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Selected Aspects of Camel Immune System and Immune Responses

Open Journal of Veterinary Medicine 2021年第6期11卷 177-211页

作者： Saeed Y. Al Ramadan Kazem T. Al-Moh.mmed Salem ibrahim h. alshubaith Ah.ed M. Al-Ali Salah.Aboh.laika Moh.mmed S. Moqbel Ah.ed M. Alluwaimi Department of Anatomy College of Veterinary Medicine King Faisal University Al-Ahsaa Saudi Arabia Animal Resources Management Ministry of Environment Water and Agriculture Al-Ahsaa Saudi Arabia Environmental h.alth.Department Al-Ahsaa Municipality Al-Ahsa Saudi Arabia Central Biotech.ology Laboratory Veterinary Teaching Hospital College of Veterinary Medicine King Faisal University Al-Ahsaa Saudi Arabia Clinical Ph.rmacology Department Qatif Central Hospital Ministry of Health Saudi Arabia Department of Microbiology and Parasitology College of Veterinary Medicine King Faisal University Al-Ahsaa Saudi Arabia

Th. camel economy is of considerable importance for arid countries. In th. last decade, studies about camel immune system and immune responses h.ve recorded increasing interest. h.wever, drawing a compreh.nsive pictur... 详细信息

Th. camel economy is of considerable importance for arid countries. In the last decade, studies about camel immune system and immune responses have recorded increasing interest. However, drawing a comprehensive picture of the camel immune system remains far from reached. A major part of this review is to cover the studies of the primary and secondary immune organs and the markers of the camel immune cells and certain lymphoid tissues. At the same time, immune responses to different diseases and the nature of effective immunity were included, with an emphasis on the most important zoonotic diseases in camels such as MERS CoV;brucellosis. New findings on the diversity mechanisms of camel immunoglobulin genes were addressed. However, detail of the mechanism of MHC-restricted cellular immunity and the mechanism of B lymphocyte activation in camels await further attention. Interestingly, the gross and the histological structure of the lymphoid tissues of the camel’s thymus, tonsils, and peyer’s patches have indicated significant differences from other animals in terms of structure and function. The most peculiar CD expression, such as LPAM-I, MAdCAM-1 and CX3CR1, in certain camel cells and tissues refers to possible extraordinary mechanisms of immune hemostasis in camel in comparison to oth.r ruminants. Th. widely applied immunodiagnostic tech.iques to control camel diseases and to assist in improving th. camel resistance were considered. Extensive studies of th. camel immune system were greatly h.mpered by lack of specific reagents to camel markers and low funds in th. field of camel i

关键词： Camel CX3CR1 h.avy Ch.in Antibody MERS-CoV Peyer’s Patch.s

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