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Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease

World journal of Hepatology 2016年第27期8卷 1137-1148页

作者： Ilaria Croci Nuala M Byrne Veronique S Chachay Andrew p Hills Andrew D Clouston Trisha M O'Moore-Sullivan johannes B prins Graeme A Macdonald Ingrid j Hickman School of Human Movement and Nutrition Sciences University of Queensland Translational Research Institute the University of Queensland Diamantina Institute Bond Institute of Health and Sport Bond University Institute of Health and Biomedical Innovation Queensland University of Technology School of Health Sciences University of Tasmania Mater Research Institute University of Queensland School of Medi-cine the University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital Translational Research Institute Department of Nutrition and Dietetics Princess Alexandra Hospital

AIM To investigate the independent effects of 6-mo of dietary energy restriction or exercise training on wholebody and hepatic fat oxidation of patients with nonalcoholic fatty liver disease(NAFLD).METHODS participants were randomised into either circuit exercise training(EX;n = 13;3 h/wk without changes in dietary habits),or dietary energy restriction(ER) without changes in structured physical activity(ER;n = 8).Respiratory quotient(RQ) and whole-body fat oxidation rates(Fatox) were determined by indirect calorimetry under basal,insulin-stimulated and exercise *** of disease and steatosis was determined by liver histology;hepatic Fatox was estimated from plasma β-hydroxybutyrate ***;cardiorespiratory fitness was expressed as VO2 ***-case analysis was performed(EX:n = 10;ER:n = 6).RESULTS Hepatic steatosis and NAFLD activity score decreased with ER but not with EX.β-hydroxybutyrate concentrations increased significantly in response to ER(0.08 ± 0.02 mmol/L vs 0.12 ± 0.04 mmol/L,p = 0.03) but remained unchanged in response to EX(0.10 ± 0.03 mmol/L vs 0.11 ± 0.07 mmol/L,p = 0.39).Basal RQ decreased(p = 0.05) in *** EX,while this change was not significant after ER(p = 0.38).VO_(2peak)(p p = 0.03) improved with EX but not with ER(p > 0.05).The increase in β-hydroxybutyrate concentrations was correlated with the reduction in hepatic steatosis(r =-0.56,p = 0.04).CONCLUSION ER and EX lead to specific benefits on fat metabolism of patients with *** hepatic Fat_(ox) in response to ER could be one mechanism through which the ER group achieved reduction in steatosis.

关键词： Non-alcoholic steatohepatitis Steatosis Fat and carbohydrate oxidation Exercise Fitness Beta-hydroxybutyrate Ketone bodies Fatty acid oxidation

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phenotypic nutrient up-take differences in an alley cropping system in semi-arid Machakos, Kenya

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journal of Environmental Sciences 2001年第2期13卷 164-169页

作者： D.N. Mungai C.L.Coulson C.j. Stigter j.K. Ng’ang’a D.N.Mugendi Department of Geography University of NairobiNairdbiKenya Department of Botany University of NairobiNairobiKenya Department of Enviromnental Sciences Graduate School of Productian EcologyWageningen UniversityDuivendaal 26701 APThe Netherlands Department of Meteorology University of NairobiNairobiKenya Kenya Forestry Research Instiute(KEFRI NairobiKanya)

Alley cropping of Cassia siamea and maize was studied in semi arid Kenya for soil fertility improvement. Katumani composite maize was planted except in the short rains of 1988 (SR88) when a hybrid variety was sown. Therefore the grain yield per row increased differently in the alley cropped maize (CM). Sole maize (SM) and CM yields were higher in SR88 than in the long rains of 1988 (LR88) by 62% and 38%, while yields from the same treatments in LR89 were only 21% and 45% of those in SR88 These differences in relative maize yields are attributed to differences between the two maize varieties in competition under nutrient stress conditions.

关键词： alley cropping Cassia siamea maize nutrients maize yield semi arid condition soil moisture Kenya

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法律对裸统计及其他差错的反感

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证据科学 2024年第3期32卷 287-308页

作者： [美]罗纳德·j·艾伦 [美]克里斯托弗·K·斯米克莱斯张嘉源(译) 张保生(校) 西北大学普利兹克法学院国际证据科学协会中国政法大学证据科学研究院外国专家咨询委员会美国西北大学普利兹克法学院中国政法大学证据科学研究院中国政法大学证据科学教育部重点实验室

有大量文献抒发了法律对统计/概率证据的厌烦,尤其是对裸统计证据的排斥。这类文献都是基于错误的前提才持有这样的态度。至少就美国法律而言,人们对统计形式的证明并没有普遍反感,当证据的提供满足了可采性(其中最重要的是可靠性)正常... 详细信息

有大量文献抒发了法律对统计/概率证据的厌烦,尤其是对裸统计证据的排斥。这类文献都是基于错误的前提才持有这样的态度。至少就美国法律而言,人们对统计形式的证明并没有普遍反感,当证据的提供满足了可采性(其中最重要的是可靠性)正常标准时,即使裸统计数据也是可采的,并足以支持裁决。相反的信念是建立在一系列差错基础上的:最重要的是,对法律制度的结构和普通法裁决性质的错误建模。造成这些错误的原因是,这些文献常见的方法论依赖于奇怪的假设,这些假设错误模拟了潜在法律关系,并包含了不可能的认识论要求。总的来说,这些现象分散了人们对影响法律制度的真问题的注意力。

关键词：裸统计概率可采性糟糕证据错误风险

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Tropical cyclone track and intensity prediction skill of GFS model over NIO during 2019&2020

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Tropical Cyclone Research and Review 2022年第1期11卷 36-49页

作者： Ch.Sridevi D.R.pattanaik A.K.Das Akhil Srivastava V.R.Durai C.j.johny Medha Deshpande p.Suneetha Radhika Kanase India Meteorological Department Numerical Weather Prediction DivisionLodhi RoadNew Delhi110003India Indian Institute of Tropical Meteorology MoESPune411008India Dept of Meteorology and Oceanography Andhra UniversityVisakhapatnamAndhra Pradesh530003India

The Tropical Cyclone(TC)track prediction using different NWp models and its verification is the critical task to provide prior knowledge about the model errors,which is beneficial for giving the model guidance-based real-time cyclone warning *** study has attempted to verify the Global Forecast System(GFS)model forecasted tropical cyclone track and intensity over the North Indian Ocean(NIO)for the years 2019 and *** is one of the operational models in the India Meteorological Department(IMD),which provides the medium-range weather forecast up to 10 *** forecasted tracks from the GFS forecast are obtained using a vortex tracker developed by Geophysical Fluid Dynamics Laboratory(GFDL).A total of 13 tropical cyclones formed over the North Indian Ocean,eight during 2019 and five in 2020 have been considered in this *** accuracy of the model predicted tracks and intensity is verified for five days forecasts(120 h)at 6-h intervals;the track errors are verified in terms of Direct position Error(DpE),Along Track Error(ATE)and Cross-Track Error(CTE).The annual mean DpE over NIO during 2019(51–331 km)is lower than 2020(82–359 km),and the DpE is less than 150 km up to 66 h during 2019 and 48 h during *** positive ATE(76–332 km)indicates the predicted track movement is faster than the observed track during both *** positive CTE values for most forecast lead times suggest that the predicted track is towards the right side of the observed track during both *** cyclone Intensity forecast for the maximum sustained wind speed(Max WS)and central mean sea level pressure(MSLp)are verified in terms of mean error(ME)and root mean square error(RMSE).The errors are lead time ***,most of the time model under-predicted the cyclone intensity during both ***,there is a significant variance in track and intensity errors from the cyclone to cyclone and Bay of Bengal basin to the Arabian Sea basin.

关键词： Tropical cyclone Track prediction GFS NWp Global model GFDL

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Ductility improvement of GFRp-RC beams using precast confined concrete block in compression zone

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Frontiers of Structural and Civil Engineering 2023年第10期17卷 1585-1598页

作者： Nooshin G.AMIRABAD Farshid j.ALAEE Meysam jALALI Civil Engineering Department Shahrood University of TechnologyShahrood ***Iran

Fiber-reinforced polymers(FRps)have received considerable research attention because of their high strength,corrosion resistance,and low ***,owing to the lack of ductility in this material and the quasi-brittle behavior of concrete,FRp-reinforced concrete(FRp-RC)beams,even with flexural failure,do not fail in a ductile *** the limited deformation capacity of FRp-RC beams depends on the ductility of their compression zones,the present study proposes using a precast confined concrete block(pCCB)in the compression zone to improve the ductility of the beams.A control beam and four beams with different pCCBs were cast and tested under four-point bending *** control beam failed due to shear,and the pCCBs exhibited different confinements and *** goal was to find an appropriate pCCB for use in the compression zone of the beams,which not only improved the ductility but also changed the failure mode of the beams from shear to *** the employed blocks,a ductile pCCB with low equivalent compressive strength increased the ductility ratio of the beam to twice that of the control *** beam failed in pure flexure with considerable deformation capacity and without significant stiffness reduction.

关键词： ductility four-point bending test glass fiber-reinforced polymer precast confined concrete block

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FAST Observations of an Extremely Active Episode of FRB 20201124A:Ⅰ.Burst Morphology

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Research in Astronomy and Astrophysics 2022年第12期22卷 54-69页

作者： D.j.Zhou j.L.Han B.Zhang K.j.Lee W.W.Zhu D.Li W.C.jing W.-Y.Wang Y.K.Zhang j.C.jiang j.R Niu R Luo H.Xu C.F.Zhang B.j.Wang j.W.Xu p.Wang Z.L.Yang Y.Feng National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy University of Chinese Academy of SciencesBeijing 100049China CAS Key Laboratory of FAST NAOCChinese Academy of SciencesBeijing 100101China Department of physics and Astronomy University of NevadaLas VegasNV 89154USA Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China Department of Astronomy Peking UniversityBeijing 100871China CSIRO Space and Astronomy EppingNSW 1710Australia Research Center for Intelligent Computing platforms Zhejiang LaboratoryHangzhou 311100China

We report the properties of more than 600 bursts(including cluster-bursts)detected from the repeating fast radio burst(FRB)source FRB 20201124A with the Five-hundred-meter Aperture Spherical radio Telescope during an extremely active episode on UTC 2021 September 25–28,in a series of four *** observations were carried out in the band of 1.0–1.5 GHz by using the center beam of the L-band 19-beam *** monitored the source in sixteen1 hr sessions and one 3 hr session spanning 23 *** the bursts were detected during the first four *** this first paper of the series,we perform a detailed morphological study of 624 bursts using the two-dimensional frequencytime“waterfall”plots,with a burst(or cluster-burst)defined as an emission episode during which the adjacent emission peaks have a separation shorter than 400 *** duration of a burst is therefore always longer than 1 ms,with the longest up to more than 120 *** emission spectra of the sub-bursts are typically narrow within the observing band with a characteristic width of~277 *** center frequency distribution has a dominant peak at about 1091.9 MHz and a secondary weak peak around 1327.9 *** bursts show a frequencydownwarddrifting *** on the drifting patterns,we classify the bursts into five main categories:downward drifting(263)bursts,upward drifting(3)bursts,complex(203),no drifting(35)bursts,and no evidence for drifting(121)*** are introduced based on the emission frequency range in the band(low,middle,high and wide)as well as the number of components in one burst(1,2,or multiple).We measured a varying scintillation bandwidth from about 0.5 MHz at 1.0 GHz to 1.4 MHz at 1.5 GHz with a spectral index of 3.0.

关键词： (stars:)pulsars:general physical Data and processes stars:individual(FRB 20201124A)

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Emphysematous pyelonephritis in a Renal Transplant patient

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Open journal of Nephrology 2014年第2期4卷 86-91页

作者： Kashif j. piracha Frank Darras Edward p. Nord Nand K. Wadhwa Division of Nephrology Department of Medicine Stony Brook Medicine Stony Brook USA Transplantation Services Stony Brook Medicine Stony Brook USA

Emphysematous pyelonephritis (EpN) is a necrotizing bacterial infection of the kidney that is caused by gas-forming organisms. We report a case of a 58-year-old man with a renal transplant who presented to the emergency room with nausea, vomiting and right lower quadrant abdominal pain. At the time of presentation, he was hemodynamically stable, and the abdominal examination was significant for tenderness over the allograft. Urinalysis was positive for large amounts of leukocyte esterase and white blood cells. He received empiric antibiotic coverage with piperacillin/tazobactam. Over the following 24 hours, the patient developed septic shock manifested by hemodynamic instability. A non-contrast CT scan of the abdomen and pelvis elucidated a heterogeneous gas containing collection in the allograft. Emergent transplant nephrectomy was performed. postoperatively, the patient rapidly recovered and was subsequently discharged home to commence outpatient hemodialysis. A review of the literature suggests that early recognition of the severity of EpN as manifested by hemodynamic instability dictates emergent transplant nephrectomy as the treatment of choice.

关键词： Emphysematous pyelonephritis Kidney Allograft Transplant

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A comparison study of Ce/La and Ca microalloying on the bio-corrosion behaviors of extruded Mg-Zn alloys

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journal of Magnesium and Alloys 2020年第4期8卷 1269-1280页

作者： j.H.Chu L.B.Tong Z.H.jiang D.N.Zou Q.j.Wang S.F.Liu H.j.Zhang School of Metallurgical Engineering Xi'an University of Architecture and TechnologyXi'an 710055China State Key Laboratory of Rare Earth Resources Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Key Lab of Automobile Materials College of Materials Science and EngineeringJilin UniversityNanling CampusChangchun 130025China

The influences of Ca and Ce/La microalloying on the microstructure evolution and bio-corrosion resistances of extruded Mg-Zn alloys have been systematically investigated in the current *** with single Ca or Ce/La addition,the Ca-Ce/La cooperative microalloying results in an outstanding grain refinement,because the fine secondary phase particles effectively hinder the recrystallized grain *** coarse Ca2Mg6Zn3 phases promote the formation of Ca3(pO4)2 or hydroxyapatite particles during the immersion process and accelerate the dissolution of the corrosion product film,which destroys its integrity and results in the deterioration of anti-corrosive *** Ce/La elements can be dispersed within the conventional Mg7Zn3 phases,which reduce the internal galvanic corrosion between Mg matrix and the secondary phases,leading to an obvious improvement of corrosion ***,the Ca-Ce/La cooperative microalloying achieves a homogenous fine-grained microstructure and improves the protective ability of surface film,which will pave a new avenue for the design of biomedical Mg alloys in the coming future.

关键词： Extruded Mg-Zn alloy Ca and Ce/La microalloying Microstructure evolution Bio-corrosion behaviors

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On Approximation by Interpolating polynomials in Cωp Spaces

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journal of Mathematical Research with Applications 1993年第3期 465-469页

作者： S.p.Zhou Dept.of Math. Univ.of Alberta Edmonton Alberta Canada T6G 2G1

This note gives a counterexample which in particular shows that a mainresult of a paper in *** is not correct.

关键词： p Spaces On Approximation by Interpolating polynomials in C

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Duplicate publication bias weakens the validity of metaanalysis of immunosuppression after transplantation

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World journal of Gastroenterology 2017年第39期23卷 7198-7200页

作者： Cameron j Fairfield Ewen M Harrison Stephen j Wigmore Department of Clinical Surgery University of Edinburgh Royal Infirmary of Edinburgh

Duplicate publication can introduce significant bias into a meta-analysis if studies are inadvertently included more than once. Many studies are published in more than one journal to maximize readership and impact of the study findings. Inclusion of multiple publications of the same study within a meta-analysis affords inappropriate weight to the duplicated data if reports of the same study are not linked together. As studies which have positive findings are more likely to be published in multiple journals this leads to a potential overestimate of the benefits of an intervention. Recent advances in immunosuppression strategies following liver transplantation have led to many studies investigating immunosuppressive regimes including immunosuppression monotherapy. In this letter we focus on a recently published meta-analysis by Lan et al investigating studies assessing immunosuppression monotherapy for liver transplantation. The authors claim to have identified fourteen separate randomised studies investigating immunosuppression monotherapy. Seven of the references appear to relate to only three studies which have been subject to duplicate publication. Several similarities can be identified in each of the duplicate publications including similar authorship, identical immunosuppression regimes, identical dates of enrolment and citation of the original publication in the subsequent manuscripts. We discuss the evidence of the duplicate publication inclusion in the meta-analysis.

关键词： Liver transplantation Immunosuppression Meta-analysis Duplicate publication Bias

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