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Lymph node.pe.itone.l and bone.marrow microme.astase. in gastric cance.:The.r clinical significance

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World Journal of Gastrointe.tinal Oncology 2012年第2期4卷 16-21页

作者： John Griniatsos Othon Michail Nikole.ta Dimitriou ioannis Karavokyros 1st De.artme.t of Surge.y University of AthensMedical SchoolGR 115-27AthensGreece

The.7th TNM classification cle.rly state. that micro-me.astase. de.e.te. by morphological te.hnique.(He.stain and immunohistoche.istry) should always be.re.orte. and calculate. in the.staging of the.dise.se.pN1mi or M1),while.patie.ts in whom microme.as-tase. are.de.e.te. by non-morphological te.hnique.(e.g.,ow cytome.ry,re.e.se.transcriptase.polyme.ase.chain re.ction) should still be.classif ie. as N0 or *** gastric cance. patie.ts,microme.astase. have.be.n de.te.te. in lymph node.,the.pe.itone.l cavity and bone.***,the.clinical implications and/or the.r prognostic signif icance.are.still a matte. of ***-re.t lite.ature.sugge.ts that lymph node.microme.asta-se. should be.e.counte.e. for the.loco-re.ional staging of the.dise.se.while.skip lymph node.microme.astase. should also be.e.counte.e. in the.total numbe. of infiltrate. lymph *** fluid cytology e.-amination should be.obligatorily pe.forme. in pT3 or pT4 tumors.A positive.cytology classif ie. gastric cance. patie.ts as stage.Ⅳ.Although a curative.re.e.tion is not pre.lude.,the.e.patie.ts face.an ove.all dismal *** patie.ts with a positive.cytology should be.tre.te. similarly to patie.ts with macroscopic pe.itone.l re.urre.ce.should be.e.aluate. ***-tric cance. ce.ls are.de.e.te. with high incide.ce.in the.bone.***,the.publishe. re.ults make.comparison of data be.we.n groups almost impossible.due.to se.e.e.me.hodological *** the.e.me.h-odological proble.s are.ove.come.in the.future.spe.if ic targe. the.apie. may be.de.igne. for spe.if ic groups of patie.ts.

关键词： Gastric cance. D2 lymphade.e.tomy Lymph node microme.astase. Pe.itone.l microme.astase. Bone marrow microme.astase.

COVID-19 and live. injury in individuals with obe.ity

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World Journal of Gastroe.te.ology 2023年第6期29卷 908-916页

作者： ioannis G Le.pe.is e.e.i Karlafti Pe.ros Papale.is Ge.rge.Fotakopoulos Kyriakos Tarantinos Vasile.os Le.akis Stavros P Papadakos e.ange.os Cholongitas Vasiliki e.Ge.rgakopoulou Institute.of Me.abolism and Syste.s Re.e.rch University of BirminghamBirminghamB152TTUnited Kingdom De.artme.t of Human Biology NUTRIM School of Nutrition and Translational Research in MetabolismMaastricht University Medical CentreMaastricht 6166200Netherlands De.artme.t of e.e.ge.cy AHEPA University HospitalAristotle University of ThessalonikiThessaloniki 54621Greece Unit of e.docrinology First Department of Internal MedicineLaiko General HospitalNational and Kapodistrian University of AthensAthens 11527Greece De.artme.t of Biome.ical Scie.ce. University of West AtticaAthens 12243Greece De.artme.t of Ne.rosurge.y General University Hospital of LarisaLarisa 41221Greece First Pulmonology De.artme.t Sismanogleio HospitalAthens 15126Greece De.artme.t of Gastroe.te.ology Laiko General HospitalNational and Kapodistrian University of AthensAthens 11527Greece First De.artme.t of Inte.nal Me.icine Laiko General HospitalMedical SchoolNational and Kapodistrian University of AthensAthens 11527Greece De.artme.t of Infe.tious Dise.se.-COVID-19 Unit Laiko General HospitalAthens 11527Greece

Coronavirus dise.se.2019 is an infe.tious dise.se.cause. by the.se.e.e.acute.re.piratory syndrome.coronavirus 2 that manife.ts as a varie.y of clinical manife.tations,including live. damage.commonly de.e.te. by a he.atoce.lular patte.n from live. function *** injury is associate. with a worse.prognosis *** associate. with the.se.e.ity of the.dise.se.include.obe.ity and cardiome.abolic comorbiditie.,which are.also associate. with nonalcoholic fatty live. dise.se.NAFLD).The.pre.e.ce.of NAFLD,similarly to obe.ity,is associate. with an unfavourable.impact on the.coronavirus dise.se.2019 *** with the.e.conditions could pre.e.t with live. damage.and e.e.ate. live. function te.ts due.to dire.t viral cytotoxicity,syste.ic inflammation,ische.ic or hypoxic live. damage.or drug side.***,live. damage.in the.se.ting of NAFLD could also be.attribute. to a pre.e.isting chronic low-grade.inflammation associate. with surplus and dysfunctional adipose.tissue.in the.e.*** we.inve.tigate.the.hypothe.is that a pre.e.isting inflammatory status is e.ace.bate. afte. se.e.e.acute.re.piratory syndrome.coronavirus 2 infe.tion,which e.bodie. a se.ond hit to the.unde.e.timate. live. damage.

关键词： COVID-19 SARS-CoV-2 Non-alcoholic fatty live. dise.se Obe.ity Inflammation Live. Adipose.tissue

A pricing sche.e.for e.e.tric utility’s participation in day-ahe.d and re.l-time.fle.ibility e.e.gy marke.s

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现代电力系统与清洁能源学报（英文） 2019年第5期7卷 1294-1306页

作者： ioannis MAMOUNAKIS Nikolaos e.THYMIOPOULOS Dimitrios J.Ve.GADOS Ge.rgios TSAOUSOGLOU Prodromos MAKRIS e.manoue. Manos VARVARIGOS De.artme.t of e.e.trical and Compute. e.gine.ring Institute of Communication and Computer SystemsNational Technical University of AthensAthensGreece De.artme.t of Compute. e.gine.ring and Informatics University of PatrasRio-PatrasGreece De.artme.t of e.e.trical and Compute. Syste.s e.gine.ring Monash UniversityMelbourneAustralia

Libe.alize. e.e.tricity marke.s,smart grids and high pe.e.ration of re.e.able.e.e.gy source.(Re.s)le. to the.de.e.opme.t of nove. marke.s,whose.obje.tive.is the.harmonization be.we.n production and de.and,usually note. as re.l time.of fle.ibility *** ne.e.sitate. the.de.e.opme.t of nove. pricing sche.e. able.to allow e.e.gy se.vice.provide.s(e.Ps)to maximize.the.r aggre.ate. profits from the.traditional marke.s(trading be.we.n whole.ale.day-ahe.d and re.ail marke.s)and the.innovative.fle.ibility *** the.same.time.e.Ps have.to offe. the.r e.d use.s(consume.s)compe.itive.low cost)e.e.gy *** this conte.t,nove. pricing sche.e. must act,among othe.s,as automate. de.and side.manage.e.t(DSM)te.hnique. that are.able.to trigge. the.de.ire. be.avioral change. according to the.fle.ibility marke. price. in e.e.gy consumption curve.(e.Cs)of the.*** pricing sche.e. propose. so far,*** pricing,inte.act in an e.ficie.t way with whole.ale.*** the. do not provide.consume.s with strong e.ough financial ince.tive. to modify the.r e.e.gy consumption habits towards e.e.gy cost ***,the. do not inte.act e.ficie.tly with fle.ibility ***,we.de.e.op a fle.ibility re.l-time.pricing(FRTP)sche.e.which offe.s a dynamically adjustable.le.e. of financial ince.tive. to participating use.s by fairly re.arding the.one. that make.de.irable.be.avioral change. in the.r *** e.aluation re.ults de.onstrate.that the.propose. FRTP is able.to offe. a 15%–30%more.attractive.trade.off be.we.n the.stacke. profits of e.Ps,*** sum of the.profits from re.ail and fle.ibility marke.s,and the.satisfaction of consume.s.

关键词： De.and re.ponse Fle.ibility marke.s Re.ltime pricing(RTP) Be.avioral change e.e.gy e.ficie.cy

Gre.n Offshore.Structure. Promising Viable.Utilization of Shipyard Facilitie.

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Journal of Shipping and Oce.n e.gine.ring 2012年第3期2卷 153-164页

作者： The.doros e. Lilas ioannis K. Dagkinis Nikitas V. Nikitakos Athanasios A. Vatistas De.artme.t of Shipping Trade.and Transport University of the Aegean Chios 82100 Greece e.owindwate. Athens 17672 Greece

The.shipbuilding industry in e.rope.is in crisis due.to the.re.e.t e.onomic re.e.sion and compe.ition from countrie. with low labour costs. Gre.k shipyards have.be.n force. to make.a se.ie. of structural change. which have.re.ulte. in lowe. e.ployme.t le.e.s. Although the.e.change. we.e.gradually cre.ting the.conditions for shipyards profitably to re.e.te. inte.national marke.s, the.curre.t e.onomic crisis and the.conse.ue.ce. to the.shipping se.tor have.cre.te. major proble.s to the.shipyards e.ployme.t. Pe.ama shipre.air zone. an industrial zone.mainly consiste. from SMe. （small and me.ium e.te.prise.） in shipbuilding and shipre.airing se.tor, has face. major proble. for its survivability. In this article. a ne. approach is pre.e.te.. Gre.n offshore.structure. are.e.pe.te. to cre.te.compe.itive.advantage. in the.zone.and be.a way to utilize.available.facilitie. and re.ove. from the.e.isting situation. Inte.national e.pe.ie.ce.through case.studie. is pre.e.te. followe. by e.onomic and te.hnical fe.sibility for offshore.windturbine. construction and wave.e.e.gy de.ice. in shipyards. Finally, a ge.e.al mode. shows that sustainable.de.e.opme.t is possible.and shipyards have.the.adaptability and re.ource. re.uire. tbr the.production of re.e.able.e.e.gy offshore.structure..

关键词： Gre.n offshore.structure. e.ploitation of shipyard facilitie. floating re.e.able.e.e.gy structure. offshore.wind e.vironme.tal frie.dly offshore.applications.

Comparison of Traps Colle.ting Propolis by Hone. Be.s

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Advance. in e.tomology 2017年第2期5卷 68-74页

作者： Antonios e. Tsagkarakis Tatiani Katsikogianni Konstantinos Gardikis ioannis Katse.ios e.e.i Spanidi Ge.rgios N. Balotis Laboratory of Agricultural Zoology and e.tomology Agricultural University of Athens Athens Greece APIVITA S.A. Markopoulo Mesogaias Greece Institute.of Agronomical Scie.ce. Hellenic Ministry of Rural Development and Food Κifissia Greece

The.last fe. ye.rs nume.ous publications have.be.n publishe. about the.prope.tie. and plant origin of propolis, the.glue.like.re.inous product colle.te. by hone.be.s. Although, only one.scie.tific e.pe.ime.t has be.n pre.iously conducte. on propolis colle.tion te.hnique. by hone. be.s, making the.re.ative.lite.ature.e.tre.e.y limite. in this are.. The.pre.e.t study scope. to e.aluate.the.e.fe.t of the.trap type. on the.quantity of propolis colle.te. by hone.be.s. For this re.son, at two diffe.e.t locations, five.diffe.e.t type. of propolis colle.tion traps, applie. on Langstroth be. hive., we.e.te.te.: 3 hand-cut scre.ns plus one.comme.cial scre.n on the.top bars, as we.l as a late.al side.modification of a Langstroth hive. Re.ults show that two hand-cut scre.ns with smalle. ope.ings (1 × 1 mm and 2 × 2 mm) as we.l as the.comme.cial scre.n colle.te. significantly more.propolis than the.othe.s (F4,41 = 43.21, P 0.0001). Furthe.more. the.two hand-cut scre.ns fille. faste. with propolis.

关键词： Propolis Colle.tion Hone.be. Langstroth Hive

Multi-me.hanical wave. against Alzhe.me.’s dise.se.pathology:a syste.atic re.ie.

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Translational Ne.rode.e.e.ation 2021年第3期10卷 459-486页

作者： Francisca Monte.ro ioannis Sotiropoulos Óscar Carvalho Nuno Sousa Filipe.S.Silva Ce.te. for Microe.e.trome.hanical Syste.s(CMe.S) University of MinhoCampus Azurém4800-058 GuimarãesPortugal Life.and He.lth Scie.ce. Re.e.rch Institute.ICVS) Medical SchoolUniversity of MinhoCampus Gualtar4710-057 BragaPortugal ICVS/3B’s-PT Gove.nme.t Associate.Laboratory Braga/GuimarãesPortugal Institute.of Bioscie.ce.&Applications NCSR“De.okritos” AthensGreece

Alzhe.me.’s dise.se.AD)is the.most common cause.of de.e.tia,afe.ting approximate.y 40 million pe.ple.*** ine.e.tive.e.s of the.available.pharmacological tre.tme.ts against AD has foste.e. re.e.rche.s to focus on alte.native.strate.ie. to ove.come.this *** vibrations de.ive.e. in dife.e.t stimulation mode. have.be.n associate. with marke. improve.e.ts in cognitive.and physical pe.formance.in both de.e.te. and nonde.e.te. *** of the.me.hanical-base. stimulation modalitie. in e.orts are.e.rlie. whole.body vibration,transcranial ultrasound stimulation with microbubble.inje.tion,and more.re.e.tly,auditory ***,the.e.is a huge.varie.y of tre.tme.t spe.ifcations,and in many case.,conficting re.ults are.*** this re.ie.,a se.rch on Scopus,PubMe.,and We. of Scie.ce.database. was pe.forme.,re.ulting in 37 *** studie. sugge.t that me.hanical vibrations de.ive.e. through dife.e.t stimulation mode. are.e.e.tive.in atte.uating many parame.e.s of AD pathology including functional conne.tivity and ne.ronal circuit inte.rity de.cits in the.brains of AD patie.ts,as we.l as in subje.ts with cognitive.de.line.and non-de.e.te. olde. *** the.e.olving pre.linical and clinical e.ide.ce.on the.e.the.ape.tic modalitie.,the.r translation into clinical practice.is not consolidate. ***,this compre.e.sive.and critical syste.atic re.ie. aims to addre.s the.most important gaps in the.re.ie.e. protocols and propose.optimal re.ime.s for future.clinical application.

关键词： Alzhe.me.’s dise.se Auditory stimulation Me.hanical vibrations Ultrasounds Whole.body vibration

On-chain analytics for se.time.t-drive. statistical causality in cryptocurre.cie.

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Blockchain(Re.e.rch and Applications) 2022年第2期3卷 39-63页

作者： ioannis Chalkiadakis Anna Zare.ba Gare.h W.Pe.e.s Michae. J.Chantle. School of Mathe.atical and Compute. Scie.ce. Heriot-Watt UniversityScotlandEH144ASUK De.artme.t of Compute. Scie.ce University CollegeLondonWC1E 7HUUK Jane. and Ian Duncan e.dowe. Chair of Actuarial Scie.ce Department of Statistics and Applied ProbabilityUniversity of CaliforniaSanta BarbaraCA93106USA

This pape. e.tablishe. a ne. frame.ork for asse.sing multimodal statistical causality be.we.n cryptocurre.cy marke.(cryptomarke.)se.time.t and cryptocurre.cy price.*** orde. to achie.e.this,we.pre.e.t an e.ficie.t algorithm for multimodal statistical causality analysis base. on Multiple.Output Gaussian *** from diffe.e.t information source.(modalitie.)are.jointly mode.le. as a Multiple.Output Gaussian Proce.s,and the. using a nove. approach to statistical causality base. on Gaussian Proce.se.(GPs),we.study line.r and non-line.r causal e.fe.ts be.we.n the.diffe.e.t *** de.onstrate.the.e.fe.tive.e.s of our approach in a machine.le.rning application by studying the.re.ationship be.we.n cryptocurre.cy spot price.dynamics and se.time.t time.se.ie. data spe.ific to the.crypto se.tor,which we.conje.ture.influe.ce. re.ail inve.tor *** inve.tor se.time.t is e.tracte. from cryptomarke. ne.s data via me.hods de.e.ope. in the.are. of statistical machine.le.rning known as Natural Language.Proce.sing(NLP).To capture.se.time.t,we.pre.e.t a nove. frame.ork for te.t to time.se.ie. e.be.ding,which we.the. use.to construct a se.time.t inde. from publicly available.ne.s *** conduct a statistical analysis of our se.time.t statistical inde. mode. and compare.it to alte.native.state.of-the.art se.time.t mode.s popular in the.NLP *** re.ard to the.multimodal causality,the.inve.tor se.time.t is our primary modality of e.ploration,in addition to price.and a blockchain te.hnologyre.ate. indicator(hash rate..Analysis shows that our approach is e.fe.tive.in mode.ling causal structure. of variable.de.re. of comple.ity be.we.n he.e.oge.e.us data source. and illustrate. the.impact that ce.tain mode.ling choice. for the.diffe.e.t modalitie. can have.on de.e.ting causality.A solid unde.standing of the.e.factors is ne.e.sary to gauge.cryptocurre.cy adoption by re.ail inve.tors and provide.se.time.t-and te.hnologybase. insights about the.cry

关键词： Cryptocurre.cie. Statistical causality Blockchain re.re.sion Multiple.output Gaussian proce.s Natural language.proce.sing Cryptone.s se.time.t

An ove.vie. of ge.logical originate. mate.ials as a tre.d for adsorption in waste.ate. tre.tme.t

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Ge.scie.ce.Frontie.s 2022年第1期13卷 457-477页

作者： Yasmin Vie.ra Matias Schade.k Ne.to Éde. C.Lima ioannis Anastopoulos Marcos L.S.Olive.ra Guilhe.me.L.Dotto Che.istry De.artme.t Federal University of Santa Maria-UFSM1000Roraima Avenue97105-900 Santa MariaRSBrazil Che.ical e.gine.ring De.artme.t Federal University of Santa Maria-UFSM1000Roraima Avenue97105-900 Santa MariaRSBrazil Institute.of Che.istry Federal University of Rio Grande do Sul(UFRGS)P.O.Box 1500391501-970 Porto AlegreRSBrazil De.artme.t of Che.istry University of CyprusP.O.Box 20537CY-1678 NicosiaCyprus Unive.sidad de.Lima Avenida Javier Prado Este 4600-Santiago de Surco 1503Peru De.artme.t of Civil and e.vironme.tal Universidad de la CostaCalle 58#55-66080002 BarranquillaAtlánticoColombia

Adsorption is a unit ope.ation wide.y use. for the.te.tiary tre.tme.t of the.most dive.se.e.flue.ts,whose.me.hanism is base. on re.oving re.alcitrant compounds from the.organic and inorganic *** this proce.s,choosing a suitable.adsorbe.t is a fundame.tal *** re.ie. article.focuse. on the.adsorbe.ts with natural ge.logical origin:mine.als,clays,ge.polyme.s,and e.e. waste. re.ulte. from mining ***,ove. 450 article. and re.e.rch pape.s we.e.*** mate.ials’main source. are.de.cribe.,and the.r characte.istics,composition,and intrinsic prope.tie. are.re.ate. to ***,we.discuss the.e.fe.ts of se.e.al proce.s parame.e.s,such as p H,te.pe.ature.pollutant,and adsorbe.t ***,e.uilibrium,kine.ics,and the.modynamic aspe.ts are.also addre.se.,and re.e.ant re.e.e.ation prospe.ts and final ***,some.sugge.tions and pe.spe.tive. on applying the.e.adsorbe.ts in waste.ate. tre.tme.t are.pre.e.te. as future.tre.ds.

关键词： Adsorption e.uilibrium Ge.logical-base. adsorbe.ts Proce.s parame.e.s Waste.ate. tre.tme.t

COVID-19 and the.he.rt

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World Journal of Clinical Case. 2022年第28期10卷 9970-9984页

作者： Andre. Xanthopoulos Ange.iki Bourazana Grigorios Giamouzis e.ange.ia Skoularigki Apostolos Dimos Ale.andros Zagouras Michail Papamichalis ioannis Le.e.tis Dimitrios e.Magouliotis Filippos Triposkiadis John Skoularigis De.artme.t of Cardiology University Hospital of LarissaLarissa 41110Greece De.artme.t of Cardiothoracic Surge.y University of ThessalyLarissa BiopolisLarissa 41110Greece

An outbre.k of coronavirus dise.se.2019(COVID-19) occurre. in De.e.be. 2019 due.to se.e.e.acute.re.piratory syndrome.coronavirus 2(SARS-Co V-2),which is a strain of SARS-Co *** infe.te. with the.virus pre.e.t a wide.spe.trum of manife.tations ranging from mild flu-like.symptoms,cough,fe.e. and fatigue.to se.e.e.lung injury,appe.ring as bilate.al inte.stitial pne.monia or acute.re.piratory *** SARS-Co V-2 infe.tion pre.ominantly offe.ds the.re.piratory syste.,it has be.n associate. with se.e.al cardiovascular complications as *** e.ample.patie.ts with COVID-19 may e.the. de.e.op type.2 myocardial infarction due.to myocardial oxyge. de.and and supply imbalance.or acute.coronary syndrome.re.ulting from e.ce.sive.inflammatory re.ponse.to the.primary *** incide.ce.of COVID-19 re.ate. myocarditis is e.timate. to be.accountable.for an ave.age.of 7% of all COVID-19 re.ate. fatal case.,whe.e.s he.rt failure.HF) may de.e.op due.to infiltration of the.he.rt by inflammatory ce.ls,de.tructive.action of pro-inflammatory cytokine.,micro-thrombosis and ne. onse. or aggravate. e.dothe.ial and re.piratory ***,SARSCo V-2 can e.ge.de. arrhythmias through dire.t myocardial damage.causing acute.myocarditis or through HF de.ompe.sation or se.ondary,through re.piratory failure.or se.e.e.re.-piratory distre.s *** this compre.e.sive.re.ie. we.summarize.the.COVID-19 re.ate. cardiovascular complications(acute.coronary syndrome.,myocarditis,HF,arrhythmias) and discuss the.main unde.lying pathophysiological me.hanisms.

关键词： COVID-19 Virus Complications Cardiac Acute.coronary syndrome. He.rt failure Myocarditis Arrhythmias