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Hibernation with rhythmicity:the circadian clock and hormonal adaptations of the hibernating Asiatic toads(Bufo gargarizans)

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Integrative Zoology 2022年第4期17卷 656-669页

作者： Zhigang XIE ibrahim m.ahmad Lirong ZUO Feng XIAO Yongpeng WANG Dongming LI Zhejiang Academy of Agricultural Sciences HangzhouChina College of Chemistry and Life Science Zhejiang Normal UniversityJinhuaChina ministry of Education Key Laboratory of molecular and Cellular Biology Key Laboratory of Animal PhysiologyBiochemistry and Molecular Biology of Hebei ProvinceCollege of Life SciencesHebei Normal UniversityShijiazhuangChina

Hibernation is one of the fundamental strategies in response to cold environmental *** hibernation,the endocrine and circadian systems ensure minimal expenditure of energy for *** circadian rhythms of key hormones,melatonin(mT),corticosterone(CORT),triiodothyronine(T3),and thyroxine(T4),and the underlying molecular regulatory mechanisms of hibernation have been well determined in mammals but not in ***,a terrestrial hibernating species,Asiatic toad(Bufo gargarizans),was employed to investigate the plasma CORT,mT,T3,and T4;and the retina,brain,and liver mRNA expression of the core clock genes,including circadian locomotor output cycles kaput(Clock),brain and muscle ARNT-like 1(Bmal1),cryptochrome(Cry)1 and 2,and period(Per)1 and 2,at 7-time points over a 24-h period under acute cold(1 day at 4℃),and hibernation(45 days at 4℃).Our results showed that the circadian rhythms of the core clock genes were rather unaffected by acute cold exposure in the retina,unlike the brain and *** contrast,during hibernation,the liver clock genes displayed significant circadian oscillations,while those in the retina and brain stopped ***,plasma CORT expressed circadian oscillations in both groups,and T3 in acute cold exposure group,whereas T4 and mT did *** results reveal that the plasma CORT and the liver sustain rhythmicity when the brain was not,indicating that the liver clock along with the adrenal clock synergistically maintains the metabolic requirements to ensure basic survival in hibernating Asiatic toads.

关键词： Asiatic toad circadian rhythm clock genes cold exposure hibernation metabolic hormones

Physiological but not morphological adjustments along latitudinal gradients in a human commensal species,the Eurasian tree sparrow

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Integrative Zoology 2023年第5期18卷 891-905页

作者： Qian ZHANG mo LI Yuan YIN Shiyong GE Danjie LI ibrahim m.ahmad Ghulam NABI Yanfeng SUN Xu LUO Dongming LI Hebei Key Laboratory of Animal Physiology Biochemistry and Molecular BiologyCollege of Life SciencesHebei Normal UniversityShijiazhuangChina Key Laboratory for ConservingWildlife with Small Populations in Yunnan Faculty of Biodiversity and ConservationSouthwest Forestry UniversityKunmingChina Ocean College Hebei Agricultural UniversityQinhuangdaoChina Hebei Collaborative Innovation Center for Eco-Environment Hebei Normal UniversityShijiazhuangChina

Human commensal species take advantage of anthropogenic conditions that are less likely to be challenged by the selective pressures of natural *** morphological and physiological phenotypes can therefore dissociate from habitat *** how these species adjust their morphological and physiological traits across latitudinal gradients is fundamental to uncovering the eco-physiological strategies underlying coping ***,we studied morphological traits in breeding Eurasian tree sparrows(ETSs;Passer montanus)among low-latitude(Yunnan and Hunan)and middle-latitude(Hebei)localities in *** then compared body mass;lengths of bill,tarsometatarsus,wing,total body,and tail feather;and baseline and capture stress-induced levels of plasma corticosterone(CORT)and the metabolites including glucose(Glu),total triglyceride(TG),free fatty acid(FFA),total protein,and uric acid(UA).None of the measured morphological parameters varied with latitude except in the Hunan population,which demonstrated longer bills than those in other ***-induced CORT levels significantly exceeded baseline levels and decreased with increasing latitude,but total integrated CORT levels did not vary with *** stress-induced significantly increased Glu levels and decreased TG levels,independent of ***,the Hunan population had significantly higher baseline CORT,baseline and stress-induced FFA levels,but lower UA levels,which differed from other *** results suggest that rather than morphological adjustments,physiological adjustments are mainly involved in coping mechanisms for middle-latitude adaptation in *** is worth investigating whether other avian species also exhibit such dissociation from external morphological designs while depending on physiological adjustments.

关键词： capture stress corticosterone human commensal species latitudinal gradients plasma metabolites

Seasonal variations in gonad morphology and hypothalamic GnRH-I and GnIH in Eurasian Tree Sparrow,a multi-brooded passerine

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Avian Research 2022年第3期13卷 369-378页

作者： Limin Wang Ghulam Nabi Li Zhang Dan Liu mo Li Juyong Li Kaixin Shi ibrahim m.ahmad Yuefeng Wu John C.Wingfield Dongming Li ministry of Education Key Laboratory of molecular and Cellular Biology Key Laboratory of Animal PhysiologyBiochemistry and Molecular Biology of Hebei ProvinceCollege of Life SciencesHebei Normal UniversityShijiazhuang050024China Department of Neurobiology Physiology and BehaviorUniversity of Californi1DavisCAUSA

The hypothalamic-pituitary-gonadal(HPG)axis ubiquitously regulates seasonal reproduction,following the rhythmicity of a suite of environmental *** display prominent seasonal variations in gonad size regulated by two hypothalamic peptides,gonadotropin-releasing hormone-1(GnRH-I)and gonadotropin-inhibiting hormone(GnIH).How multi-brooded avian species adjust GnRH-I and GnIH to regulate gonadal morphology seasonally remains largely ***,we studied the variations in the hypothalamic immunoreactivity(ir)of GnRH-I and GnIH,gonadal proliferation,and apoptosis in a typical multi-brooded species,the Eurasian Tree Sparrow(Passer montanus),across the pre-breeding(PB),first breeding(FB),second breeding(SB),pre-basic molt(Pm),and wintering stages(WS).Our results showed that both sexes had higher preoptic area(POA)-GnRH-I-ir but lower paraventricular nucleus(PVN)-GnIH-ir neurons during the breeding stages(FB and SB)relative to other life-history stages,with no significant differences between two *** testes and ovaries were significantly larger during the breeding *** volume increased during the two broods due to anincreased diameter of seminiferous ***,there were more testicular apoptotic cells in PB and WS stages than in breeding stages,and in PB stage than in Pm *** had higher POA-GnRH-I expression than females during the breeding stages,but both sexes had comparable PVN-GnIH expression throughout the annual *** sexes of the sparrows may undergo a similar pattern of life-history stage-dependent variation in the hypothalamic GnRH-I,GnIH,and gonadal morphology,except that during breeding stages,males may display higher expression of POA-GnRH-I relative to *** higher expression of POA-GnRH-I-ir in breeding male sparrows may be critical for male-dependent parental care.

关键词： Eurasian Tree Sparrow Gonads Hypothalamus Reproduction Seasonality

Effects of constant light and dark conditions on the locomotor activity,body mass,and body temperature rhythms of Eurasian Tree Sparrows(Passer montanus)

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Avian Research 2023年第3期14卷 435-442页

作者： Lirong Zuo ibrahim mahmad Yuanyuan Liu Limin Wang Shu Fang Dongming Li Hebei Key Laboratory of Animal Physiology Biochemistry and Molecular BiologyCollege of Life SciencesHebei Normal UniversityShijiazhuang050024Hebei ProvinceChina Hebei Collaborative Innovation Center for Eco-Environment Hebei Normal UniversityShijiazhuang050024China

Light is an essential environmental cue influencing the endogenous circadian clocks that regulate behavioral and physiological processes in *** extensive research on the circadian rhythms of avian behavior and physiology,the mechanisms by which they adapt and adjust to abnormal photoperiod conditions,such as artificial light,have yet to be fully ***,the circadian rhythms of the body mass,activity,and core and peripheral body temperatures of the Eurasian Tree Sparrow(Passer montanus,ETS)-a diurnal passerine-were examined under three different lighting conditions:constant light(LL),constant darkness(DD),and normal light-dark cycles(LD).Our results showed that the activity,body mass,core,tarsometatarsus,and eye temperatures of the ETSs varied significantly with treatment,time,and the interaction between treatment and time;however,there was no significant change in body mass in response to the interaction between time and *** LD conditions,the ETSs exhibited significant circadian rhythms in activity and core,tarsometatarsus,and eye *** LL conditions,only the core temperature exhibited significant *** DD conditions,there were no significant circadian rhythms in activity,body mass,and eye temperature;however,the core and tarsometatarsus temperatures remained *** results indicate that the core body temperature rhythm of ETS is endogenous and can be maintained under abnormal *** contrast,the activity and body surface temperature,uncoupled from the core body temperature under abnormal photoperiod conditions,strongly depend on *** results differ from those of other diurnal avian species,suggesting a unique coping mechanism of ETS in response to an abnormal photoperiod.

关键词： Eurasian Tree Sparrow Activity Body mass Body temperature Circadian rhythm

Solution approximations for a mathematical model of relativistic electrons with beta derivative

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Applied mathematics(A Journal of Chinese Universities) 2024年第3期39卷 469-485页

作者： ibrahim Yalcinkaya Orkun Tasbozan Ali Kurt Hijaz ahmad Department of mathematics and Computer Sciences Faculty of ScienceNecmettin Erbakan UniversityKonyaTurkey Department of mathematics Faculty of Science and LiteratureHatay Mustafa Kemal UniversityHatayTurkey Department of mathematics Faculty of SciencePamukkale UniversityDenizliTurkey Near East University Operational Research Center in HealthcareTRNC Mersin 10Nicosia99138Turkey Department of mathematics Faculty of ScienceIslamic University of MadinahMadinahSaudi Arabia

The main aim of this paper is to obtain the exact and semi-analytical solutions of the nonlinear Klein-Fock-Gordon(KFG)equation which is a model of relativistic electrons arising in the laser thermonuclear fusion with beta *** this purpose,both the modified extended tanh-function(mETF)method and the homotopy analysis method(HAm)are *** applying the mETF the chain rule for beta derivative and complex wave transform are used for obtaining the exact *** advantage of this procedure is that discretization or normalization is not *** applying the mETF,the exact solutions are ***,by applying the HAm semi-analytical results for the considered equation are *** HAm?curve gives us a chance to find the suitable value of the for the convergence of the solution ***,comparative graphical representations are given to show the effectiveness,reliability of the *** results show that the m ETF and HAm are reliable and applicable tools for obtaining the solutions of non-linear fractional partial differential equations that involve beta *** study can bring a new perspective for studies on fractional differential *** the other hand,it can be said that scientists can apply the considered methods for different mathematical models arising in physics,chemistry,engineering,social sciences and *** involves fractional *** the results may cause a new insight who studies on relativistic electron modelling.

关键词： Klein-Fock-Gordon(KFG)equation beta derivative semi-analytical solution exact solution

Analysis of cerium substitution in Co-Sr based spinel ferrites for high frequency application

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Journal of Rare Earths 2024年第9期42卷 1755-1763,I0005页

作者： Laura Khudaysh Inas A.Ahmed Syeda Rabia Ejaz Sajjad ahmad Khan Yasir A.Haleem mohamed m.ibrahim mahmood Ali Hafiz muhammad Tahir Farid Zeinhom m.El-Bahy Department of Physics Faculty of ScienceJazan UniversityJazan45142Saudi Arabia Department of Chemistry Faculty of ScienceKing Khalid UniversityAbha62224Saudi Arabia Department of Physics The Government Sadiq College Women UniversityBahawalpur63100Pakistan Institute of Physics Khwaja Fareed University of Engineering and Information TechnologyRahim Yar Khan64200Pakistan Department of Chemistry College of ScienceTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Centre of Excellence in Solid State Physics University of the PunjabLahorePakistan Department of Physics Government CollegeTaunsa Sharif32200Pakistan Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr City11884CairoEgypt

Spinel ferrites exhibit exceptional magnetic properties,making them a distinctive class of magnetic *** sol-gel technique was utilized for the synthesis of spinel ferrites with the chemical formula Co_(0.6)Sr_(0.4)Ce_(x)Fe_(2-x)O_(4). Following that,a comprehensive X-ray diffraction analysis unveiled the crystalline cubic structure of the synthesized *** the utilization of the m-H loop approach,the ferromagnetic attributes of ferrites were assessed,and the assimilation of rare earth elements led to substantial enhancements in saturation magnetization,remanence,and *** ferrites with a high concentration of rare earth elements have improved direct current resistivity and activation *** logarithm of a material's resistance increased from 5.29 to 8.12 Ω·cm as cerium is *** a change in the amount of cerium,the activation energy goes up from 0.19 to *** changing the frequency from 5.5 to 9.5 GHz,the dielectric characteristics were *** the frequency goes up,the dielectric constant goes *** ferrites that have been made better in every way can be used in high-frequency applications.

关键词： Activation energy DC electrical resistance Remanence magnetization Cobalt strontium spinel ferrites High frequency application Rare earths

An Adaptive Hate Speech Detection Approach Using Neutrosophic Neural Networks for Social media Forensics

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Computers, materials & Continua 2024年第4期79卷 243-262页

作者： Yasmine m.ibrahim Reem Essameldin Saad m.Darwish Department of Information Technology Institute of Graduate Studies and ResearchAlexandria UniversityAlexandria21526Egypt Faculty of Computers and Information Technology Egyptian E-Learning University(EELU)Giza12611Egypt Faculty of Computers and Data Science Alexandria UniversityAlexandria21554Egypt

Detecting hate speech automatically in social media forensics has emerged as a highly challenging task due tothe complex nature of language used in such platforms. Currently, several methods exist for classifying hatespeech, but they still suffer from ambiguity when differentiating between hateful and offensive content and theyalso lack accuracy. The work suggested in this paper uses a combination of the Whale Optimization Algorithm(WOA) and Particle Swarm Optimization (PSO) to adjust the weights of two multi-Layer Perceptron (mLPs)for neutrosophic sets classification. During the training process of the mLP, the WOA is employed to exploreand determine the optimal set of weights. The PSO algorithm adjusts the weights to optimize the performanceof the mLP as fine-tuning. Additionally, in this approach, two separate mLP models are employed. One mLPis dedicated to predicting degrees of truth membership, while the other mLP focuses on predicting degrees offalse membership. The difference between these memberships quantifies uncertainty, indicating the degree ofindeterminacy in predictions. The experimental results indicate the superior performance of our model comparedto previous work when evaluated on the Davidson dataset.

关键词： Hate speech detection whale optimization neutrosophic sets social media forensics

Enhancing mild Cognitive Impairment Detection through Efficient magnetic Resonance Image Analysis

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Computers, materials & Continua 2024年第8期80卷 2081-2098页

作者： Atif mehmood Zhonglong Zheng Rizwan Khan ahmad Al Smadi Farah Shahid Shahid Iqbal mutasem K.Alsmadi Yazeed Yasin Ghadi Syed Aziz Shah mostafa m.ibrahim Department of Computer Science and Technology Zhejiang Normal UniversityJinhua321002China Zhejiang Institute of Photoelectronics&Zhejiang Institute for Advanced Light Source Zhejiang Normal UniversityJinhua321004China Department of Data Science and Artificial Intelligence Zarqa UniversityZarqa13100Jordan School of Chemical and Environmental Engineering College of ChemistryChemical Engineering andMaterials ScienceSoochow UniversitySuzhou215123China Department of management Information Systems College of Applied Studies and Community ServiceImam Abdulrahman Bin Faisal UniversityDammam32244Saudi Arabia Department of Computer Science Al Ain UniversityAbu Dhabi999041United Arab Emirates Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61519Egypt Healthcare Technology and Innovation Theme Faculty Research Centre for Intelligent HealthcareCoventry UniversityCoventryCV48BWUK

Neuroimaging has emerged over the last few decades as a crucial tool in diagnosing Alzheimer’s disease(AD).mild cognitive impairment(mCI)is a condition that falls between the spectrum of normal cognitive function and ***,previous studies have mainly used handcrafted features to classify mCI,AD,and normal control(NC)*** paper focuses on using gray matter(Gm)scans obtained through magnetic resonance imaging(mRI)for the diagnosis of individuals with mCI,AD,and *** improve classification performance,we developed two transfer learning strategies with data augmentation(i.e.,shear range,rotation,zoom range,channel shift).The first approach is a deep Siamese network(DSN),and the second approach involves using a cross-domain strategy with customized *** performed experiments on the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset to evaluate the performance of our proposed *** experimental results demonstrate superior performance in classifying the three binary classification tasks:NC ***,NC ***,and mCI ***,we achieved a classification accuracy of 97.68%,94.25%,and 92.18%for the three cases,*** study proposes two transfer learning strategies with data augmentation to accurately diagnose mCI,AD,and normal control individuals using Gm *** findings provide promising results for future research and clinical applications in the early detection and diagnosis of AD.

关键词： Alzheimer’s disease mild cognitive impairment normal control transfer learning classification augmentation

Novel synthesis of stabilized Bi1-x-yGdxDyyO1.5 solid electrolytes with enhanced conductivity for intermediate temperature solid oxide fuel cells（SOFCs）

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Journal of Rare Earths 2024年第10期42卷 1903-1911页

作者： Ahmed H.ibrahim Yehia m.Abbas H.A.Ayoub marwa H.Ali mustafa Aldoori materials Science Laboratory Physics DepartmentFaculty of ScienceSuez Canal University ministry of Higher Education and Scientific Research Aliraqia University

Herein,we report the synthesis of a Dy-Gd co-doped cubic phase-stabilized Bi2O3solid electrolyte system via solid-state processing under atmospheric *** with Dy3+and Gd3+has been observed to significantly enhance the densification process during sintering for stabilization purposes,thereby improving the electrical properties of δ-Bi2O3-type *** synthesized ceramics were characterized using X-ray diffraction（XRD）,field emission scanning electron microscopy-energy dispersive X-ray spectroscopy（FESEm-EDX）,thermal gravimetry/differential thermal analysis（TG/DTA）,and the four-point probe technique（4PPT）.XRD analysis reveals that the samples Bi1-x-yGdxDyyO1.5（y=0.05/x=0.05,0.10,0,15,and 0.20,and x=0.05/y=0.10,0.15,and 0.20） exhibit a stable face-centered cubic δ-phase and a mixed-phase crystallographic *** XRD analysis of the stabilized δ-phase suggests that the prepared oxides show a face-centered cubic（FCC） structure with a space group of *** micrographs reveal that the composition Bi0.90Gd0.05Dy0.05O1.5has no significant ***,an evident increase in the pore formation is observed as the amount of Gd2O3increases until it reaches 20%.This finding suggests that dense pellets are formed during the sintering process at 900-1000℃.The DTA analyses were performed to verify the phase stability,which agrees with the XRD *** electrochemical performance of the synthesized Dy-Gd co-doped Bi2O3solid electrolyte system was evaluated and analyzed in detail by using the electrochemical impedance spectroscopy（EIS） technique,Based on EIS and conductivity measurements,Bi0.75Gd0.20Dy0.05O1.5exhibits the lowest activation energy of 0.519 eV and the highest conductivity value of 0.398 S/cm at 627℃compared to the other samples;this composition can be used as a solid electrolyte for intermediatetemperature solid oxide fuel cells（SOFCs）.

关键词： Electrochemical impedance spectroscopy (EIS) Fast Fourier transform (FFT) Rare earths Rietveld Solid oxide fuel cells (SOFCs) Solid-state processing