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Endoscopic ultrasound sedation in the United Kingdom: Is life without propofol tolerable?

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World Journal of Gastroenterology 2017年第3期23卷 560-562页

作者： Jennifer Anne Campbell Andrew James irvine Andrew Derek Hopper Department of Gastroenterology Royal Hallamshire HospitalSheffield S10 2JFUnited Kingdom

There is compelling evidence to support the quality,cost effectiveness and safety profile of non-anesthesiologist-administered propofol for endoscopic ultrasound (EUS). However in the United Kingdom, it is recommended that the administration and monitoring of propofol sedation for endoscopic procedures should be the responsibility of a dedicated and appropriately trained anaesthetist only. The majority of United Kingdom EUS procedures are performed with opiate and benzodiazepine sedation rather than anaesthetist led propofol lists due to anaesthetist resource availability. We sought to prospectively determine the tolerability and safety of EUS with benzodiazepine and opiate sedation in single United Kingdom centre. Two hundred consecutive patients undergoing either EUS or oesophago-gastroduodenoscopy (OGD) with conscious sedation were prospectively recruited with a 1:1 enrolment ratio. Patients completed questionnaires pre and post procedure detailing anticipated and actual pain experienced on a 1-10 visual analogue scale. Demographics, procedure duration, sedation doses and willingness to repeat the procedure were also recorded. EUS procedures lasted significantly longer than OGDs(15 min vs 6 min, P < 0.0001), however, there was no difference in anticipated pain scores between the groups(EUS 3.37/10 vs OGD 3.47/10, P = 0.46). Pain scores indicated EUS was better tolerated than OGD(1.16/10 vs 1.88/10, P = 0.03) although higher doses of sedation were used for EUS procedures. There were no complications identified in either group. We feel our study demonstrates that the tolerability of EUS with opiate and benzodiazepine sedation is acceptable.

关键词： Sedation Endoscopy Tolerability Propofol Endoscopic ultrasound

A Japanese version of the stressors in nursing students(SINS)scale

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International Journal of Nursing Sciences 2018年第2期5卷 181-185页

作者： Roger Watson Kumi Watanabe Ayako Yamashita Mieko Yamaguchi Caroline Bradbury-Jones Fiona irvine University of Hull HullHU67RXUK Kagawa University Kagawa Prefecture761-0793Japan Niimi College Niimi718-8585Japan Okayama Prefectural University OkayamaJapan University of Birmingham BirminghamB152TTUK

Objectives:To translate and study the factor structure of a Japanese version of the Stressors in Nursing Students ***:The Stressors in Nursing Students scale was translated into Japanese and administered to a large cohort(N=1298)of female Japanese nursing students across five universities and across all four years of the nursing *** data were analysed using exploratory factor ***:Exploratory factor analysis revealed four factors:‘Clinical’;‘Conflict and confidence’;‘Education’;and‘Free time’.The relationship between the total score on the Stressors in Nursing Students scale and the demographic aspects of the sample was weak but there was a significant increase in the perception of stressors between first and second year ***:There were similarities and differences between the perception of stressors by nursing students in Japan compared with,for example,the United Kingdom and China *** a fourfactor structure was found here,the distribution of items in the Stressors in Nursing Students scale differed from previous studies in the United Kingdom and China with the‘Free time’factor being unique to this *** is an issue for nursing students and is related to the specific stressors they encounter in the process of their work and *** can inform the development of strategies to reduce such stressors among nursing students in multiple,global contexts.

关键词： Nursing students Factor analysis Japan Stressors

Exsolved materials for CO_(2)reduction in high-temperature electrolysis cells

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Materials Reports(Energy) 2023年第2期3卷 62-81,I0003页

作者： Min Xu Ran Cao Han Qin Nuoxi Zhang Wenle Yan Liming Liu John T.S.irvine Di Chen The Future Laboratory Tsinghua UniversityBeijing100084China Academy of Arts&Design Tsinghua UniversityBeijing100084China Weiyang College Tsinghua UniversityBeijing100084China School of Materials Science and Engineering Tsinghua UniversityBeijing100084China School of Chemistry University of St AndrewsSt AndrewsFifeKY169STUK

Electrochemical reduction of CO_(2)into valuable fuels and chemicals has become a contemporary research area,where the heterogeneous catalyst plays a critical *** nanoparticles supported on oxides performing as active sites of electrochemical reactions have been the focus of intensive ***,we review the CO_(2)reduction with active materials prepared by *** fundamental of exsolution was summarized in terms of mechanism and models,materials,and driven *** advances in the exsolved materials used in hightemperature CO_(2)electrolysis were catalogued into tailored interfaces,synergistic effects on alloy particles,phase transition,reversibility and electrochemical switching.

关键词： CO_(2)reduction Exsolution Solid oxide electrolysis cells Catalysts

Sommerfeld enhancement for thermal relic dark matter

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Sommerfeld enhancement for thermal relic dark matter

Dissecting American Anxieties over the Rise of China from Historical and Cultural Perspectives

2010粒子物理宇宙学研讨会

作者： Hai-Bo Yu UC irvine

＜正＞～～

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Dissecting American Anxieties over the Rise of China from Hi...

NEURAL PROTECTION BY NATUROPATHIC COMPOUNDS-FROM RETINA TO BRAIN

北京论坛（2005）文明的和谐与共同繁荣——全球化视野中亚洲的机遇与发展

作者： Chen,Yong University of California,irvine

Introduction In the past two centuries,China remained a country of poverty,and despair and suffering. In the last 20 years or so,however,a new China was quietly born,without the bloodshed of a revolution or great men loudly and proudly announcing the beginning of a new *** changes that have taken place are reversing the trajectory of modem Chinese history and shifting the paradigm of out world.

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NEURAL PROTECTION BY NATUROPATHIC COMPOUNDS-FROM RETINA TO B...

Evaluation of Sensory Properties of Probiotic Yogurt Containing Food Products with Prebiotic Fibresin Mwanza, Tanzania

第十八届国际眼科研究大会

作者： Zhiqun Tan University of California irvine School of Medicine irvine CA 92697 USA.

＜正＞Neurodegeneratiou characterized pathologically with fragmentation of neuronal processes, accumulation of protein aggregates,and loss of neurons along with provocative inflammatory signs in the nervous system has been profoundly implicated in the pathogenesis of both global and peripheral neuropathies such as Alzheimer’s disease（AD）,

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Food and Nutrition Sciences 2011年第5期2卷 434-439页

作者： Stephanie L. irvine Sharareh Hekmat National Institute for Medical Research Division of Food and Nutritional Sciences Brescia University College The University of Western Ontario

Yogurt becomes a functional food upon incorporating probiotics-live microorganisms which when adequately administered confer health benefits. Prebiotics are fermentable fibres that nourish beneficial gastrointestinal microflora enhance the functionality of probiotics. This research aimed to improve the acceptability and functionality of probiotic yogurt produced in Mwanza, Tanzania by incorporating probiotic food ingredients. The probiotic culture Lactobacillus rhamnosus GR-1 and standard yogurt cultures Lactobacillus delbrueckii bulgaricus and Steptococcus thermophilus were used to manufacture yogurt, then locally available prebiotic food ingredients containing fructooligosaccha- ride/inulin were incorporated. A nine-point facial hedonic scale was used to evaluate five yogurt samples. A mean score between one and three indicated that the sample product was well accepted. Probiotic yogurt containing onions, garlic and sweet potato received a score of 1.6 ± 0.84 (p 0.90), and plantains, 5.3 ± 2.56 (p > 0.90) were not well accepted. Sweet, mildly flavored prebiotic ingredients were most successfully incorpo- rated into probiotic yogurt in Mwanza.

关键词： Probiotics Prebiotics Yogurt Functional Food

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太阳能发电面临的挑战与机遇(英文)

电网技术 2007年第20期31卷 82-89页

作者： Stuart James Curzon irvine Anne Stafford 威尔士班戈大学化学系

在所有可再生能源中,光伏太阳能只占一小部分,然而在早期采用它的国家中,如日本和德国,却对全球工业体系起到了促进作用,对未来能源需求产生了意义深远的影响。讨论了光伏模块的当前成本和计划中的成本以及为了拓宽光伏太阳能的应用,材... 详细信息

在所有可再生能源中,光伏太阳能只占一小部分,然而在早期采用它的国家中,如日本和德国,却对全球工业体系起到了促进作用,对未来能源需求产生了意义深远的影响。讨论了光伏模块的当前成本和计划中的成本以及为了拓宽光伏太阳能的应用,材料科学能够为降低此成本壁垒而作出贡献的途径。文章对当前统辖市场的相对成熟的单晶硅光伏电池和有可能降低光伏模块成本的薄膜光伏电池进行了比较,指出薄膜光伏电池的转换效率需要提高而且应该能够进行大规模生产。文中给出了当前碲化镉光伏电池材料研究的一些实例,并对它们应如何在将来进行改进提出了建议。

关键词：碲化镉单品硅光伏太阳能电池可再生能源太阳能薄膜太阳能电池

Sex differences in cognitive impairment in Alzheimer's disease

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World Journal of Psychiatry 2016年第1期6卷 54-65页

作者： Keith R Laws Karen irvine Tim M Gale School of Life and Medical Sciences University of Hertfordshire Hertfordshire Partnership University NHS Foundation Trust

Sex differences in neurocognitive abilities have been extensively explored both in the healthy population andin many disorders. Until recently, however, little work has examined such differences in people with Alzheimer's disease(AD). This is despite clear evidence that AD is more prevalent in women, and converging lines of evidence from brain imaging, post-mortem analyses, hormone therapy and genetics suggesting that AD affects men and women differently. We provide an overview of evidence attesting to the poorer cognitive profiles in women than in men at the same stage of AD. Indeed, men significantly outperform women in several cognitive domains, including: Language and semantic abilities, visuospatial abilities and episodic memory. These differences do not appear to be attributable to any differences in age, education, or dementia severity. Reasons posited for this female disadvantage include a reduction of estrogen in postmenopausal women, greater cognitive reserve in men, and the influence of the apolipoprotein E ε4 allele. Assessment of cognitive abilities contributes to the diagnosis of the condition and thus, it is crucial to identify the role of sex differences if potentially more accurate diagnoses and treatments are to emerge.

关键词： Dementia Gender Sex differences Cognition