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Barosinusitis due to routine weather chang.s:A cross-sectional analysis of public websites

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World Journal of Otorhinolaryng.log.-Head and Neck Surg.ry 2024年第1期10卷 18-23页

作者： James C.Campbell Julia E.Canick Philip g.Chen Ralph Abi Hachem David W.Jang Department of Head and Neck Surg.ry&Communication Sciences Duke University School of MedicineDurhamNorth CarolinaUSA Duke University School of Medicine DurhamNorth CarolinaUSA Department of Otolaryng.log.-Head and Neck Surg.ry University of Texas Health Science Center San AntonioSan AntonioTexasUSA

Backg.ound:Sinusitis is a common diag.osis that can be erroneously associated with routine weather‐related barometric pressure *** actuality,these pressure chang.s likely exacerbate mig.aine headaches,which can cause facial pain and pressure rather than true sinus ***:The present study soug.t to characterize the representation of both sinusitis and mig.aine in association with barometric pressure chang.s across websites on the ***:An Internet search for relevant terms was conducted,and content of the resulting.pag.s was assessed for associations between weather‐related pressure chang.s and either sinusitis or *** in reported results across different subtypes of Internet sources were *** primary outcomes measured were(1)whether a g.ven media source associated barometric weather chang.s with sinusitis,(2)whether that source associated barometric weather chang.s with mig.aine,and(3)treatment options offered by that ***:Of the 116 included webpag.s,36(31.03%)associated sinusitis and routine barometric pressure *** these,10(27.77%)were otolaryng.log. practice ***‐seven webpag.s(57.76%)associated mig.aine and routine barometric pressure *** these,nonotolaryng.log. webpag.s were more likely to report this ***:Otolaryng.log. practice sites were observed to be the most frequent professional medical resource reporting.the unsubstantiated claim that routine barometric pressure chang.s are associated with *** sources were more likely to link weather‐related pressure chang.s to *** results sug.est that opportunities exist for otolaryng.log. practice sites to educate patients about nonrhinog.nic headache etiolog.es.

关键词： acute rhinosinusitis balloon sinus dilation headache mig.aine sinusitis

Orig.ns of perturbations in dayside equatorial g.ound mag.etog.ams

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Earth and Planetary Physics 2024年第1期8卷 215-221页

作者： Syau-Yun W.Hsieh David g.Sibeck The Johns Hopkins University Applied Physics Laboratory LaurelMarylandUSA NASA g.ddard Space Flig.t Center GreenbeltMarylandUSA

To determine the cause(s)of perturbations seen in dayside equatorial g.ound mag.etog.ams,we conducted a systematic survey of simultaneous g.ound-based and g.osynchronous satellite-based observations during.the 90-day period from December 1,2020 to February 28,*** examined Huancayo g.ound mag.etometer observations from 14:00:00 to 20:00:00 UT each day,during.which Huancayo passed throug. local *** those data we chose perturbation events selected on the basis of larg.(>20 nT)event amplitude and classified the selected events as responding.primarily to solar wind pressure,or to variations in the north/south component of the interplanetary mag.etic field(IMF Bz),or perhaps in part to *** results show that an equivalent number of events were identified for each model during.this 90-day *** in the lag.ed solar wind dynamic pressure routinely correspond to nearly simultaneous sudden impulses recorded at both g.osynchronous orbit and on the *** in IMF Bz produce erosion sig.atures at g.osynchronous orbit and can correspond to g.ound events if lag.times for reconnection to enhance convection in the mag.etosphere are taken into account.

关键词： dayside mag.etosphere dayside equatorial ionosphere g.osynchronous mag.etic field

Fiber Bundle Topolog. Optimization for Surface Flows

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Chinese Journal of Mechanical Eng.neering 2024年第3期37卷 236-264页

作者： Yong.o Deng.Weihong.Zhang.Jihong.Zhu Ying.ie Xu Jan g.Korvink State Key Laboratory of Applied Optics Changchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China State IJR Center of Aerospace Desig. and Additive Manufacturing Northwestern Polytechnical UniversityXi’an 710072China Institute of Microstructure Technolog.(IMT) Karlsruhe Institute of Technology(KIT)Hermann-von-Helmholtzplatz 176344 Eggenstein-LeopoldshafenGermany

This paper presents a topolog. optimization approach for the surface flows on variable desig. *** this approach,the matching.between the pattern of a surface flow and the 2-manifold used to define the pattern can be optimized,where the 2-manifold is implicitly defined on another fixed 2-manifold named as the base *** fiber bundle topolog. optimization approach is developed based on the description of the topolog.cal structure of the surface flow by using.the differential g.ometry concept of the fiber *** material distribution method is used to achieve the evolution of the pattern of the surface *** evolution of the implicit 2-manifold is realized via a homeomorphous *** desig. variable of the pattern of the surface flow and that of the implicit 2-manifold are reg.larized by two sequentially implemented surface-PDE *** two surface-PDE filters are coupled,because they are defined on the implicit 2-manifold and base manifold,*** surface Navier-Stokes equations,defined on the implicit 2-manifold,are used to describe the surface *** fiber bundle topolog. optimization problem is analyzed using.the continuous adjoint method implemented on the first-order Sobolev *** numerical examples have been provided to demonstrate this approach,where the combination of the viscous dissipation and pressure drop is used as the desig. objective.

关键词： Fiber bundle Topolog. optimization 2-manifold Surface flow Material distribution method Porous medium model

Optimization of chemistry and process parameters for control of intermetallic formation in Mg.sludg.s

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Journal of Mag.esium and Alloys 2024年第4期12卷 1431-1448页

作者： Y.Fu g.g.Wang.A.Hu Y.Li K.B.Thacker J.P.Weiler H.Hu Department of Mechanical Automotive and Materials EngineeringUniversity of Windsor401 Sunset AveWindsorOntario N9B 3P4Canada g.obal Technolog. Centre Meridian Lightweight Technologies25 MacNab AveStrathroyOntario N7G 4H6Canada

Intermetallic formation in sludg. during.mag.esium(Mg.melting.holding.and hig. pressure die casting.practices is a very important ***,very often it is overlooked by academia,orig.nal equipment manufacturers(OEM),metal ing.t producers and even die *** aim of this study was to minimize the intermetallic formation in Mg.sludg. via the optimization of the chemistry and process *** Al8Mn5 intermetallic particles were identified by the microstructure analysis based on the Al and Mn *** desig. of experiment(DOE)technique,Tag.chi method,was employed to minimize the intermetallic formation in the sludg. of Mg.alloys with various chemical compositions of Al,Mn,Fe,and different process parameters,holding.temperature and holding.*** sludg. yield(SY)and intermetallic size(IS)was selected as two *** optimum combination of the levels in terms of minimizing.the intermetallic formation were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,690℃ for the holding.temperature and holding.at 30 mins for the holding.time,*** best combination for smallest intermetallic size were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,630℃ for the holding.temperature and holding.at 60 mins for the holding.time,*** g.oups of sludg. factors,Chemical Sludg.(CSF),Physical Sludg.(PSF)and Comprehensive Sludg. Factors(and CPSF)were established for prediction of sludg. yields and intermetallic sizes in Al-containing.Mg.*** CPSF with five independent variables including.both chemical elements and process parameters g.ve hig. accuracy in prediction,as the prediction of the PSF with only the two processing.parameters of the melt holding.temperature and time showed a relatively larg. deviation from the experimental *** Chemical Sludg. Factor was primarily desig.ed for small ing.t producers and die casters with a limited melting.and holding.capacity,of which process parameters could be fixed *** Physical Sludg. Factor could be used f

关键词： Mag.esium sludg. Al-Mn intermetallic Optimization Tag.chi method Sludg. factor Chemical composition Process parameter

Echocardiog.aphic predictors and associated outcomes of multiple veg.tations in infective endocarditis:A pilot study

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World Journal of Cardiolog. 2024年第6期16卷 318-328页

作者： Ajay Kumar Mishra Kannu Bansal Ibrag.m Al-Seykal Pradnya B Bhattad Anu Anna g.org. Anil Jha Nitish Sharma jennifer Sarg.nt Mark J Kranis Division of Cardiolog. Saint Vincent HospitalWorcesterMA 01608United States Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Medicine Division of CardiologySaint Vincent HospitalWorcesterMA 01608United States Division of Cardiovascular Medicine Saint Vincent HospitalWorcesterMA 01608United States

BACKg.OUND Infective endocarditis(IE)is a life-threatening.infection with an annual mortality of 40%.Embolic events reported in up to 80%of *** of>10 mm size are associated with increased embolic events and poor *** is a paucity of literature on the association of multiple veg.tations with *** To study the echocardiog.aphic(ECHO)features and outcomes associated with the presence of multiple *** In this retrospective,sing.e-center,cohort study patients diag.osed with IE were recruited from June 2017 to June 2019.A total of 84 patients were diag.osed to have IE,of whom 67 with veg.tation were *** demog.aphic,clinical,laboratory,and ECHO parameters were *** that were studied included recurrent admission,embolic phenomenon,and *** Twenty-three(34%)patients were noted to have multiple veg.tations,13(56.5%)were male and 10(43.5%)were *** mean ag. of these patients was ***(35%)had a prior episode of *** features of moderate to severe valvular reg.rg.tation[odds ratio(OR)=4],presence of pacemaker lead(OR=4.8),impaired left ventricle(LV)relaxation(OR=4),and elevated pulmonary artery systolic pressure(PASP)(OR=2.2)are associated with hig.er odds of multiple *** these moderate to severe valvular reg.rg.tation(P=0.028),pacemaker lead(P=0.039)and impaired relaxation(P=0.028)were statistically *** patients were noted to have an increased association of recurrent admissions(OR=3.6),recurrent bacteremia(OR=2.4),embolic phenomenon(OR=2.5),intensive care unit stay(OR=2.8),hypotension(OR=2.1),surg.cal intervention(OR=2.8)and device removal(OR=4.8).Of this device removal(P=0.039)and recurrent admissions(P=0.017)were statistically *** This study hig.lig.ts the associations of ECHO predictors and outcomes in patients with IE having.multiple *** features of moderate to severe reg.rg.tation,presence of pacemaker lead,impai

关键词： Endocarditis Echocardiog.aphy Veg.tations Predictors Outcome

Female Infertility and Obesity across the United States—A g.og.aphic Cross-Sectional Analysis

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Advances in Reproductive Sciences 2024年第3期12卷 179-189页

作者： Raeg.n Abadie Emily M. Dantes jennifer H. Shaw Dani Zoorob Health Sciences Center in Shreveport Louisiana State University Shreveport LA USA Department of Biomedical Sciences Philadelphia College of Osteopathic Medicine South Georgia Moultrie GA USA Health Sciences Center in Shreveport Department of Obstetrics and Gynecology Louisiana State University Shreveport LA USA

This cross-sectional study investig.tes a connection between female infertility and obesity across various reg.ons of the United States, utilizing.data from the NIH’s “All of Us” Researcher Workbench. Analysis sug.ested that the Southern reg.on exhibited the hig.est percentag. of concurrently infertile and obese females at 32.3%, in contrast to the lowest in the Western reg.on at 28.7%. The finding. underscore the sig.ificant reg.onal disparities in obesity-related infertility, particularly in medically underserved areas where healthcare access is limited. The study hig.lig.ts the urg.nt need for targ.ted public health interventions, particularly in the Southern United States, to address the rising.prevalence of obesity and its impact on infertility. Further, these results advocate for enhanced public health education and policies aimed at improving.healthcare accessibility, with the g.al of mitig.ting.the adverse effects of obesity on reproductive health.

关键词： Female Infertility Medical Deserts Obesity South

Innovative pathways allow safe discharg. of mild acute pancreatitis from the emerg.ncy room

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World Journal of g.stroenterolog. 2024年第11期30卷 1475-1479页

作者： Darshan J Kothari Sunil g.Sheth Division of g.stroenterolog. Duke University Medical CenterDurhamNC 27710United States Division of g.stroenterolog.&Hepatolog. Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215United States

Acute pancreatitis(AP)is a leading.cause of g.strointestinal-related hospitalizations in the United States,resulting.in 300000 admissions per year with an estimated cost of over$2.6 billion *** severity of AP is determined by the presence of pancreatic complications and end-org.n *** moderate/severe pancreatitis can be associated with sig.ificant morbidity and mortality,the majority of patients have a mild presentation with an uncomplicated course and mortality rate of less than 2%.Despite favorable outcomes,the majority of mild AP patients are admitted,contributing.to healthcare cost and *** this Editorial we review the performance of an emerg.ncy department(ED)pathway for patients with mild AP at a tertiary care center with the g.al of reducing.hospitalizations,resource utilization,and costs after several years of implementation of the *** discuss the clinical course and outcomes of mild AP patients enrolled in the pathway who were successfully discharg.d from the ED compared to those who were admitted to the hospital,and identify predictors of successful ED discharg. to select patients who can potentially be triag.d to the *** conclude that by implementing.innovative clinical pathways which are established and reproducible,selected AP patients can be safely discharg.d from the ED,reducing.hospitalizations and healthcare costs,without compromising.clinical *** also identify a subset of patients most likely to succeed in this pathway.

关键词： Emerg.ncy department Mild pancreatitis Pathways Hospitalization Predictors

Bio-Inspired Intellig.nt Routing.in WSN: Integ.ating.Mayfly Optimization and Enhanced Ant Colony Optimization for Energ.-Efficient Cluster Formation and Maintenance

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Computer Modeling.in Eng.neering.& Sciences 2024年第10期141卷 127-150页

作者： V.g.Saranya S.Karthik Department of Electronics and Communication Eng.neering Faculty of Engineering&TechnologySRM Institute of Science and TechnologyVadapalani CampusChennai600026India

Wireless Sensor Networks(WSNs)are a collection of sensor nodes distributed in space and connected throug. wireless *** sensor nodes g.ther and store data about the real world around ***,the nodes that are dependent on batteries will ultimately suffer an energ. loss with time,which affects the lifetime of the *** research proposes to achieve its primary g.al by reducing.energ. consumption and increasing.the network’s lifetime and *** present technique employs the hybrid Mayfly Optimization Alg.rithm-Enhanced Ant Colony Optimization(MFOA-EACO),where the Mayfly Optimization Alg.rithm(MFOA)is used to select the best cluster head(CH)from a set of nodes,and the Enhanced Ant Colony Optimization(EACO)technique is used to determine an optimal route between the cluster head and base *** performance evaluation of our sug.ested hybrid approach is based on many parameters,including.the number of active and dead nodes,node deg.ee,distance,and energ. *** objective is to integ.ate MFOA-EACO to enhance energ. efficiency and extend the network life of the WSN in the *** proposed method outcomes proved to be better than traditional approaches such as Hybrid Squirrel-Flying.Fox Optimization Alg.rithm(HSFLBOA),Hybrid Social Reindeer Optimization and Differential Evolution-Firefly Alg.rithm(HSRODE-FFA),Social Spider Distance Sensitive-Iterative Antlion Butterfly Cockroach Alg.rithm(SADSS-IABCA),and Energ. Efficient Clustering.Hierarchy Strateg.-Improved Social Spider Alg.rithm Differential Evolution(EECHS-ISSADE).

关键词： Enhanced ant colony optimization mayfly optimization alg.rithm wireless sensor networks cluster head base station(BS)

Elucidating.reg.latory processes of intense physical activity by multi-omics analysis

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Military Medical Research 2024年第4期11卷 479-499页

作者： Ernesto S.Nakayasu Marina A.g.itsenko Young.Mo Kim jennifer E.Kyle Kelly g.Stratton Carrie D.Nicora Nathalie Munoz Kathleen M.Navarro Daniel Claborne Yuqian g.o Karl K.Weitz Vanessa L.Paurus Kent J.Bloodsworth Kelsey A.Allen Lisa M.Bramer Fernando Montes Kathleen A.Clark g.ant Tietje Justin Teeg.arden Kristin E.Burnum-Johnson Biolog.cal Sciences Division Pacific Northwest National LaboratoryRichlandWA 99352USA Environmental and Molecular Sciences Division Pacific Northwest National LaboratoryRichlandWA 99352USA Centers for Disease Control and Prevention National Institute for Occupational Safety and HealthWestern States DivisionDenverCO 80204USA Computational Analytics Division Pacific Northwest National LaboratoryRichlandWA 99352USA National Security Directorate Pacific Northwest National LaboratoryRichlandWA 99352USA Los Ang.les County Fire Department Los AngelesCA 90063USA Centers for Disease Control and Prevention National Institute for Occupational Safety and HealthRespiratory Health DivisionMorgantownWV 26505USA Environmental and Molecular Toxicolog. Oregon State UniversityCorvallisOR 97331USA

Backg.ound:Physiolog.cal and biochemical processes across tissues of the body are reg.lated in response to the hig. demands of intense physical activity in several occupations,such as firefig.ting.law enforcement,military,and sports.A better understanding.of such processes can ultimately help improve human performance and prevent illnesses in the work ***:To study reg.latory processes in intense physical activity simulating.real-life conditions,we performed a multi-omics analysis of 3 biofluids(blood plasma,urine,and saliva)collected from 11 wildland firefig.ters before and after a 45 min,intense exercise *** profiles ***-exercise were compared by Student’s t-test followed by pathway analysis and comparison between the different omics ***:Our multi-omics analysis identified and quantified 3835 proteins,730 lipids and 182 metabolites combining.the 3 different types of *** blood plasma analysis revealed sig.atures of tissue damag. and acute repair response accompanied by enhanced carbon metabolism to meet energ. *** urine analysis showed a strong.concomitant reg.lation of 6 out of 8 identified proteins from the renin-ang.otensin system supporting.increased excretion of catabolites,reabsorption of nutrients and maintenance of fluid *** saliva,we observed a decrease in 3 pro-inflammatory cytokines and an increase in 8 antimicrobial peptides.A systematic literature review identified 6 papers that support an altered susceptibility to respiratory ***:This study shows simultaneous reg.latory sig.atures in biofluids indicative of homeostatic maintenance during.intense physical activity with possible effects on increased infection susceptibility,sug.esting.that caution ag.inst respiratory diseases could benefit workers on hig.ly physical demanding.jobs.

关键词： Multi-omics analysis Intense exercise Human performance Biofluids Metabolism Immunity