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与斑贴试验反应强度有关的副-苯二胺过敏患者的分析

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世界核心医学期刊文摘（皮肤病学分册） 2005年第11期1卷 35-35页

作者： Ho S.G.Y. Basketter D.A. jefferies D. j.p. mcfadden 刘艳 Dr. Contact Dermatitis Clinic St. John's Institute of Dermatology St. Thomas'Hospital Lambeth Palace Rd London SE1 7EH United Kingdom

Background: Despite having a positive patch test reaction to para-phenylenediamine (ppD), some patients continue to dye their hair, while others are forced to give up or abandon this practice. This difference in patient behaviour could be due to the degree of sensitization. Objectives: To establish whether the ability to continue dyeing hair in ppD allergic patients is related to the strength of patch test reaction. To note differences in other clinical features in relation to the strength of patch test reaction. Methods We analysed retrospectively the patch test records of 400 sequential ppD-positive patients for the strength of patch test reaction (+, ++, +++) and different clinical features. Data were analysed using Cochran-Mantel-Haenszel χ2 tests. Results: There was a strong linear relationship between the strength of patch test reaction and continuation with hair dyeing. patients were more likely to report a history of hair dye reaction with increasing strength of patch test reaction. There was no difference in strength of patch test reaction in relation to age, site of rash, occupation (hairdressing) or history of atopic eczema. Overall concomitant reactivity with related aromatic amine allergens (benzocaine,N-isopropyl-Nphenyl-para-phenylenediamine, para-aminobenzoic acid) was infrequent. Conclusions: patients with stronger patch test reactions (++, +++) are more likely to have a clear history of reacting to hair dye and are less likely to still be dyeing their hair.

关键词：斑贴试验过敏患者苯二胺反应强度特应性皮炎发疹苯佐卡因 Cochran 线性关系数据分析

干旱—半干旱环境晚第三纪-第四纪气候变迁的地貌和地层标志

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干旱区地理 1990年第1期13卷 64-64,61页

作者： j.C.Dohrenwend S.G.Wells L.D.mcfadden 艾东

1985年4月在美国亚利桑那州哈瓦苏湖城(Lake Havasu City)召开了彭罗斯会议(penrose Cenference),会议就干旱区地貌和地表沉积的气候变迁效应及其敏感标志进行了广泛的讨论。

关键词：干旱-半干旱环境晚第三纪第四纪古气候变化地层标志地貌

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利尿酸是打开血-迷路屏障的钥匙

中华耳科学杂志 2004年第1期2卷 42-47页

作者：丁大连蒋海燕 Sandra L.mcfadden Richard j.Salvi 美国纽约州立大学布法罗听力研究中心

目的观察在不同的时机应用利尿酸以暂时破坏耳蜗血管纹上皮是否能够开放血-迷路屏障,从而促使庆大霉素进入耳蜗或者从耳蜗排出。方法听神经动作电位测试技术,全耳蜗毛细胞计数定量观察技术和荧光偏振免疫法测定庆大霉素浓度的技术被用... 详细信息

目的观察在不同的时机应用利尿酸以暂时破坏耳蜗血管纹上皮是否能够开放血-迷路屏障,从而促使庆大霉素进入耳蜗或者从耳蜗排出。方法听神经动作电位测试技术,全耳蜗毛细胞计数定量观察技术和荧光偏振免疫法测定庆大霉素浓度的技术被用于以下两个不同目的的实验观察。(1)当庆大霉素血中浓度高于内耳液浓度时,应用利尿酸破坏蜗管外壁以促使更多的庆大霉素进入耳蜗以制备不同程度耳蜗损害的动物模型。(2)当庆大霉素内耳浓度高于血中浓度时,应用利尿酸损坏蜗管外壁以促使蓄积在耳蜗内的庆大霉素从内耳排出以达到挽救毛细胞的目的。结果1郾当庆大霉素血中浓度高于内耳液浓度时,注射利尿酸可造成更多的毛细胞损害和听功能障碍,外淋巴中药物的峰值浓度和半衰期浓度也均比单独一次注射庆大霉素动物外淋巴中药物浓度增加一倍,说明同时注射利尿酸可促使更多的庆大霉素从血液进入耳蜗并造成更严重的毛细胞损害。2郾当血液中庆大霉素排空之后,注射利尿酸可减少毛细胞数量的损失程度,同时发现延迟注射利尿酸组动物的听力损失程度比不经利尿酸处理动物组有所减轻,外淋巴中药物浓度也比不经利尿酸处理动物组降低一半,说明当GM在耳蜗内蓄积但血清中已经排空时注射EA有助于降低药物在耳蜗内的蓄积并挽救尚未被破坏的毛细?

关键词：利尿酸血-迷路屏障中药庆大酶素耳毒性药物浓度 EA

RETINOIC ACID AND THE CONTROL OF SCLERAL STRUCTURE IN A MAMMALIAN MODEL OF MYOpIA

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RETINOIC ACID AND THE CONTROL OF SCLERAL STRUCTURE IN A MAMM...

On the retreat of near-Earth neutral line during substorm expansion phase:a THEMIS case study during the 9 january 2008 substorm

第十八届国际眼科研究大会

作者： S.A mcfadden E Stockings A Leotta D.M Schwartz M.S Mattson j.A Kornfield School of psychology The University of NewcastleAustralia

＜正＞When a growing eye wears a negative or positive spectacle lens,it will increase or decrease its growth rate respectively to compensate for the imposed *** have developed a mammalian model of such spectacle lens compensation（SLC）using the guinea *** this model,minus lenses induce excessive elongation and myopia,while plus lenses inhibit ocular growth and eyes develop relative *** is known

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On the retreat of near-Earth neutral line during substorm ex...

Fast tailward flows in the plasma sheet boundary layer during a substorm on 9 March 2008:THEMIS observations

中国科学院地质与地球物理研究所2012年度（第12届）学术年会

作者： X.Cao Z.Y.pu A.M.Du V.M.Mishin X.G.Wang C.j.Xiao T.L.Zhang V.Angelopoulos j.p.mcfadden K.H.Glassmeier Institute of Geology and Geophysics Chinese Academy of Sciences School of Earth aod Space Sciences Peking University Institute of Solar-Terrestrial physics Russian Academy of Sciences School of physics Peking University Department of Geophysics and planetary Sciences USTC Space Research Institute Austrian Academy of Sciences Department of Earth and Space Sciences and Institute of Geophysics and planetary physics University of California Space Sciences Laboratory University of California TUBS Max-planck-Institut fr Sonnensystemforschung Katlenburg-LindauGermany

The location of magnetic reconnection in the midtail during a substorm was studied in many *** we present multi-point THEMIS observations of a reconnection event in the near-Earth magnetotail during *** this event,THEMIS probes stayed in the near-Earth and midtail region aligning along the *** allows reconnection evolution to be probed simultaneously from about -10 R to -23 R down *** Hall current related electron streams were observed at the same time by two probes far away from the reconnection *** near-Earth reconnection involved the tail lobe magnetic field,the reconnection site was restricted in earthward -23 *** reconnection involved into the tail lobe region,the reconnection site started to retreat gradually.

关键词： Magnetospheric physics(Magnetotail Storms and substorms)- Space plasma physics(Magnetic reconnection)

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Fast tailward flows in the plasma sheet boundary layer durin...

THEMIS observations of two substorms on February 26,2008

中国科学院地质与地球物理研究所第11届（2011年度）学术年会

作者： R.Nakamura E.V.panov W.Baumjohann M.Volwerk A.Retino B.Zieger V.Angelopoulos K.-H.Glassmeier j.p.mcfadden D.Larson Space Research Institute Austrian Academy of Sciences GrazAustria Institute of Geophysics and planetary physics University of Califomia Los AngelesCaliforniaUSA Institut fr Geophysik und extraterrestrische physik Technische Universitt Braunschweig BrunswickGermany Space Science Laboratory University of California BerkeleyCaliforniaUSA

[1]Tailward flows in the plasma sheet boundary layer(pSBL) were observed simultaneously by the five Time History of Events and Macroscale Interactions during Substorms(THEMIS) probes at down-tail distances X.6 to 7.6 R for 0 min during an interval of successive substorm intensification in a storm time on 9 March 2008. The flows first occurred close to Earth and then propagated along the magnetic field lines in the pSBL with a speed of 50-350 km *** show that the occurrence of tailward flows is highly dependent on proximity to the plasma sheet *** speeds occurred in the outer part of the pSBL,while either lower tailward speeds(or even earthward flows) were seen in the inner part of the *** tailward flow occurrence increased during magnetotail stretching and decreased or ceased during magnetic field *** pSBL tailward flows near the Earth can be understood as an outflow of the earthward flows that essentially empty the central plasma *** tailward flows along the field line filled the void left behind by the dipolarization front.

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Science China(Technological Sciences) 2010年第5期53卷 1328-1337页

作者： CHU XiangNing pU ZuYin CAO Xin WANG jue V.MISHIN V.ANGELOpOULOS LIU jiang WEI Yong K.H.GLASSMEIER j.mcfadden D.LARSON S.MENDE H.FREY C.T.RUSSELL I.MANN D.SIBECK ZONG QiuGang FU SuiYan XIE Lun T.I.SAIFUDINOVA M.V.TOLOCHKO L.A.SApRONOVA H.REME E.LUCEK School of Earth and Space Sciences Peking UriiversityBeijing 100871China Institute of Solar-Terrestrial physics Russian Academy of Sciences IGpp UCLA Instiute of Geophysics and Extraterrestrial physics Technical University of BraunschweigBraunschweig and Max Planck Institute of Solar System Research Space Sciences Laboratory University of California Department of physics University of Alberta Code 674 NASA/GSFC Centre d'Etude Spatiale des Rayonnements Blackett Laboratory Imperial College London

Two substorms occurred at ～04:05 and ～04:55 UT on February 26,2008 are studied with the in-situ observations of THEMIS satellites and ground-based aurora and magnetic field *** et *** made a comprehensive study of the 04:55 UT *** showed detailed features of the two substorms with much attention to the first event and to the rela-tionship between mid-tail magnetic reconnection(MR) and substorm *** was found that in the earlier stage of each substorm,a first auroral intensification occurred 2-3 min soon after the start of mid-tail MR,followed by a slow and very lim-ited *** auroral arcs were weak,short-lived,and localized,characterizing all features of a *** re-garded the first auroral brightening as the initial onset of the substorms.A few minutes later,a second stronger auroral intensification appeared,followed by quick and extensive *** was interesting to note that the second brightening and related poleward expansion happened almost simultaneously(within a couple of minutes) with the onset of earthward flow and dipolarization in the near-Earth tail and other phenomenon of the substorm expansion *** thus regarded the second auroral brightening as the major onset of the ***,it was seen that during the growth phase of the two substorms,the polar cap open flux Ψ kept increasing,while it quickly reduced during the substorm expansion and recovery *** variations of Ψ implied that the evolution of the two substorm expansion phases were closely related to MR of tail lobe open field *** of substorm activities revealed that the two events studied were small substorms;while estimate of MR rate indicated that the MR processes in the two substorms were *** aforementioned observations suggested that mid-tail MR initiated the pseudobreakup first;the earthward flow generated by MR transported magnetic flux and energy to the near-Earth tail to cause the formatio

关键词： substorm auroral intensification/brightening auroral expansion dipolarization magnetic reconnection

Late Quaternary paleoenvironments of ancient Lake Mojave-reconstructing the history from stratigraphy,sedimentology,soils,geomorphology and radiocarbon dating plus some modeling on the paleohydrology

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地球环境学报 2011年第1期 326-326页

作者： Wells S G Enzel Y Brown W j Anerson R Y mcfadden L D Desert Research Institute Institute of Earth Sciences Hebrew University of Jerusalem Dames and Moore Inc. Department of Earth and planetary Sciences University of New Mexico

Late Quaternary fluctuations of pluvial Lake Mojave are recorded in subsurface,cored lake deposits and shoreline features in the terminal depositional basins(Silver Lake and Soda Lake) of the Mojave *** Mojave was one of two large late Quaternary lakes sustained by the Mojave River with the other being the upstream Lake *** Lake Depositional Basin(SiLDB) contains a high resolution stratigraphic sequence due to its shallowness and minimal relief across the pre-lake basin *** building in SiLDB began at22 ka with two major high and persistent lake stands occurring between18.4 ka and16.6 ka(LMI) and13.7 ka and11.4 ka(LMII).Overflow from Lake Manix sustained LMI which stabilized at the A-shoreline(elevation 287288 m).LMII coincided with breaching and draining of Lake Manix,reducing the storage capacity of Lake Mojave,increasing its evaporative surface area,and enhancing overflow from Lake Mojave into Death *** overflow downcut the Lake Mojave outlet spillway between 12 ka and 11 ka,ultimately stabilizing at an elevation of 285.5 m(B-shoreline).The majority of shoreline features currently found around the margins of Silver Lake and Soda Lake date to LMII/B-shoreline,as the shallow lake conditions resulted in erosion of older LMI *** also experienced alternating periods of intermittent lake conditions and periods of desiccation some during higher stands and more continuous Lake Mojave phases with a significant drying event occurring15.5 *** drying of Lake Mojave occurred by8.7 ka,with playa conditions dominating the *** the history of lake level elevations and a simplified,precipitationdischarge/evaporation model,we infer that the late pleistocene hydrologic conditions resulting in Lake Mojave overflow at Spillway bay in Silver Lake lie between two sets of conditions:(1) a 50%increase in precipitation in the headwater catchment resulting in annual flood events reaching SiLDB with discharges three times that of the

关键词： Lake Late Quaternary paleoenvironments of ancient Lake Mojave-reconstructing the history from stratigraphy,sedimentology,soils,geomorphology and radiocarbon dating plus some modeling on the paleohydrology

《美国经济评论》创刊100年来的20篇最佳文章

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经济资料译丛 2011年第3期 1-6页

作者： Kenneth j.Arrow B.Douglas Bernheim Martin S.Feldstein Daniel L.mcfadden james M.poterba Robert M.Solow 吴春雷马林梅斯坦福经济政策研究所斯坦福大学经济系美国经济研究局加州大学经济系麻省理工学院经济系辽宁工程技术大学工商管理学院邮政编码125105

由Kenneth j. AITOW, B. Douglas Bernheim, Martin S. Feldstein, Daniel L. mcfadden,james *** 和Robert M. Solow组成的20佳文章评选委员会，受Robert教育Moffitt的委命，负责评选《美国经济评论》创刊100年以来所刊发的最优秀的20... 详细信息

关键词：《美国经济评论》文章创刊 Daniel james 委员会评选