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Effects of Sheared Flow on Microinstabilities and Transport in Plasmas

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Plasma Science and Technology 2005年第1期7卷 2610-2614页

作者： H.Sanuki K.Itoh A.Fujisawa j.q.dong National Institute for Fusion Science Toki Gifu 509-5292 JapanNational Institute for Fusion Science Toki Gifu 509-5292 JapanNational Institute for Fusion Science Toki Gifu 509-5292 JapanSouthwestern Institute of Physics Chengdu 610041 China

Theoretical and experimental studies associated with electric field effectson the stability and transport are briefly surveyed. The effects of radial electric field on thesuppression and/or enhancement of various microinstabilities such as drift waves, flute mode andtemperature gradient modes are discussed. The suppression of flow shear on the electron temperaturegradient mode in plasmas with slightly hollow density profiles is investigated by solving thegyrokinetic integral eigenvalue equation. Comparison between theoretical predictions andexperimental observations based on the HIBP measurements with high temporal and spatial resolutionsis made in bumpy tori and heliotron (CHS) devices.

关键词： sheared flow microinstabilities transport bumpy tori heliotron

Simultaneous high-resolution x-ray backlighting and self-emission imaging for laser-produced plasma diagnostics using a two-energy multilayer Kirkpatrick–Baez microscope

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Matter and Radiation at Extremes 2022年第1期7卷 47-52页

作者： S.Z.Yi j.q.dong L.jiang q.S.Huang E.F.Guo Wang Z.S. MOE Key Laboratory of Advanced Micro-Structured Materials No.1239 Siping RoadShanghai 200092China School of Physics Science and Engineering Tongji UniversityShanghai 200092China Shanghai Institute of Laser Plasma CAEPP.O.Box 919-988Shanghai 201800China

A simultaneous high-resolution x-ray backlighting and self-emission imaging method for laser-produced plasma diagnostics is developed in which two Kirkpatrick–Baez imaging channels for high-energy and low-energy diagnostics are constructed using a combination of multilayer mirrors in near-coaxial *** using a streak or framing camera placed on the image plane,both backlit and self-emission images of a laserproduced plasma with high spatial and temporal resolution can be obtained simultaneously in a single *** paper describes the details of the method with regard to its optical and multilayer design,assembly,and alignment *** addition,x-ray imaging results with a spatial resolution better than 5μm in the laboratory and experimental results with imploding capsules in the SG-III prototype laser facility are presented.

关键词： method. multilayer resolution

Simulation of Fusion Plasmas:Current Status and Future Direction

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Plasma Science and Technology 2007年第3期9卷 312-387页

作者： D.A.Batchelor M.Beck A.Becoulet R.V.Budny C.S.Chang P.H.Diamond j.q.dong G.Y.FU A.Fukuyama T.S.Hahm D.E.Keyes Y.Kishimoto S.Klasky L.L.Lao K.Li Z.Lin B.Ludaescher j.Manickam N.Nakajima T.Ozeki N.Podhorszki W.M.Tang M.A.Vouk R.E.Waltz S.j.Wang H.R.Wilson X.q.Xu M.Yagi F.Zonca Oak Ridge National Laboratory Oak RidgeTN 37831USA 1122 Volunteer Blvd Suite 203KnoxvilleTN 37996-3450USA AssociationEURATOM-CEA sur la Fusio n Contr■lée CEA Cadarache13108 Saint Paul lez Durance CedexFrance Princeton Plasma Physics Laboratory Princeton UniversityPrincetonNJ 08543USA Courant Institute of Mathematical Sciences New York University251 Mercer StreetNew YorkNY 10012USA University of California at San Diego Dept.of Physics and Center for Astrophysics and Space SciencesLa JollaCA 92093USA Southwestern Institute of Physics Chengdu 610041China Department of Nuclear Engineering Kyoto UniversityKyoto 606-8501Japan Columbia University Department of Applied Physics and Applied MathematicsMC 4701New YorkNY 10027USA Department of Fundamental Energy Science Graduate School of Energy ScienceKyoto UniversityGokashoUjiKyoto 611-0011Japan General Atomics P.O.Box 85608San DiegoCA 92186USA Department of Computer Science Princeton University PrincetonNJ 08544USA Department of Physics and Astronomy University of CaliforniaIrvineCA 92697USA Department of Computer Science University of California DavisCA95616USA National Institute for Fusion Science TokiGifu 509-5292Japan japan Atomic Energy Agency Naka Fusion Research EstablishmentNaka-machiIbaraki-kenJapan Department of Computer Science North Carolina State UniversityRaleighNC 27695USA Department of Physics Fudan University200433 ShanghaiChina Department of Physics University of YorkHeslingtonYork YO10 5DD UK Lawrence Livermore National Laboratory LivermoreCA 94550USA Research Institute for Applied Mechanics Kyushu UniversityKasuga 816-8580Japan Associazione Euratom-ENEA sulla fusione CR FrascatiCasella Postale 65-00044FrascatiItaly

I. Introduction (Z. Lin, G. Y. Fu, j. q. dong) II. Role of theory and simulation in fusion sciences 1. The Impact of theory and simulation on tokomak experiments (H. R. Wilson, T.S. Hahm and F. Zonca) 2. Tokomak Transport Physics for the Era of ITER: Issues for Simulations (P.H. Diamond and T.S. Hahm) III. Status of fusion simulation and modeling 1. Nonlinear Governing Equations for Plasma Simulations (T. S. Hahm) 2. Equilibrium and stability (L.L. Lao, j. Manickam) 3. Transport modeling (R.E. Waltz) 4. Nonlinear MHD (G.Y. Fu) 5. Turbulence (Z. Lin and R.E. Waltz) 6. RF heating and current drive (D.A. Batchelor) 7. Edge physics Simulations (X.q. Xu and C.S. Chang) 8. Energetic particle physics (F. Zonca, G.Y. Fu and S.j. Wang) 9. Time-dependent Integrated Modeling (R.V. Budny) 10. Validation and verification (j. Manickam) IV. Major initiatives on fusion simulation 1. US Scientific Discovery through Advanced Computing (SciDAC) Program & Fusion Energy Science (W. Tang) 2. EU Integrated Tokamak Modelling (ITM) Task Force (A. Becoulet) 3. Fusion Simulations Activities in japan (A. Fukuyama, N. Nakajima, Y. Kishimoto, T. Ozeki, and M. Yagi) V. Cross-disciplinary research in fusion simulation 1. Applied mathematics: Models, Discretizations, and Solvers (D.E. Keyes) 2. Computational Science (K. Li) 3. Scientific Data and Workflow Management (S. Klasky, M. Beck, B. Ludaescher, N. Podhorszki, M.A. Vouk) 4. Collaborative tools (j. Manickam)

关键词： mode ITER

The Research on Expression of Platelet Activation Markers and CD62P in Patients with Acute Cerebral Ischemic Stroke and Influence of Using of Anti-Platelet Drugs

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The Research on Expression of Platelet Activation Markers an...

Selection against abdominal fat percentage may increase intramuscular fat content in broilers

第4届国际脑血管病高峰论坛

作者： S Xu,L Wang,j qiao,q dong,L Zhou Department of Neurology,Huashan Hospital affliated to Fudan University,Shanghai 200040,China

Objective:To study the influence of different anti-platelet drugs(aspirin and ADP antagonists) on the expressions of platelet activation markers in patients with acute cerebral ischemic stroke and provide reliable theoretical references for the prevention and therapy of acute cerebral ***:Flow cytometry was used to examine CD62P,the platelet activation markers in patients with

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Selection against abdominal fat percentage may increase intr...

Strain Growth in Containment Vessels

第七届中国畜牧科技论坛

作者： L.Leng H.Zhang j.q.dong Z.P.Wang X.Y.Zhang S.Z.Wang Z.P.Cao Y.M.Li H.Li Key Laboratory of Chicken Genetics and Breeding Ministry of Agriculture

Excessive abdominal fat content(AFC) has negative impacts on feed efficiency and carcass *** AFC,intramuscular fat content(IMFC) could be a favorable trait,which has a positive impact on meat *** meet consumers’ needs,a long-term goal of broiler breeders is to decrease AFC and improve the IMFC *** current study was designed to investigate the relationship between AFC and IMFC and to compare IMFC,including the pectoral major muscle fat content(PIMFC) and intramuscular fat content of leg muscle(LIMFC),between two broiler lines divergently selected for abdominal fat percentage over 17 *** results showed that there was a significant difference in PIMFC and LIMFC between the two lines in all five generation populations *** birds in the lean line had significantly lower AFC but higher PIMFC and LIMFC than the birds in the fat *** also detected differences in the liver fat content(LFC) between the two lines and the results showed that birds in the fat line had significant higher LFC than birds in the lean *** results indicated that a desirable broiler line with higher IMFC but lower AFC could be obtained by genetic selection.

关键词： abdominal fat content intramuscular fat content liver fat content chicken

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Transactions of Tianjin University 2006年第B09期12卷 193-198页

作者： dong q LI q M ZHENG j Y School of Mechanical Aerospace and Civil Engineering The University of Manchester PO Box 88 Manchester M60 1QD UK Institute of Chemical Machinery Zhejiang University Hangzhou 310027 China

Strain growth is a phenomenon observed in containment vessels subjected to internal blast loading. The elastic response of the vessel may become larger in a later stage compared to its response during the initial stage. The dynamic responses of infinitely long cylindrical containment vessels subjected to uniformly-distributed internal blast loading are studied using LS-DYNA. The development of bending modes and the interaction between the breathing mode and bending modes are observed. The methodology developed for dynamic elastic buckling analysis is employed to study the strain growth phenomenon in explosion containment vessels. It is shown that the dynamic instable vibration of a containment vessel is the basic mechanism of strain growth.

关键词： strain growth containment vessel dynamic response impulsive loading

Macroscopic and microscopic mechanical behaviors of climbing tendrils

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Acta Mechanica Sinica 2019年第3期35卷 702-710页

作者： q.Guo j.j.dong Y.Liu X.H.Xu q.H.qin j.S.Wang Tianjin Key Laboratory of Modern Engineering Mechanics Department of MechanicsTianjin UniversityTianjin 300054China State Key Laboratory of Nonlinear Mechanics (LNM) Institute of MechanicsChinese Academy of ScienceBeijing 100080China Research School of Engineering Australian National UniversityCanberraACT 2601Australia

Tendril-bearing climbing plants must recur to the tendril helices with chiral perversion or dual chirality for climbing and to obtain sun exposure. Despite researchers' prolonged fascination with climbing tendrils since Darwin's time and even earlier, why the soft and slender tendrils can bear heavy loads such as the self-weight of a plant or additional load caused by rain remains elusive. In this paper, we take towel gourd tendrils as an example and investigate the macroscopic and microscopic mechanical behaviors of tendrils through experiments and simulations. Our study indicates that the tendril filament exhibits rubber-like hyperelastic behaviors and can particularly endure large elongation, which is mainly attributed to the superelasticity of the cellulose fibril helix contained in the cell wall. Combination of the tendril helical structure with dual chirality or chiral perversion at a macroscale and a cellulose filament helix at a subcellular level creates superior elasticity for biological species relying on support and climbing. This study provides deep insight into the structure-property relationship of climbing tendrils, and the relationship is useful for the bioinspired design of composite systems with superior elasticity.

关键词： Climbing tendril Mechanical behaviors Structure-property relationship Large elongation

Adiponectin signaling and function in insulin target tissues

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journal of Molecular Cell Biology 2016年第2期8卷 101-109页

作者： Hong Ruan Lily q.dong Department of Pharmacology University of Texas Health Science Center at San Antonio7703 Floyd Curl DriveSan AntonioTX 78229USA Department of Cell and Structural Biology University of Texas Health Science Center at San Antonio7703 Floyd Curl DriveSan AntonioTX 78229USA

Obesity-linked type 2 diabetes is one of the paramount causes of morbidity and mortality worldwide,posing a major threat on human health,productivity,and quality of *** great progressmadetowards a better understanding of the molecular basis of diabetes,the available clinical counter-measures against insulin resistance,a defect that is central to obesity-linked type 2 diabetes,remain ***,an abundant adipocyte-secreted factor with a wide-range of biological activities,improves insulin sensitivity in major insulin target tissues,modulates inflammatory responses,and plays a crucial role in the regulation of energy ***,adiponectin as a promising therapeutic approach has not been thoroughly explored in the context of pharmacological intervention,and extensive efforts are being devoted to gain mechanistic understanding of adiponectin signaling and its regulation,and reveal therapeutic ***,we discuss tissue-and cell-specific functions of adiponectin,with an emphasis on the regulation of adiponectin signaling pathways,and the potential crosstalk between the adiponectin and other signaling pathways involved in metabolic *** better just why and how adiponectin and its downstream effector molecules work will be essential,together with empirical trials,to guide us to therapies that target the root cause(s)of type 2 diabetes and insulin resistance.

关键词： adiponectin insulin resistance cell signaling APPL1 APPL2 adiponectin receptor

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway

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Neural Regeneration Research 2025年第11期20卷 3245-3258页

作者： jiayi Wang Mengke Zhao dong Fu Meina Wang Chao Han Zhongyue Lv Liang Wang jing Liu Stem Cell Clinical Research Center The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning ProvinceChina Dalian Innovation Institute of Stem Cell and Precision Medicine DalianLiaoning ProvinceChina Institute(College)of Integrative Medicine Dalian Medical UniversityDalianLiaoning ProvinceChina

Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem cell therapy and advancing the frontiers of stem cell-derived *** lays a foundation for the development of potentially potent new treatment modalities for ischemic ***,the precise mechanisms underlying the efficacy and safety of human neural stem cell-derived extracellular vesicles remain unclear,presenting challenges for clinical *** promote the translation of therapy based on human neural stem cell-derived extracellular vesicles from the bench to the bedside,we conducted a comprehensive preclinical study to evaluate the efficacy and safety of human neural stem cell-derived extracellular vesicles in the treatment of ischemic *** found that administration of human neural stem cell-derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal *** human neural stem cell-derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase,mammalian target of rapamycin,and protein kinase B,and these effects were reversed by treatment with a phosphoinositide 3-kinase *** findings suggest that human neural stem cell-derived extracellular vesicles play a neuroprotective role in ischemic stroke through activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling ***,we showed that human neural stem cell-derived extracellular vesicles have a good in vivo safety ***,human neural stem cell-derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.

关键词： behavior exosome extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)