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Neural regeneration research 2025年第3期20卷 819-820页

作者： rayudu Gopalakrishna jennifer Aguilar Emily Lee William j.Mack Department of Integrative Anatomical Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ... 详细信息

关键词： resveratrol molar dated

Scalable Ir-Doped NiFe₂O₄/TiO₂ Heterojunction Anode for Decentralized Saline Wastewater Treatment and H₂ Production

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NANO-MICrO LETTErS 2025年第1期17卷 1-18页

作者： Hong, Sukhwa Kim, jiseon Park, jaebeom Im, Sunmi Hoffmann, Michael r. Cho, Kangwoo Pohang Univ Sci & Technol POSTECH Div Environm Sci & Engn Pohang 790784 South Korea CALTECH Linde Labs Pasadena CA 91125 USA Yonsei Univ Int Campus Inst Convergence Res & Educ Adv Technol I CREATE Incheon 21983 South Korea

Wastewater electrolysis cells (WECs) for decentralized wastewater treatment/reuse coupled with H-2 production can reduce the carbon footprint associated with transportation of water, waste, and energy carrier. This study reports Ir-doped NiFe2O4 (NFI, similar to 5 at% Ir) spinel layer with TiO2 overlayer (NFI/TiO2), as a scalable heterojunction anode for direct electrolysis of wastewater with circumneutral pH in a single-compartment cell. In dilute (0.1 M) NaCl solutions, the NFI/TiO2 marks superior activity and selectivity for chlorine evolution reaction, outperforming the benchmark IrO2. robust operation in near-neutral pH was confirmed. Electroanalyses including operando X-ray absorption spectroscopy unveiled crucial roles of TiO2 which serves both as the primary site for Cl- chemisorption and a protective layer for NFI as an ohmic contact. Galvanostatic electrolysis of NH4+-laden synthetic wastewater demonstrated that NFI/TiO2 not only achieves quasi-stoichiometric NH4+-to-N-2 conversion, but also enhances H-2 generation efficiency with minimal competing reactions such as reduction of dissolved oxygen and reactive chlorine. The scaled-up WEC with NFI/TiO2 was demonstrated for electrolysis of toilet wastewater.

关键词： Wastewater electrolysis cell Ir-doped NiFe2O4 reactive chlorine species Decentralized H-2 production On-site wastewater treatment

Postoperative Crohn’s disease recurrence: A practical approach

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World journal of Gastroenterology 2008年第36期14卷 5540-5548页

作者： Pilar nos Eugeni Domènech Centro de Investigación Biomédica en red de Enfermedades Hepáticas y Digestivas (Ciberehd) Spain

Crohn's disease is a chronic inflammatory condition that may involve any segment of the gastrointestinal tract. Although several drugs have proven efficacy in inducing and maintaining disease in remission, resectional surgery remains as a cornerstone in the management of the disease, mainly for the treatment of its stenosing and penetrating complications. However, the occurrence of new mucosal (endoscopic) lesions in the neoterminal ileum early after surgery is almost constant, it is followed in the mid-term by clinical symptoms and, in a proportion of patients, repeated intestinal resections are required. Pathogenesis of postoperative recurrence (POr) is not fully understood, but luminal factors (commensal microbes, dietary antigens) seem to play an important role, and environmental and genetic factors may also have a relevant influence. Many studies tried to identify clinical predictors for POr with heterogeneous results, and only smoking has repeatedly been associated with a higher risk of POr. Ileocolonoscopy remains as the gold standard for the assessment of appearance and severity of POr, although the real usefulness of the available endoscopic score needs to be revisited and alternative techniques are emerging. Several drugs have been evaluated to prevent POr with limited success. Smoking cessation seems to be one of the more beneficial therapeutic measures. Aminosalicylates have only proved to be of marginal benefit, and they are only used in low-risk patients. Nitroimidazolic antibiotics, although efficient, are associated with a high rate of intolerance and might induce irreversible side effects when used for a long-term. Thiopurines are not widely used after ileocecal resection, maybe because some concerns in giving immunomodulators in asymptomatic patients still remain. In the era of biological agents and genetic testing, a well-established preventive strategy for POr is still lacking, and larger studies to identify good clinical, serological, and geneti

关键词： Crohn's disease Postoperative recurrence Smoking Aminosalicylates Nitroimidazolic antibiotics Thiopurines

Alpha-particle decays from excited states in ^(24)Mg

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Science China(Physics,Mechanics & Astronomy) 2011年第S1期54卷 130-135页

作者： LIOTTA r j royal Institute of Technology (KTH) AlbaNova University Center Stockholm S-10691 Sweden

Using a cluster model based on the Woods-Saxon potential, alpha-particle decays from excited states in 24Mg have been system atically investigated. Calculations can in general reproduce experimental data, noticing the fact that the preformation factor P of alpha particle in alpha-decaying nuclei is of order from 100 to 10?2. This can be the evidence for the α+20Ne structure in 24Mg. Meanwhile, the results also show the existence of other configurations, such as 16O+2α. Since the calculated decay widths are very sensitive to the angular momentum carried by the outgoing cluster (α particle), our results could serve as a guide to experimental spin assignments.

关键词： alpha decay cluster structure cluster model 24Mg

A higher-order porous thermoelastic problem with microtemperatures

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Applied Mathematics and Mechanics(English Edition) 2023年第11期44卷 1911-1926页

作者： j.r.FErNáNDEZ r.QUINTANILLA Department of Applied Mathematics I University of VigoETSI de Telecomunicacion Campus As Lagoas Marcosende s/nVigo 36310Spain Department of Mathematics Polytechnical University of CatalunyaTerrassa 08222BarcelonaSpain

In this paper,we study a porous thermoelastic problem with microtemperatures assuming parabolic higher order in time derivatives for the thermal *** model is derived and written as a coupled linear ***,a uniqueness result is proved by using the logarithmic convexity method in the case that we do not assume that the mechanical energy is positive ***,the existence of the solution is obtained by introducing an energy function and applying the theory of linear semigroups.

关键词： higher order thermoelasticity microtemperature logarithmic convexity method existence and uniqueness

Evaluation of microvascular reactivity with laser Doppler flowmetry in chronic kidney disease

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World journal of Nephrology 2013年第3期2卷 77-83页

作者： Levente Babos Zoltán járai jános Nemcsik Department of Family Medicine Semmelweis University1125 BudapestHungary Department of Cardiology St.Imre Teaching Hospital1115 BudapestHungary

Cardiovascular diseases are the major causes of mortality in patients with chronic kidney disease(CKD).The complex process of accelerated athero- and arteriosclerosis in CKD is associated with this phenomenon,where endothelial dysfunction(ED) is one of the initial steps. Hence, the early diagnosis of ED can potentially lead to early interventions which could result in a better outcome for these patients. Several methodologies have been developed for the diagnosis of ED. Laser Doppler flowmetry(LDF) enables us to study the microcirculation continuously in a non-invasive manner. In our review we would like to focus on different tests developed for LDF, like postocclusive reactive hyperaemia,local heating, iontophoresis, microdialysis or analysis of flowmotion. We would also like to summarize the available data in CKD with these methodologies to enlighten their perspectives in the clinical use on this patient population.

关键词： Chronic kidney disease Laser Doppler fowmetry Endothelial dysfunction Iontophoresis Postoc clusive reactive hyperaemia Local heating Microdialysis Flowmotion

General aspects on structural integrity

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Chinese journal of Aeronautics 2019年第1期32卷 114-132页

作者： j.j.XIONG r.A.SHENOI School of Transportation Science and Engineering Beihang University Faculty of Engineering and Environment University of Southampton

This paper seeks to mark the fruitful collaborative research between scholars in the University of Southampton and Beihang University for last 25 years on structural integrity. Their efforts addressed some important issues in structural integrity such as fatigue and fracture behavior,fatigue load spectra, fatigue and fracture lifetimes, reliability-based service period, adhesively bonded composite patch repairs, Plain Woven Fabric(PWF) composites and composite *** advances in engineering approaches, experimental methods, numerical algorithms and understanding of failure mechanisms relating to structural integrity are highlighted. Probable limits(or drawbacks) are also discussed. This review provides an insight into the general aspects on structural integrity and constitutes a basis for pointers to the further works on structural integrity.

关键词： Composites Fatigue Fracture reliability repair Structural integrity

Hazards and Landscape Changes(Degradations) on Hungarian Karst Mountains Due to Natural and Human Effects

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journal of Mountain Science 2013年第1期10卷 16-28页

作者： Móga jnos Kiss KLAUDIA Szabó MrIA Kériné Borsodi ANDrEA Kéri ANDrS Mari LSZLó Knáb MóNIKA Iván VErONIKA Geography and Earth Science Institute Etvs Loránd University Biology Institute Etvs Loránd University

In order to study the karstological processes within the karst ecological system,the geohazards and degradation of karst landscapes on the karst areas of the Bakony mountains(Hungary),we investigated the abiotic elements of the environment,soil and cover deposits,erosion soil decay;the changes in the quantity and quality of karst waters:contamination at swallow holes,contamination of karst springs;and the biogenic factors:surface vegetation coverage by the corine land cover method,plant-ecological examinations,qualification of surface waters with the help of biological water *** recognized that the increasing human activities during the past few centuries have had significant impact on the investigated landscapes of karst areas because of their spatial *** the scope of our research we concluded that the landscape changes due to natural and human effects can vary strongly on the different karst *** differences can arise from the climatic and geomorphologic situation,the coverlayer's qualities,etc.,but primarily from the different utilization of the investigated karst areas(*** intensity,characteristics and territorial extension of utilization).On the spot investigation we detected traces of new and fast geomorphological processes(gully formation,landslides,collapses,new sinkhole development) and landforms(sinkholes,gullies,swallow holes),which are clear evidences of the effect of climatic changes.

关键词： Karst landscape Geological hazards Soil erosion Limestone mountain

Context-dependency in medicine:how neuronal excitability influences the impact of dopamine on cognition

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Neural regeneration research 2025年第11期20卷 3225-3226页

作者： Mahboubeh Ahmadi Nahid rouhi javad Mirnajafi-Zadeh Bechara j.Saab Department of Physiology Faculty of Medical SciencesTarbiat Modares UniversityTehranIran Mobio Interactive Pte.Ltd. SingaporeRepublic of Singapore

Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain *** dopamine is primarily associated with pleasure,reward,and motivation,its effects can be quite complex;and this complexity is further compounded when examining how dopamine functions in typical versus disease-affected neural *** pa rticula r,epilepsy,characte rized by heightened brain excitability,is linked to cognitive dysfunction,and dopamine is implicated in elements of both its pathology and *** has been successful in describing the synaptic abnormalities believed to contribute to memory issues in epilepsy,aiding in the search for effective therapies for what persists as a major medical issue.

关键词： dopamine epilepsy primarily

Brain-penetrating neurotrophic factor mimetics: HEr-096 as a disease-modifying therapy for Parkinson’s disease

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Neural regeneration research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira M.Holmström Henri j.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic