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Experimental characterization of Ti6AI4V T joints welded through linear friction welding technique： microstructure and NDE

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Advances in Manufacturing 2016年第4期4卷 305-313页

作者： Antonello Astarita Mario Coppola Sergio Esposito Mariacira Liberini Leandro Maio ilaria papa Fabio Scherillo Antonino Squillace Department of Chemical Materials and ProductionEngineering University of Naples "Federico II" PiazzaleTecchio 80 80125 Naples Italy Fox Bit srl viale Luraghi presso consorzio I1 Sole80038 Pomigliano d'Arco NA Italy Leonardo Company S.p.A.- Aircraft Division Engineering -AT&D Manufacturing and Assembly Research andDevelopment Viale dell'Aeronantica s/n80038 Pomigliano d'Arco NA Italy Department of Industrial Engineering - Aerospace Division University of Naples "Federico II" Via Claudio 21 NaplesItaly

Linear friction welding （LFW） is an innovative solid-state welding technique that allows to manufacture joints with high mechanical properties. This technology has various applications in the aerospace field; in particular it is used to weld massive structural components made of Ti6A14V. This paper deals with the experimental study of Ti6A14V T-joints welded through LFW, with particular focus on the effectiveness of ultrasonic control in detecting and distinguishing welding defects within the joints. Aiming to this scope, joints with different properties were manufactured and tested： some were free from defects but with different metallurgy, and some had different types of defects. The results obtained proved that the ultrasonic control was an effective method to detect and identify defects in linear friction welded titanium joints, moreover it was possible to get information regarding the microstructure and in particular the extension of the different metallurgical zones induced by the welding process.

关键词： Ti6A14V Ultrasonic control Linear frictionwelding (LFW) Microstructure Defects

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Role of dynamic perfusion magnetic resonance imaging in patients with local advanced rectal cancer

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World Journal of Gastroenterology 2020年第20期26卷 2657-2668页

作者： Davide Ippolito Silvia Girolama Drago Anna Pecorelli Cesare Maino Giulia Querques ilaria Mariani Cammillo Talei Franzesi Sandro Sironi Department of Diagnostic Radiology H.S.Gerardo MonzaSan Gerardo HospitalUniversity of Milano-BicoccaMonza 20900Italy Department of Diagnostic Radiology Papa Giovanni XXIII HospitalUniversity of Milano-BicoccaBergamo 20110Italy

BACKGROUND The management of rectal cancer patients is mainly based on the use of the magnetic resonance imaging(MRI)technique as a diagnostic tool for both staging and *** treatment,to date,the evaluation of complete response is based on the histopathology assessment by using different tumor regression grade(TRG)features(e.g.,Dworak or Mandard classifications).While from the radiological point of view,the main attention for the prediction of a complete response after chemotherapy treatment focuses on MRI and the potential role of diffusion-weighted images and perfusion imaging represented by dynamiccontrast enhanced *** main aim is to find a reliable tool to predict tumor response in comparison to histopathologic *** To investigate the value of dynamic contrast-enhanced perfusion-MRI parameters in the evaluation of the healthy rectal wall and tumor response to chemo-radiation therapy in patients with local advanced rectal cancer with histopathologic *** Twenty-eight patients with biopsy-proven rectal adenocarcinoma who underwent a dynamic contrast-enhanced MR study performed on a 1.5 T MRI system(Achieva,Philips),before(MR1)and after chemoradiation therapy(MR2),were enrolled in this *** protocol included T1 gadolinium enhanced THRIVE sequences acquired on axial planes.A dedicated workstation was used to generate color permeability *** of interest was manually drawn on tumor tissue and normal rectal wall,hence the following parameters were calculated and statistically analyzed:Relative arterial enhancement(RAE),relative venous enhancement(RVE),relative late enhancement(RLE),maximum enhancement(ME),time to peak and area under the curve(AUC).Perfusion parameters were related to pathologic TRG(Mandard’s criteria;TRG1=complete regression,TRG5=no regression).RESULTS Ten tumors(36%)showed complete or subtotal regression(TRG1-2)at histology and classified as responders;18 tumors(64%)were classified as non-responders(TR

关键词： Rectal neoplasm Chemotherapy Radiotherapy Tumor staging Treatment response Magnetic resonance imaging

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