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数码先锋 2006年第2期 76-76页

作者： SCEC j.son

在2006年新年的第一天,2005GCCG 终于完满结束。经过激烈的角逐。

关键词：李杰锋 GCCG2005 软件学院广州体育学院车士大资胡仁口强卜人二万

3.0 T MRI影像纹理分析与乳腺癌病人新辅助化疗反应性之间的关系

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国际医学放射学杂志 2020年第2期 231-231页

作者： N.L. Eun D. Kang E.j. son j.S. Park j.H. Youk j.A. Kim 朱羽苑 Department of Radiology Gangnam Severance HospitalYonsei University College of Medicine

既往研究表明,纹理分析在多种肿瘤治疗反应性的诊断、特征描述以及评估中是一种有前景的工具。因此,纹理分析的应用或许有助于早期预测乳腺癌的病理反应。目的

关键词： T MRI 纹理分析乳腺癌病人扩散加权新辅助影像纹理

Endurance Test of Biodiesel Fueled Tractor Engine

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j.urnal of Agricultural Science and Technology(B) 2011年第7期1卷 1025-1031页

作者： Y. j. Kim S. H. Park C. K. Kim D. H. Im Y. j.ng S. S. Kim Department of Agricultural Engineering National Academy of Agricultural Science Rural Development Administration Suwon441- 707 Republic of Korea R＆D Engine Team Daedong Industrial Co. Chang Nyong-Kun Kyungnam 635-806 Republic of Korea

A diesel engine for tractor w.s tested for 250 hours of durability w.th biodiesel fuel of 100%. An engine test cycle w.s designed based on the ISO test code of off-road vehicle. Eight test conditions, combination of three engine speeds and eight engine loads, w.re applied to the engine endurance test, and the engine w.s operated for eight hours in a day. Pow.r output, fuel consumption rate, exhaust gas quality and particulate matter (PM) w.re measured and discussed. For the extensive 250 hours of the tractor diesel engine endurance test no significant changes of pow.r output, fuel consumption rate, exhaust gas quality and PM w.re monitored and authors could not find any difference in the engine patterns of the tw. fuels of BDF100 and light oil. During all the engine endurance test conditions, no abrupt stopping w.s encountered but because of temperature dow. by the cold season the endurance test could not carried out for some periods. PMs w.re collected and the average PM w.s 0.027 g/kw.w.ich w.s far below.than Tier 4 diesel engine PM of 0.3 g/kw.h defined by US EPA PM of the diesel engine class. Overall even 100% biodiesel can be an alternative fuel for light oil for diesel engine operation w.th some considerations for cold season use.

关键词：柴油发动机柴油燃料生物柴油耐久试验拖拉机耐久性试验燃油消耗率可吸入颗粒物

CT碘对比剂的低剂量低流率使用与急性超敏反应的关系：一项观察性研究

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国际医学放射学杂志 2020年第1期 112-112页

作者： H.j.Park j.H.son T.B.Kim M.K.Kang K.Han E.H.Kim 焦晟 Department of Radiology and Research Institute of Radiology University of Ulsan College of MedicineAsan Medical Center

目前对于急性超敏反应与CT碘对比剂使用剂量和注射流率关系的研究较少。目的探讨低剂量及低流率应用CT碘对比剂与急性超敏反应发生率的关系。材料与方法

关键词：注射流率低剂量碘对比剂 CT

Long term follow.up of a family w.th GUCY2D dominant cone dystrophy

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International j.urnal of Ophthalmology(English edition) 2018年第12期11卷 1945-1950页

作者： Georgios Tsokolas Hussein Almuhtaseb Helen Griffiths Fatima Shaw.at Reuben j.Pengelly Sarah Ennis Andrew.Lotery Clinical and Experimental Sciences University of Southampton Eye Unit University Hospital Southampton Human Genetics & Genomic Medicine Faculty of Medicine University of Southampton

AIM: To describe long term follow.up in a family w.th GUCY2D dominant cone dystrophy. METHODS: Optical coherence tomography scans and fundus autofluorescence images w.re obtained. Flash and pattern electroretinograms(ERGs) and occipital pattern reversal visual evoked potentials w.re recorded. RESULTS: Tw. members of the same family(father and son) w.re identified to have the heterozygous R838 C mutation in the GUCY2D gene. The father presented at the age of 45 w.th bilateral bull’s eye maculopathy and temporal disc pallor. Over 13 y of serial follow.up visits, the bull’s eye maculopathy progressed gradually into macular atrophy. Electrophysiological tests w.re significantly degraded suggesting poor macular function. Spectraldomain optical coherence tomography(SD-OCT) scans show.d progressive loss and disruption of the ellipsoid layer at the foveal level. His son presented at the age of 16 w.th bilateral granular retinal pigment epithelial changes in both maculae. Electrophysiological testing w.s initially borderline normal but has gradually deteriorated to show.reduced cone ERGs and macula function. SD-OCT demonstrated gradual macular thinning and atrophy bilaterally. Unlike his father, there w.s no disruption of the ellipsoid ***: Both family members exhibited gradual changes in their fundi, electrophysiological testing and multimodal imaging. Changes w.re milder than those observed in other mutations of the same gene.

关键词： autofluorescence electroretinogram cone dystrophy cone-rod dystrophy GUCY2D spectral-domain optical coherence tomography visual evoked potential

细胞色素P450基因降低动脉粥样硬化小鼠MMP-9表达

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中国分子心脏病学杂志 2010年第6期10卷 344-347页

作者：吴俊陈琛曾和松汪道文湖北武汉华中科技大学同济医学院附属同济医院心血管内科武汉430030

目的研究血管内皮高表达CYP2C8基因能否降低动脉粥样硬化小鼠的MMP-9的表达。方法以20周龄APOEKO+/-CYP2C8Tg+/-和CYP2C8Tg+/-小鼠(n=10/组)为研究对象,相同基因背景和周龄的同窝APOEKO+/-和C57BL/6小鼠设为对照。采用PCR技术鉴定小鼠CY... 详细信息

目的研究血管内皮高表达CYP2C8基因能否降低动脉粥样硬化小鼠的MMP-9的表达。方法以20周龄APOEKO+/-CYP2C8Tg+/-和CYP2C8Tg+/-小鼠(n=10/组)为研究对象,相同基因背景和周龄的同窝APOEKO+/-和C57BL/6小鼠设为对照。采用PCR技术鉴定小鼠CYP2C8+/-基因;油红O染色检测APOEKO+/-CYP2C8Tg+/-、CYP2C8Tg+/-、APOEKO+/-和C57BL/6小鼠主动脉斑块形成面积;用Real-time PCR法检测各组小鼠的主动脉MMP-9基因表达水平,w.stern blot分析各组小鼠的主动脉MMP-9蛋白的表达情况。用ELISA法检测各组小鼠的血浆IL-1β和IL-10。结果 APOEKO+/-CYP2C8Tg+/-和CYP2C8Tg+/-小鼠主动脉斑块形成面积明显减少,Real-time PCR分析显示高表达CYP2C8在主动脉中明显下调MMP-9基因的表达,w.stern blot分析结果显示:高表达CYP2C8在主动脉中明显下调MMP-9蛋白的活性。在血清学上,高表达CYP2C8明显上调IL-10而下调IL-1β。结论高表达CYP2C8基因能够降低小鼠的MMP-9的活性、减低炎性介质水平,通过抗炎和稳定粥样斑块而发挥抗粥样硬化作用。

关键词：细胞色素P450 环氧化二十碳三烯酸动脉粥样硬化 MMP-9

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＂Long Live King Albany!＂： The History of King Lear （1608） and the Revolution in Shakespeare Studies

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History Research 2016年第2期6卷 59-69页

作者： j.hn j. Burke, j.. University of Alabama Tuscaloosa USA

兔胃癌模型淋巴结转移Gadofluorine M与钆喷葡胺增强MRI的表现

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国际医学放射学杂志 2012年第4期 372-372页

作者： j.Y. Lee B. I. Choi K. R. son j. M. Lee S. j. Kim H.S. Park 唐光健 Department of Radiology and Institute of Radiation Medicine Seoul National University College of Medicine Clinical Research Institute Seoul National University Hospital28 Yeongeon - dong Chongno -gu Seoul 110 -744 Republic of Korea

摘要目的对照Gadofluorine M与钆喷葡胺增强MRI诊断兔胃癌模型转移淋巴结。材料与方法研究方案由学院动物保护委员会批准。将VX2癌接种于20只兔的胃壁。接种后4～6周行钆喷葡胺增强MRI检查,而Gadofluorine M增强MRI扫描于接种后约24h进... 详细信息

摘要目的对照Gadofluorine M与钆喷葡胺增强MRI诊断兔胃癌模型转移淋巴结。材料与方法研究方案由学院动物保护委员会批准。将VX2癌接种于20只兔的胃壁。接种后4～6周行钆喷葡胺增强MRI检查,而Gadofluorine M增强MRI扫描于接种后约24h进行。由4名放射医生分别独立分析MR影像

关键词：淋巴结淋巴组织胃癌模型 Gadofluorine M MRI

基于B超、血管超声与RNA测序的乳腺癌影像基因组学分析

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国际医学放射学杂志 2020年第3期 362-362页

作者： A.Y.Park M.Han K.H.Park j.S.Kim G.S.son H.Y.Lee 马跃 Department of Radiology Korea University Ansan Hospital Korea University College of Medicine

摘要乳腺癌的影像基因组学研究提供了对肿瘤异质性的理解,并探索了遗传变异的影像表型。但关于乳腺癌超声特征与全转录组分析的相关性研究较少。目的通过比较肿

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肝脏脂肪浸润:应用临床MR系统的双相T1梯度回波进行检测和分级

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世界核心医学期刊文摘（胃肠病学分册） 2006年第6期2卷 23-24页

作者： Pilleul F. Chave G. Dumortier j. 成虹(译) 郑世成(校) Service de Radiologie Digestive Hopital Edouard Herriot Place d'Arsonval 69003 Lyon 不详

Aim-To evaluate the relationship betw.en histopathology results and magnetic resonance imaging (MRI) on in-and opposed-phase sequences grading of fat deposition w.thin human liver. Materials and methods-In-and opposed-phase T1-w.ighted gradient-echo sequences (double echo time 2.3 ms and 4.6ms)w.re performed in 25 patients,using a 1.5-T clinical MR imaging system. Fat/w.ter ratio on in-and opposed-phase images of the liver w.s compared w.th pathologically defined degree or steatosis. The signal intensity in the images w.s acquired w.th operator-defined regions of interest at the same location in both fat and w.ter images and the ratio w.s calculated by dividing signal intensity of liver in opposed phased sequence on signal intensity of liver in phased sequence. Fat/w.ter ratio and the degree of steatosis w.re compared using linear regression. The sensitivity and specificity of opposed-phase for diagnosing steatosis w.re defined by ROC analysis. Furthermore, a correlation betw.en visual signal intensity variation (SIV)and the degree of steatosis w.s assessed using Pearson correlation coefficient. Results-Histology demonstrated fatty liver infiltrations in 81 %of specimens. The percentage of fatty hepatocytes w.s 28 +/-30 %. Fat/w.ter ratio w.s significantly correlated w.th the pathologic grading of steatosis (r = 0.816, P w.re respectively 80%and 71%. w. obtained a statistically significant correlation betw.en visual SIV and fatty liver grading (P = 0.017). Conclusion-w. demonstrated a significant correlation betw.en fat/w.ter ratio and histological findings for the detection and grading of fatty liver.

关键词：肝脏脂肪浸润梯度回波序列 MR系统应用临床双相检测肝脏脂肪变性组织病理学成像系统

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