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Digestibility,Antioxidant and Anti-Inflammatory Activities of Pecan nutshell(Carya illioinensis)Extracts

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Journal of Renewable Materials 2022年第10期10卷 2569-2580页

作者： María Janeth Rodríguez-Roque Carmen Lizette Del-Toro-Sánchez Janet Madeline Chávez-Ayala Ricardo iván gonzález-Vega Liliana Maribel Pérez-Pérez Esteban Sánchez-Chávez nora AideéSalas-Salazar Juan Manuel Soto-Parra Rey David Iturralde-García María Antonia Flores-Córdova Facultad de Ciencias Agrotecnológicas Universidad Autónoma de ChihuahuaChihuahuaMéxico Universidad de Sonora Rosales y Niños Héroes S/NHermosilloSonMéxico Centro de Investigación en Alimentación y Desarrollo A.C.Unidad DeliciasDeliciasChihuahuaMéxico

Phenolic compounds are related to high biological activity,avoiding oxidation in food and human *** are by-products derived from the pecan nut processing that contain important amounts of phenols which biological activity must be *** research aimed to evaluate the antioxidant(DPPH,ABTS,FRAP and hemolysis)and anti-inflammatory activities of shell extracts from pecan nuts harvested during the crop production cycle 2018 and 2019,as well as the in vitro digestibility of their phenolic compounds,including *** showed that extracts from the crop production cycle 2018 obtained the highest yield,while those from 2019 contained the highest concentration of phenolic compounds,flavonoids and antioxidant capacity determined by DPPH(22.96 mmol ET),ABTS(91.55 mmol ET)and inhibition of hemolysis(92.12%).The anti-inflammatory activity exhibited an inhibition of the elastase enzyme up to 50 min and the bioaccessibility of phenolic compounds reached up to 32%.These results showed that pecan nutshell extracts are an important source of biologically active compounds,thus,they are suitable to be used as commodities in different fields such as agricultural,food and pharmaceutical *** studies must be carried out in order to elucidate the activity of nutshell extracts within in vivo systems.

关键词： Anti-inflammatory activity antioxidants digestibility shell phenolic compounds

Pyonephrosis as a sign of sarcomatoid carcinoma of the renal pelvis

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世界临床病例杂志 2014年第6期2卷 215-218页

作者： Sergio Fernández-Pello Victoria Venta iván gonzález Rodrigo Gil Carmen Luz Menéndez Department of Urology Cabuenes Hospital33394 GijonSpain Department of Pathology Cabuenes Hospital33394 GijonSpain

We report the case of an urgent nephrectomy because of a pyonephrosis and sepsis due to an unsuspected sarcomatoid transitional cell carcinoma, an infrequent subtype with a bad oncological prognosis. We present a 58-year-old man assessed by internal medicine for a general syndrome and weakness many months previously. A pyonephrotic kidney was observed at abdominal computed tomography in the context of septic shock, without suspecting the underlying cause. The pathology report described a sarcomatoid transitional cell carcinoma. Sarcomatoid transitional cell carcinoma is an invasive and infrequent subtype of urothelial tumors. The symptoms are often the same as other renal masses; however, in this case, sepsis and pyonephrosis were the rare initial symptoms.

关键词： Urothelial carcinoma Renal pelvis Sarcomatoid

MicroRnAs dysregulation in hepatocellular carcinoma: Insights in genomic medicine

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World Journal of Hepatology 2015年第11期7卷 1530-1540页

作者： iván Lyra-gonzález Laura E Flores-Fong Ignacio gonzález-García David Medina-Preciado Juan Armendáriz-Borunda Departamento de Biología Molecular y Genómica CUCS Universidad de Guadalajara Instituto de Biología Molecular en Medicina y Terapia Génica O.P.D. Hospital Civil de Guadalajara "Fray Antonio Alcalde" O.P.D. Hospital Civil de Guadalajara "Juan I. Menchaca" Departamento de Biología Molecular y Genómica CUCS Universidad de Guadalajara

Hepatocellular carcinoma(HCC) is the leading primary liver cancer and its clinical outcome is still poor. MicroRnAs(mi RnAs) have demonstrated an interesting potential to regulate gene expression at post-transcriptional level. Current findings suggest that mi RnAs deregulation in cancer is caused by genetic and/or epigenetic, transcriptional and post-transcriptional modifications resulting in abnormal expression and hallmarks of malignant transformation: aberrant cell growth, cell death, differentiation, angiogenesis, invasion and metástasis. The important role of mi RnAs in the development and progression of HCC has increased the efforts to understand and develop mechanisms of control overt this single-stranded RnAs. Several studies have analyzed tumoral response to the regulation and control of deregulated mi RnAs with good results in vitro and in vivo, proving that targeting aberrant expression of mi RnAs is a powerful anticancer therapeutic. Identification of up and/or down regulated mi RnAs related to HCC has led to the discovery of new potential application for detection of their presence in the affected organism. Mi RnAs represent a relevant new target for diagnosis, prognosis and treatment in a wide variety of pathologic entities, including HCC. This manuscript intends to summarize current knowledge regarding mi RnAs and their role in HCC development.

关键词： Hepatocellular carcinoma MicroRnAs Regulation Therapeutic targets

Pancreatic Pseudocyst Rupture: Cause of Acute Abdomen

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Case Reports in Clinical Medicine 2023年第8期12卷 324-331页

作者： Joel iván Cruz-gonzález Miguel Ángel Miranda-Del Olmo Benito Antonio García-Ramón Brenda Hernández-García Crystell Guadalupe Guzmán-Priego Alejandro Jiménez-Sastré Social Security Institute of the State of Tabasco Villahermosa Mexico Cardiometabolism Laboratory Academic Division of Health Sciences Juarez Autonomous University of Tabasco Villahermosa Mexico

Case report of a 23-year-old male patient with a pancreatic pseudocyst, initially was treated by the Interventional Radiology service by placing percutaneous drainage with poor evolution, abruptly presented abdominal pain, Systemic Inflammatory Response Syndrome and peritoneal irritation, so an urgent exploratory laparotomy was performed with a finding of rupture of the pancreatic pseudocyst into the abdominal cavity. He presented septic shock and died in the immediate postoperative period. Computerized Axial Tomography represents the ideal diagnostic method. Spontaneous rupture is extremely rare and requires urgent surgical intervention.

关键词： Rupture Pancreatic Pseudocyst Acute Abdomen

Copper Oxide Inked with Dye Obtained from the Lactarius Indigo Fungus for Energy Production

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Journal of Materials Science and Chemical Engineering 2022年第11期10卷 36-51页

作者： Abigail Bautista Castañeda Maria Guadalupe Montes De Oca Dulce Yolotzin Medina Velazquez Jorge iván Aldana gonzález Pedro Adrian Martinez Montolla Joan Reyes Miranda Miguel Angel Barron Universidad Autónoma Metropolitana Departamento de Materiales Ciencias Básicas e Ingeniería Reynosa Tamaulipas México Instituto Politécnico nacional ESIQIE UPALM S/N Col. Mexico City México

The results obtained from the characterization of a copper deposit on indium doped tin oxide (ITO), inked with natural dye extracted from the Lactarius indigo fungus, for use in Gratzel type solar cells are reported. An electrolyte composed of 0.1 M HnO3 and 0.5 M CuSO4 was used, this solution was prepared for copper deposits on the ITO. Cyclic voltammetry was performed at different scan rates to obtain the reduction zone for deposition between potentials of ?100 to ?500 mV. The dye was obtained from the indigo Lactarius fungus from maceration, once the inked deposits were obtained, characterizations were performed, the initial test was to obtain the Ultraviolet-Visible (UV-visible) of the pure dye, and later the same test was performed on the inked oxide. Electrochemical Impedance Spectroscopy (EIS) was performed on the samples, as well as Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM), to characterize the material properties for its application.

关键词： Copper Oxide Ink Dye Energy Production Indigo Milk Mushroom

Influence of biomass burning on ozone levels in the Megalopolis of Central Mexico during the COVID-19 lockdown

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Journal of Environmental Sciences 2024年第9期143卷 99-115页

作者： Victor Almanza Luis Gerardo Ruiz-Suárez Ricardo Torres-Jardón Agustín García-Reynoso iván Y.Hernández-Paniagua Institute for Atmospheric Sciences and Climate Change National Autonomous University of MexicoCoyoacan 04510Mexico CityMexico

The massive reductions in anthropogenic emissions resulting from the COVID-19 lockdown provided a unique opportunity to evaluate the effect of mitigation measures aiming to abate air *** Mexico,the total lockdown period took place during the dry-hot season when biomass burning activity is ***,we investigate the role of biomass burning emissions on regional ozone levels in the Megalopolis of Central *** studied period covers the lockdown phases 2 and 3,and the first month of the new *** applied a factor separation technique and process analysis to estimate the pure and synergistic contributions of emission reductions under lockdown and that from biomass burning to daily ozone maximum concentrations in 7 metropolitan areas of different states in the *** results revealed that biomass burning plumes likely masked the effect of massive reductions from mobile emissions,impacted the PBL development during phase 3 and favored transition and mixed nO_(x)-limited and VOC-limited regional *** contributed to increased ozone production in the middle to lower PBL by changing the regional background levels which potentially could bias high ozone production efficiency *** the Megalopolis contribution to economic and societal development at national scale,our study suggests that ozone mitigation measures during the dry-hot season targeting mainly mobile emissions will likely be offset by biomass burning plumes.A regional and synergic policy aiming to control biomass burning would help to reduce the occurrence of high ozone levels in Central Mexico with the co-benefit of tackling short-lived climate pollutants.

关键词： COVID-19 Mexico Megalopolis Ozone Factor Separation Process Analysis

Technical efficiency of cocoa farms at varying elevation levels in Davao City, Philippines: implications to sustainable upland farming systems

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Journal of Mountain Science 2024年第1期21卷 33-48页

作者： Francis Levi A.DURAnO Jon Marx SARMIEnTO Larry n.DIGAL Pedro A.ALVIOLA iv School of Management University of the Philippines MindanaoDavao City 8000Philippines

Elevation is one of many components that influence agriculture, and this in turn affects the level of both inputs and outputs of farmers. This article focuses on the productivity and technical efficiency of 100 cocoa farms using cross-sectional data from areas ranging from 190 to 1021 m above sea level which were classified as low, medium, and high elevation in Davao City, considered as the chocolate capital of the Philippines. Using stochastic frontier analysis, the results showed that the cost of inputs per ha and the number of cocoa trees per ha significantly increase yield. Farms at high elevations were less technically efficient, as this entails lower temperatures and increased rainfall, and cocoa farming in those areas and conditions can be more challenging, especially with changes in farming practices, terrain, and distance to markets. Other significant variables were age of cocoa farms, married farmers, and age of the farmers. Older farms may be more developed, farmers who are married benefit from their spouses being able to readily contribute as farm labor, and lastly, older farmers' inefficiency may likely stem from nonadaptation of newer farming practices. With an average technical efficiency of 0.61, 0.63, and 0.26 in low, medium, and high elevation areas, respectively, farmers therefore have an incentive to improve farm practices and consider topographical variations found in high elevation areas. Recommendations for the improvement of technical efficiency of cocoa farms are better connectivity to markets, enhancing farm practices, and continuation and improvement of government programs on cocoa with an added emphasis on research. For farmers in high elevation areas, mitigating solutions such as sustainable agriculture practices and ecolabelling are key to improving efficiency and minimizing the potential negative impact on upland farming systems. Moreover, such adaptation measures may also contribute to sustainability of cocoa farming in high elevation

关键词： Cocoa farms Cobb-Douglas production function Elevation Philippines Stochastic frontier analysis Technical efficiency

Mental health in organizations from a healthcare analytics framework:taxonomic model,trends,and impact of COVID-19

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Journal of Management Analytics 2024年第1期11卷 62-86页

作者： Jorge iván Pérez Rave Carlos Mario Zapata Jaramillo Gloria Patricia Jaramillo Álvarez IDInnOV research group IDINNOV S.A.SMedellínColombia Department of Computing and Decision Sciences Universidad Nacional de ColombiaMedellínColombia

Mental disorders negatively affect employee well-being and organizational *** face a challenge in terms of how to manage mental *** paper clarifies three issues(underlying patterns,trends,and impact of COVID-19)regarding the scientific study of mental health in organizations from a healthcare analytics *** framework comprises eight stages considering a text-driven approach with scientific corpora assisted by linguistic/computational and statistical *** study discovers a new taxonomic model comprising five patterns in the scientific discourse on the *** analyses reveal imbalances and concerns regarding the interests associated with the patterns,which is reinforced by examining patterns“before”and“during”*** paper complements psychological/epidemiological studies on mental health in organizations from a healthcare analytics perspective.

关键词： Healthcare analytics healthcare management analytics mental health scientific discourse text analytics taxonomy COVID-19 management analytics

nutritional Supplement Ocoxin® Combined with Gemcitabine-Based Chemotherapy in Patients with Advanced Pancreatic Adenocarcinoma

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Open Journal of Gastroenterology 2024年第8期14卷 267-287页

作者： Mayté Lima-Pérez Jorge Luis Soriano-García Masiel gonzález-Meisozo Jorge Luis Soriano-Lorenzo Vilma Fleites-Calvo Dunia Morales-Morgado Carlos Domínguez-Álvarez iván Ramón-Concepción Raidel Rodríguez-Barrios Alicia Tarinas-Reyes ivis Mendoza-Hernández Rolando Uranga-Piña Clinical Oncology Department Ameijeiras Hospital Havana Cuba Clinical Pathology Department Ameijeiras Hospital Havana Cuba Clinical Section National Coordinating Centre for Clinical Trials Havana Cuba Biostatistics Section National Coordinating Centre for Clinical Trials Havana Cuba

Background: the quality of life (QoL) of patients with pancreatic ductal adenocarcinoma (PDAC), with its limited survival, can be affected by chemotherapy-induced toxicity. The main objective was to evaluate the effect of introducing ocoxin oral solution (OOS) in combination with standard therapy on quality of life. Methods: Thirty patients were enrolled in an exploratory, prospective, single-centre clinical trial in the oncology department of “Hermanos Ameijeiras” University Hospital in Havana, Cuba. Quality of life was measured using the EORTC QLQ-C30 questionnaire and toxicity was assessed using the nCI-CTC-AE classification version 5.0. Results: There was stability in the scores over time for overall QoL and the functional scale criteria, while in terms of symptoms, fatigue, pain and loss of appetite were reduced. no grade 3 - 4 adverse events (AEs) were recorded, and only 14.9% of toxicities were classified as grade 2, and these were considered to be unrelated to OOS. Biochemical and nutritional parameters were normalised at 12 months compared to the baseline values. Conclusions: This clinical study is the first report of the use of OOS in patients with advanced pancreatic cancer, and demonstrates that it is able to maintain optimal quality of life with reduced severity of toxicity during and after combination treatment with gemcitabine-based chemotherapy.

关键词： EORTC QLQ-C30 Ocoxin Chemotherapy Pancreatic Cancer Quality of Life