across Gondwana from the late Devonian through early *** assess the hypothesis that glacial to interglacial transitions in western Argentina were the primary control influencing sediment routing patterns among the various Carboniferous-Permian basins in western *** Carboniferous Ansilta Formation consists of glaciomarine,nearshore,and fluvial systems deposited during the LPIA along the eastern margin of the Calingasta-Uspallata Basin in *** lower,glacially influenced succession of the Ansilta Formation records at least five glacial advances;the upper succession of consists of progradational shallow marine,deltaic,and fluvial *** combine 1225 new U-Pb zircon ages from six samples of the Carboniferous Ansilta Formation in the Calingasta-Uspallata Basin with 5864 U-Pb ages from 147 pub-lished samples in the detrital Pymix forward mixture model to characterize provenance *** the glacially influenced lower Ansilta Formation,sediment was derived locally from the Protoprecordillera,which was a prominent highland with alpine glaciers flowing west and east into the Calingasta-Uspallata and Paganzo basins,***,there was little or no connection between these two basins during Serpukhovian-Bashkirian *** fluvial/deltaic upper Ansilta had distal sediment sources in the Sierras ***,our results support the collapse of the Protoprecordillera topographic barrier,enabling drainage patterns connecting the Paganzo and Calingasta-Uspallata basins by late Pennsylvanian-early Permian time.

关键词： Late Paleozoic Ice Age Argentina Calingasta-Uspallata Basin Ansilta Formation Detrital zircon provenance

PI3K/Akt/mTOr信号通路在急性淋巴细胞白血病中的靶向治疗现状

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医学综述 2024年第11期30卷 1286-1291页

作者：赖定财毕丽伟许雅苹陈广怡厦门医学院药学系福建厦门361023 厦门医学院基础医学部福建厦门361023 厦门市中药生物工程重点实验室福建厦门361023

磷脂酰肌醇-3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白(PI3K/Akt/mTOr)信号通路广泛参与细胞中多种生命活动进程,是导致癌症产生的重要细胞内信号通路。尽管当前急性淋巴细胞白血病(ALL)的治疗方案已有所改善,但仍有一些患者预后不良。... 详细信息

磷脂酰肌醇-3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白(PI3K/Akt/mTOr)信号通路广泛参与细胞中多种生命活动进程,是导致癌症产生的重要细胞内信号通路。尽管当前急性淋巴细胞白血病(ALL)的治疗方案已有所改善,但仍有一些患者预后不良。因此,探索靶向抑制PI3K/Akt/mTOr信号通路的药物对治疗ALL具有重要意义。目前对于靶向抑制PI3K/Akt/mTOr信号通路的药物研究发展迅速,但仍存在选择性低、易产生耐药性等问题。未来通过对PI3K/Akt/mTOr信号通路在ALL发生发展过程中作用机制的深入研究与联合靶向治疗等方案的探索,有望为ALL的靶向治疗提供新思路,以改善患者预后。

关键词：急性淋巴细胞白血病磷脂酰肌醇-3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白信号通路靶向治疗

超声冲击功率对S355j2G4钢接头组织与性能的影响

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作者： [美]j.r.埃利奥特

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焊接技术 2024年第8期53卷 14-17页

作者：武永利杨志斌车彦龙康金文孙亚鹏中车大同电力机车有限公司山西大同037038 大连交通大学材料科学与工程学院辽宁大连116028

文中基于相同的超声冲击时间采用不同的超声冲击功率对机车车辆用S355j2G4钢焊接接头进行超声冲击处理,系统研究了超声冲击功率对接头微观组织、力学性能和耐磨性能的影响规律。试验结果表明:随超声冲击功率增加,接头表层塑性变形层厚... 详细信息

文中基于相同的超声冲击时间采用不同的超声冲击功率对机车车辆用S355j2G4钢焊接接头进行超声冲击处理,系统研究了超声冲击功率对接头微观组织、力学性能和耐磨性能的影响规律。试验结果表明:随超声冲击功率增加,接头表层塑性变形层厚度增加且晶粒尺寸减小,但超声冲击功率过大将导致接头表层出现损伤;随超声冲击功率增加,接头表层硬度明显增加,但接头的拉伸性能无明显变化;随超声冲击功率增加,接头疲劳性能呈先增加后减小的趋势;随超声冲击功率增加,接头的耐磨性能明显提升。当超声冲击时间6 min时,超声冲击功率50%处理接头的综合性能最佳。

关键词： S355j2G4钢焊接接头超声冲击微观组织力学性能耐磨性能

应用剪切波离散成像斜率值预测移植肾急性排异反应

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国际医学放射学杂志 2024年第5期 620-621页

作者： T.M.Kim H.Ahn j.Y.Cho A.Han S.I .Min j.Ha 郑永利

目的评价剪切波离散成像斜率值预测移植肾功能不全的价值。方法回顾性分析2022年11月—2023年2月期间行肾移植的128例受试者资料[中位年龄，55(43～62)

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射孔密度分布对水平井生产动态的影响

石油勘探与开发 2024年第2期51卷 409-417页

作者： KArEEM Hasanain j HASINI Hasril ABDULWAHID Mohammed A 马来西亚国家能源大学工程学院机械工程系马来西亚加影43000 马来西亚国家能源大学可持续工程研究院马来西亚加影43000 南方工业大学热能工程系伊拉克巴士拉市61001

针对水平井产量受水平井井筒射孔密度分布影响的问题,建立两种水平井射孔密度分布模式(即分别增大井筒入口段和出口段射孔密度)下的数值模型对水平井两相流动进行模拟;将模拟结果与实验结果进行对比,验证本研究数值模拟方法的可靠性,在... 详细信息

针对水平井产量受水平井井筒射孔密度分布影响的问题,建立两种水平井射孔密度分布模式(即分别增大井筒入口段和出口段射孔密度)下的数值模型对水平井两相流动进行模拟;将模拟结果与实验结果进行对比,验证本研究数值模拟方法的可靠性,在此基础上采用数值模拟研究两种射孔密度分布模式下井筒各流型阶段总压降、气水两相流体表观速度、空隙率、液膜厚度和产气量、产液量的变化规律。研究表明,当水相流量保持不变时,随着空气流量的增加,总压降、气水两相流体表观速度增大,空隙率增加,液膜厚度减小;相较于增大出口段射孔密度,当入口段射孔密度增大时,产液量和产气量均增加,且产气量随着气体流量增加而增大;产液量在泡状流阶段增加,而达到弹状流—分层流过渡点后开始降低,进入分层波状流阶段后产液量开始增加;无因次产液量在增大井筒入口段射孔密度的模式下更大,且随着径向气相流量的增加而增大。

关键词：水平井两相流流型射孔密度井筒压降空隙率生产动态

Otolaryngology residency program factors associated with female resident representation

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World journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 7-11页

作者： julia E.Canick james C.Campbell Charles r.Woodard Lars j.Grimm Alissa M.Collins Duke University School of Medicine DurhamNorth CarolinaUSA Department of Head and Neck Surgery&Communication Sciences Duke University School of MedicineDurhamNorth CarolinaUSA Department of radiology Duke University School of MedicineDurhamNorth CarolinaUSA

Objective:Female representation in the field of otolaryngology is *** is the first point at which medical school graduates specialize in a chosen field and thus represents an opportunity to recruit and train more female *** study sought to identify program factors associated with greater female representation among resident ***:Departmental websites of all 124 otolaryngology residency programs in the United States and Puerto rico were examined for a list of *** programs with a resident roster available,the genders of residents,faculty,program directors,and chairpersons were *** and city population for each program was also recorded,as was female resident *** were compared using Pearson Chi‐squared univariate ***:1,632 residents and 2,605 faculty were included in the analysis of 109 *** median female resident representation was 40%.Programs with larger faculty sizes,more female faculty,and urban location were associated with an above‐median female resident *** with a larger residency cohort approached significance regarding above‐median female resident *** female faculty representation,program director gender,chairperson gender,and US region were not associated with variation in female resident ***:Greater female otolaryngology residency representation was associated with programs having an urban location and greater numbers of female and total *** was also likely that a larger resident cohort size may affect female resident *** proportions of female faculty,program director,and chairperson gender,as well as the US region,were not associated with variation in female resident gender representation.

关键词： gender program director recruitment residency training

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桃花心木萜类成分及药理作用的研究进展

热带农业科学 2024年

作者：张飞燕黄玉香赖东珍方荷丽谢梦秋泉州医学高等专科学校药学院

桃花心木[Swietenia mahagoni (L.) jacq.]为楝科桃花心木属植物。在印度、马来西亚等国家传统上用于治疗糖尿病、疟疾、腹泻等疾病。通过CNKI、Pubmed等工具检索桃花心木的萜类成分和药理作用，并对其研究进展进行综述。共检索出94种... 详细信息

桃花心木[Swietenia mahagoni (L.) jacq.]为楝科桃花心木属植物。在印度、马来西亚等国家传统上用于治疗糖尿病、疟疾、腹泻等疾病。通过CNKI、Pubmed等工具检索桃花心木的萜类成分和药理作用，并对其研究进展进行综述。共检索出94种萜类化合物，是其主要的化学成分，以柠檬苦素类化合物最多。主要药理作用有降血糖、抑菌、抗氧化、抑制血小板聚集、杀虫抗疟、抗炎镇痛、保肝、细胞毒性等。然而，桃花心木发挥药理活性的物质基础及其作用机制，还有待进一步研究和论证。本综述为桃花心木进一步药用价值的开发利用提供参考。

关键词：桃花心木萜类成分药理作用研究进展