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Rational Design of Ruddlesden-Popper Perovskite Ferrites as Air Electrode for Highly Active and Durable Reversible Protonic Ceramic Cells

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Nano-Micro Letters 2024年第9期16卷 308-324页

作者： Na Yu idris Temitope Bello Xi Chen Tong Liu Zheng Li Yufei Song Meng Ni Department of Building and Real Estate Research Institute for Sustainable Urban Development(RISUD)and Research Institute for Smart Energy(RISE)The Hong Kong Polytechnic UniversityHung HomKowloonHong KongPeople’s Republic of China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057GuangdongPeople’s Republic of China Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongPeople’s Republic of China

Reversible protonic ceramic cells(RePCCs)hold promise for efficient energy storage,but their practicality is hindered by a lack of high-performance air electrode ***-Popper perovskite Sr_(3)Fe_(2)O_(7−δ)(SF)exhibits superior proton uptake and rapid ionic conduction,boosting ***,excessive proton uptake during RePCC operation degrades SF’s crystal structure,impacting *** study introduces a novel A/B-sites co-substitution strategy for modifying air electrodes,incorporating Sr-deficiency and Nb-substitution to create Sr_(2.8)Fe_(1.8)Nb_(0.2)O_(7−δ)(D-SFN).Nb stabilizes SF’s crystal,curbing excessive phase formation,and Sr-deficiency boosts oxygen vacancy concentration,optimizing oxygen *** D-SFN electrode demonstrates outstanding activity and durability,achieving a peak power density of 596 mW cm^(−2)in fuel cell mode and a current density of−1.19 A cm^(−2)in electrolysis mode at 1.3 V,650℃,with excellent cycling *** approach holds the potential for advancing robust and efficient air electrodes in RePCCs for renewable energy storage.

关键词： Reversible protonic ceramic cells Air electrode Ruddlesden-Popper perovskite Hydration Oxygen reduction reaction

Adaptable and Dynamic Access Control Decision-Enforcement Approach Based on Multilayer Hybrid Deep Learning Techniques in BYOD Environment

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Computers, Materials & Continua 2024年第9期80卷 4663-4686页

作者： Aljuaid Turkea Ayedh M Ainuddin Wahid Abdul Wahab Mohd Yamani Idna idris Faculty of Computer Science and Information Technology Universiti MalayaKuala Lumpur50603Malaysia Faculty of Computer Science and Information Technology Shaqra UniversityShaqra11961Saudi Arabia Center for Mobile Cloud Computing Faculty of Computer Science and Information TechnologyUniversiti MalayaKuala Lumpur50603Malaysia

Organizations are adopting the Bring Your Own Device(BYOD)concept to enhance productivity and reduce ***,this trend introduces security challenges,such as unauthorized *** access control systems,such as Attribute-Based Access Control(ABAC)and Role-Based Access Control(RBAC),are limited in their ability to enforce access decisions due to the variability and dynamism of attributes related to users and *** paper proposes a method for enforcing access decisions that is adaptable and dynamic,based on multilayer hybrid deep learning techniques,particularly the Tabular Deep Neural Network Tabular DNN *** technique transforms all input attributes in an access request into a binary classification(allow or deny)using multiple layers,ensuring accurate and efficient access *** proposed solution was evaluated using the Kaggle Amazon access control policy dataset and demonstrated its effectiveness by achieving a 94%accuracy ***,the proposed solution enhances the implementation of access decisions based on a variety of resource and user attributes while ensuring privacy through indirect communication with the Policy Administration Point(PAP).This solution significantly improves the flexibility of access control systems,making themmore dynamic and adaptable to the evolving needs ofmodern ***,it offers a scalable approach to manage the complexities associated with the BYOD environment,providing a robust framework for secure and efficient access management.

关键词： BYOD security access control access control decision-enforcement deep learning neural network techniques TabularDNN multilayer dynamic adaptable flexibility bottlenecks performance policy conflict

Establishing delivery route-dependent safety and efficacy of living biodrug mesenchymal stem cells in heart failure patients

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World Journal of Cardiology 2024年第6期16卷 339-354页

作者： Muhammad Candragupta Jihwaprani idris Sula Mohamed Ahmed Charbat Khawaja Husnain Haider Basic Sciences SRCAl Bukayriyah 52736AlQaseemSaudi Arabia

BACKGROUND Mesenchymal stem cells(MSCs)as living biopharmaceuticals with unique properties,i.e.,stemness,viability,phenotypes,paracrine activity,etc.,need to be administered such that they reach the target site,maintaining these properties unchanged and are retained at the injury site to participate in the repair *** of delivery(RoD)remains one of the critical determinants of safety and *** study elucidates the safety and effectiveness of different RoDs of MSC treatment in heart failure(HF)based on phase II randomized clinical trials(RCTs).We hypothesize that the RoD modulates the safety and efficacy of MSCbased therapy and determines the outcome of the *** To investigate the effect of RoD of MSCs on safety and efficacy in HF *** RCTs were retrieved from six *** endpoints included mortality and serious adverse events(SAEs),while efficacy outcomes encompassed changes in left ventricular ejection fraction(LVEF),6-minute walk distance(6MWD),and pro-B-type natriuretic peptide(pro-BNP).Subgroup analyses on RoD were performed for all study *** Twelve RCTs were ***,MSC therapy demonstrated a significant decrease in mortality[relative risk(RR):0.55,95%confidence interval(95%CI):0.33-0.92,P=0.02]compared to control,while SAE outcomes showed no significant difference(RR:0.84,95%CI:0.66-1.05,P=0.11).RoD subgroup analysis revealed a significant difference in SAE among the transendocardial(TESI)injection subgroup(RR=0.71,95%CI:0.54-0.95,P=0.04).The pooled weighted mean difference(WMD)demonstrated an overall significant improvement of LVEF by 2.44%(WMD:2.44%,95%CI:0.80-4.29,P value≤0.001),with only intracoronary(IC)subgroup showing significant improvement(WMD:7.26%,95%CI:5.61-8.92,P≤0.001).Furthermore,the IC delivery route significantly improved 6MWD by 115 m(WMD=114.99 m,95%CI:91.48-138.50),*** biochemical efficacy outcomes,only the IC subgroup showed a significant reduction in pro-

关键词： Clinical trial Heart failure Mesenchymal stem cells Living biodrug Meta-analysis Stem cells Systematic review

Antimicrobial Activity of Some Commercial Toothpastes and Antibiotics on Two Oral Pathogenic Bacteria—An in-Vitro Study

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Journal of Biosciences and Medicines 2024年第3期12卷 168-181页

作者： Abubaker Elrotob idris Kabalci Department of Biomedical Engineering Engineering Faculty Karabuk University Karabuk Türkiye Department of Electric-Electronic Engineering Engineering and Natural Science Faculty U&scedilak University U&scedilak Türkiye Department of Electric-Electronic Engineering Engineering Faculty &Scedil&imathrnak University &Scedil&imathrnak Türkiye

Oral health problems such as periodontal diseases, dental caries, and endodontic infections have a significant negative impact on oral health and impose a substantial financial burden on the global population. The prevalence of these issues is increasing due to the buildup of bacterial plaque and the growing resistance of bacteria to antimicrobial treatments. The aims of this study to evaluate the anti-bacterial activity of four types of antibiotics (Amoxicillin, Augmentin, Azithromycin and Metronidazole) and four types of toothpastes (Sensodyne, ipana, denta and cariax Gingival Kin) on two oral pathogenic bacteria (Streptococcus mutans and Staphylococcus epidermidis). Bacterial samples of previously isolated Streptococcus mutans and Staphylococcusepidermidis were used as test organisms and the Kirby-Bauer disc diffusion method was employed to assess the antibacterial efficacy of various antibiotics and evaluate the impact of different toothpastes using a filter paper disc agar measurement technique. Each filter disc was saturated with toothpaste solution in a test tube for approximately 30 to 40 seconds, after which they were placed on Mueller-Hinton broth bacterial cultures in petri dishes. These Petri dishes were then incubated at 37°C for 24 hours, and the clear zone’s diameter (inhibition zone in mm) was subsequently measured and the results were recorded. The results demonstrated that Sensodyne toothpaste and Metronidazole antibiotic were ineffective against both types of bacteria, while Augmentin and Amoxicillin were effective by high diameter inhibition zones of growth against S. mutans and Azithromycine against S. epidermidis. Also Ipana, Denta, and Cariax Gingival Kin toothpastes exhibited a moderate effect against the two bacteria. This study suggests that certain antibiotics and toothpastes can effectively inhibit the growth of harmful oral bacteria, but not all of them are effective.

关键词： Antibacterial Effect Antibiotics Toothpastes Streptococcus mutans Staphylococcus epidermidis

Pseudorabies virus VHS protein abrogates interferon responses by blocking NF-κB and IRF3 nuclear translocation

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Virologica Sinica 2024年第4期39卷 587-599页

作者： Zhenfang Yan Jiayu Yue Yaxin Zhang Zhengyang Hou Dianyu Li Yanmei Yang Xiangrong Li Adi idris Huixia Li Shasha Li Jingying Xie Ruofei Feng Key Laboratory of Biotechnology and Bioengineering of State Ethnic Biomedical Research Center Northwest Minzu UniversityLanzhou730030China College of Life Science and Engineering Northwest Minzu UniversityLanzhou730030China Gansu Tech Innovation Center of Animal Cell Biomedical Research CenterNorthwest Minzu UniversityLanzhou730030China Engineering Research Center of Key Technology and Industrialization of Cell-based Vaccine Ministry of EducationBiomedical Research CenterNorthwest Minzu UniversityLanzhou730030China Centre for Immunology and Infection Control School of Biomedical SciencesQueensland University of TechnologyKelvin GroveQueensland4702Australia

Herpesviruses antagonize host antiviral responses through a myriad of molecular strategies culminating in the death of the host *** virus(PRV)is a significant veterinary pathogen in pigs,causing neurological sequalae that ultimately lead to the animal's *** is known to trigger apoptotic cell death during the late stages of *** virion host shutdown protein(VHS)encoded by UL41 plays a crucial role in the PRV infection *** this study,we demonstrate that UL41 inhibits PRV-induced activation of inflammatory cytokine and negatively regulates the cGAS-STING-mediated antiviral activity by targeting IRF3,thereby inhibiting the translocation and phosphorylation of ***,mutating the conserved amino acid sites(E192,D194,and D195)in the RNase domain of UL41 or knocking down UL41 inhibits the immune evasion of PRV,suggesting that UL41 may play a crucial role in PRV's evasion of the host immune response during *** results enhance our understanding of how PRV structural proteins assist the virus in evading the host immune response.

关键词： Pseudorabies virus(PRV) UL41 IRF3 Interferon cGAS-STING

Research on the Collaborative Governance of Social Responsibility in Online Audiovisual Enterprises

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Social Networking 2024年第1期13卷 1-13页

作者： Chuying Kang Muhammad Zaffwan idris Juan Liu Faculty of Art Sustainability & Creative Industry University Pendidikan Sultan Idris Tanjung Malim Malaysia Faculty of Journalism and Communication Henan University of Technology Zhengzhou China

This paper aims to analyze the present conditions of the social responsibility ecosystem in online audiovisual enterprises in the digital age. It focuses on the governance of social responsibility in these enterprises and conducts an in-depth analysis of the problems and influencing factors related to the social responsibility aberrations of online audiovisual enterprises. Drawing upon social responsibility theory and collaborative governance theory, this research constructs a social responsibility guidance and governance system guided by the public, supported by the voluntary fulfillment of responsibilities by online audiovisual enterprises, and based on the collaborative participation of diverse stakeholders. It explores and optimizes the implementation pathways of this system, providing theoretical support and practical guidance for promoting the sustainable development of online audiovisual enterprises. Furthermore, it aims to contribute to the creation of a harmonious Internet ecosystem.

关键词： Online Audiovisual Enterprises Social Responsibility Collaborative Governance

Sodium-Glucose Cotransporter-2 Inhibitors: Who, When & How? Guidance for Use from a Multidisciplinary Practical Approach

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International Journal of Clinical Medicine 2024年第9期15卷 413-435页

作者： Khalifa Abdullah Magdy ElSharkawy Emad R. Issak Ahmed Shawky ElSerafy Samah idris Ahmed Bendary Haytham Reda Badr May Shehata Ashraf Reda Internal Medicine Department Diabetes & Metabolism Unit Faculty of Medicine Alexandria University Alexandria Egypt Nephrology Department Faculty of Medicine Ain Shams University Cairo Egypt Internal Medicine Department Faculty of Medicine Ain Shams University Cairo Egypt Cardiology Department Faculty of Medicine Ain Shams University Cairo Egypt Internal Medicine and Nephrology Department Faculty of Medicine Alexandria University Alexandria Egypt Cardiology Department Faculty of Medicine Benha University Benha Egypt Internal Medicine Department Diabetes and Endocrinology Unit Faculty of Medicine Menoufia University Menoufia Egypt Product Manager Al-Esraa Pharma Cairo Egypt Cardiology Department Faculty of Medicine Menoufia University Menoufia Egypt

Sodium-glucose cotransporter-2 inhibitors (SGLT-2 inhibitors) have transformed diabetes management by targeting renal glucose reabsorption. Designed initially as antidiabetic agents, their ability to lower blood glucose levels independently of insulin is well-documented. Beyond glycemic control, emerging research has unveiled their profound cardiorenal benefits. By inhibiting SGLT-2 protein, these drugs enhance glucose excretion in urine, reducing blood glucose levels. This mechanism has translated into significant cardiovascular and renal protection, establishing SGLT-2 inhibitors as pivotal in managing not only diabetes but also cardiovascular and renal diseases. Recent studies have illuminated the broader therapeutic potential of SGLT-2 inhibitors beyond diabetes. Evidence indicates their efficacy in managing heart failure, chronic kidney disease (CKD), and cardiovascular complications in individuals with or without diabetes. This expanded therapeutic landscape has catalyzed a paradigm shift in SGLT-2 inhibitor use, positioning them as key agents in the cardiorenal metabolic continuum. Moreover, their role in the secondary prevention of cardiovascular events and slowing CKD progression in T2DM patients has garnered considerable attention. This consensus-based review aims to offer practical guidance in an algorithmic approach to primary care healthcare professionals to optimize SGLT-2 inhibitors utilization and maximize their benefits. The review seeks to empower clinicians to effectively manage patients who may benefit from SGLT-2 inhibitor therapy by addressing common initiation barriers and optimizing treatment strategies. Additionally, it aims to raise awareness among primary care physicians regarding the multifaceted benefits of these medications and overcome clinical inertia in their adoption into routine clinical practice.

关键词： Sodium-Glucose Cotransporter-2 Inhibitors Cardiorenal Benefits Therapeutic Potential Cardiovascular Protection Primary Care Optimization

Catalytic oxidative desulfurization of gasoline using phosphotungstic acid supported on MWW zeolite

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Frontiers of Chemical Science and Engineering 2020年第4期14卷 546-560页

作者： Hanlu Wang idris Jibrin Xingye Zeng College of Chemical Engineering Guangdong University of Petrochemical TechnologyMaoming 525000China

Catalysts for the desulfurization of gasoline samples were synthesized via the immobilization of well-dispersed phosphotungstic acid(HPW)on Mobil compo-sition of matter-twenty-two(MWW)***-tion results indicated that these catalysts possess a mesoporous structure with the retention of the Keggin structure of immobilized *** reaction para-meters influencing sulfur removal were systematically investigated,including HPW loading,catalyst dosage,temperature,initial S-concentration,molar ratio of oxidant to sulfide(O/S),volume ratio of MeCN to model oil(Ext./oil),and sulfide *** 40 wt-%HPW/MWW catalyst exhibited the highest catalytic activity with 99.6%dibenzothiophene sulfur removal from prepared *** 40 wt-%HPW/MWW catalyst was recycled four times and could be easily ***,as an exploratory study,straight-run-gasoline and fluid catalytic cracking gasoline were employed to accurately evaluate the desulfurization performance of 40 wt-%HPW/*** research provides new insights into the development and application of catalysts for desulfurization of gasoline.

关键词： oxidative desulfurization phosphotungstic acid MWW wet impregnation adsorption energy

Research on the Collaborative Governance of Social Responsibility in Online Audiovisual Enterprises

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