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journal of Agricultural Science and Technology(B) 2019年第5期9卷 356-364页

作者： Raísa Turcato de Oliveira Andréia Santos Cezário Wallacy Barbacena Rosa dos Santos jéferson corrêa ribeiro Tiago Neves Pereira Valente Hellen Cardoso de Oliveira Departament of Animal Science Instituto Federal Goiano(IFGoiano)Campus Morrinhos75650-000Goiás StateBrasil Department of Animal Science Instituto Federal Goiano(IFGoiano)Campus Posse73900-000Goiás StateBrasil

The objective of this study was to evaluate the effects of the addition of souari nut peel on the fermentative characteristics and chemical composition of the Mombasa grass silage.A completely randomized design with five levels of addition(0%,5%,10%,15%and 20%in natural matter basis)of souari nut peel with three replicates was applied in the *** silos were opened at 55 d after starting the ensiling *** data were analyzed by means of linear/quadratic regression analysis,according to the best fit of the data and the probability values to 5%,using the Statistical Analysis System(SAS,2002).There were a linear decreasing effect on the neutral detergent fiber(NDF),ash and increasing values for the effluent in the *** effect was observed for crude protein(CP),lignin and *** the other factors dry matter(DM),acid detergent fiber(ADF)and gases there was no influence on the addition of souari nut *** 15%addition level of souari nut peel increased CP content,decreased NDF and pH,which was recommended to improve the fermentation profile of Mombasa grass silage.

关键词： Additive effluent production fermentation quality

Contribution of mechanical forces to structural synaptic plasticity:insights from 3D cellular motility mechanisms

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Neural Regeneration Research 2025年第7期20卷 1995-1996页

作者： Rita O.Teodoro Mafalda ribeiro Ramos Lara Carvalho iNOVA4Health NOVA Medical School|Faculdade de Ciências MédicasNMS|FCMUniversidade Nova de LisboaLisboaPortugal

Cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no ***-intrinsic properties such as membrane lipid composition,abundance of mechanosensors,and cytoskeletal dynamics make cells more or less likely to sense these *** and extrinsic cues are integrated by cells and this combined information determines the rate and dynamics of membrane protrusion growth or retraction(Yamada and Sixt,2019).Cell protrusions are extensions of the plasma membrane that play crucial roles in diverse contexts such as cell migration and neuronal synapse *** the nervous system,neurons are highly dynamic cells that can change the size and number of their pre-and postsynaptic elements(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called *** plasticity is a hallmark of the nervous system and is present throughout our lives,being required for functions like memory formation or the learning of new motor skills(Minegishi et al.,2023;Pillai and Franze,2024).

关键词： plasticity structural mechanisms

Current role of extracorporeal membrane oxygenation for the management of trauma patients:Indications and results

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World journal of Critical Care Medicine 2025年第1期14卷 42-48页

作者： Mohammed Abdulrahman Maryam Makki Malak Bentaleb Dana Khamis Altamimi Marcelo AF ribeiro junior Department of Surgery College of Medicine and Health SciencesKhalifa UniversityAbu Dhabi 11001United Arab Emirates Department of Surgery Division of TraumaCritical Care and Acute Care SurgerySheikh Shakhbout Medical CityAbu Dhabi 11001United Arab Emirates Department of Surgery Sheikh Shakhbout Medical CityAbu Dhabi 91888ADUnited Arab Emirates Department of Surgery R Adams Cowley Shock Trauma CenterUniversity of MarylandBaltimoreMD 21201United States

Extracorporeal membrane oxygenation(ECMO)has emerged as a vital circulatory life support measure for patients with critical cardiac or pulmonary conditions unresponsive to conventional *** allows blood to be extracted from a patient and introduced to a machine that oxygenates blood and removes carbon *** blood is then reintroduced into the patient’s circulatory *** process makes ECMO essential for treating various medical conditions,both as a standalone therapy and as adjuvant ***-venous(VV)ECMO primarily supports respiratory function and indicates respiratory ***,veno-arterial(VA)ECMO provides hemodynamic and respiratory support and is suitable for cardiac-related *** study reviews recent literature to elucidate the evolving role of ECMO in trauma care,considering its procedural intricacies,indications,contraindications,and associated ***,the use of ECMO in trauma patients,particularly for acute respiratory distress syndrome and cardiogenic shock,has demonstrated promising outcomes despite challenges such as anticoagulation management and complications such as acute kidney injury,bleeding,thrombosis,and *** studies have shown that VV ECMO was associated with significantly higher survival rates than conventional mechanical ventilation,whereas other studies have reported that VA ECMO was associated with lower survival rates than VV *** plays a critical role in managing trauma patients,particularly those with acute respiratory *** research is necessary to explore the full potential of ECMO in trauma *** should have a clear understanding of the indications and contraindications for the use of ECMO to maximize its benefits in treating trauma patients.

关键词： Extracorporeal membrane oxygenation treatments Multiple trauma Respiratory distress syndrome Cardiogenic shock Contraindications Anticoagulants

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

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MECA认知架构的更新（英文）

宁波大学学报(理工版) 2025年第02期 29-48页

作者： BORELLI josé Renato GUDWIN Ricardo ribeiro 坎皮纳斯大学圣保罗联邦研究所

多用途增强认知架构(MECA)是一个旨在对“类人过程”这一跨领域复杂过程进行建模的认知框架.MECA最初专注于实施双过程理论方法,以及集成基于全局工作空间理论的机器意识机制,现已更新为集成双层包容机制,支持反应和审议行为、动态目标... 详细信息

多用途增强认知架构(MECA)是一个旨在对“类人过程”这一跨领域复杂过程进行建模的认知框架.MECA最初专注于实施双过程理论方法,以及集成基于全局工作空间理论的机器意识机制,现已更新为集成双层包容机制,支持反应和审议行为、动态目标设定和视觉空间记忆子系统,增强了其对现实世界的交互性和自适应行为能力.此外,随着对计算思想的知识表达新方案的引入,MECA提出对知识进行动态组织,以处理情景敏感推理和灵活分类.MECA的实施依赖于认知系统工具包(CST),该工具包使其可与尖端技术实现集成. MECA和CST正在不断被开发和更新、协调和开放,以纳入最新的AI器件和方法.这一举措确保了有组织、可监视、可审计和可控制的人工智能解决方案的产生,大大减少了对“黑匣子”认知过程的依赖,同时提高了受人工智能驱动的系统的透明度和可解释性.这些更新增强了MECA作为一种稳固架构的潜力,使其可用于开发能够进行现实世界交互和自适应学习,具有自主性、可适应性、情境感知的人工智能系统.

关键词：认知架构双过程理论动态包容认知系统工具包

Atypical Presentation of Crohn’s Disease: Diagnostic Challenges in a Clinical Case

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Case Reports in Clinical Medicine 2025年第1期14卷 10-14页

作者： Catarina Pinto Silva Rita Sevivas Flávia Ramos Dany Cruz Cristina Marques Beatriz Rosa Márcia ribeiro Carlos S. Oliveira Santa Maria Maior Hospital Barcelos Portugal

Introduction: Crohn’s Disease (CD) is a chronic inflammatory disorder with a heterogeneous presentation. While diarrhea, abdominal pain, and weight loss are hallmarks, atypical manifestations can obscure the diagnosis. This report highlights an unusual presentation of CD to emphasize the need for comprehensive diagnostic strategies. Case Report: A 25-year-old male presented with peripheral edema, anorexia, and abdominal distension but lacked classic gastrointestinal (GI) symptoms. Laboratory findings included microcytic anemia and hypoalbuminemia, while imaging revealed ascites and bowel wall thickening. Elevated fecal calprotectin and positive Anti-Saccharomyces cerevisiae antibodies (ASCA) supported the diagnosis. Endoscopy confirmed ileocolic Crohn’s Disease (L3 + L4). Infliximab therapy resulted in marked clinical improvement. Discussion: This case underscores the complexity of atypical CD presentations. Early use of serological markers, imaging, and endoscopy guided the diagnosis. Recognition of CD’s diverse manifestations is critical for timely intervention. Conclusion: Atypical CD presentations require heightened clinical suspicion and a multidisciplinary approach to reduce diagnostic delays and improve patient outcomes.

关键词： Crohn’s Disease Atypical Presentation Diagnostic Challenges Inflammatory Markers Infliximab Imaging

Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging

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Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.Gunn Laura Bennet Hamid Abbasi Mātai Medical Research Institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical Imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering Institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations

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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon j.Brown Rafael j.Yáñez-Muñoz Heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

Effects of the availability of floral resources and neighboring plants on nectar robbery in a specialized pollination system

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Current Zoology 2022年第5期68卷 541-548页

作者： júlia Mendonça Almeida Caio César corrêa Missagia Maria Alice Santos Alves Graduação Instituto de BiociênciasUniversidade Federal do Estado do Rio de Janeiro(UNIRIO)CEPAvenida Pasteur458Rio de Janeiro 22290-240Brazil Departamento de Ecologia Programa de Pós-Graduação em Ecologia e EvoluçãoInstituto de Biologia Roberto Alcantara Gomes(IBRAG)Laboratório de Ecologia de Aves e ComportamentoUniversidade do Estado do Rio de Janeiro(UERJ)Rua São Francisco Xavier524 Rio de JaneiroRJCEPRio de Janeiro 20550-011Brazil Departamento de Ecologia IBRAGLaboratório de Ecologia de Aves UERJ.Rua São Francisco Xavier524 Rio de JaneiroRJCEPRio de Janeiro 20550-011Brazil

Many plants pollinated by nectar-foraging animals have to maintain a balance between legitimate visitor attraction strategies and mechanisms that minimize illegitimate *** study investigated how floral display and neighboring species composition influences nectar robbing by hummingbirds in the tropical ornithophilous herb Heliconia *** tested the role of inflorescence display,flower abundance,and neighboring species in the reduction of nectar robbing in *** results indicate that nectar robbing hummingbird activity was higher in moderately large inflorescence displays and that the frequency of nectar robbing in *** decreases with increased flower abundance and the presence of neighboring plant *** non-ornithophilous plants decreased the frequency of nectar robbing in *** flowers to a greater extent than ornithophilous *** results suggest that nectar robbing hummingbirds are attracted to similar conditions that attract legitimate visitors and that spatial aggregation and mixed-species displays may represent a mechanism to dilute nectar robbing effects at an individual level.

关键词： Brazilian Atlantic forest density floral antagonists Heliconiaceae

Occurrence,leaching,and mobility of major and trace elements in a coal mining waste dump:The case of Douro Coalfield,Portugal

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Energy Geoscience 2021年第2期2卷 121-128页

作者： j.ribeiro D.Flores Department of Earth Sciences University of CoimbraRua Silvio Lima3030-790CoimbraPortugal Institute of Earth Sciences-Porto Pole Rua Do Campo Alegre 6874169-007PortoPortugal Environment and Spatial Planning Department of GeosciencesUniversity of PortoRua Do Campo Alegre 6874169-007PortoPortugal

The coal mining residues from past mining activities in the Douro Coalfield are emplaced in many dumps near the mining areas,causing substantial environmental *** study aims to contribute to the investigation of environmental impacts caused by the disposal of the residue in the Douro Coalfield through the determination of the geochemical composition of waste materials collected at 3 e 15 m depth,and of the water-leachable fraction produced by percolation in these materials inside the *** elements with higher concentration in the leachates are Ca,Cd,Co,Mg,Mn,Na,Ni,S,and Zn,indicating that they are the most easily leached and accessible elements for percolation and mobilization into the *** presence of these elements in the leachates is principally attributed to their occurrence as water-soluble ions in clays and sulphides affected by natural weathering conditions,which promotes their breakdown and occurrence as exchangeable *** leachates are classified as acid *** weathering and leaching in the Sao Pedro da Cova waste dump are the principal~paths for chemical elements to be percolated and mobilized to environment,posing risk to the soils,waters and ecosystems in the surrounding areas.

关键词： Coal mining Waste dump Water-soluble compound Hazardous element