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Assessment of ECMWF’s Precipitation Forecasting Performance for China from 2017 to 2022

journal of Tropical Meteorology 2024年第3期30卷 257-274页

作者： PAN Liu-jie ZHANG Hong-fang LIANG Mian LIU jia-huimin DAI chang-ming Shaanxi Meteorological Observatory Xi’an 710014 China key Laboratory of Eco-Environment and Meteorology for the Qinling Mountains and Loess Plateau Xi’an 710014 China Shaanxi Meteorological Service Centre Xi’an 710014 China

This study used the China Meteorological Administration(CMA)three-source fusion gridded precipitation analysis data as a reference to evaluate the precipitation forecast performance of the European Centre for Medium-Range Weather Forecasts(ECMWF)model for China from 2017 to *** main conclusions are as *** precipitation forecast capability of the ECMWF model for China has gradually improved from 2017 to *** scores such as bias,equitable threat score(ETS),and Fractions Skill Score(FSS)showed improvements for different categories of *** bias of light rain forecasts overall adjusted towards smaller values,and the increase in forecast scores was greater in the warm season than in the cold *** ETS for torrential rain more intense categories significantly increased,although there were large fluctuations in bias across different *** model exhibited higher precipitation bias in most areas of North China,indicating overprediction,while it showed lower bias in South China,indicating *** ETSs indicate that the model performed better in forecasting precipitation in the northeastern part of China without the influence of climatic background *** of the differences between the first period and the second period of the forecast shows that the precipitation amplitude in the ECMWF forecast shifted from slight underestimation to overestimation compared to that of CMPAS05,reducing the likelihood of missing extreme precipitation *** improvement in ETS is mainly due to the reduction in bias and false alarm rates and,more importantly,an increase in the hit *** 2017 to 2022,the area coverage error of model precipitation forecast relative to observations showed a decreasing trend at different scales,while the FSS showed an increasing trend,with the highest FSS observed in *** ETS followed a parabolic trend with increasing neighborhood radius,with the better ETS neighborhood radius generally

关键词： ECMWF forecasting verification neighborhood verification FSS

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Creep rupture life predictions for Ni-based single crystal superalloys with automated machine learning

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Rare Metals 2024年第6期43卷 2884-2890页

作者： chang-Lu Zhou Rui-Hao Yuan Wei-jie Liao Ting-Huan Yuan jiang-kun Fan Bin Tang Ping-Xiang Zhang jin-Shan Li Turab Lookman State key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi'an 710072China Chongqing Innovation Center Northwestern Polytechnical UniversityChongqing 401120China AiMaterials Research LLC Santa FeNM 87501USA

The state of the art for data-driven creep rupture life predictions incorporates microstructural and deformation characteristics into machine ***,the microstructures and deformation mechanisms for unknown alloys are inaccessible and uncertain before experiments are carried out,and therefore prevents extrapolations of the learned models.

关键词： deformation life creep

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Molecular phylogenetic relationships based on mitochondrial genomes of novel deep-sea corals(Octocorallia:Alcyonacea):Insights into slow evolution and adaptation to extreme deep-sea environments

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Zoological Research 2024年第1期45卷 215-225页

作者： Zhan-Fei Wei kai-Wen Ta Nan-Nan Zhang Shan-Shan Liu Liang Meng kai-Qiang Liu Chong-Yang Cai Xiao-Tong Peng chang-Wei Shao National key Laboratory of Mariculture Biobreeding and Sustainable Goods Yellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesQingdaoShandong 266071China BGI-Qingdao BGI-ShenzhenQingdaoShandong 266555China Institute of Deep-Sea Science and Engineering Chinese Academy of SciencesSanyaHainan 572000China

A total of 10 specimens of Alcyonacea corals were collected at depths ranging from 905 m to 1633 m by the manned submersible Shenhai Yongshi during two cruises in the South China Sea(SCS).Based on mitochondrial genomic characteristics,morphological examination,and sclerite scanning electron microscopy,the samples were categorized into four suborders(Calcaxonia,Holaxonia,Scleraxonia,and Stolonifera),and identified as 9 possible new cold-water coral *** of GC-skew dissimilarity,phylogenetic distance,and average nucleotide identity(ANI)revealed a slow evolutionary rate for the octocoral mitochondrial *** nonsynonymous(ka)to synonymous(ks)substitution ratio(ka/ks)suggested that the 14 protein-coding genes(PCGs)were under purifying selection,likely due to specific deep-sea environmental *** analysis of the median ka/ks values of five gene families and environmental factors indicated that the genes encoding cytochrome b(cyt b)and DNA mismatch repair protein(mutS)may be influenced by environmental factors in the context of deep-sea species *** study highlights the slow evolutionary pace and adaptive mechanisms of deep-sea corals.

关键词： Mitochondrial genome Alcyonacea ka/ks evolution Environmental factors

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Leptonic di-flavor and di-number violation processes at high energyμ^(±)μ^(±)colliders

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Chinese Physics C 2024年第4期48卷 34-50页

作者：杨金磊张肇西冯太傅 CAS key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Physical Science and Technology Lanzhou UniversityLanzhou 730000China Department of Physics Hebei UniversityKey Laboratory of High-precision Computation and Application of Quantum Field Theory of Hebei ProvinceBaoding 071002China

The leptonic di-flavor violation (LFV) processes μ^(±)μ^(±)→e^(±)e^(±) and μ^(±)μ^(±)→τ^(±)τ^(±) and leptonic di-number violation (LNV) processes μ^(±)μ^(±)→W_(i)^(±)W_(j)^(±) (i,j=1,2) at same-sign high energy μ^(±)μ^(±) colliders are studied. The new physics (NP) factors that may play roles in these processes are highlighted by cataloging them into three types. Taking into account the experimental constraints, the processes at μ^(±)μ^(±) colliders are computed, and the results are presented properly. The results lead to the conclusion that observing the NP factors through the LFV and LNV processes at TeV-energy μ^(±)μ^(±) colliders has significant advantages that cannot be achieved elsewhere. Therefore, once the techniques for muon acceleration and collision are developed successfully, the option of building same-sign high energy muon colliders should be seriously considered.

关键词： μ^(±)μ^(±)collider neutral lepton Majorana components

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Discovery of a potential bladder cancer inhibitor CHNQD-01281 by regulating EGFR and promoting infiltration of cytotoxic T cells

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Marine Life Science & Technology 2024年第3期6卷 502-514页

作者： jian-Yu Liu Yao-Yao jiang Peng-jie Li Bo Yao Yi-jing Song ji-Xiu Gao Gulab Said Yang Gao jun-Yu Lai chang-Lun Shao key Laboratory of Marine Drugs the Ministry of Education of ChinaSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China Department of Critical Care Medicine the Affiliated Hospital of Qingdao UniversityQingdao 266003China Department of Chemistry Women University SwabiSwabi 23430Pakistan Laoshan Laboratory Qingdao 266237China key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education College of Chemistry and Chemical EngineeringHainan Normal UniversityHaikou 571158China

As one of the common malignancies that threaten human life,bladder cancer occurs frequently with a high mortality rate in the world,due to its invasion,recurrence and drug *** products from marine microorganisms are becoming the hotspots in discovery of new candidate drug entities,especially in the area of *** A(BFA)is a natural Arf-GEFs inhibitor,but due to the low aqueous solubility,strong toxicity,and poor bioavailability,it is urgent to conduct structural optimization ***,a new BFA pyridine acrylate derivative CHNQD-01281 with improved solubility was prepared and found to exert moderate to strong antiproliferative activity on a variety of human cancer cell *** was noteworthy that CHNQD-01281 was most sensitive to two bladder cancer cell lines T24 and j82(IC50=0.079 and 0.081μmol/L)with high selectivity index(SI=14.68 and 14.32),suggesting a superior safety to *** vivo studies revealed that CHNQD-01281 remarkably suppressed tumor growth in a T24 nude mice xenograft model(TGI=52.63%)and prolonged the survival time(ILS=68.16%)in an MB49 allogeneic mouse model via inducing infiltration of cytotoxic T *** mechanism exploration indicated that CHNQD-01281 regulated both EGFR/PI3k/AkT and EGFR/ERk pathways and mediated the chemotactic effect of chemokines on immune effector ***,CHNQD-01281 may serve as a potential therapeutic agent for bladder cancer through multiple mechanisms.

关键词： Bladder cancer Marine natural products Brefeldin A EGFR/PI3k/AkT EGFR/ERk T-cell infiltration

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Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa

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Neural Regeneration Research 2024年第11期19卷 2543-2552页

作者： Sam Enayati karen chang Anton Lennikov Menglu Yang Cherin Lee Ajay Ashok Farris Elzaridi Christina Yen kasim Gunes jia Xie kin-Sang Cho Tor Paaske Utheim Dong Feng Chen Schepens Eye Research Institute of Massachusetts Eye and Ear Department of OphthalmologyHarvard Medical SchoolBostonMAUSA Institute of clinical medicine Faculty of MedicineUniversity of OsloOsloNorway Department of Medical Biochemistry Oslo University HospitalUniversity of OsloOsloNorway Department of Ophthalmology Drammen HospitalVestre Viken Hospital TrustDrammenNorway Department of Histology and Embryology School of MedicineMarmara UniversityIstanbulTurkiye

Retinitis pigmentosa is a hereditary retinal disease that affects rod and cone photoreceptors,leading to progressive photoreceptor *** research supports the beneficial effect of electrical stimulation on photoreceptor *** study aims to identify the most effective electrical stimulation parameters and functional advantages of transcorneal electrical stimulation(tcES)in mice affected by inherited retinal ***,the study seeked to analyze the electric field that reaches the retina in both eyes in mice and post-mortem *** this study,we recorded waveforms and voltages directed to the retina during transcorneal electrical stimulation in C57BL/6j mice using an intraocular needle probe with rectangular,sine,and ramp *** investigate the functional effects of electrical stimulation on photoreceptors,we used human retinal explant cultures and rhodopsin knockout(Rho^(-/-))mice,demonstrating progressive photoreceptor degeneration with *** retinal explants isolated from the donors’eyes were then subjected to electrical stimulation and cultured for 48 hours to simulate the neurodegenerative environment in *** density was evaluated by rhodopsin *** vivo Rho^(-/-)mice were subjected to two 5-day series of daily transcorneal electrical stimulation using rectangular and ramp *** function and visual perception of mice were evaluated by electroretinography and optomotor response(OMR),*** was used to assess the morphological and biochemical changes of the photoreceptor and bipolar cells in mouse *** recordings indicated effective delivery of rectangular,sine,and ramp waveforms to the retina by transcorneal electrical stimulation,of which the ramp waveform required the lowest *** of the total conductive resistance of the post-mortem human compared to the mouse eyes indicated higher cornea-to-retina resistance in human *** tem

关键词： bipolar cells electrical stimulation neuroprotection photoreceptor degeneration retina retinal explants retinitis pigmentosa transcorneal electrical stimulation waveform

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Achieving a remarkable low-temperature tensile ductility in a high-strength tungsten alloy

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Tungsten 2024年第1期6卷 150-161页

作者： Xiang Cheng Zhuo-Ming Xie Xue-Feng Xie Long-Fei Zeng Rui Liu jun-Feng Yang Xue-Bang Wu Xian-Ping Wang chang-Song Liu Qiang-Feng Fang key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China Faculty of Materials Metallurgy and Chemistry Jiangxi University of Science and TechnologyGanzhou 341000China

Hot-swaging yields a high ultimate tensile strength of 712 MPa but a limited tensile ductility with the total elongation of3.6%at a testing temperature of 200℃in a representative W-0.5wt.%ZrC *** this work,the evolution of Vickers microhardness with annealing temperatures is investigated in detail,which contributes to a rough index chart to guide the search for an optimized post-annealing *** the post-annealing around 1300℃,an outstanding tensile ductility at200℃,including a uniform elongation of 14%and a total elongation of~25%,has been achieved without the sacrifice of its *** evolution of dislocations and grain structures with the annealing temperatures accessed through backscattered scanning electron microscope and transmission electron microscope analysis reveals that the improved low-temperature tensile ductility has resulted from the reduction of residual dislocations and dislocation tanglement via the static recovery,which provides more room to accommodate dislocations,and hence stronger strain hardening ability and tensile ductility.

关键词： Tungsten Low-temperature ductility Annealing Dislocations

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基础摆动条件下电磁轴承-柔性转子系统的加速度前馈振动抑制

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振动工程学报 2024年第8期37卷 1269-1280页

作者：张鹏祝长生浙江大学电气工程学院浙江杭州310027

旋转机械基础的摆动会给转子系统带来附加的陀螺力矩和惯性载荷,影响转子系统的振动及稳定性,甚至影响转子的正常运行。为了有效控制电磁轴承‐柔性转子系统在基础摆动下的振动,提出了一种基于基础加速度的前馈补偿控制方法。该方法基... 详细信息

旋转机械基础的摆动会给转子系统带来附加的陀螺力矩和惯性载荷,影响转子系统的振动及稳定性,甚至影响转子的正常运行。为了有效控制电磁轴承‐柔性转子系统在基础摆动下的振动,提出了一种基于基础加速度的前馈补偿控制方法。该方法基于柔性转子系统动力学模型以及基础摆动的信息,可直接得到抑制转子振动所需的最佳补偿电流,无需迭代和复杂的控制器结构,因此具有较强的快速性和实用性。为了消除建模误差对前馈补偿控制性能的影响,给出了对补偿电流进行修正的方法。仿真分析了补偿算法对转子振动的抑制效果。在搭建的电磁轴承‐柔性转子系统基础运动试验平台上,进行了基础摆动条件下转子悬浮、恒速、加速运行时的振动控制有效性试验。理论和试验结果一致,表明基础摆动产生的附加惯性载荷会使电磁轴承‐柔性转子系统在垂直于摆动方向上的振动明显增大,产生的附加陀螺力矩会使沿摆动方向的振动有所增大,且增加的幅度随转子转速的升高而增大。在包含一阶弯曲临界转速的转速范围内,基础加速度前馈补偿控制对基础摆动条件下的转子振动均有显著的抑制效果。

关键词：振动抑制电磁轴承基础摆动前馈补偿

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层状地基中海洋大直径管桩水平动力响应分析

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岩土力学 2024年第6期45卷 1873-1883页

作者：林浩郑长杰丁选明福建理工大学福建省土木工程新技术与信息化重点实验室福建福州350118 福建理工大学土木工程学院福建福州350118 重庆大学土木工程学院重庆400045

考虑桩−海水−层状土相互作用,研究了水平动荷载作用下层状地基中海洋大直径管桩的动力响应特性。将海水视为无黏性可压缩流体介质建立桩周、桩芯海水的运动方程,通过分离变量法并结合海水的边界条件求得桩周、桩芯海水作用在管桩上的动... 详细信息

考虑桩−海水−层状土相互作用,研究了水平动荷载作用下层状地基中海洋大直径管桩的动力响应特性。将海水视为无黏性可压缩流体介质建立桩周、桩芯海水的运动方程,通过分离变量法并结合海水的边界条件求得桩周、桩芯海水作用在管桩上的动水压力。将海床土体视为黏弹性介质并考虑其成层非均质性,利用微分变化并结合土体振动边界条件解得桩周、桩芯土体作用在管桩上的水平抗力。进而根据各桩段上水平力的平衡建立管桩控制方程,利用传递矩阵法并结合桩身的连续条件以及桩顶、桩底的边界条件,得到层状海床土中海洋大直径管桩的水平动力响应解析解,给出了桩顶位移解析表达式。将所得解与有限元模拟结果以及退化解与已有文献解进行对比,验证了本研究计算方法的合理性。并基于所得解分析了管桩−海水−层状土系统水平动力响应对动水压力、水深、土体模量、土层厚度等关键参数的敏感性。

关键词：桩顶位移海洋大直径管桩水平振动特性桩芯海水层状海床地基

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铸牢中华民族共同体意识的法学教育路径

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民族教育研究 2024年第2期35卷 13-19页

作者：常安毛荣西北政法大学法治与中华民族共同体建设研究中心陕西西安710063

法学教育应当坚决贯彻铸牢中华民族共同体意识的主线地位,也可成为铸牢中华民族共同体意识的重要实践路径。新时代法学教育需要服务于国家铸牢中华民族共同体意识、依法治理民族事务大局,引导法科学生铸牢中华民族共同体意识,为在法治... 详细信息

法学教育应当坚决贯彻铸牢中华民族共同体意识的主线地位,也可成为铸牢中华民族共同体意识的重要实践路径。新时代法学教育需要服务于国家铸牢中华民族共同体意识、依法治理民族事务大局,引导法科学生铸牢中华民族共同体意识,为在法治实践中加强中华民族共同体建设奠定法治人才基础。法治国家建设与铸牢中华民族共同体意识在价值层面存在高度契合,这为法学教育具有作为铸牢中华民族共同体意识的实践路径提供了宏观可能。在法学教育作为铸牢中华民族共同体意识实践路径的具体操作层面,可以以课程思政为载体,将铸牢中华民族共同体意识贯彻到法学教育和法治人才培养体系全过程,重点从把握好课程思政参与主体的二元性、在课程设置和授课内容中充分贯彻铸牢中华民族共同体意识的主线地位、在实践教学中践行中华民族共同体意识三个方面着力。

关键词：铸牢中华民族共同体意识依法治理民族事务法学教育课程思政

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