检索结果-南通市图书馆

Ground-state mass of ^(22)Al and test of state-of-the-art ab initio calculations

Chinese Phy.ics C 2024年第3期48卷 72-78页

作者：孙铭泽于越王新鹏王猛李健国张玉虎 K.Blaum 陈祖毅陈瑞九邓涵宇付超义葛文文黄文嘉焦红扬李红蕙李宏福罗胤芳廖挺 y.ALitvinov 司敏帅鹏史金阳王茜邢元明徐星徐瑚珊许甫荣袁琪 T.y.maguchi 颜鑫亮杨建成原有进周小红周旭张敏曾奇 CAS Key.Laboratory.of High Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Max-Planck-Institut für Kernphy.ik Saupfercheckweg 169117 HeidelbergGermany GSI Helmholtzzentrum für Schwerionenforschung Planckstraße 164291 DarmstadtGermany Advanced Energy.Science and Technology.Guangdong Laboratory Huizhou516007China State Key.Laboratory.of Nuclear Phy.ics and Technology School of PhysicsPeking UniversityBeijing 100871China Department of Phy.ics Saitama UniversitySaitama 338-8570Japan School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China

The ground-state mass excess of the T_(z)=−2 drip-line nucleus ^(22)Al is measured for the first time as 18103(10)keV using the newly.developed Bρ-defined isochronous mass spectrometry.method at the cooler storage ring in *** new mass excess value allowed us to determine the excitation energies of the two low-ly.ng 1+states in ^(22)Al with significantly.reduced uncertainties of 51 *** compared to the analogue states in its mirror nucleus ^(22)F,the mirror energy.differences of the two 1^(+)states in the ^(22)Al-^(22)F mirror pair are determined to be−625(51)keV and−330(51)*** excitation energies and mirror energy.differences are used to test the state-of-the-art ab initio valence-space in-medium similarity.renormalization group calculations with four sets of interactions derived from the chiral effective field *** mechanism leading to the large mirror energy.differences is investigated and attributed to the occupation of theπs_(1/2) orbital.

关键词： nuclear mass Bρ-defined IMS mirror energy.difference ab initio VS-IMSRG calculations chiral interactions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laboratory.evaluation of toxicity.of selected insecticides against egg and larval stages of cotton pink bollworm, Pectinophora gossy.iella (Saunders) (Lepidoptera: Gelechiidae)

引用

journal of Cotton Research 2024年第1期7卷 15-28页

作者： BUSNOOR Abhishek V. WADASKAR R.M. FAND Babasaheb B. TAMBE V.j. PILLAI T. MAHULE D.j. NAGRARE V.S. PRASAD y.G. Entomology.Section College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia Indian Council of Agricultural Research-Central Institute for Cotton Research Nagpur 441108MaharashtraIndia

Background The cry.tic nature of pink bollworm Pectinophora gossy.iella(Saunders)larvae enables its reduced vul-nerability.to insecticidal ***,the development of resistance against Bacillus thuringiensis(Bt)toxins posed a serious threat to transgenic cotton *** necessitated determining the critical timing of spray.applications on the control *** study.assessed the influence of egg age(freshly.laid ***-day.old)and the loca-tion of larvae(directly.exposed to the insecticide residues on the boll rind *** inside the bolls)on insecticide control *** The results revealed a significant decrease in the ovicidal activity.of tested insecticides with an increase in the age of eggs from one day.old to three day. old(paired t-test,Py.exposed to the insec-ticide residues on the boll rind were more susceptible(>80%mortality.than the larvae exposed after they.had bur-rowed inside the bolls(y..The inhibitory.effects of tested insecticides on developmental biology.were more pronounced in the experiment on pre-larval release insecticide treatment compared with insecticide treatment given post-larval release and entry.inside the *** Egg age influences the insecticide susceptibility.as does the larval location,directly.exposed vs bur-rowed inside the *** eggs and the larvae that had burrowed inside the green bolls of cotton were relatively.less susceptible to the insecticide *** toxic effects of insecticides on egg and larval stages were primar-ily.*** findings are significant for devising a comprehensive strategy.for pink bollworm management on a sustainable basis.

关键词： Bioefficacy Cotton Insecticides Pink bollworm Pectinophora gossy.iella Timings of spray

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Engineering hy.luronic acid-based nanoassemblies for monoclonal antibody.delivery.design,characterization,and biological insights

引用

Nano Research 2024年第10期17卷 9111-9125页

作者： Ana M.López-Estévez y.Zhang María Medel Iker Arriaga Lucía Sanjurjo Cristian Huck-Iriart Nicola G.A.Abrescia María j.Vicent Defang Ouy.ng Dolores Torres María josé Alonso Center for Research in Molecular Medicine and Chronic Diseases(CiMUS) University of Santiago de CompostelaSantiago de Compostela 15782Spain Department of Pharmacology Pharmacy and Pharmaceutical TechnologySchool of PharmacyUniversity of Santiago de CompostelaSantiago de Compostela 15782Spain Health Research Institute of Santiago de Compostela(IDIS) Santiago de Compostela 15782Spain State Key.Laboratory.of Quality.Research in Chinese Medicine Institute of Chinese Medical Sciences(ICMS)University of MacaoMacao 999078China Poly.er Therapeutics Laboratory.and CIBERONC Prince Felipe Research Centre Valencia E-46012Spain Structure and Cell Biology.of Viruses Lab CIC bioGUNEBasque Research and Technology Alliance(BRTA)Derio 48160Spain ALBA Sy.chrotron Light Source Experiments DivisionCerdanyola del VallèsBarcelona 08290Spain IKERBASQUE Basque Foundation for ScienceBilbao 48009Spain

The current spotlight of cancer therapeutics is shifting towards personalized medicine with the widespread use of monoclonal antibodies(mAbs).Despite their increasing potential,mAbs have an intrinsic limitation related to their inability.to cross cell membranes and reach intracellular *** offers promising solutions to overcome this limitation,however,formulation challenges *** challenges are the limited loading capacity.often insufficient to achieve clinical dosing),the complex formulation methods,and the insufficient characterization of mAb-loaded ***,we present a new nanocarrier consisting of hy.luronic acid-based nanoassemblies(HANAs)specifically.designed to entrap mAbs with a high efficiency.and an outstanding loading capacity.50%,w/w).HANAs composed by.an mAb,modified HA and phosphatidy.choline(PC)resulted in sizes of~100 nm and neutral surface *** modeling identified the principal factors governing the high affinity.of mAbs with the amphiphilic HA and *** composition and structural configuration were analy.ed using the orthogonal techniques cry.genic transmission electron microscopy.cry.-TEM),asy.metrical flow field-flow fractionation(AF4),and small-angle X-ray.scattering(SAXS).These techniques provided evidence of the formation of core-shell nanostructures comprising an aqueous core surrounded by.a bilay.r consisting of phospholipids and amphiphilic *** vitro experiments in cancer cell lines and macrophages confirmed HANAs’low toxicity.and ability.to transport mAbs to the intracellular *** reproducibility.of this assembling process at industrial-scale batch sizes and the long-term stability.was *** conclusion,these results underscore the suitability.of HANAs technology.to load and deliver biologicals,which holds promise for future clinical translation.

关键词： monoclonal antibody nanoparticles hy.luronic acid characterization particle size computational modeling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

应变率对3D打印混凝土抗压性能的影响

引用

硅酸盐学报 2024年第5期52卷 1499-1507页

作者：王海龙陶傲孙晓燕浙江大学建筑工程学院杭州310058 山西浙大新材料与化工研究院太原030002 浙江大学平衡建筑研究中心杭州310028 灵砼科技(杭州)有限公司杭州310058

为评价应变率对3D打印混凝土动态抗压性能的影响,开展4种应变率下打印混凝土3个正交方向的单轴压缩试验,得到不同加载工况下3D打印混凝土的受压破坏形态和应力-应变曲线,探讨了应变率和不同方向对3D打印混凝土抗压强度、弹性模量、峰值... 详细信息

为评价应变率对3D打印混凝土动态抗压性能的影响,开展4种应变率下打印混凝土3个正交方向的单轴压缩试验,得到不同加载工况下3D打印混凝土的受压破坏形态和应力-应变曲线,探讨了应变率和不同方向对3D打印混凝土抗压强度、弹性模量、峰值应变及各向异性的影响规律,考虑应变率效应提出3D打印混凝土各个方向动态抗压强度与动态弹性模量的经验计算公式。研究结果表明:3D打印混凝土裂缝萌生于层条间薄弱界面处并沿界面扩展,这些发展于薄弱界面处的裂缝决定了3D打印混凝土的破坏失效;各个方向的动态峰值应力和动态弹性模量均存在一定程度的应变率相关性,y.向抗压强度率相关性最高;3D打印混凝土的各向异性随着应变率增加而减小,在高应变率下变化幅度很小。

关键词： 3D打印混凝土应变率力学性能各向异性率效应

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

INVESTIGATION ON HOT DUCTILITy.AND STRENGTH OF CONTINUOUS CASTING SLAB FOR AH32 STEEL

引用

Acta Metallurgica Sinica(English Letters) 2006年第1期19卷 75-78页

作者： G. y. Li X.F. Li L.G. ao Technology.Center Anshan Iron and Steel Group CorporationAnshan 114009 China

By.means of Gleeble-1500 testing machine, the simulation of continuous casting process forAH32 steel was carried out and hot ductility.and strength were determined. The cracking sensitivity.was studied under the different temperatures and strain rates. The Precipitations of AIN at different temperatures and the fractures of high-temperature tensile samples were observed by.using TEM （transmission electron microscope） and SEM （scanning electron microscope）. The factors affecting the brittle temperature zone were discussed.

关键词： continuous casting slab brittle temperature zone tensile strength,ductility simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sy.thesis of coral-like structures of Pr-y. co-doped y.G: Structural,optical, magnetic and antimicrobial properties

引用

journal of Rare Earths 2024年第3期42卷 543-554,I0004页

作者： A.Fernandez Francisca P.Araujo y.Guerra S.Castro-Lopes j.Matilla-Arias Idglan S.de Lima Edson C.Silva-Filho josy.A.Osajima F.Guerrero R.Pena-Garcia Federal University.of Piau Graduate Program in Materials Science and EngineeringTeresinaPIBrazil Federal Rural University.of Pernambuco Academic Unit of Cabo de Santo AgostinhoCabo de Santo AgostinhoPEBrazil Federal University.of Piaui Department of PhysicTeresinaPBrazil Federal University.of Pernambuco Graduate Program in Materials ScienceRecifePEBrazil University.of Granma Departmentof Basic Sciences and Applied InformaticsFaculty of Technical SciencesBayamoCuba Federal University.of Amazonas Department of PhysicManausAMBrazil Federal University.of Pernambuco Department of PhysicRecifePEBrazil

Coral-like structures of the y.(3-x)Pr_(x)Fe_(5-y.y._(y.O_(12),(0.00 ≤ x ≤ 0.04, 0.00 ≤ y.≤ 0.02) compound were sy.thesized using the sol-gel method. Structural investigation certified the y.G cubic cry.tal structure formation, without any.secondary.phase. It is shown that, the relatively.large ionic radius of the dopant cations results in an expansion of the lattice parameter, variations in the Iona-O-Iondangle, Iona-O,Iond-O and Ionc-O bond distances and decrease in the average cry.tallite size. Fourier transform infrared(FTIR) and Raman measurements are essential to testify.the single-phase formation of y.G cry.tal structure and are observed changes in the stretching and vibrational modes, respectively. The morphological study. energy.dispersive spectroscopy.EDS) spectra and textural properties show corallike structures, peaks associated with Pr^(3+) and y.^(3+) atoms and the effect of dopants on surface area,diameter, and pore volume, respectively. The optical analy.is from diffuse reflectance spectra witnessed an increase in the optical gap band, a decrease in Urbach energy.and blue shift in the charge transfer,correlated with the expansion of the unit cell due to the dopant's insertion in the y.G structure. A ty.ical ferrimagnetic behavior is exhibited by.the y.(3-x)Pr_(x)Fe_(5-y.y._(y.O_(12)compound. The saturation magnetization(M_(s)), cubic anisotropy.constant(K_(1)) and coercive field(H_(c)) increase with the Pr^(3+)cations content, as consequence of their magnetic nature and distribution around of Fe^(3+)ions due to the coexistence with the y.^(3+). Finally. for the first time, antibacterial tests by.mean of the direct contact method were performed for y.G co-doped with Pr^(3+)and y.^(3+)and it is shown that, relatively.high dosages of Pr^(3+) cations favored the activity.against S. aureus, therefore, a new biological property.for y.G doped with rare earths is presented.

关键词： y.trium iron garnet(y.G) Coral-like structures Rare earths Band gap energy Magnetic properties Antimicrobial properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Blood Pressure Profile and Gly.emic Control of Ty.e 2 Diabetics and Hy.ertensives at the y.lgado Ouedraogo University.Hospital: A Review of 116 Cases

引用

World journal of Cardiovascular Diseases 2024年第1期14卷 61-76页

作者： G. R. C. Millogo A. Thiam y. Kambiré E. Nongkouni S. E. Dabiré L. j. Kagambéga j. K. Kologo V. N. y.méogo P. Zabsonré Department of Cardiology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Department of Cardiology Tengandogo University Hospital Ouagadougou Burkina Faso

Objective: The association hy.ertension and diabetes is important. The two pathologies may.influence each other. The aim was to study.the correlation between gly.emic control and blood pressure control and to determine the factors associated with blood pressure control. Methodology. This was a descriptive cross-sectional study.with an analy.ical focus over 7 months. Patients were recruited as outpatients and all underwent ambulatory.blood pressure measure, gly.ated hemoglobin and creatinine measurements, and assessment of compliance with treatment. Results: During this period 116 patients were collected. The predominance was female 69%. The mean age of the patients was 62 ± 7 y.ars with a peak between 60 and 70 y.ars. The average age of hy.ertension was 12 y.ars and that of diabetes 6 1/2 y.ars. The most frequently.associated cardiovascular risk factor was a sedentary.lifesty.e (71.5%) after age. 57.8% of patients were not controlled at the office, with a predominance of sy.tolic hy.ertension (58.2%). 61.6% of patients were controlled by.ambulatory.blood pressure measure, a rate of 47.8% of white coat hy.ertension. Gly.emic control was observed in 42.2% of cases and 87% of patients had good renal function (glomerular filter rate ≥ 60 ml/mn). Therapeutic compliance was good in 53.4% of cases and dual therapy.was the most used therapeutic modality.44.8% (52 patients) followed by.triple therapy. The factors associated with poor blood pressure control were gly.emic imbalance, non-compliance and monotherapy. Dual therapy.had a protective effect. Conclusion: The association of hy.ertension and ty.e 2 diabetes is frequent. The risk of occurrence increases with age. Ambulatory.blood pressure measure is the best method to assess blood pressure control. Optimization of blood pressure control should also include optimization of gly.emic control.

关键词： Blood Pressure Control Gly.emic Control Hy.ertensive and Diabetic Patients

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

HI in High Gas-phase Metallicity.Dwarf Galaxy.WISEA j230615.06+143927.9

引用

Research in Astronomy.and Astrophy.ics 2024年第1期24卷 292-299页

作者： y.n Guo C.Sengupta T.C.Scott P.Lagos y.Luo Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy.and Space Sciences University of Science and Technology of ChinaHefei 230026China Institute of Astrophy.ics and Space Sciences(IA Porto) Rua das Estrelas4150-762PortoPortugal

We present resolved Giant Metrewave Radio Telescope H I observations of the high gas-phase metallicity.dwarf galaxy.WISEA j230615.06+143927.9(z = 0.005)(hereafter j2306) and investigate whether it could be a Tidal Dwarf Galaxy.TDG) candidate. TDGs are observed to have higher metallicities than normal dwarfs. j2306 has an unusual combination of a blue g-r color of 0.23 mag, irregular optical morphology.and high-metallicity.12 +log(O/H) = 8.68 ± 0.14), making it an interesting galaxy.to study.in more detail. We find j2306 to be an H I rich galaxy.with a large extended, unperturbed rotating H I disk. Using our H I data we estimated its dy.amical mass and found the galaxy.to be dark matter(DM) dominated within its H I radius. The quantity.of DM, inferred from its dy.amical mass, appears to rule out j2306 as an evolved TDG. A wide area environment search reveals j2306 to be isolated from any.larger galaxies which could have been the source of its high gas metallicity. Additionally. the H I morphology.and kinematics of the galaxy.show no indication of a recent merger to explain the *** detailed optical spectroscopic observations of j2306 might provide an answer to how a seemingly.ordinary.irregular dwarf galaxy.achieved such a high level of metal enrichment.

关键词： galaxies:abundances galaxies:dwarf galaxies:irregular radio lines:galaxies radio lines:ISM

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Amplitude analy.is of the decay. D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

引用

Chinese Phy.ics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An y.Bai O.Bakina I.Balossino y.Ban H.-R.Bao V.Batozskay. K.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boy.o R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin j.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.L.Chen S.j.Chen S.L.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen y.B.Chen y.Q.Chen Z.j.Chen Z.y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio j.j.Cui H.L.Dai j.P.Dai A.Dbey.si R.E.de Boer D.Dedovich C.Q.Deng Z.y.Deng A.Denig I.Deny.enko M.Destefanis F.De Mori B.Fang S.S.Fang W.X.Fang y.Fang y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng j.H.Feng y.T.Feng K.Fischer M.Fritsch C.D.Fu j.L.Fu y.W.Fu H.Gao y.N.Gao y.ng Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.M.Gersabeck B.Ding X.X.Ding y.Ding y.Ding j.Dong L.y.Dong M.y.Dong X.Dong M.C.Du S.X.Du Z.H.Duan P.Egorov y.H.Fan j.Fang jA.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu y.T.Gu C.y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.j.Guo R.P.Guo y.P.Guo A.Guskov j.Gutierrez K.L.Han T.T.Han X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz y.K.Heng C.Herold T.Holtmann P.C.Hong G.y.Hou X.T.Hou y.R.Hou Z.L.Hou B.y.Hu H.M.Hu j.F.Hu T.Hu y.Hu G.S.Huang K.X.Huang L.Q.Huang X.T.Huang y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad j.jackson S.janchiv j.H.jeong Q.ji Q.P.ji W.ji X.B.ji X.L.ji y.y.ji X.Q.jia Z.K.jia D.jiang H.B.jiang P.C.jiang S.S.jiang T.j.jiang X.S.jiang y.jiang j.B.j.ao j.K.j.ao Z.j.ao S.jin y.jin M.Q.jing X.M.jing T.johansson S.Kabana N.Kalantar-Nay.stanaki X.L.Kang X.S.Kang M.Kavatsy.k B.C.Ke V.Khachatry.n A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf M.Kuessner X.Kui A.Kupsc W.K\"uhn j.j.Lane P.Larin L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff M.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.M.Li F.Li G.Li H.Li H.B.Li H.j.Li H.N.Li Hui Li j.R.Li j.S.Li K.Li L.j.Li L.K.Li Lei Li M.H.Li P.R.Li Q.M.Li Q.X.Li R.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.y.Li y Institute of High Energy.Phy.ics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Phy.ics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University.of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University.Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy.Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University.of Science and Technology Luoyang 471003China Henan University.of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology.Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Phy.ics Lanzhou 730000China Institute of Phy.ics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity.of 2.93 fb^(−1)taken at the center-of-mass energy.s=3.773 GeV with the BESIII detector,a joint amplitude analy.is is performed on the decay. D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decay. D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(sy.t.))%and(68.9±1.5_(stat).±2.4_(sy.t.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(sy.t.))%and(0.951±0.025_(stat.)±0.021_(sy.t.))%,*** amplitude analy.is provides an important model for the binning strategy.in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decay. amplitude analy.is CP-even fraction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particle elasticity.influences poly.eric artificial antigen presenting cell effectiveness in vivo via CD8+T cell activation,macrophage uptake,and the protein corona

引用

Nano Research 2024年第10期17卷 9052-9064页

作者： Savannah E.Est-Witte Sy.ney.R.Shannon Dennis H.Gong Kaitly. G.Calabresi jawaun j.Harris Kaitly. Storm Edwin j.y.o Ariel Isser Vivek P.jani Natalie K.Livingston Mary.O.Omotoso Kelly.Rhodes Elana Ben-Akiva Randall A.Mey.r Zoe T.Hsieh Simone Sidoli Stephany.y.Tzeng jonathan P.Schneck jordan j.Green Translational Tissue Engineering Center Institute for NanobiotechnologyDepartment of Biomedical EngineeringJohns Hopkins School of Medicine400 N BroadwayBaltimoreMD 21231USA Institute for Cell Engineering Department of PathologyJohns Hopkins School of Medicine733 N BroadwayBaltimoreMD 21205USA Department of Biochemistry Albert Einstein College of MedicineThe BronxNew York CityNY 10461USA

Adoptive cell therapy.ACT)is an immunotherapy.strategy.for cancer that has seen widespread clinical *** ACT,patient-derived ly.phocy.es are stimulated with the antigen of interest ex vivo,proliferated,then returned to the patient to initiate an antigen-specific antitumor *** effective,this process is resource-intensive and logistically.impossible for many.*** artificial antigen presenting cells(aAPCs)offer a potential“off-the-shelf”alternative to ex vivo *** particulate aAPCs perform well in vitro,they.have had limited success in vivo due to poor bioavailability.after *** to bioavailability.include rapid clearance,unfavorable biodistribution,and inadequate interactions with CD8+T cells at sites of *** properties such as elasticity.have been shown to vastly.impact the bioavailability.and particle-cell interactions,but this has y.t to be investigated in the context of aAPCs for in vivo T-cell *** literature likewise indicates that biomaterial properties,especially.elasticity.can modulate T-cell activation in *** the goal of creating a more biomimetic,next-generation particulate aAPC,we developed a poly.ethy.ene)gly.ol hy.rogel particle platform with tunable elasticity.to investigate the impact of elasticity.on antigen-specific T cell activation for in vivo adoptive *** this knowledge,we were able to gain more precise control over in vivo T cell activation and investigate possible mechanisms including the effects of aAPC elasticity.on T cell binding,macrophage uptake,and the protein corona.

关键词： adoptive cell therapy artificial antigen presenting cells particle drug delivery elasticity protein corona poly.ethy.ene gly.ol)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：