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bZIP17 regulates heat stress tolerance at reproductive stage in Arabidopsis

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aBIOTECH 2022年第1期3卷 1-11页

作者： Juan Gao Mei-ing wang Jing-Jing wang Hai-Ping Lu Jian-Xiang Liu State Key Laboratory of Plant Physiology and Biochemistry College of Life SciencesZhejiang UniversityHangzhou 310027China

High temperature elicits a well-conserved response called the unfol ded protein response(UPR)to bring protein homeostasis in the endoplasmic reticulum(ER).Two key UPR regulators bZIP28 and bZIP60 have been shown to be essential for maintaining fertility under heat stress conditions in Arabidopsis,however,the function of transcriptional activator bZIP17,a paralog of bZIP28,in heat stress response at reproductive stage is not *** we found that bzip17 mutant plants were sensitive to heat stress in terms of silique length and fertility comparing to that of wildtype(WT)Arabidopsis plants,and transcri ptomic analysis showed that 1380 genes were specifically up-regulated and 493 genes were specifically down-regulated by heat stress in the flowers of WT plants comparing to that in bzip17 mutant *** bZIP17-dependent up-regulated genes were enriched in responses to a biotic stresses such as water deprivation and salt *** chromatin immuno-preci pitation coupled with high-throughput sequencing(ChIP-Seq)uncovered 1645 genes that were direct targets of bZIP17 in MYC-bZIP17 expressing seedlings subjected to heat *** these 1645 genes,ERSE-II cis-element was enriched in the binding peaks of their promoters,and the up-regulation of 113 genes by heat stress in flowers was dependent on *** results revealed direct targets of bZIP17 in flowers during heat stress responses and demonstrated the important role of bZIP17 in maintai ning fertility upon heat stress in plants.

关键词： Arabidopsis bZIP17 Flower Fertility Heat Stress UPR

AN AHP MODEL FOR BRinging EXPERTS TO CONSENSUS ON MEDICAL PAYMENT STANDARDS

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Journal of Systems Science and Systems Engineering 2006年第2期15卷 247-255页

作者： Yuan-Huei HUANG Pei-Yeh CHANG Chih-Young HUNG Kuei-ing wang King-Jen CHANG Department of Surgery Hsin-Chu General HospitalTaiwanChina Department of Pediatric Surgery Chang Gung Children’s HospitalChang Gung UniversityCollege of MedicineTaiwanChina Institute of Management of Technology National Chiao Tung UniversityTaiwanChina Department of Information Management Ming Hsin University of Science and TechnologyTaiwanChina Department of Surgery National Taiwan University HospitalTaiwanChina

Many countries with health insurance systems conduct periodic payment standards reform. How to reach consensus in setting payment standards among different specialties with different agendas has become a critical issue. The purpose of this study is to construct an analytic hierarchy process （AHP） model to obtain judgments from experts about the importance of ＂factors related to establishing payment standards in the national health insurance program＂. Under this goal, the first tier contains four evaluation aspects, and the second tier contains sixteen evaluation criteria divided into four groups The AHP model was then used to collect and combine the opinions of experts through an empirical study. The results can be directly used to formulate standard values as the basis for establishing payment standards. The results of our study strongly support that an AHP model is effective in forming a consensus among surgical specialists.

关键词： National Health Insurance Analytic Hierarchy Process payment standards

Media: A Double-Edged Sword in the Disease Control. Content Analysis of News Report on SARS Event in Taiwan

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Health 2014年第14期6卷 1760-1766页

作者： Shiow-ing wang Chih-Liang Yaung Hung-En Liao Hung-Che Chiang Department of Healthcare Administration College of Health Science Asia University Taichung Taiwan National Environmental Health Research Center National Health Research Institutes Miaoli Taiwan

Objective: This study was conducted to explore what media exactly do when disease is emerging and furthermore, to infer the role and the responsibility that media should play. Method: A content analysis with 0.81 inter-rater reliability was adopted to categorize SARS-related events shown on the three major newspapers in 117 days, dated from March 13th (the date before the first probable case of SARS in Taiwan was identified) to July 7th (the date after Taiwan was removed from the list of SARS-affected countries by the bulletin of World Health Organization), 2003. Results: There were totally 8923 SARS events related news found in the observed newspapers during the study period. When the epidemic situation is more serious, the media will also lay out more coverage on reporting the related contents. In the reporting contents, the three most influential newspapers in Taiwan mainly emphasized the impact dimension (34.27%). Only 2.16% of the coverage was on the topic of health communication and prevention education. Overall, the opinions of general public are the primary sources of news (46.57%). Health authority was not the main and typical sources information of the press (9.42%). Conclusion: Media is a double-edged sword in the communicable disease control. We suggest that the health authority should take advantage of media to transmit message rapidly to convey related information to public.

关键词： Severe Acute Respiratory Syndrome (SARS) News Report Media Content Analysis

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纳米改性混凝土界面过渡区的多尺度表征

建筑材料学报 2017年第1期20卷 7-11页

作者：徐晶王彬彬赵思晨同济大学先进土木工程材料教育部重点实验室上海201804

从多尺度综合研究了纳米SiO_2对混凝土界面过渡区早期力学性能的影响.在宏观尺度上,主要测试了纳米改性混凝土的弹性模量及抗压、抗折强度,在微观尺度上,采用纳米压痕对其界面过渡区进行了压痕模量及其频数分布分析.结果表明:掺入纳米Si... 详细信息

从多尺度综合研究了纳米SiO_2对混凝土界面过渡区早期力学性能的影响.在宏观尺度上,主要测试了纳米改性混凝土的弹性模量及抗压、抗折强度,在微观尺度上,采用纳米压痕对其界面过渡区进行了压痕模量及其频数分布分析.结果表明:掺入纳米SiO_2后,无论水泥石还是混凝土,其早期强度及弹性模量均有所提高,且混凝土强度的提高尤为明显;纳米改性混凝土界面区的孔隙和缺陷显著减少,且形成了更高密度的C-S-H凝胶相,使其压痕模量与水泥石的压痕模量接近.

关键词：界面过渡区纳米SiO2 纳米压痕弹性模量

从神经内科疾病诊治谈临床逻辑思维能力的培养

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医学与哲学（B） 2017年第4期38卷 80-82,F0003页

作者：汪敬业汪凯安徽医科大学第一附属医院神经内科安徽合肥230022

临床逻辑思维能力是指运用逻辑思维方法解决临床实际问题的能力。随着医学检查技术的日益进步,医学生对临床逻辑思维能力培养的重视程度逐渐下降。殊不知,逻辑思维能力的提高有助于理论知识的学习、临床经验的积累以及实际问题的解决,... 详细信息

临床逻辑思维能力是指运用逻辑思维方法解决临床实际问题的能力。随着医学检查技术的日益进步,医学生对临床逻辑思维能力培养的重视程度逐渐下降。殊不知,逻辑思维能力的提高有助于理论知识的学习、临床经验的积累以及实际问题的解决,从而达到举一反三、融会贯通、事半功倍的效果。本文结合自身的学习经验从神经内科疾病诊治的角度,进一步阐述临床逻辑思维能力的重要性以及临床学习过程中如何培养逻辑思维能力。

关键词：临床逻辑思维能力重要性培养神经内科疾病

Increased expression of cyclooxygenase-2 in first-degree relatives of gastric cancer patients

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World Journal of Gastroenterology 2005年第31期11卷 4918-4922页

作者： Jin-Ting Zhang ing-Wei wang, Zhen-Long Zhu Xiao-Hui Huo Jian-Kun Chu Dong-Sheng Cui Liang Qiao Jun Yu Department of Medicine the First Affiliated Hospital of Hebei Medical UniversityShijiazhuang 050017 Hebei Province China Westmead Millennium Institute University of Sydney at Westmead Hospital NSW 2145Sydney Australia

AIM: To study the expression of cyclooxygenase-2 (COX-2)in human gastric cancer tissues and their paired adjacent mucosa, as well as mucosa from gastric antrum and corpus of the first-degree relatives of the recruited cancer ***: The expression of COX-2 mRNA in 38 patients with gastric cancer and their 29 first-degree relatives and 18 healthy controls was assessed by the real time *** expression of COX-2 protein was determined by Western ***: A marked increase in COX-2 mRNA expression was found in 20 of 37 (54%) cancerous tissues compared to their respective paired normal mucosa (P＜0.001).Interestingly, increased COX-2 mRNA expression was also found in mucosa of the corpus (6/29) and antrum (13/29)of their first-degree relatives. Increased COX-2 mRNA expression was more frequently observed in the antrum biopsies from cancer patients than in the antrum biopsies from healthy controls (P＜0.05). In addition, 3 of 23 (13%)patients with atrophic mucosa and 6 of 35 (17%) patients with intestinal metaplasia showed increased COX-2 mRNA expression. Furthermore, COX-2 expression increased in H pylori-positive tissues, especially in antrum ***: Increased COX-2 expression is involved in gastric carcinogenesis, and may be necessary for maintenance of the malignant phenotype and contribute to Helicobacterpylori-associated malignant transformation.

关键词： Gastric cancer First-degree relatives COX-2 H pylori

Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： Song He Li Li Sai wang Shao-Jiang wang Center for Theoretical Physics and College of Physics Jilin University School of Physical Science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) School of Physical Sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

Rational modulation of fluorophosphate cathode by anionic groups to reduce the polarization behavior for fast-charging sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 509-521页

作者： Xinyuan wang Fan Zhang Xingyu Zhou Qian wang Changyu Liu Yangyang Liu Hui wang Xiaojie Liu Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry & Materials Science Northwest University

Na3V2（PO4）2O2F （VP） is recognized as a promising cathode material for sodium-ion batteries due to its stable structural framework and high specific *** functional theory （DFT） and finite element simulations show that incorporating SO42-into VP decreases its band gap,lowers the migration energy barrier,and ensures a uniform Na+concentration gradient and stress distribution during charge and discharge ***,the average Na+diffusion coefficient of Na3V2（PO4）1.95（SO4）0.05O2F（VPS-1） is roughly double that of VP,leading to enhanced rate capability (80 C,75.5 mAh g-1) and cycling stability (111.0 mAh g-1capacity after 1000 cycles at 10 C current density) for ***-1 exhibits outstanding fast-charging capabilities,achieving an 80%state of charge in just 8.1 *** assembled VPS-1//SbSn/NPC full cell demonstrated stable cycling over 200 cycles at a high 5 C current,maintaining an average coulombic efficiency of 95.35%.

关键词： Anionic group modulation Polarization behavior Fast-charging Sodium-ion battery Fluorophosphate Cathode

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie wang Wei wang Xuheng Chen Junfang Bao Qiuyue Hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model