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世界建筑导报 2004年第1期19卷 86-87页

作者： mark Cousins Robert maxwell katharina Borsi Vlttoria Di Palma Hilde Heynen Psul Hirst marina Lathouri Neil Leach 怡工作人员

历史与理论课的设置使学生们能够对当代建筑学的发展与矛盾有较为深刻的理解。据信这是通过历史及不同学说来了解建筑学的一个良好的方法。我们用这种方法从充满现代主义语汇的建筑工程开始，发现这种方法被再次以狭隘的方式表现出来，... 详细信息

历史与理论课的设置使学生们能够对当代建筑学的发展与矛盾有较为深刻的理解。据信这是通过历史及不同学说来了解建筑学的一个良好的方法。我们用这种方法从充满现代主义语汇的建筑工程开始，发现这种方法被再次以狭隘的方式表现出来，并据此研究那些具有特殊意义的现代主义建筑师。它概括了到今天为止建筑理论的发展历史。该课程考虑了理论上各种不同的观点，并将他们渗透到各个层面的分析当中。另外，由历史与理论专业提供的这门课，鼓励学生从资秩学院和研究生院的课程中选修其他课程，并充分利用校内在晚间举办的各种讲座和其他活动，扩大学生的知识领域。在第二学期结束的时候，学生要提交份15000字的论文。在进一步的完善之后，经过研究、写作、讨论会及个别辅导，论文大纲在第三学期提交给特邀的建筑师和评审团成员。第四学期由个人最终完成论文。

关键词：发展历史现代主义大学生建筑工程建筑理论知识领域建筑学建筑师理论课课程

High-density lipoprotein endocytosis in endothelial cells

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World Journal of Biological Chemistry 2013年第4期4卷 131-140页

作者： Stefanie Fruhwürth margit Pavelka Robert Bittman Werner J Kovacs katharina m Walter Clemens Rhrl Herbert Stangl Clemens R hrl Herbert StanglCenter for Pathobiochemistry and GeneticsInstitute of Medical ChemistryMedical University of Vienna Department of Cell Biology and Ultrastructure Research Center for Anatomy and Cell BiologyMedical University of Vienna Department of Chemistry and Biochemistry Queens College of The City University of New York Institute of molecular Health Sciences Swiss Federal Institute of Technology Zürich Center for Pathobiochemistry and Genetics Institute of Medical ChemistryMedical University of Vienna

AIm: To describe the way stations of high-density lipoprotein(HDL) uptake and its lipid exchange in endothelial cells in vitro and in vivo. mETHODS: A combination of fluorescence microscopy using novel fluorescent cholesterol surrogates and electron microscopy was used to analyze HDL endocytosis in great detail in primary human endothelial cells. Further, HDL uptake was quantified using radio-labeled HDL particles. To validate the in vitro findings mice were injected with fluorescently labeled HDL and particle uptake in the liver was analyzed using fluorescencemicroscopy. RESULTS: HDL uptake occurred via clathrin-coated pits, tubular endosomes and multivesicular bodies in human umbilical vein endothelial cells. During uptake and resecretion, HDL-derived cholesterol was exchanged at a faster rate than cholesteryl oleate, resembling the HDL particle pathway seen in hepatic cells. In addition, lysosomes were not involved in this process and thus HDL degradation was not detectable. In vivo, we found HDL mainly localized in mouse hepatic endothelial cells. HDL was not detected in parenchymal liver cells, indicating that lipid transfer from HDL to hepatocytes occurs primarily via scavenger receptor, class B, type Ⅰ mediated selective uptake without concomitant HDL endocytosis. CONCLUSION: HDL endocytosis occurs via clathrincoated pits, tubular endosomes and multivesicular bodies in human endothelial cells. mouse endothelial cells showed a similar HDL uptake pattern in vivo indicating that the endothelium is one major site of HDL endocytosis and transcytosis.

关键词： High-density lipoprotein Endocytosis Endothelium Human umbilical vein endothelial cells Human coronary artery endothelial cells Cholesterol

子宫内膜异位症的诊断和管理：NICE指南概要

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英国医学杂志中文版 2018年第3期21卷 161-164页

作者： Laura Kuznetsov katharina Dworzynski melanie Davies Caroline Overton 李卫华朱磊 National Guideline Alliance Royal College of Obstetricians and Gynaecologists London NW1 4RG UK University College London Hospitals London UK St michael's University Hospital Bristol UK 首都医科大学附属北京朝阳医院妇产科

子宫内膜异位症是最常见的妇科疾病之一。生育年龄（15～49岁）妇女的发病率约为10％。子宫内膜异位症是英国第二位最常见的妇科疾病，仅次于子宫肌瘤。子宫内膜异位症是激素依赖性疾病，与月经周期相关。确切的发病原因不清，但普遍认... 详细信息

子宫内膜异位症是最常见的妇科疾病之一。生育年龄（15～49岁）妇女的发病率约为10％。子宫内膜异位症是英国第二位最常见的妇科疾病，仅次于子宫肌瘤。子宫内膜异位症是激素依赖性疾病，与月经周期相关。确切的发病原因不清，但普遍认为与经血逆流，促使子宫内膜细胞生长并定植于盆腔有关。

关键词：内膜增生摘要管理诊断子宫

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苏黎世——从保守的银行总部到时尚创意之都

国际城市规划 2012年第3期27卷 30-35页

作者：卡萨瑞娜.海德玛蒂娜.考-施耐森玛雅周勇德国多特蒙德大学空间规划学院欧洲规划文化系瑞士苏黎世联邦科技学院北京国城建筑设计公司

1凤凰涅槃：苏黎世在浴火中重生在32年前的那个夏天,苏黎世经历了一场变革之火的砺炼。1980年5月30日晚,在一场鲍勃·马利（Bob marley）的演唱会结束后,苏黎世歌剧院门口聚集了数百名激进主义青年,他们抗议政府拨给苏黎世歌剧院的一笔... 详细信息

1凤凰涅槃：苏黎世在浴火中重生在32年前的那个夏天,苏黎世经历了一场变革之火的砺炼。1980年5月30日晚,在一场鲍勃·马利（Bob marley）的演唱会结束后,苏黎世歌剧院门口聚集了数百名激进主义青年,他们抗议政府拨给苏黎世歌剧院的一笔高达6100万瑞士法郎的专项津贴。示威活动一直持续到第二天,这些年轻人还要求政府出资筹建真正属于他们自己的艺术中心——一个具有包容性的艺术交流场所——不仅可以承载那些长久以来统治着歌剧院和音乐厅等大雅之堂的主流艺术形式，更重要的是，也要为那些不起眼的非主流文化提供生存空间。抗议者最终将矛头指向了一个残酷的现实，即在这座城市中，总会有数以百万计的投资划给“主流艺术”，而那些“非主流艺术”却罕有人问津。

关键词：苏黎世艺术形式创意时尚银行保守歌剧院交流场所

成人急性心力衰竭的诊断与治疗：NICE指南概要

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英国医学杂志中文版 2015年第1期18卷 45-48页

作者： katharina Dworzynski Emmert Roberts Andrew Ludman Jonathan mant 王亭忠马爱群 National Clinical Guideline Centre Royal College of Physicians of London London NW1 4LE UK Academic Clinical Fellow in Psychiatry Mandsley Hospital South London and the Maudsley Mental Health Trust London UK Consultant Cardiologist Royal Devon and Exeter NHS Foundation Trust Exeter UK Primary Care Unit Department of Public Health and Primary Care University of Cambridge Cambridge UK 西安交通大学医学院第一附属医院

这是BmJ推出的基于当前最佳证据的新指南系列概要之一，强调了临床应用尤其是存在争议或矛盾之处的重要推荐。

关键词：衰竭心脏管理急性成人诊断

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灵活的糖衣包裹系统

流程工业 2009年第20期 52-52页

作者： katharina muffler Innojet Herbert Hūlin公司

如果要对不同形状、厚度、大小的药片、药丸等包裹一层高质量的糖衣，就需要采用高效的糖衣涂覆技术。一台新型糖衣包裹设备能够高质量地完成上述药片的糖衣包裹任务，并且还能够缩短药品生产的时间。

关键词：糖衣包裹系统涂覆技术药品生产药片质量药丸

A NEW HPLC mETHOD FOR THE QUANTITATIVE ANALYSIS OF HARPAGIDE AND HARPAGOSIDE IN SCROPHULARIAE RADIX: mONOGRAPH PROPOSAL FOR THE GERmAN PHARmACOPOEIA

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World Journal of Traditional Chinese medicine 2016年第2期 84-84页

作者： katharina Schiller J?rg Heilmann Detlef manns Gerhard Franz Pharmceutical Biology Department University of Regensburg Federal Institute for Drugs and medical Devices (BfArm)

Introduction:The increasing interest in Traditional Chinese medicine and the lack of quality monographs in the German Pharmacopoeia is the basis for research about the characterization of the most important herbal dru... 详细信息

关键词： A NEW HPLC mETHOD FOR THE QUANTITATIVE ANALYSIS OF HARPAGIDE AND HARPAGOSIDE IN SCROPHULARIAE RADIX mONOGRAPH PROPOSAL FOR THE GERmAN PHARmACOPOEIA

Imaging-based diagnosis of acute renal allograft rejection

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World Journal of Transplantation 2016年第1期6卷 174-182页

作者： Gerold Th?lking katharina Schuette-Nuetgen Dominik Kentrup Helga Pawelski Stefan Reuter Department of medicine D Division of General Internal Medicine Nephrology and Rheumatology University Hospital of Münster

Kidney transplantation is the best available treatment for patients with end stage renal disease. Despite the introduction of effective immunosuppressant drugs, episodes of acute allograft rejection still endanger graft survival. Since efficient treatment of acute rejection is available, rapid diagnosis of this reversible graft injury is essential. For diagnosis of rejection, invasive core needle biopsy of the graft is the "gold-standard". However, biopsy carries the risk of significant graft injury and is not immediately feasible in patients taking anticoagulants. Therefore, a non-invasive tool assessing the whole organ for specific and fast detection of acute allograft rejection is desirable. We herein review current imaging-based state of the art approaches for non-invasive diagnostics of acute renal transplant rejection. We especially focus on new positron emission tomography-based as well as targeted ultrasoundbased methods.

关键词： Acute allograft rejection Imaging Positron emission tomography Ultrasound magnetic resonance imaging Single photon emission computed tomography Kidney transplantation Renal

The Digital Agricultural Knowledge and Information System(DAKIS):Employing digitalisation to encourage diversified and multifunctional agricultural systems

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Environmental Science and Ecotechnology 2023年第4期16卷 177-189页

作者： Ioanna mouratiadou Nahleen Lemke Cheng Chen Ariani Wartenberg Ralf Bloch marco Donat Thomas Gaiser Deepak Hanike Basavegowda katharina Helming Seyed Ali Hosseini Yekani marcos Krull Kai Lingemann Joseph macpherson marvin melzer Claas Nendel Annette Piorr mostafa Shaaban Peter Zander Cornelia Weltzien Sonoko Dorothea Bellingrath-Kimura Leibniz Centre for Agricultural Landscape Research(ZALF) Eberswalder Straße 8415374MünchebergGermany ISARA Laboratory of Rural Studies Research UnitLyon23 Rue Jean Baldassini69364Lyon Cedex 07France Faculty of Landscape management and Nature Conservation University for Sustainable Development(HNEE)Schickler Straße 516225EberswaldeGermany Institute of Crop Science and Resource Conservation University of Bonn53115BonnGermany Leibniz Institute for Agricultural Engineering and Bioeconomy(ATB) Max-Eyth-Allee 10014469PotsdamGermany German Research Center for Artificial Intelligence(DFKI) Trippstadter Strasse 12267663KaiserslauternGermany Institute of Biochemistry and Biology University of PotsdamAm Mühlenberg 314476Potsdam(Golm)Germany Global Change Research Institute The Czech Academy of ScienceBělidla 986/4a60300BrnoCzech Republic

multifunctional and diversified agriculture can address diverging pressures and demands by simultaneously enhancing productivity,biodiversity,and the provision of ecosystem *** use of digital technologies can support this by designing and managing resource-efficient and context-specific agricultural *** present the Digital Agricultural Knowledge and Information System(DAKIS)to demonstrate an approach that employs digital technologies to enable decision-making towards diversified and sustainable *** develop the DAKIS,we specified,together with stakeholders,requirements for a knowledge-based decision-support tool and reviewed the literature to identify limitations in the current generation of *** results of the review point towards recurring challenges regarding the consideration of ecosystem services and biodiversity,the capacity to foster communication and cooperation between farmers and other actors,and the ability to link multiple spatiotemporal scales and sustainability *** overcome these challenges,the DAKIS provides a digital platform to support farmers'decision-making on land use and management via an integrative spatiotemporally explicit approach that analyses a wide range of data from various *** approach integrates remote and in situ sensors,artificial intelligence,modelling,stakeholder-stated demand for biodiversity and ecosystem services,and participatory sustainability impact assessment to address the diverse drivers affecting agricultural land use and management design,including natural and agronomic factors,economic and policy considerations,and socio-cultural preferences and ***,the DAKIS embeds the consideration of ecosystem services,biodiversity,and sustainability into farmers'decision-making and enables learning and progress towards site-adapted small-scale multifunctional and diversified agriculture while simultaneously supporting farmers'objectives and societal demands.

关键词： Digital agriculture Ecosystem services Decision support system Farming practices Biodiversity modelling Small-scale management