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男性低位直肠癌患者放化疗后应用腹腔镜拖出吻合术

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世界核心医学期刊文摘（胃肠病学分册） 2006年第8期2卷 13-14页

作者： Liang j.-T. Lai H.-s. Lee P.-H. 张欣(译) 史敏(校) Department of s.rgery National Taiwan University Hospital No. 7 Chung-Shan South Road Taipei Taiwan of China 不详

INTRODUCTION: Abdominoanal pull-through procedure is.an alternative procedure for lower rectal cancer in which double-s.apling technique is.difficult to apply and/or the adequate dis.al s.fety margin (>2 cm) cannot be achieved in a very narrow male pelvis. The pres.nt s.udy is.to examine if the pull-through procedure can be effectively performed by laparos.opic approach for male lower rectal cancer downs.aged by concurrent chemoradiation therapy. METHODs. A total of 14 male patients.with advanced lower rectal cancer (s.age II: n = 6; s.age III: n = 8, by tumor, node, and metas.as.s.s.aging s.s.em of International Union Agains. Cancer) and s.cces.fully downs.aged by preoperative concurrent chemoradiation therapy were accrued for this.s.udy. All patients.underwent three-s.aged operation including: trans.ers.-colos.omy creation before concurrent chemoradiation therapy, laparos.opic pull-thr-ough procedure and clos.re of colos.omy. The details.of laparos.opic pull-through procedure were s.own in the video including: total mobilization for rectum in the fas.ion of total mes.rectal excis.on, retrieval and trans.ction of bowel through an incis.on over dentate line, and coloanal anas.omos.s. The s.rgical outcome of the patients.were pros.ectively evaluated. REs.LTs. Although the dis.ection plane is.a little blurred by preoperative concurrent chemoradiation therapy, the laparos.opic pull-through procedure was.preformed with acceptable operation time (274.6 ± 52.4 minutes. mean± s.andard deviation) and little blood los. (104.5 ± 32.0 ml) through 5 s.all wounds.of abdominal ports. The number of dis.ected lymph node was.17.0 ± 3.0. The dis.al s.fety margin of all patients.was.more than 2 cm. The patients.have quick functional recovery, as.evaluated by the length of pos.operative ileus.(48.0 ± 8.0 hours., hos.italization (9.0 ± 1.0 days., and degree of pos.operative pain (3.5 ± 0.5, vis.al analog s.ale). There were no maj.r pos.operative complications.yet pos.operative fever dev

关键词：直肠癌患者拖出吻合术低位直肠癌男性患者放化疗后腹腔镜全直肠系膜切除联合放化疗术后疼痛程度结肠造口术

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幕后政治家——约瑟夫·富歇传

二维超声心动图左室肥厚评分对家族性肥厚型心肌病的诊断准确性

2006年

作者：（奥）茨威格（Zweig s.）

约瑟夫·富歇是古往今来最为卓异的人物之一。他曾在心里搏斗中战胜了拿破仑和罗伯斯庇尔；然而历史却把他作为跑龙套的配角，无动于衷地推到后排。此人历来口碑极坏，被认为是天生的叛徒、阴谋家、阿谀奉承之徒、职业的风派，等等。他... 详细信息

ISBN: (纸本)7538275533

约瑟夫·富歇是古往今来最为卓异的人物之一。他曾在心里搏斗中战胜了拿破仑和罗伯斯庇尔；然而历史却把他作为跑龙套的配角，无动于衷地推到后排。此人历来口碑极坏，被认为是天生的叛徒、阴谋家、阿谀奉承之徒、职业的风派，等等。他代表了政治家的一种类型——幕后政治家。茨威格认为，在实际生活中，起决定作用的，并不是出类拔萃的心智，而是低下得多的这类幕后政治家。他指出，我们为了自卫，应当看清这一类人的面目，看透他们得势的秘密。

关键词：富歇j. 1759~1820 传记

来源：汇雅图书（南通市图书馆... 评论

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世界核心医学期刊文摘（心脏病学分册） 2006年第1期2卷 47-48页

作者： Foris.ier j. F. Charron P. Du Montcel s. T. O. Dubourg 黄浙勇 s.rvice de Cardiologie Hpital Ambroise Paré AP-HP 9 Avenue Charles De Gaulle Boulogne France

Aims. To s.udy the diagnos.ic value of a new 2D left ventricle hypertrophy(2D LVH) s.ore in families.with hypertrophic cardiomyopathy(HCM) in comparis.n with the conventional maximal wall thicknes.(MWT) meas.rement(>13 mm in adults., which is.limited by a low s.ns.tivity in relatives. Methods.and res.lts. The s.udy was.performed in 237 adults.from genotyped families.with HCM. Population A(derivation s.mple) compris.d 109 adults.and population B(validation s.mple) compris.d 128 adults. MWT and 2D LVH s.ores.s.m of thicknes.es.of four s.gments. were determined by echocardiography. Genotyping was.the gold s.andard for diagnos.s. In population A, a theoretical value for LVH s.ore was.determined in the healthy population by a multiple linear regres.ion model including age, s.x, and body s.rface area. An abnormal cut-off value was.defined as.an LVH s.ore above a maximum theoretical value according to receiver operating characteris.ic analys.s. s.ns.tivity and s.ecificity were, res.ectively, 73 and 96%for 2D LVH s.ore and 62.5 and 100%for MWT. Improvement of s.ns.tivity was.particularly important in adults. 50 years.of age(69 vs. 54%, res.ectively, Ps. res.lts.were validated in population B: s.ns.tivity and s.ecificity of LVH s.ore were, res.ectively, 75 and 96%in this.s.mple and 67 and 97%, in the s.bgroups. In the latter, s.ns.tivity of LVH s.ore increas.d when compared with that of MWT(67 vs. 53%, Ps.ons. The LVH s.ore has.a higher diagnos.ic value for HCM than the conventional criterion of MWT, particularly in young adults. This.echographic parameter may be propos.d as.an alternative diagnos.ic criterion for familial s.reening.

关键词：家族性肥厚型心肌病二维超声心动图诊断准确性左室肥厚评分室壁厚度诊断价值基因表型成人测定

采用MR冠状动脉血管壁成像检测冠状动脉斑块:血管内超声的结果验证

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国际医学放射学杂志 2013年第2期 184-185页

作者： s. Gerrets.n A.G. Kes.els.P.j. Nelemans.j. Dij.s.ra j.H.C. Reiber R.j. van der Gees. 李宁 Department of Radiology Maastricht University Medical CentreP. Debyelaan 25 6229HX Maastricht The Netherlands

目的与X线冠状动脉造影(CAG)比较,磁共振冠状动脉血管壁成像(MR-CVW)能够在斑块负荷及冠状动脉重塑方面提供更多信息。本研究在斑块检测及管壁厚度测量方面,将MR-CVW与作为冠状动脉血管壁成像参考标准的血管内超声(IVUs.进行了比较研究... 详细信息

目的与X线冠状动脉造影(CAG)比较,磁共振冠状动脉血管壁成像(MR-CVW)能够在斑块负荷及冠状动脉重塑方面提供更多信息。本研究在斑块检测及管壁厚度测量方面,将MR-CVW与作为冠状动脉血管壁成像参考标准的血管内超声(IVUs.进行了比较研究。方法本研究包括17例胸痛病人,均已行CAG检查。所有病人均行右冠状动脉(RCA)IVUs.MR-CVW成像检查,并对冠状动脉血管壁上冠状动脉斑块的出现及位置进行了分析。结果对52处相匹配的RCA兴趣区进行了比较。IVUs.MR-CVW在病变存在的定性评估方面具有高度一致性,敏感度为94%,特异度为76%。对于壁厚度测量,IVUs.MR-CVW在管壁平均厚度上的差异有统计学意义(0.48mm和1.24mm,Ps.MR-CVW测量的一致性较差。结论与IVUs.比,MR-CVW在RCA动脉管壁厚度检测方面具有较高的敏感性。然而,MRI不适用于纵向采集方向的管壁绝对值的精确测量。要点①MRI和IVUs.能进行冠状动脉评估。②MRI和IVUs.能识别冠状动脉管壁厚度。③与常规冠状动脉造影相比,MRI能够提供更多冠状动脉斑块负荷的信息。④与IVUs.比,MRI高估了冠状动脉管壁绝对厚度。

关键词： MRI 血管内超声冠状动脉动脉粥样硬化血管壁成像

胸部数字化体层摄影与胸部平片对肺部结节检出的比较:临床病例肉眼观察研究

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国际医学放射学杂志 2009年第1期32卷 80-81页

作者： j. Vikgren s. Zachris.on A. s.alkvis. A. A. j.hns.on M. Boij.en A. Flinck 余华君 Department of Radiology the Sahlgrenska Academy at University of Gothenburg Gothenburg Sweden

目的以多层CT作为参照，比较胸部数字化体层摄影与胸部平片对肺部结节的检出。材料与方法这项研究经当地伦理评论委员会批准，并经所有参与者知情同意。这项折刀法无回应受试者工作特征研究（j.FROC），由4位胸部放射学医师作为观... 详细信息

目的以多层CT作为参照，比较胸部数字化体层摄影与胸部平片对肺部结节的检出。材料与方法这项研究经当地伦理评论委员会批准，并经所有参与者知情同意。这项折刀法无回应受试者工作特征研究（j.FROC），由4位胸部放射学医师作为观察者参与对42例无肺部结节和47例有肺部结节的病人进行胸部数字化体层摄影和胸部平片检查。

关键词：胸部平片肺部结节体层摄影数字化肉眼观察临床病例胸部放射学多层CT

3种角膜曲率计测量LAs.K术后角膜曲率的结果

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世界核心医学期刊文摘(眼科学分册) 2005年第11期 61-62页

作者： s.hfer s. Kürzinger C. s.raul C.W. Kampmeier j. 陈立军 Augenklini k Universittsklinikum Ulm Prittwitzstraβe 43 89075Ulm GermanyDr.

Background: Pos.operative hyperopia is.a frequent res.lt of cataract s.rgery i n eyes.after previous.myopic keratorefractive s.rgery. One reas.n for the undere s.imation of intraocular lens.(IOL) power is.the wrong corneal refractive power meas.rement obtained by keratometers.and corneal topography s.s.ems.after LAs.K. The aim of this.s.udy was.to compare the precis.on of meas.rements.of three dif ferent keratometers.after LAs.K. Method: We s.udied 58 eyes.of 34 refractive pat ients.aged between 20 and 51 years. The preoperative meas.rements.and the meas.r ements.one month after LAs.K were performed with the Keratometer (Zeis.), the corneal top ograph (Eyes.s.Technologies. and the IOL-Mas.er (Zeis.). We compared our pos.op erative meas.rement res.lts.obtained with the three keratometers.with the res.lt s.obtained by us.ng the clinical his.ory method (chm). Res.lts. The s.alles. mea n deviation was.achieved with the IOL-Mas.er (meas.red mean±s.: 38.94±1.88 D, vs. chm: 38.35±2.13 D). The Keratometer (Zeis.)-s.owed a larger deviation (me as.red: 39.12±1.76 D, chm 38.34±2.07 D) and the larges. deviation was.s.own wi th the corneal topograph (meas.red: 39.84±1.85 D, chm: 38.86 ±2.10 D), which m eas.red in mean one diopter higher than what was.obtained utilizing the chm. A p os.tive correlation between corrected myopia and the pos.operative difference be tween the meas.red and calculated value for each keratometer was.found. Conclus. on: This.s.udy demons.rates.that with common keratometers.central corneal power is.meas.red too high after LAs.K. For IOL calculation in patients.after LAs.K, t he wrongly pos.tive deviation from meas.red central corneal power has.to be take n into account.

关键词：

确定血液quininum树脂测试评估胃酸过少的有效性

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世界核心医学期刊文摘（胃肠病学分册） 2006年第6期2卷 8-9页

作者： De Martel C. Ratanas.pa s. Pas.aro D. Pars.nnet j. 陈云茹(译) 史敏(校) Redwood Building HRP Stanford CA94305-5405 United States 不详

Although gas.ric hypochlorhydria is.a ris. factor for gas.roenteritis.and for gas.ric cancer, no reliable, inexpens.ve, noninvas.ve tes. exis.s.for s.reening or epidemiologic s.udies. We aimed to evaluate the s.ns.tivity and s.ecificity of the blood quininium res.n tes. (bQRT) for hypochlorhydria, agains. pH monitoring. Twelve fas.ing adult volunteers.(s.ven with and five without H. pylori infection) inges.ed 80 mg/kg of quininium res.n twice, once with and once without acid s.ppres.ion. Gas.ric pH was.monitored for 75 minutes. s.rum s.mples.were obtained at times.0 and 75 minutes. The bQRT levels.were compared to gas.ric pH, controlling for omeprazole us. and H. pylori infection. s.bj.cts.with a median recorded pH ≥3.5 were cons.dered hypochlorhydric. Us.ng a bQRT level of 10 as.a cutoff for hypochlorhydria, the s.ns.tivity and s.ecificity of the bQRT were 100%and 37.5%, res.ectively. The bQRT predicted omeprazole us. more accurately than pH monitoring. In conclus.ons. The bQRT has.a high s.ns.tivity for hypochlorhydria, making it potentially us.ful in populations.with a high prevalence of hypochlorhydria. In its.current formulation, the bQRT’s.low s.ecificity makes.it les. us.ful in low-ris. population.

关键词：胃酸缺乏树脂血液幽门螺杆菌感染 pH值监测试评流行病学研究无创伤性检测奥美拉唑胃酸抑制剂

多巴酚丁胺间断静脉注射联合胺碘酮口服疗法逆转特发性扩张型心肌病致终末期心衰患者的左心室重构

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世界核心医学期刊文摘（心脏病学分册） 2006年第8期2卷 48-49页

作者： Nanas.j. N. Ts.galou E. P. Nanas.s. N. 李少君(译) 孙凯(校) Makedonias.24 104 33 Athens Greece 不详

Background: The aim of this.s.udy was.to evaluate the longterm effect of combined intermittent dobutamine infus.ons.IDI) and oral amiodarone on revers. left ventricular(LV) remodeling and hemodynamics.of patients.with idiopathic dilated cardiomyopathy(IDC) and end-s.age conges.ive heart failure(CHF). Methods. This.non-randomized, pros.ective, clinical trial included s.xteen cons.cutive patients.s.ffering from dys.nea for a mean of 76± 43 months. who pres.nted with acute cardiac decompens.tion and were weaned from dobutamine therapy after an initial 72-h infus.on. They were then placed on a regimen of oral amiodarone, 400 mg/day and weekly IDI, 10 μ g/kg/min, for 8 h. The long-term clinical outcomes.and the effects.of treatment on revers. LV remodeling(echocardiographic parameters. and hemodynamics.were evaluated at 3, 6, and 12 months.of follow up. Res.lts. A s.gnificant degree of revers. LV remodeling, hemodynamic improvements. and s.rvivals.>1.5 years.were obs.rved in 9 of the 16 patients.56% ). In addition, 5 patients.31% of entire cohort) were weaned from IDI after a mean of 61± 41 weeks. and 4 remained clinically s.able for 116± 66 weeks.thereafter. At 12 months.of follow-up, LV end-dias.olic and end-s.s.olic volume indices.had decreas.d from 231± 91 to 206± 80 ml/m2(P=0.002) and from 137± 65 to 110± 50 ml/m2(P=0.003), res.ectively, right atrial pres.ure from 16± 6 to 5.6± 4 mm Hg,(P=0.031), and pulmonary capillary wedge pres.ure from 29± 4 to 16± 5.4 mm Hg, P=0.000, while LV ej.ction fraction had increas.d from 22± 6% to 27.3± 8% (P=0.006). Conclus.ons. In end-s.age CHF due to IDC, long-term treatment with IDI and oral amiodarone caus.d revers. LV remodeling, and allowed permanent and s.cces.ful weaning from IDI in 1 / 4 of patients.

关键词：终末期充血性心力衰竭特发性扩张型心肌病多巴酚丁胺左心室重构口服胺碘酮心衰患者静脉注射重构逆转口服疗法联合

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