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Segmentation of thermal infrared images of cucumber leaves using K-means clustering for estimating leaf wetness duration

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International Journal of Agricultural and Biological Engineering 2020年第3期13卷 161-167页

作者： Dongmei Wen Aixin Ren Tao Ji isabel maria flores-parra Xinting Yang Ming Li Beijing Research Center for Information Technology in Agriculture/National Engineering Research Center for Information Technology in Agriculture/National Engineering Laboratory for Agri-product Quality Traceability/National Meteorological Service Center of Urban Agriculture Beijing 100097China College of Plant Protection China Agricultural UniversityBeijing 100193China Department of Sustainable Crop Production UniversitàCattolica del Sacro Cuore29122 PiacenzaItaly Department of Informatics University of AlmeriaAlmeriaCP04120Spain

Leaf wetness duration(LWD)is a critical parameter used to predict plant disease,but its determination under actual field conditions is a major *** this study,a method for determining LWD using thermal infrared imaging was developed and applied to cucumber plants grown in a solar *** images of the plant leaves were captured using an infrared scanning camera,and a leaf wetness area segmentation method consisting of two procedures was ***,a color space conversion was performed automatically by an image-processing ***,the K-means clustering algorithm was applied to enable the segmentation of the wetness area on the thermal ***,to enable overall thermal image analysis,an initial leaf wetness threshold(LWT)of 5%was defined(where wetness values higher than 5%indicated that the leaf was in a wet state).The results of comparative experiments conducted using thermal images of plant leaves captured using an infrared scanning camera and human visual observation indicated that the estimated LWD values were generally higher than the observed LWD values,because slight leaf wetness condensations were overlooked by the human eye but detected by the infrared scanning *** these differences were not found to be statistically significant in this study,the proposed method for determining LWD using thermal infrared imaging may provide a new LWD detection method for cucumber and other plants grown in solar greenhouses.

关键词： thermal imaging K-means clustering algorithm leaf wetness duration cucumber

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Remediation of amide pesticide-polluted soils by combined solarization and ozonation treatment

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Pedosphere 2024年第3期34卷 641-651页

作者： isabel GARRIDO Carmen MMARTINEZ Pilar flores Pilar HELLIN Fulgencio CONTRERAS Jose FENOLL Department of Sustainability and Quality Group of Fruit and Vegetable Products Instituto Murciano de Investigacion y Desarrollo Agrario y MedioambientalLa Alberca 30150(Spain)

Agriculture has a close relationship with nature,but it can also be the source of negative and permanent environmental *** use of pesticides in modern agriculture is a common practice,but their side effects on the environment cannot be *** this study,we evaluated a combination of solarization and ozonation techniques for the elimination of six amide pesticides(boscalid,chlorantraniliprole,cyflufenamid,fluopyram,napropamide,and propyzamide)in *** experiments were performed with four different soils to assess the efficiency of this methodology at different soil temperatures and ozone dosages under laboratory conditions,and then a greenhouse pot experiment was conducted under controlled conditions during *** days after the onset of the experiments,higher degradation percentages of amide pesticides were observed in ozonized soils than in other treated soils,particularly when ozone was applied at 10 cm soil *** results show that the utilization of ozonation,along with solarization,represents a valid method for degrading residues of the studied pesticides and suggest that this combined technology may be a promising tool for remediating pesticide-polluted soils.

关键词： intermediate ozone pesticide degradation pesticide residue polyethylene film remediation technique

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XEN^(■) implant and trabeculectomy medium-term quality of life assessment and comparison of results

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International Journal of Ophthalmology(English edition) 2018年第12期11卷 1941-1944页

作者： Ana Luisa Basilio Nuno Moura-Coelho Ines Passos mariana Sa Cardoso isabel Domingues maria Reina Rita flores Teresa Gomes Ophthalmology Department Central Lisbon Hospital Center Lisbon 1169050Portugal

AIM: To evaluate and compare the quality of life of patients submitted to XEN~? implant or trabeculectomy and the relationship with potentially involved ***: A cross-sectional study of patients with advanced open-angle glaucoma who underwent implantation of XEN~?(group 1) and trabeculectomy(group 2) between October 2015 and February 2017. The studied variables were: age, gender, follow-up time, need of topical anti-hypertensive therapy, visual acuity and intraocular pressure(IOP). The quantification of the quality of life was attained through the Glaucoma Symptom Scale(GSS) questionnaire. RESULTS: Totally 34 eyes(34 patients) were included, 17 in each group. The mean GSS scores for group 1 were 42.6±6.8(median, 47; p25, 36.5; p75, 48.5) and for group 2 it was 41.6±7.0(median, 43; p25, 36.5; p75, 47.0; P=0.34). There was a strong negative correlation between the need for topical anti-hypertensive drugs and the GSS result in both groups(r=-0.88, P<0.01, r=-0.59, P=0.01, respectively) and a moderate negative correlation with IOP in group 1(r=-0.50, P=0.03).CONCLUSION: The analysis demonstrates the noninferiority of medium-term quality of life of one group in relation to the other(XEN~? implant and trabeculectomy). The number of topical anti-hypertensive drugs and IOP negatively influenced the quality of life.

关键词： quality of life XEN^(■) trabeculectomy

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Inclusive Intergenerational Experiences With Elderly and Minor People： A New Horizon for Inclusion？

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Sino-US English Teaching 2018年第2期15卷 102-107页

作者： maria Jose flores Tena Silvia isabel Vallejo Jimenez Professor at the Autonomous University of Madrid Department of Theory and Didactics of Education Works at Alcobendas City Council Spain

The research presents the progressive increase of lifelong education and its influence on the paradigm of socio-educational inclusion. Today＇s society is characterized by its increasing aspiration and demand for activities of social promotion and personal development, that is, activities that tend to reinforce the social fabric in its human and community values, in the elimination of loneliness, or increasing the quality of life, through the full enjoyment of civic rights, common cultural property, or participation in the opportunities offered by public and community life The older population has transformed their habits, integrating new values generated by social changes. In turn, it leads to possible changes in social intervention. These include training, leisure, tourism, social skills development, the use of the Internet as a tool for knowledge and communication, and social participation. These new social behaviors can be an opportunity to build a more cohesive and supportive society, without generational breaches And this line, the attention to diversity and its even processes seeks to expand its reach, generating intergenerational spaces

关键词： education lifelong learning inclusion intergenerational approach competences active madco-responsible citizenship

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Therapy with stem cells in inflammatory bowel disease

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World Journal of Gastroenterology 2014年第5期20卷 1211-1227页

作者： María del Pilar Martínez-Montiel Gonzalo Jesús Gómez-Gómez Ana isabel flores IBD Unit Department of Gastroenterology Universitary Hospital 12 Octubre Medicine Regenerative Group Investigation Center 12 Octubre Investigation Institute

Inflammatory bowel disease (IBD) affects a part of the young population and has a strong impact upon quality of life. The underlying etiology is not known, and the existing treatments are not curative. Furthermore, a significant percentage of patients are refractory to therapy. In recent years there have been great advances in our knowledge of stem cells and their therapeutic applications. In this context, autologous hematopoietic stem cell transplantation (HSCT) has been used in application to severe refractory Crohn’s disease (CD), with encouraging results. Allogenic HSCT would correct the genetic defects of the immune system, but is currently not accepted for the treatment of IBD because of its considerable risks. Mesenchymal stem cells (MSCs) have immune regulatory and regenerative properties, and low immunogenicity (both autologous and allogenic MSCs). Based on these properties, MSCs have been used via the systemic route in IBD with promising results, though it is still too soon to draw firm conclusions. Their local administration in perianal CD is the field where most progress has been made in recent years, with encouraging results. The next few years will be decisive for defining the role of such therapy in the management of IBD.

关键词： Mesenchymal stem cell, Inflammatory bowel disease, Crohn’ s disease, Ulcerative colitis, Haematopoietic stem cell transplantation

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Graphene oxide/multi-walled carbon nanotubes/gold nanoparticle hybridfunctionalized disposable screen-printed carbon electrode to determine Cd(II)and Pb(II)in soil

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International Journal of Agricultural and Biological Engineering 2019年第3期12卷 194-200页

作者： Hui Wang Yuan Yin Guo Zhao Fernando Bienvenido isabel M.flores-parrad Zhiqiang Wang Gang Liu Key Laboratory of Modern Precision Agriculture System Integration Research Ministry of Education and Key Laboratory of Agricultural Information Acquisition TechnologyMinistry of AgricultureChina Agricultural UniversityBeijing 100083China Department of Informatics University of AlmeriaAlmeriaSpain College of Computer Science and Technology Shandong University of TechnologyZibo 255049China Research Institute of Wood Industry Chinese Academy of ForestryBeijing 100091China

Cadmium(Cd)and lead(Pb)in soil or water environment cause the ecological destruction and environmental deterioration when their contents exceed the natural background *** trace the concentrations of Cd(II)and Pb(II),a sensitive and selective electrode was developed using disposable screen-printed carbon electrode(SPE)immobilized with a composite film of reduced graphene oxide/carboxylation multi-walled carbon nanotubes/gold nanoparticle hybrid(RGO-MWNT-AuNP)throughπ-π*** highly conductive nano-composite layer,“RGO-MWNT-AuNP,”was characterized by scanning electron microscopy,UV-visible spectrometer,cyclic voltammetry,and electrochemical impedance *** wave stripping voltammetry was applied to RGO-MWNT-AuNP/SPE to electroplate bismuth film and monitor the Cd(II)and Pb(II)*** obtain high current responses,the detecting parameters were *** optimized conditions,the current responses showed a linear relationship with the concentrations of Cd(II)and Pb(II)in the range from 1.0 to 80.0μg/L with a lower detection limit of 0.7μg/L and 0.3μg/L(S/N=3),***,the prepared electrode was further employed to detect Cd(II)and Pb(II)in soil samples with good results.

关键词： electrochemical electrode heavy metal contamination screen-printed carbon electrode graphene gold nanoparticle lead cadmium multi-walled carbon nanotube

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Strain-induced band gap engineering in layered TiS3

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Nano Research 2018年第1期11卷 225-232页

作者： Robert Biele Eduardo flores Jose Ramon Ares Carlos Sanchez isabel J. Ferrer Gabino Rubio-Bollinger Andres Castellanos-Gomezs Roberto D'Agosta Nano-Bio Spectroscopy Group and European Theoretical Spectroscopy Facility (EFSF) Universidad del Pals Vasco 20018 San Sebastidn Spain Materials of Interest in Renewable Energies Group (MIRE Group) Dpto. de Fisica de Materiales Universidad Aut6noma de Madrid 28049 Madrid Spain Instituto de Ciencia de Materiales "Nicolds Cabrera" Campus de Cantoblanco 28049 Madrid Spain Dpto. de Ffsica de la Materia Condensada Condensed Matter Physics Center (IFIMAC) Universidad Aut6noma de Madrid Campus de Cantoblanco 28049 Madrid Spain Instituto de Ciencia de los Materiales de Madrid (ICMM-CSIC) Cantoblanco 28049 Madrid Spain IKERBASQUE Basque Foundation for Science 48013 Bilbao Spain

By combining ab initio calculations and experiments, we demonstrate how the band gap of the transition metal trichalcogenide TiS3 can be modified by inducing tensile or compressive strain. In addition, using our calculations, we predicted that the material would exhibit a transition from a direct to an indirect band gap upon application of a compressive strain in the direction of easy electrical transport. The ability to control the band gap and its nature could have a significant impact on the use of TiS3 for optical applications. We go on to verify our prediction via optical absorption experiments that demonstrate a band gap increase of up to 9% （from 0.99 to 1.08 eV） upon application of tensile stress along the easy transport direction.

关键词： band gap engineering titanium trisulfide 2-D materials strain

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Impact of HIV on the health-related quality of life in youth with perinatally acquired HIV

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World Journal of Pediatrics 2019年第5期15卷 492-498页

作者： isabel Cuéllar-flores Talís Saínz Carlos Velo María isabel González-Tomé Cristina García-Navarro Caroclina Fernández-Mcphee Sara Guillén JoséTomás Ramos Pilar Miralles Rafae Rubio JoséIgnacio Bernardino Luis Prieto Pablo Rojo Santiago Jiménez de Ory maria Luisa Navarro CoRiSpe(FARO and NeuroCoRISpeS projects,RITIP-Traslational Research Network in Pediatric Infectious Diseases) Pediatric Department Hospital Clínico San CarlosMadridSpain Infectious Diseases Service Paed DepartmentHospital La PazMadridSpain La Paz Research Institute(IdiPAZ) MadridSpain Infectious Diseases Service Paed DepartmentHospital 12 de OctubreMadridSpain Infectious Diseases Service Paed DepartmentH.Gregorio MaranónMadridSpain Paed Department Hospital de GetafeMadridSpain Infectious Diseases Service H.Gregorio MaranónMadridSpain HIV Service Hospital 12 de OctubreMadridSpain Infectious Diseases Service Hospital La PazMadridSpain Instituto de Investigación Sanitaria Hospital Gregorio Maranón(IiSGM) MadridSpain Universidad Complutense de Madrid MadridSpain Translational Research Network in Pediatric Infectious Diseases(RITIP) MadridSpain 不详

Background Studies investigating health-related quality of life(HRQoL)in youth with perinatally acquired HIV(PHIV+)are *** study aimed to compare HRQoL of PHIV+to sociodemographic-matched youth not living with HIV(HIV-),Spanish general youth population,and to explore associations between sociodemographic variables,drug consumption,and *** PHIV+youth were randomly selected from CoRISpe database(Cohort of the Spanish Pediatric HIV Network).HRQoL was evaluated by *** Thirty-nine PHIV+youth(mean age:23.36 years,SD=3.83)and thirty-nine HIV-youth(mean age:22.97 years,SD=3.80)participated in this ***+obtained lower scores in SF-12 physical health subscale(PCS)than HIV-(P=0.001)and Spanish general youth population(P=0.006).PHIV+had lower scores on the mental health subscale(MCS)than the Spanish general youth population(P<0.001).PHIV+who were at school obtained better scores than those were not at ***+youth who had used cocaine and cannabis had lower scores in MCS(P=0.002).Conclusions There is a need for HRQoL management in the associated medical follow-up.

关键词： Drug consumption Health-related quality of life Mental health Perinatally acquired HIV youth

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Neuroprotective effect of immunomodulatory peptides in rats with traumatic spinal cord injury

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Neural Regeneration Research 2021年第7期16卷 1273-1280页

作者： Dulce parra-Villamar Liliana Blancas-Espinoza Elisa Garcia-Vences Juan Herrera-García Adrian flores-Romero Alberto Toscano-Zapien Jonathan Vilchis Villa Rodríguez Barrera-Roxana Soria Zavala Karla Antonio Ibarra Raúl Silva-García Unidad de Investigación Médica en Inmunología Hospital de PediatríaCentro Médico Nacional Siglo XXI/Instituto Mexicano del Seguro Social/Ciudad de MéxicoMéxico Centro de Investigación en Ciencias de la Salud(CICSA) Facultad de Ciencias de la SaludUniversidad Anáhuac MéxicoCampus NorteHuixquilucanEdo de MéxicoMéxico Centro de Investigación del Proyecto Camina A.C Ciudad de MéxicoMéxico

Several therapies have shown obvious effects on structural conservation contributing to motor functional recovery after spinal cord injury(SCI).Nevertheless, neither strategy has achieved a convincing *** purposed a combined therapy of immunomodulatory peptides that individually have shown significant effects on motor functional recovery in rats with *** objective of this study was to investigate the effects of the combined therapy of monocyte locomotion inhibitor factor(MLIF), A91 peptide, and glutathione monoethyl ester(GSH-MEE) on chronic-stage spinal cord *** Sprague-Dawley rats underwent a laminectomy of the T9 vertebra and a moderate *** groups were included: sham, PBS, MLIF + A91, MLIF + GSH-MEE, A91 + GSH-MEE, and MLIF + A91 + *** months after injury, motor functional recovery was evaluated using the open field *** and white matter preservation was evaluated using hematoxylin & eosin staining and Luxol Fast Blue staining, *** number of motoneurons in the ventral horn and the number of axonal fibers were determined using hematoxylin & eosin staining and immunohistochemistry, *** deposition was evaluated using Masson's trichrome *** combined therapy of MLIF, A91, and GSH-MEE greatly contributed to motor functional recovery and preservation of the medullary parenchyma, white matter, motoneurons, and axonal fibres, and reduced the deposition of collagen in the lesioned *** combined therapy of MLIF, A91, and GSH-MEE preserved spinal cord tissue integrity and promoted motor functional recovery of rats after *** study was approved by the National Commission for Scientific Research on Bioethics and Biosafety of the Instituto Mexicano del Seguro Social under registration number R-2015-785-116(approval date November 30, 2015) and R-2017-3603-33(approval date June 5, 2017).

关键词： glutathione monoethyl ester monocyte locomotion inhibitor factor motor functional recovery neuroprotection neurorestoration peptides protective autoimmunity spinal cord injury

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The human olfactory system in two proteinopathies: Alzheimer’s and Parkinson’s diseases

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Translational Neurodegeneration 2020年第2期9卷 270-289页

作者： isabel Ubeda-Bañon Daniel Saiz-Sanchez Alicia flores-Cuadrado Ernesto Rioja-Corroto Melania Gonzalez-Rodriguez Sandra Villar-Conde Veronica Astillero-Lopez Juan Pablo Cabello-de la Rosa maria Jose Gallardo-Alcañiz Julia Vaamonde-Gamo Fernanda Relea-Calatayud Lucia Gonzalez-Lopez Alicia Mohedano-Moriano Alberto Rabano Alino Martinez-Marcos Neuroplasticity and Neurodegeneration Laboratory Ciudad Real Medical SchoolCRIBUniversity of Castilla-La Mancha13005Ciudad RealSpain Neurology Service Ciudad Real General University Hospital13005Ciudad RealSpain Pathology Service Ciudad Real General University Hospital13005Ciudad RealSpain Faculty of Health Sciences University of Castilla-La ManchaTalavera de la ReinaSpain Neuropathology Department and Tissue Bank CIEN FoundationCarlos III Health InstituteMadridSpain

Alzheimer’s and Parkinson’s diseases are the most prevalent neurodegenerative *** etiologies are idiopathic,and treatments are symptomatic and orientated towards cognitive or motor ***,both are proteinopathies with pathological aggregates(plaques of amyloid-β peptide and neurofibrillary tangles of tau protein in Alzheimer’s disease,and Lewy bodies mostly composed of α-synuclein in Parkinson’s disease).These deposits appear in the nervous system in a predictable and accumulative sequence with six neuropathological *** disorders present a long prodromal period,characterized by preclinical signs including ***,the olfactory system,particularly the anterior olfactory nucleus,is initially and preferentially affected by the *** atrophy revealed by magnetic resonance imaging must be complemented by histological analyses to ascertain whether neuronal and/or glial loss or neuropil remodeling are responsible for volumetric *** has been proposed that these proteinopathies could act in a prion-like manner in which a misfolded protein would be able to force native proteins into pathogenic folding(seeding),which then propagates through neurons and glia(spreading).Existing data have been examined to establish why some neuronal populations are vulnerable while others are resistant to pathology and to what extent glia prevent and/or facilitate proteinopathy *** approaches reveal a number of hubs in the olfactory system(anterior olfactory nucleus,olfactory entorhinal cortex and cortical amygdala)that are key interconnectors with the main hubs(the entorhinal–hippocampal–cortical and amygdala–dorsal motor vagal nucleus)of network dysfunction in Alzheimer’s and Parkinson’s diseases.

关键词： α-Synuclein Amyloid-β Anterior olfactory nucleus Hyposmia Tau protein

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