检索结果-南通市图书馆

Decoding molecular mechanisms:brain aging and Alzheimer's disease

Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay Ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah Mohammed Albassam imdad kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological Sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.

关键词： Alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Jungck's Common Fixed Point Theorem and E.A Property

引用

Acta Mathematica Sinica,English Series 2008年第1期24卷 87-94页

作者： M.imdad Javid ALI Department of Mathematics Aligarh Muslim University

We prove that （E.A） property buys the required containment of range of one mapping into the range of other in common fixed point considerations up to a pair of mappings. While proving our results, we utilize the ide... 详细信息

关键词： E.A property weak compatible mappings coincidence points fixed points and implicit functions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Secure Dengue Epidemic Prediction System: Healthcare Perspective

引用

Computers, Materials & Continua 2022年第10期73卷 1723-1745页

作者： Abdulaziz Aldaej Tariq Ahamed Ahanger Mohammed Yousuf Uddin imdad Ullah College of Computer Engineering and Science Prince Sattam bin Abdulaziz University Al-Kharj11942Saudi Arabia

Viral diseases transmitted by mosquitoes are emerging public health problems across the *** is considered to be the most significant mosquito-oriented ***,the present study provides an effective architecture for Dengue Virus Infection *** proposed system involves a 4-level architecture for the prediction and prevention of dengue infection *** architectural levels including Dengue Information Acquisition level,Dengue Information Classification level,DengueMining and Extraction level,and Dengue-Prediction and Decision Modeling level enable an individual to periodically monitor his/her probabilistic dengue fever *** prediction process is carried out so that proactive measures are taken *** predictive purposes,probabilistic analysis in terms of Level of Dengue Fever(LoDF)was carried out using the Adaptive NeuroFuzzy Inference *** on the Self-Organized Mapping procedure,the presence of LoDF is *** simulations on datasets of 16 individuals cumulating to 32,255 instances were conducted to test the effectiveness of the presented *** comparison to other decision-modeling methods,significantly improved results in form of classification efficacy,a temporal delay,prediction effectiveness,reliability,and stability were reported for the presented model.

关键词： Internet of things smart air real-time healthcare adaptive neuro-fuzzy inference system

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Securing Consumer Internet of Things for Botnet Attacks: Deep Learning Approach

引用

Computers, Materials & Continua 2022年第11期73卷 3199-3217页

作者： Tariq Ahamed Ahanger Abdulaziz Aldaej Mohammed Atiquzzaman imdad Ullah Mohammed Yousuf Uddin College of Computer Engineering and Science Prince Sattam bin Abdulaziz University Al-Kharj11942Saudi Arabia School of Computer Science University of Oklahoma Norman73019-6151United States

DDoS attacks in the Internet of Things(IoT)technology have increased significantly due to its spread adoption in different industrial *** purpose of the current research is to propose a novel technique for detecting botnet attacks in user-oriented IoT ***,an attack identification technique inspired by Recurrent Neural networks and Bidirectional Long Short Term Memory(BLRNN)is presented using a unique Deep Learning(DL)*** text identification and translation of attack data segments into tokenized form,word embedding is *** performance analysis of the presented technique is performed in comparison to the state-of-the-art DL ***,Accuracy(98.4%),Specificity(98.7%),Sensitivity(99.0%),F-measure(99.0%)and Data loss(92.36%)of the presented BLRNN detection model are determined for identifying 4 attacks over Botnet(Mirai).The results show that,although adding cost to each epoch and increasing computation delay,the bidirectional strategy is more superior technique model over different data instances.

关键词： Internet of Things deep learning security DDoS attack botnet

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phenotypic variations of wheat cultivars from the North China Plain in response to cadmium stress and associated single nucleotide polymorphisms identified by a genome-wide association study

引用

Pedosphere 2022年第4期32卷 555-564页

作者： imdad Ullah ZAID Sajid Hanif MUHAMMAD Na ZHANG Xin ZHENG Likun WANG Xiaofang LI Centre for Agricultural Resources Research Institute of Genetics and Developmental BiologyChinese Academy of SciencesShijiazhuang 050021China University of Chinese Academy of Sciences Beijing 100049China

Understanding the genetic mechanisms for cadmium (Cd) uptake and translocation in common wheat (Triticum aestivum) is of significance in food Cd contamination control. In this study, a diverse panel of 132 wheat cultivars was collected from the North China Plain. The cultivars were evaluated in terms of their phenotypic variations in response to Cd stress and subjected to a genome-wide association study (GWAS) to identify single nucleotide polymorphisms (SNPs) associated with the phenotypic variations at the seedling stage. Significant phenotypic variations with high heritability were observed among the wheat cultivars exposed to 40 μmol L-1 Cd for the studied traits, including root length (RL), shoot length (SL), root and shoot dry biomasses (RDW and SDW, respectively), root and shoot Cd concentrations (RCD and SCD, respectively), and Cd translocation factor (TF). Mean RCD, SCD, and TF ranged from 1.0 to 33.8, 0.125 to 2.022, and 0.009 to 0.321 mg g-1, respectively. Cluster analysis showed that wheat cultivars with higher RL, SL, RDW, and SDW under Cd stress were able to accumulate more Cd in root, leading to a lower Cd TF. Mixed linear model-based association analysis detected 17 novel significant marker-trait associations (MTAs), four of which were significant at a genome-wide scale. Most of the significant MTAs controlled Cd TF and explained 17.17%–26.47% of the phenotypic variations. Some of the SNP loci were physically close to a reported Cd-related quantitative trait locus or gene on wheat chromosomes. Results of this study provided a list of wheat cultivars with the potential of low Cd accumulation and enriched our knowledge on the genetic basis of Cd uptake and translocation in wheat. Pyramiding breeding of superior alleles detected in this study may additionally reduce Cd accumulation of improved wheat cultivars with excellent agronomic traits.

关键词： cadmium uptake common wheat marker-trait association phenotypic variation quantitative trait locus translocation factor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ZrO2催化无溶剂条件下醇的液相氧化反应

引用

催化学报 2007年第5期28卷 413-416页

作者： Mohammad ILYAS Mohammad SADIQ imdad KHAN 白沙瓦大学国家卓越物理化学研究中心白沙瓦25120巴基斯坦

采用一种环境友好的方法,以分子氧为氧化剂,以ZrO2为催化剂,在无溶剂的条件下实现了醇的选择性氧化.苯甲醛、环己酮和辛醛等是相应醇的主要氧化产物.考察了不同反应条件（搅拌速度、反应时间和温度）、催化剂制备参数（焙烧温度和负载... 详细信息

采用一种环境友好的方法,以分子氧为氧化剂,以ZrO2为催化剂,在无溶剂的条件下实现了醇的选择性氧化.苯甲醛、环己酮和辛醛等是相应醇的主要氧化产物.考察了不同反应条件（搅拌速度、反应时间和温度）、催化剂制备参数（焙烧温度和负载量）及氧分压等的影响.结果发现,对于醇氧化生成相应羰基化合物,1 223 K焙烧的ZrO2比723 K焙烧的ZrO2显示出更高的催化活性.催化剂在反应混合物中不溶解,可以通过简单的过滤使其分离并重复使用.当搅拌速度大于900 r/min时,对醇的转化速率无明显的影响.

关键词：氧化锆无溶剂液相氧化醇

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

添加异辛醇对水与金属表面接触角的影响

引用

化工学报 2012年第S2期63卷 38-41页

作者：孙晗俞丽华 imdad Hussain 马国远北京工业大学环境与能源工程学院制冷与低温工程系北京100124

向溴化锂水溶液中添加微量异辛醇表面活性剂,能显著增强溴化锂吸收式制冷机的吸收作用,提高制冷能力。但添加了异辛醇后,吸收式制冷机中的降膜蒸发器的换热效果却不能保证得到强化,有时出现降膜蒸发器的换热效果变差的现象。为探究导致... 详细信息

向溴化锂水溶液中添加微量异辛醇表面活性剂,能显著增强溴化锂吸收式制冷机的吸收作用,提高制冷能力。但添加了异辛醇后,吸收式制冷机中的降膜蒸发器的换热效果却不能保证得到强化,有时出现降膜蒸发器的换热效果变差的现象。为探究导致换热变差的原因,本研究通过测量异辛醇水溶液和金属板表面的接触角,发现水中加入微量异辛醇后接触角普遍增大,湿润性变差,使降膜蒸发器的传热变差。通过测量并比较同浓度异辛醇水溶液在不同金属表面的接触角,得出40mg·L-1时异辛醇水溶液在镀锌钢板表面的湿润性最好,其次是不锈钢板,在紫铜表面的湿润性最差。异辛醇水溶液的浓度变化对每种金属板接触角没有明显影响。

关键词：异辛醇降膜蒸发器接触角表面活性剂吸收式制冷

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of culturing conditions on survival and growth of the isolated chicken ovarian primordial follicles and cortical pieces

Effect of culturing conditions on survival and growth of the...

引用

全国动物生理生化第七届全国代表大会暨第十三次学术交流会

作者： imdad H.Leghari 米玉玲张才乔浙江大学动物科学学院动物医学系 Department of Poultry Husbandary Sindh Agriculture University

Primordial follicles are the basic structural unit of the ovary and make the reserve pool of the follicles throughout the life span of the avian and the *** culture models has been successfully optimised for mimicking...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Influence of reproductive organs parameters on the egg quality in different hen breeders

Influence of reproductive organs parameters on the egg quali...

引用

全国动物生理生化第七届全国代表大会暨第十三次学术交流会

作者： imdad H.Leghari 李军曾卫东米玉玲张才乔浙江大学动物科学学院动物医学系 Department of Poultry Husbandary Sindh Agriculture University

Since last three decades poultry production is facing the trend of high egg production,but currently this trend is also consorted with the egg quality *** egg quality depends on the synthesis of the yolk from the liver and its transportation to the oocytes and then deposition of albumin and shell gland layers around *** the about facts it is clear that every individual organ and its parts have

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

维甲酸对鸡胚生殖细胞减数分裂调控作用的研究

引用

畜牧与兽医 2012年第S1期44卷 218-219页

作者：于敏莉俞萍 imdad H Leghari 米玉玲张才乔浙江大学动物科学学院动物医学系浙江杭州310058

减数分裂是生殖细胞特有的、分化形成配子的过程,且在雌雄两性的发生时间不同。在胚胎期,雌性卵巢内生殖细胞即开始进入减数分裂,但在胚胎期睾丸中,RA被CYP26B1降解,使生殖细胞停滞在有丝分裂G0/G1期。在本实验中,我们结合胚胎期卵巢的... 详细信息

减数分裂是生殖细胞特有的、分化形成配子的过程,且在雌雄两性的发生时间不同。在胚胎期,雌性卵巢内生殖细胞即开始进入减数分裂,但在胚胎期睾丸中,RA被CYP26B1降解,使生殖细胞停滞在有丝分裂G0/G1期。在本实验中,我们结合胚胎期卵巢的体外培养和RNA干扰等手段,探索RA对鸡胚胎期生殖细胞减数分裂中的调控作用及其机制。

关键词：细胞减数分裂鸡胚胚胎期免疫荧光体外培养两性的维甲酸 RNA 信号通路合成酶基因

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：