检索结果-南通市图书馆

Machine learning insights concerning inflammatory and liver-related risk comorbidities in non-communicable and viral diseases

引用

World journal of Gastroenterology 2022年第44期28卷 6230-6248页

作者： j.alfredo martínez marta Alonso-Bernáldez Diego martínez-Urbistondo juan A Vargas-Nuñez Ana Ramírezde Molina Alberto Dávalos Omar Ramos-Lopez Precision Nutrition and Cardiometabolic Health Madrid Institute of Advanced Studies-Food InstituteMadrid 28049Spain Department of Internal Medicine Hospital Universitario HM SanchinarroMadrid 28050Spain Servicio de Medicina Interna Hospital Universitario Puerta de Hierro MajadahondaMadrid 28222MajadahondaSpain Molecular Oncology and Nutritional Genomics of Cancer Madrid Institute of Advanced Studies-Food InstituteMadrid 28049Spain Laboratory of Epigenetics of Lipid Metabolism Madrid Institute of Advanced Studies-Food InstituteMadrid 28049Spain Medicine and Psychology School Autonomous University of Baja CaliforniaTijuana 22390Baja CaliforniaMexico

The liver is a key organ involved in a wide range of functions,whose damage can lead to chronic liver disease(CLD).CLD accounts for more than two million deaths worldwide,becoming a social and economic burden for most *** the different factors that can cause CLD,alcohol abuse,viruses,drug treatments,and unhealthy dietary patterns top the *** conditions prompt and perpetuate an inflammatory environment and oxidative stress imbalance that favor the development of hepatic *** stages of fibrosis can eventually lead to cirrhosis or hepatocellular carcinoma(HCC).Despite the advances achieved in this field,new approaches are needed for the prevention,diagnosis,treatment,and prognosis of *** this context,the scientific community is using machine learning(ML)algorithms to integrate and process vast amounts of data with unprecedented *** techniques allow the integration of anthropometric,genetic,clinical,biochemical,dietary,lifestyle and omics data,giving new insights to tackle CLD and bringing personalized medicine a step *** review summarizes the investigations where ML techniques have been applied to study new approaches that could be used in inflammatoryrelated,hepatitis viruses-induced,and coronavirus disease 2019-induced liver damage and enlighten the factors involved in CLD development.

关键词： Machine learning Liver inflammation Liver disease Viral diseases Comorbidity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anemia in inflammatory bowel disease: A neglected issue with relevant effects

引用

World journal of Gastroenterology 2014年第13期20卷 3542-3551页

作者： Danila Guagnozzi alfredo j Lucendo Department of Gastroenterology Hospital General de Tomelloso 13700 TomellosoCiudad RealSpain

Anemia, a common complication associated with inflammatory bowel disease (IBD), is frequently overlooked in the management of IBD patients. Unfortunately, it represents one of the major causes of both decreased quality of life and increased hospital admissions among this population. Anemia in IBD is pathogenically complex, with several factors contributing to its development. While iron deficiency is the most common cause, vitamin B12 and folic acid deficiencies, along with the effects of pro-inflammatory cytokines, hemolysis, drug therapies, and myelosuppression, have also been identified as the underlying etiology in a number of patients. Each of these etiological factors thus needs to be identified and corrected in order to effectively manage anemia in IBD. Because the diagnosis of anemia in IBD often presents a challenge, combinations of several hematimetric and biochemical parameters should be used. Recent studies underscore the importance of determining the ferritin index and hepcidin levels in order to distinguish between iron deficiency anemia, anemia due to chronic disease, or mixed anemia in IBD patients. With regard to treatment, the newly introduced intravenous iron formulations have several advantages over orally-administered iron compounds in treating iron deficiency in IBD. In special situations, erythropoietin supplementation and biological therapies should be considered. In conclusion, the management of anemia is a complex aspect of treating IBD patients, one that significantly influences the prognosis of the disease. As a consequence, its correction should be considered a specific, first-line therapeutic goal in the management of these patients.

关键词： Anemia Inflammatory bowel disease Iron deficiency Anemia of chronic disease Erythropoietin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ligand effects on the structure and vibrational properties of the thiolated Au18 cluster

引用

Progress in Natural Science:Materials International 2016年第5期26卷 510-515页

作者： alfredo Tlahuice-Flores CICFIM-Facultad de Ciencias Físico-Matemáticas Universidad Autónoma de Nuevo León

Most of the studies devoted to thiolated gold clusters suppose that their core and Au-S framework do not suffer from distortion independently of the protecting ligands（-SR） and it is assumed as correct to simplify the ligand as SCH3. In this work is delivered a systematic study of the structure and vibrational properties（IR and Raman）of the Au18（SR）14cluster. The pursued goal is to understand the dependency of the displayed vibrational properties of the thiolated Au18cluster with the ligands type. A set of six ligands was considered during calculations of the vibrational properties based on density functional theory（DFT） and in its dispersioncorrected approach（DFT-D）.

关键词： Gold cluster Ligand effects Structure Vibration Au18(SR)14 Density functional theory

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Complementarity of electric vehicles and pumped-hydro as energy storage in small isolated energy systems:case of La Palma,Canary Islands

引用

journal of Modern Power Systems and Clean Energy 2016年第4期4卷 604-614页

作者： alfredo RAMIREZ-DIAZ Francisco j.RAMOS-REAL Gustavo A.MARRERO Departamento de Economı´a Contabilidad y FinanzasFacultad de Economı´aEmpresa y TurismoUniversidad de La Laguna38071 La LagunaSpain Instituto Universitario de Ciencias Polı´ticas y Sociales Universidad de La Laguna38071 La LagunaSpain Instituto Universitario de Desarrollo Regional Universidad de La Laguna38071 La LagunaSpain

Isolated energy systems in archipelagos are characterized for having a great dependence on fossil sources due to isolation and territorial *** island of La Palma is situated on the northwest of the Canary Islands,and its electric system is very *** policies planned by local authorities are aimed to increase the share of renewable energies and the reduction of fossil ***,intermittence and the concentration of unmanageable renewable energies in few locations may hinder the operation of the *** order to solve these problems,energy storage plays an essential *** aim of this paper is to analyse the effects of the introduction of two possible alternatives as a way of energy storage:pumped hydro storage and electric *** this,we use a simulation model adapted to the features of La Palma,considering different *** show that,in the most favourable scenario,the installation of an additional 25 MW from renewables(more than double the current power),supported by 20 MW of pumped hydro storage and a fleet of 3361 electric vehicles,would allow the current share of renewables to increase from11%(in 2015)to 49%.Furthermore,this would mean a 26%reduction in CO2 emissions,10%in costs of generated k Wh and 19%in energy dependence.

关键词： Energy storage Electric vehicles Vehicle-to-grid Grid-for-vehicles Pumped-hydro energy storage Isolated systems

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Threat recognition and response in an avian brood-parasite host from New Caledonia

引用

Current Zoology 2021年第3期67卷 255-262页

作者： alfredo Attisaino Kasper Hlebowicz Roman Gula jorn Theuerkauf Museum and Institute of Zoology Polish Academy of SciencesWarsawPoland Conservation Research New Caledonia La FoaNew Caledonia

Nest predation and avian brood parasitism are the main sources of nest failure in many passerine *** predators threaten both brood and parents,whereas brood parasites pose only a danger to eggs or *** fan-tailed gerygone Gerygone flavolateralis from New Caledonia is subjected to high rates of nest predation by the New Caledonian crow Corvus moneduloides(responsible for about 20-40%of predation)and moderate rates of brood parasitism by the shining bronze-cuckoo Chalcites lucidus(parasitizing about 18%of nests),which also depredates nests that are too advanced for parasitism(13%of nests).To test if fan-tailed gerygones are able to discriminate predators from brood parasites,we presented 3 bird models at active gerygone nests:a brood parasite/small nest predator(shining bronze-cuckoo),a large nest predator(crow),and a small non-native bird(common chaffinch Fringilla coelebs),which is unknown to the gerygone,as a *** assessed the response of adult gerygones to the presentation of each model by measuring the minimum approach distance,number of alarm calls,number of attacks,and time to first nest visit after the presentation(latency).Adult gerygones often attacked the cuckoo,approached but never attacked the chaffinch and always avoided the *** was shorter after an attack response and during brooding,but similar among *** did not find any link between the cuckoo model presentation and later ejection of cuckoo *** conclude that adult fan-tailed gerygones discriminate between different models and respond accordingly to the level of threat but do not show awareness of parasitism risk and increase of nestling ejection rates following exposure to the cuckoo model.

关键词： brood parasitism enemy recognition frontline defense mobbing nest defense nest predation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light Front Boson Model Propagation

引用

Communications in Theoretical Physics 2011年第6期55卷 1029-1040页

作者： jorge Henrique Sales alfredo Takashi Suzuki Universidade Estadual de Santa Cruz km 16 Rodovia Ilheus-Itabuna-45662-900-IlheusBABrazil Instituto de Fisica Teorica UNESP-Universidade Estadual PaulistaRua Dr.Bento Teobaldo Ferraz 271-Bl.ⅡBarra Funda01140-070Sao PauloSao PauloBrazil

The scope and aim of this work is to describe the two-body interaction mediated by a particle （either the scalar or the gauge boson） within the light-front formulation. To do this, first of all we point out the importance of propagators and Green functions in Quantum Mechanics. Then we project the covariant quantum propagator onto the light front time to get the propagator for scalar particles in these coordinates. This operator propagates the wave function from x＋ = 0 to x＋〉 0. It corresponds to the definition of the time ordering operation in the light front time x＋. We calculate the light-front Green＇s function for 2 interacting bosons propagating forward in x＋. We also show how to write down the light front Green＇s function from the Feynman propagator and finally make a generalization to N bosons.

关键词： insert light-front bosons propagation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Light Front Fermion Model Propagation

引用

Communications in Theoretical Physics 2013年第7期60卷 55-68页

作者： jorge Henrique Sales alfredo Takashi Suzukil Universidade Estadual de Santa Cruz km 16 Rodovia Jorge Amado-45662-900-Ilhéus BA Brazi Physics and Engineering Department Southern Adventist University 4881 Taylor Circle-Collegedale TN 37315 USA Instituto de Física Terica UNESP-Universidade Estadual Paulista Rua Dr. Bento Teobaldo Ferraz 271-Bloco II Barra Funda 01140-070 So Paulo So Paulo Brazil

In this work we consider the propagation of two fermion fields interacting with each other by the exchange of intermediate scalar bosons in the light front. We obtain the corrections up to fourth order in the coupling... 详细信息

关键词： light front Fermions propagations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A perceptual quality metric for 3D triangle meshes based on spatial pooling

引用

Frontiers of Computer Science 2018年第4期12卷 798-812页

作者： Xiang FENG Wanggen WAN Richard Yi Da XU Haoyu CHEN Pengfei LI j. alfredo SANCHEZ School of Communication and Information Engineering Shanghai University Shanghai 200444 China Faculty of Engineering and Information Technology University of Technology Sydney Sydney NSW 2007 Australia Institute of Smart City Shanghai University Shanghai 200444 China Department of Computing Electronics and Mechatronics Universidad de las Americas Puebla (UDLAP) Cholula 72820 Mexico

In computer graphics, various processing operations are applied to 3D triangle meshes and these processes often involve distortions, which affect the visual quality of surface geometry. In this context, perceptual quality assessment of 3D triangle meshes has become a crucial issue. In this paper, we propose a new objective quality metric for assessing the visual difference between a reference mesh and a corresponding distorted mesh. Our analysis indicates that the overall quality of a distorted mesh is sensitive to the distortion distribution. The proposed metric is based on a spatial pooling strategy and statistical descriptors of the dis- tortion distribution. We generate a perceptual distortion map for vertices in the reference mesh while taking into account the visual masking effect of the human visual system. The proposed metric extracts statistical descriptors from the dis- tortion map as the feature vector to represent the overall mesh quality. With the feature vector as input, we adopt a support vector regression model to predict the mesh quality score. We validate the performance of our method with three publicly available databases, and the comparison with state-of-the-art metrics demonstrates the superiority of our method. Experimental results show that our proposed method achieves a high correlation between objective assessment and subjective scores.

关键词： mesh visual quality assessment spatial pooling statistical descriptors support vector regression visual masking

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The effect of FER zeolite acid sites in methanol-to-dimethyl-ether catalytic dehydration

引用

journal of Energy Chemistry 2017年第3期26卷 406-415页

作者： Enrico Catizzone alfredo Aloise Massimo Migliori Girolamo Giordano Department of Environmental and Chemical Engineering University of CalabriaVia P.BucciCubo 42aI-87036 RendeCSItaly

In this paper, the effect of acidity of zeolites with FER framework was studied in the methanol dehydration to dimethyl ether reaction, by comparing catalysts with different Si/Al ratios(namely 8, 30 and60). The aim of this work was to investigate how the acid sites concentration, strength, distribution and typology(Br?nsted and Lewis) affect methanol conversion, DME selectivity and coke formation. It was found that the aluminium content affects slightly acid sites strength whilst a relevant effect on acid sites concentration and distribution(Br?nsted/Lewis) was observed as 24% of Lewis sites were found on Alrichest samples, whilst less than 10% of Lewis acid sites were observed on FER at higher Si/Al ratio. All the investigated catalyst samples showed a selectivity toward DME always greater than 0.9 and samples with the lowest Si/Al ratio exhibit the best performances in terms of methanol conversion, approaching the theoretical equilibrium value(around 0.85) at temperatures below 200 °C. Turnover-frequency analysis suggests that this result seems to be related not only to the higher amount of acid sites but also that the presence of Lewis acid sites may play a significant role in converting methanol. On the other hand, the presence of Lewis acid sites, combined with a high acidity, promote the formation of by-products(mainly methane) and coke deposition during the reaction. As final evidence, all the investigated catalysts exhibit very high resistance to deactivation by coke deposition, over 60 h continuous test, and a GC–MS analysis of the coke deposited on the catalyst surface reveals tetra-methyl benzene as main component.

关键词： Methanol dehydration Dimethyl ether Lewis acid sites FER zeolite Coke formation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of liver enzymes on SARS-CoV-2 infection and the severity of clinical course of COVID-19

引用

Liver Research 2021年第1期5卷 21-27页

作者： Fátima Higuera-de la Tijera alfredo Servín-Caamaño Daniel Reyes-Herrera Argelia Flores-López Enrique j.A.Robiou-Vivero Felipe martínez-Rivera Victor Galindo-Hernández Oscar Chapa-Azuela Alfonso Chávez-Morales Victor H.Rosales-Salyano Multidisciplinary Team for the Attention and Care of Patients with COVID-19 Hospital General de México Dr.Eduardo LiceagaMexico CityMexico Gastroenterology and Hepatology Department Hospital General de México Dr.Eduardo LiceagaMexico CityMexico Internal Medicine Department Hospital General de México Dr.Eduardo LiceagaMexico CityMexico Hepatobiliary and Pancreatology Clinic Surgery DepartmentHospital General de México Dr.Eduardo LiceagaMexico CityMexico Intensive Care Unit Hospital General de México Dr.Eduardo LiceagaMexico CityMexico

Background and aim Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the virus responsible for the current pandemic,can have multi-organ *** studies show that liver injury could be a manifestation of the disease,and that liver disease could also be related to a worse *** aim was to compare the characteristics of patients with severe coronavirus disease 2019(COVID-19)due to SARS-CoV-2 who required intubation versus stable hospitalized patients to identify the early biochemical predictive factors of a severe course of COVID-19 and subsequent requirement for intubation,specifically in *** This was an observational case-control study nested in a cohort *** medical records of patients admitted for confirmed COVID-19 at a tertiary level center in Mexico City were *** and biochemical data were collected,and the characteristics of patients who required invasive mechanical ventilation(IMV)(cases)were compared with stable hospitalized patients without ventilation(controls).Results We evaluated 166 patients with COVID-19 due to SARS-CoV-2 infection;114(68.7%)were men,the mean age was 50.6±13.3 years,and 27(16.3%)required *** comparative analysis between cases and controls showed(respectively)significantly lower blood oxygen saturation(SpO_(2))(73.5±12.0%vs.83.0±6.8%,P<0.0001)and elevated alanine aminotransferase(ALT)(128(14–1123)IU/L vs.33(8–453)IU/L,P=0.003),aspartate aminotransferase(AST)(214(17–1247)vs.44(12–498)IU/L,P=0.001),lactic dehydrogenase(LDH)(764.6±401.9 IU/L vs.461.0±185.6 IU/L,P=0.001),and D-dimer(3463(524–34,227)ng/mL vs.829(152–41,923)ng/mL,P=0.003)*** in the cases group were older(58.6±12.7 years vs.49.1±12.8 years,P=0.001).Multivariate analysis showed that important factors at admission predicting the requirement for IMV during hospitalization for COVID-19 were AST≥250 IU/L(odds ratio(OR)=64.8,95%confidence interval(CI)7.5–560.3,P<0.0001)and D-dimer≥3500 ng/mL(OR=4.1,95

关键词： Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Coronavirus disease 2019(COVID-19) Liver enzymes D-dimer Disease severity Invasive mechanical ventilation(IMV) Multi-organ failure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：