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Mate.ials Scie.ce. and Applications 2016年第1期7卷 73-82页

作者： Ge.rgios K. Triantafyllidis Dimitrios I. Zaglive.is Dionysios L. Kolioulis Christos S. Tsiompanis Titos N. Pasparakis Athanasios P. Gre.is Me.ina L. Sfantou ioannis e. giouvanakis De.artme.t of Che.ical e.gine.ring Aristotle University Thessaloniki Greece

Shie.de. Me.al Arc We.ding (SMAW) in Ductile.Irons (DI) is ofte. re.uire. by foundrie. for practical manufacturing re.sons. The.me.hanical prope.tie. of the.we.de. structure. are.strongly de.e.de.t on the.r HAZ’s width. A mode. base. on the.be.aviour of the.fe.ritic matrix of high-Si DIs in orde. to make.an approach in me.suring the.r HAZ’s width is de.e.ope. in this study. A se.ie. of the.mal tre.tme.ts on 3.35 and 3.75 wt% Si as-cast DIs and spot SMAWs is applie. on the.e.mate.ials. The.applie. SMAWs are.done.on non-pre.e.te. and pre.e.te. sample. (150℃ - 300℃). For we.ding we.modify the.ampe.age.(100 - 140A). The.micro-hardne.s Vicke.s change. in the.fe.rite.of the.as-cast sample. and inside.the.HAZ of the.we.de. one. can be.attribute. to the.e.iste.ce.of re.idual stre.se. (RS) in the.fe.ritic matrix and assist in e.timating the.HAZ’s width.

关键词： We.ds He.t Affe.te. Zone Re.idual Stre.se. Micro-Hardne.s Vicke.s He.t Affe.te. Zone.s Width

Manage.e.t of obstructe. colore.tal carcinoma in an e.e.ge.cy se.ting:An update

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World Journal of Gastrointe.tinal Oncology 2024年第3期16卷 598-613页

作者： e.stathios T Pavlidis ioannis N Galanis The.doros e.Pavlidis 2nd Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colore.tal carcinoma is common,particularly on the.le.t *** 20%of patie.ts,obstruction and ile.s may be.the.first clinical manife.tations of a carcinoma that has advance.(stage.II,III or e.e. IV).Diagnosis is base. on clinical pre.e.tation,plain abdominal radiogram,compute. tomography(CT),CT colonography and positron e.ission tomography/*** be.t manage.e.t strate.y in te.ms of short-te.m ope.ative.or inte.ve.tional and long-te.m oncological outcome. re.mains *** the.most common le.t-side. obstruction,the.first choice.should be.e.the. e.e.ge.cy surge.y or e.doscopic de.ompre.sion by se.f-e.pe.-dable.me.al ste.ts or *** ope.ative.plan should be.e.the. one.stage.or two-stage.***-stage.re.e.tion with on-table.bowe. de.ompre.sion and irrigation can be.accompanie. or not accompanie. by proximal de.unctioning stoma(colostomy or ile.stomy).Primary anastomosis is more.conve.ie.t but has incre.se. risks of anastomotic le.kage.and ***-stage.re.e.tion(Hart-mann’s proce.ure.is safe. and the.most wide.y use. de.pite.te.porally affe.ting quality of *** control surge.y in high-risk frail patie.ts is le.s fre.ue.tly pe.forme. since.it can be.succe.sfully substitute. with e.doscopic ste.ting or *** the.le.s common right-side. obstruction,one.stage.surgical re.e.tion is more.be.e.icial than e.doscopic *** role.of minimally invasive.surge.y(laparoscopic or robotic)is a subje.t of *** laparoscopic-assiste. manage.e.t is advantage.us to some.e.te.t but re.uire. much e.pe.tise.due.to inhe.e.t difficultie. in disse.ting the.diste.de. colon and the.risk of rup-ture.and subse.ue.t se.tic *** de.ompre.sing ste.t as a bridge.to e.e.tive.surge.y more.substantially de.re.se. the.risks of morbidity and mortality than e.e.ge.cy surge.y for de.ompre.sion and has e.uivale.t me.ium-te.m ove.all survival and dise.se.fre. survival *** combination with ne.adjuvant che.othe.apy or radiation may have.a p

关键词： Acute.abdome. Obstructive.ile.s Colore.tal carcinoma e.e.ge.cy surge.y Cole.tomy Intraluminal me.al ste.ts

Ne. tre.ds in diagnosis and manage.e.t of gallbladde. carcinoma

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World Journal of Gastrointe.tinal Oncology 2024年第1期16卷 13-29页

作者： e.stathios T Pavlidis ioannis N Galanis The.doros e.Pavlidis ^(nd)Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde.(GB)carcinoma,although re.ative.y rare.is the.most common biliary tre. cholangiocarcinoma with aggre.sive.e.s and poor *** is close.y associate. with chole.ithiasis and long-standing large.>3 cm)gallstone. in up to 90%of *** othe. main pre.isposing factors for GB carcinoma include.mole.ular factors such as mutate. ge.e.,GB wall calcification(porce.ain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made.by ultrasound,compute. tomography(CT),and,more.pre.ise.y,magne.ic re.onance.imaging(MRI).Pre.pe.ative.staging is of gre.t importance.in de.isionmaking re.arding the.ape.tic *** staging is base. on MRI findings,the.le.ding te.hnique.for live. me.astasis imaging,e.hance. thre.-phase.CT angiography,or magne.ic re.onance.angiography for major ve.se. *** is also ne.e.sary to use.positron e.ission tomography(Pe.)-CT or ^(18)F-FDG Pe.-MRI to more.accurate.y de.e.t me.astase. and any othe. occult de.osits with active.me.abolic *** laparoscopy may de.e.t disse.ination not othe.wise.found in 20%-28.6%of *** tre.tme.t is ne.de.,including surgical re.e.tion,targe.e. the.apy by biological age.ts according to mole.ular te.ting ge.e.mapping,che.othe.apy,radiation the.apy,and *** is of gre.t importance.to unde.stand the.update. guide.ine. and curre.t tre.tme.t *** e.te.t of surgical inte.ve.tion de.e.ds on the.dise.se.stage.ranging from simple.chole.yste.tomy(T1a)to e.te.de. re.e.tions and including e.te.de. chole.yste.tomy(T1b),with wide.lymph node.re.e.tion in e.e.y case.or IV-V se.me.te.tomy(T2),he.atic trise.me.te.tomy or major he.ate.tomy accompanie. by he.aticoje.unostomy Roux-Y,and adjace.t organ re.e.tion if ne.e.sary(T3).Laparoscopic or robotic surge.y shows fe.e. postope.ative.complications and e.uivale.t oncological outcome. whe. compare. to ope. surge.y,but much atte.tion must be.paid to avoiding *** addition to surge.y,nove. targe

关键词： Biliary tract ne.plasms e.trahe.atic cholangiocarcinoma Gallbladde. carcinoma Gallbladde. dise.se. Biliary tre. dise.se. Gastrointe.tinal malignancie.

Curre.t conside.ations on intraductal papillary ne.plasms of the.bile.duct and pancre.tic duct

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World Journal of Gastroe.te.ology 2024年第10期30卷 1461-1465页

作者： e.stathios T Pavlidis ioannis N Galanis The.doros e.Pavlidis 2^(nd) Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Pancre.tobiliary intraductal papillary ne.plasms(IPNs)re.re.e.t pre.ursors of pancre.tic cance. or bile.duct cholangiocarcinoma that can be.de.e.te. and *** advance. in diagnostic me.hods,ide.tifying the.e.pre.alignant le.ions is still challe.ging for tre.tme.t *** imaging,biomarke.s and mole.ular te.ts for ge.omic alte.ations can be.use. for diagnosis and *** inte.ve.tion in combination with ne. che.othe.ape.tic age.ts is conside.e. the.optimal tre.tme.t for malignant *** balance.be.we.n the.risk of malignancy and any risk of re.e.tion guide. manage.e.t policy;the.e.ore.tre.tme.t should be.individualize. base. on a me.iculous pre.pe.ative.asse.sme.t of high-risk *** of the.bile.duct is more.aggre.sive.thus,e.rly diagnosis and surge.y are.*** conse.vative.manage.e.t of low-risk pancre.tic branch-duct le.ions is safe.and e.fe.tive.

关键词： Biliary tre. dise.se. Pancre.tic cystic ne.plasms Biliary tract ne.plasms e.trahe.atic cholangiocarcinoma Pancre.tic ade.ocarcinoma

Curre.t conside.ations for the.surgical manage.e.t of gallbladde. ade.omas

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World Journal of Gastrointe.tinal Surge.y 2024年第6期16卷 1507-1512页

作者： e.stathios T Pavlidis ioannis N Galanis The.doros e.Pavlidis The.Se.ond De.artme.t of Propae.e.tic Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde. ade.omas are.rare.le.ions(0.5%)associate. with pote.tial malignant transformation,particularly with gallbladde. ade.omas that are.1 cm in *** de.e.tion and manage.e.t are.crucial for pre.e.ting le.hal carcinoma *** polyps can ofte. be.distinguishe. from the.more.ofte. nonne.-plastic chole.te.ol pse.dopolyps(5%-10%),which are.*** is the.first-line.tool for initial diagnosis and follow-up whe. *** que.tion is whe.he. chole.yste.tomy is always ne.e.sary for all *** manage.me.t of gallbladde. ade.omas is de.e.mine. according to the.size.of the.tumor,the.growth rate.of the.tumor,the.patie.t’s symptoms and whe.he. risk factors for malignancy are.***≥1 cm in size.an age.50 ye.rs and a familial history of gallbladde. carcinoma are.indications for imme.iate.laparoscopic ***,ultrasound follow-up is *** ade.omas 6-9 mm in size.the.abse.ce.of≥2 mm growth at 6 months,one.ye.r,and two ye.rs,as we.l as an ade.oma size.e.isting risk factors indicate. that no furthe. surve.llance.is ***,it would be.pre.e.able.to individualize.the.manage.e.t in doubtful *** inte.ve.tional modalitie. for pre.e.ving the.gallbladde. ne.d furthe. e.aluation,e.pe.ially to de.e.mine.the.long-te.m outcome..

关键词： Biliary dise.se. True.ne.plastic polyps Gallbladde. ade.omas Be.ign bi-liary tumors Gallbladde. polyps e.trahe.atic biliary ne.plasms

Slope.stability of re.laime. coal mine. through a ne. wate. filling inde.

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Journal of Rock Me.hanics and Ge.te.hnical e.gine.ring 2024年第3期16卷 828-839页

作者： Antonios Mikroutsikos Ale.andros I.The.charis Nikolaos C.Koukouzas ioannis e.Ze.golis Che.ical Proce.s&e.e.gy Re.ource. Institute Centre for Research&Technology HellasAthensGreece School of Mining and Me.allurgical e.gine.ring National Technical University of AthensAthensGreece

A common re.lamation practice.for close. coal surface.mine. is filling the. with wate. to form pit *** cre.tion and sustainability of the.e.lake. are.significantly affe.te. by the.stability of the.corre.ponding *** pre.e.t study provide. a ge.e.al frame.ork for analyzing the.wate. filling’s e.fe.t on slope.stability base. on a ne. wate. filling inde.,which can indire.tly conside. the.factors affe.ting the.proce.s and e.ficie.tly quantify the.filling spe.d’s *** assumptions of the.propose. approach are.thoroughly discusse.,and the.range.of the.wate. filling inde. is ***,the.safe.y factor is calculate. using the.finite.e.e.e.t me.hod with the.she.r stre.gth re.uction te.hnique.during the.filling proce.s for various conditions(soil prope.tie.,slope.ge.me.ry,hydraulic conditions,and wate. filling spe.d).Re.ults are.pre.e.te. as normalize. stability charts for practical *** the.wate. filling,the.stability gradually de.re.se. until the.re.e.voir re.che. a critical le.e. of 10%e.0%of the.total he.ght;it the. incre.se. to e.e. more.stable.conditions than the.initial ***,the.pre.e.t analysis allows for the.pre.iminary stability e.aluation of a coal mine.during the.formation of a pit lake.and the.appropriate.quantification of the.wate. filling’s e.fe.t.

关键词： Post-coal e.a Ope.-pit flooding Stability charts Critical le.e.

Critical conside.ations for the.manage.e.t of acute.abdome. in transplant patie.ts

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World Journal of Transplantation 2024年第2期14卷 8-12页

作者： e.stathios T Pavlidis Ge.rgios Katsanos Athanasios Kofinas Ge.rgios Tsoulfas ioannis N Galanis The.doros e.Pavlidis The.2^(nd)De.artme.t of Propae.e.tic Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece De.artme.t of Transplantation Surge.y Center for Research and Innovation in Solid Organ TransplantationAristotle University of ThessalonikiSchool of MedicineThessaloniki 54642Greece

The.numbe. of solid organ transplantations pe.forme. annually is incre.sing and are.incre.sing in the.following orde.:Kidne.,live.,he.rt,lung,pancre.s,small bowe.,and ute.ine.***,the.outcome. of transplants are.impro-ving(organ survival>90%afte. the.1st ye.r).The.e.ore.the.e.is a high probability that a ge.e.al surge.n will be.face. with the.manage.e.t of a transplant patie.t with acute.*** proble.s in immunocompromise. patie.ts may not only include.graft-re.ate. proble.s but also nongraft-re.ate. *** pe.iope.ative.re.ulation of immunosuppre.sion,the.tre.tme.t of accompanying proble.s of immunosuppre.sion,the.administration of cortisol and,above.all,the.re.lization of a rapidly de.e.iorating situation and the.accurate.e.aluation and inte.pre.ation of clinical manife.tations are.particularly important in the.e.*** pe.iope.ative.asse.sme.t and pre.aration include. e.aluation of the.patie.t’s cardiovascular syste. and de.e.mining if the.patie.t has hype.te.sion or suppre.sion of the.hypothalamic-pituitary-adre.al axis,or if the.patie.t has had any coagulation me.hanism abnormalitie. or thromboe.bolic *** in transplant patie.ts is associate. with the.use.of calci-ne.rin inhibitors,corticoste.oids,and antiprolife.ation *** time.,the.clinical picture.is atypical,re.ulting in de.ays in diagnosis and tre.tme.t and le.ding to incre.se. morbidity and *** compute. tomo-graphy is of utmost importance.for e.rly diagnosis and *** re.ipie.ts are.prone.to infe.tions,e.pe.ially spe.ific infe.tions cause. by cytome.alovirus and Clostridium difficile.and the. are.pre.ispose. to intraop-e.ative.or postope.ative.complications that re.uire.gre.t care.and *** is ne.e.sary to follow e.ide.ce.base. the.ape.tic ***,it is re.uire. that the.clinician choose.the.corre.t the.ape.tic plan for the.patie.t(conse.vative.e.e.ge.cy ope. surge.y or minimally invasive.s

关键词： Acute.abdome. Abdominal e.e.ge.cy surge.y Transplantation Immunocompromise. patie.ts Immuno-suppre.sion Posttransplantation surge.y

Assistive.te.hnique. and the.r adde. value.for tre.or classification in multiple.scle.osis

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Ne.ral Re.e.e.ation Re.e.rch 2024年第5期19卷 977-978页

作者： Nabin Koirala Abdulnasir Hosse. ioannis U.Isaias Je.s Volkmann Muthuraman Muthuraman Child Study Ce.te. School of MedicineYale UniversityNew HavenCTUSA De.artme.t of e.e.trical&Compute. e.gine.ring Sultan Qaboos UniversityAl-KhodMuscatOman Ne.ral e.gine.ring with Signal Analytics and Artificial Inte.lige.ce Department of NeurologyUniversity Hospital of WürzburgWürzburgGermany Ce.tro Parkinson e.Parkinsonism Azienda Socio Sanitaria Territoriale G.Pini-CTO20126 MilanItaly

Tre.or occurs in about half of multiple.scle.osis(MS)*** tre.or has a broad fre.ue.cy range.of 2.5-7 Hz,with a highe. pre.ale.ce.of postural tre.or(44%)compare. to inte.tional tre.or(6%)(Alusi e. al.,2001).Tre.or may affe.t the.uppe. and lowe. e.tre.itie.,he.d,and trunk,and may e.e. affe.t the.vocal cords in isolate. case. of palatal *** tre.or is classically attribute. to le.ions of the.brain ste.,ce.e.e.lum,or ce.e.e.lar pe.uncle.,and tre.or inte.sity has be.n shown to corre.ate.with the.numbe. of le.ions or the.r functional ***,re.e.t work has de.onstrate. that inflammatory damage.to the.ce.e.e.lo-thalamic and cortico-thalamic pathways might also play an important role.in causing tre.or,as it co-occurs with othe. signs and symptoms of MS such as dysarthria,dysme.ria,dysdiadochokine.ia,and dystonia(Alusi e. al.,2001).

关键词： tre.or scle.osis

Multifunctional HDPe.Cu biocidal nanocomposite. for Me. additive.manufacture. parts: Pe.spe.tive. for the.de.e.se.industry

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De.e.ce.Te.hnology（防务技术） 2024年第8期38卷 16-32页

作者： Ne.tarios Vidakis Nikolaos Michailidis Markos Pe.ousis Ne.tarios K.Nasikas Vassilios Saltas Vassilis Papadakis Nikolaos Mountakis Apostolos Argyros Mariza Spiridaki ioannis Valsamos De.artme.t of Me.hanical e.gine.ring Hellenic Mediterranean UniversityHeraklion 71410Greece Physical Me.allurgy Laboratory Mechanical Engineering DepartmentSchool of EngineeringAristotle University of ThessalonikiThessaloniki 54124Greece Ce.tre.for Re.e.rch&De.e.opme.t of Advance. Mate.ials(Ce.DAM) Center for Interdisciplinary Research and InnovationBalkan CentreThessaloniki 57001Greece Division of Mathe.atics and e.gine.ring Scie.ce. Department of Military SciencesHellenic Army AcademyVari GR16673AtticaGreece De.artme.t of e.e.tronic e.gine.ring Hellenic Mediterranean UniversityChania 73133Greece De.artme.t of Industrial De.ign and Production e.gine.ring University of West AtticaAthens 12244Greece Institute.of e.e.tronic Structure.and Lase. Foundation for Research and Technology-HellasHeraklion 70013Greece

In this study, we.inve.tigate. the.pe.formance.improve.e.t cause. by the.addition of coppe.(Cu)nanoparticle. to high-de.sity polye.hyle.e.HDPe. matrix mate.ial. Composite.mate.ials, with fille. pe.ce.tage. of 0.0, 2.0, 4.0, 6.0, 8.0, and 10.0 wt% we.e.synthe.ize. through the.mate.ial e.trusion(Me.)3D printing te.hnique. The.synthe.ize. nanocomposite.filame.ts we.e.utilize. for the.manufacturing of spe.ime.s suitable.for the.e.pe.ime.tal proce.ure.that followe.. He.ce. we.we.e.able.to syste.atically inve.tigate.the.r te.sile. fle.ural, impact, and microhardne.s prope.tie. through various me.hanical te.ts that we.e.conducte. according to the.corre.ponding standards. Broadband Die.e.tric Spe.troscopy was use. to inve.tigate.the.e.e.trical/die.e.tric prope.tie. of the.composite.. More.ve., by e.ploying me.ns of Raman spe.troscopy and the.mogravime.ric analysis(TGA) we.we.e.also able.to furthe. inve.tigate.the.r vibrational, structural, and the.mal prope.tie.. Concomitantly, me.ns of scanning e.e.tron microscopy(Se.), as we.l as atomic force.microscopy(AFM), we.e.use. for the.e.amination of the.morphological and structural characte.istics of the.synthe.ize. spe.ime.s, while.e.e.gy-dispe.sive.Xray spe.troscopy(e.S) was also pe.forme. in orde. to re.e.ve.a more.de.aile. picture.on the.structural characte.istics of the.various synthe.ize. composite.. The.corre.ponding nanomate.ials we.e.also asse.se. for the.r antibacte.ial prope.tie. re.arding Staphylococcus aure.s(S. aure.s) and e.che.ichia coli(e. coli) with the.assistance.of a me.hod name. scre.ning agar we.l diffusion. The.re.ults showe. that the.me.hanical prope.tie. of HDPe.be.e.ite. from the.utilization of Cu as a fille., as the. showe. a notable.improve.e.t. The.spe.ime. of HDPe.Cu 4.0 wt% was the.one.that pre.e.te. the.highe.t le.e.s of re.nforce.e.t in four out of the.se.e. te.te. me.hanical prope.tie.(for e.ample. it e.hibite. a 36.7%improve.e.t in the.fle.ural stre.gth, compare. to the.pure.matrix). At the.same

关键词： High-de.sity polye.hyle.e.HDPe. Coppe.(Cu) Mate.ial e.trusion(Me.) Me.hanical pe.formance e.e.trical prope.tie. Antibacte.ial De.e.se.and se.urity

Fe.al lung growth pre.icts the.risk for e.rly-life.re.piratory infe.tions and childhood asthma

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World Journal of Pe.iatrics 2024年第5期20卷 481-495页

作者： Dimitra e.Zazara Olympia Giannou Ste.e. Sche.anski Mirja Page.ke.pe. Anastasios D.Giannou Maike.Pincus ioannis Be.ios Ste.an Bonn Ania C.Muntau Kurt He.he. Anke.Die.e.t Pe.ra Clara Arck Division for e.pe.ime.tal Fe.o-Mate.nal Me.icine Department of Obstetrics and Fetal MedicineUniversity Medical Center Hamburg-Eppendorf(UKE)Martinistraße 5220251HamburgGermany Unive.sity Childre.’s Hospital UKEHamburgGermany Compute. e.gine.ring and Informatics De.artme.t Polytechnic SchoolUniversity of PatrasPatrasGreece Institute.of De.e.opme.tal Ne.rophysiology Center for Molecular Neurobiology Hamburg(ZMNH)UKEHamburgGermany De.artme.t of Obste.rics and Fe.al Me.icine UKEHamburgGermany De.artme.t of Ge.e.al Visceral and Thoracic SurgeryUKEHamburgGermany Se.tion of Mole.ular Immunology and Gastroe.te.ology Ⅰ.Department of MedicineUKEHamburgGermany Pe.iatrics and Pe.iatric Pne.mology Practice BerlinGermany Institute.of Me.ical Syste.s Biology ZMNHUKEHamburgGermany Hamburg Ce.te. for Translational Immunology UKEHamburgGermany

Background e.rly-life.re.piratory infe.tions and asthma are.major he.lth burde.s during *** pre.icting an incre.se. risk for e.rly-life.re.piratory dise.se. are.***,we.ide.tifie. the.pre.ictive.value.of ultrasound-monitore. fe.al lung growth for the.risk of e.rly-life.re.piratory infe.tions and *** Fe.al lung size.was se.ially asse.se. at standardize. time.points by transabdominal ultrasound in pre.nant wome. participating in a pre.nancy *** be.we.n fe.al lung growth and re.piratory infe.tions in infancy or e.rly-onse. asthma at five.ye.rs we.e.***-le.rning mode.s re.ying on e.tre.e.gradie.t boosting re.re.sor or classifie. algorithms we.e.de.e.ope. to pre.ict re.piratory infe.tion or asthma risk base. on fe.al lung *** mode. de.e.opme.t and validation,study participants we.e.randomly divide. into a training and a te.ting group,re.pe.tive.y,by the.e.ploye. *** e.hance. fe.al lung growth throughout pre.nancy pre.icte. a lowe. e.rly-life.re.piratory infe.tion *** se. was associate. with a highe. risk for re.piratory infe.tions in *** lung growth could also pre.ict the.risk of asthma at five.ye.rs of *** de.igne. thre. machine.le.rning mode.s to pre.ict the.risk and numbe. of infe.tions in infancy as we.l as the.risk of e.rly-onse. *** mode.s’R2 value. we.e.0.92,0.90 and 0.93,re.pe.tive.y,unde.scoring a high accuracy and agre.me.t be.we.n the.actual and pre.icte. *** variable. include. known risk factors and nove. pre.ictors,such as ultrasound-monitore. fe.al lung *** Sonographic monitoring of fe.al lung growth allows to pre.ict the.risk for e.rly-life.re.piratory infe.tions and asthma.

关键词： Asthma Child risk e.rly-life.re.piratory infe.tions Pre.atal lung de.e.opme.t Se.ual dimorphism