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Cost of Medical Treatment for Primary Open-Angle Glaucoma in Relation to Patients’ Income and Its Impact on the Prognosis of the Disease, in Bouaké University Hospital

Atmospheric and Climate Sciences（大气和气候科学） 2024年第3期 287页

作者： ibrahim Badawi

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Open Journal of Ophthalmology 2024年第1期14卷 8-17页

作者： Yves Ouattara Liliane Ella Godé Zana Diabaté Franck Hermann Koffi Mamadou Korka Diallo Philippe Emile France Koffi Bilé Diomandé François Gossé ibrahim Abib Diomandé Ophthalmology Department of Bouaké University Hospital (CHU de Bouaké) Bouaké C&#244te d’Ivoire

Introduction: Medical treatment for POAG is continuous and lifelong treatment. The aim of this study was to evaluate the relationship between the cost of this treatment and patients’ income and the impact of this relationship on treatment compliance. Materials and Methods: Prospective cross-sectional study with a descriptive aim covering sociodemographic data, average incomes, and direct and indirect costs of treatment of 57 patients followed for POAG during the period from January 1, 2012, to December 31, 2016 (5 years). Results: The patients were aged 25 to 77 years (mean = 54.4 years) with a male predominance (sex ratio = 1.5). Retirees were the most represented (26.32%), followed by workers in the informal sector (14.04%) and housewives (12.28%). Patients who had an annual income less than or equal to 900,000 CFA francs (€1370.83) per year represented 56.14% and those who did not have health coverage represented 57.89%. The treatment was monotherapy (64.91%), dual therapy (31.58%) or triple therapy (3.05%) and the average ratio of “annual cost of treatment to annual income” was 0.56 with for maximum 2.23 and 0.02 as minimum. Patients who considered the cost of treatment unbearable for their income represented 78.95%. Conclusion: Prevention of blindness due to glaucoma requires early detection but also the establishment of health coverage mechanisms to improve compliance with medical treatment. In addition, consideration should be given to the development of glaucoma surgery in our country, the indication of which could be the first intention in certain patients, considering for those patients, the geographical and financial accessibility of medical treatment. .

关键词： Primary Open-Angle Glaucoma Treatment Cost Medical Treatment Income Blindness

The Problem of Rehospitalisation for Heart Failure at the Cardiology Department of the Hôpital National Ignace Deen

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World Journal of Cardiovascular Diseases 2024年第9期14卷 539-546页

作者： Samoura Sana Bah Mamadou Bassirou Soumaoro Morlaye Samoura Aly Koné Alpha Sylla ibrahima Sory Samoura Sekouba Barry ibrahim Sory Balde Elhadj Yaya Balde Mamadou Dadhi Hopital Sino-Guineen Conakry Guinea Hopital National Ignace Deen Conakry Guinea Hopital de Lamiti Sino-Guineenne Conakry Guinea

Introduction: Despite current therapeutic advances, heart failure in sub-Saharan Africa remains a common, serious and costly disease, particularly due to rehospitalizations. The objective of this work was to determine the proportion of rehospitalizations for heart failure and to identify etiological factors. Methodology: This was a retrospective descriptive study with a duration of 8 months from April 1 to November 30, 2021. This study included all patients rehospitalized in the department for Heart Failure and who agreed to participate in our study. Results: During the period of our study, 437 patients were hospitalized in the HF department, among which we collected 126 cases of rehospitalization for HF with a frequency of 28.83%. The mean age of our patients was 46.32 ± 18.98 years with the extremes of 15 to 84 years. The most affected age group was between 35 and 44 years old in 24 cases, i.e. a frequency of 19%. We observed a female predominance of 64 cases, i.e. a frequency of 50.8% compared to 62 cases, i.e. a frequency of 49.2% with a sex ratio (M/F) equal to 0.96. 98 cases of our patients, i.e. a frequency of 77.8%, were mutual insurance companies who felt they had the necessary support from those around them. In our sample, the underlying heart disease was mainly represented by valvular heart disease in 59 cases, followed by hypertensive heart disease in 42 cases with the respective frequencies of 46.82% and 33.33%. The majority of our patients were rehospitalized (1 - 3) times after a first episode of HF flare-up in 117 cases or 92.9%. Irregularity at control and therapeutic break were the most common decompensation factors with frequencies of 75.8% and 74.2% respectively. The majority of our patients were rehospitalized (1 - 3) times after a first episode of HF flare-up in 117 cases or 92.9%. Irregularity at control and therapeutic break were the most common decompensation factors with frequencies of 75.8% and 74.2% respectively. Conclusion: It appears in

关键词： Heart Failure Rehospitalisation Valvular Heart Disease

Projected Changes in the Climate Zoning of Côte d’Ivoire

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Atmospheric and Climate Sciences 2024年第1期14卷 62-84页

作者： Mamadou Diarrassouba Adama Diawara Assi Louis Martial Yapo Benjamin Komenan Kouassi Fidèle Yoroba Kouakou Kouadio Dro Touré Tiemoko Dianikoura ibrahim Koné Arona Diedhiou Laboratory of Sciences Matter Environment and Solar Energy (LASMES) University Félix Houphou&#235t-Boigny Abidjan C&#244te d’Ivoire Geophysical Station of Lamto (GSL) N’douci C&#244te d’Ivoire Laboratory of Fundamental and Applied Physics University Nangui Abrogoua Abidjan C&#244te d’Ivoire Université Grenoble Alpes (UGA) Institut des Géosciences de l’Environnement (IGE) Institut de Recherche pour le Développement (IRD) Centre National de Recherche Scientifique (CNRS) Institut National Polytechnique (INP) Grenoble France African Centre of Excellence on Climate Change Biodiversity and Sustainable Agriculture (ACE-CCBAD)/University Felix Houphou&#235t-Boigny (UFHB) Abidjan C&#244te d’Ivoire

This study assesses the projected changes in the climate zoning of Côte d’Ivoire using the hierarchical classification of principal components (HCPC) method applied to the daily precipitation data of an ensemble of 14 CORDEX-AFRICA simulations under RCP4.5 and RCP8.5 scenarios. The results indicate the existence of three climate zones in Côte d’Ivoire (the coastal, the centre and the north) over the historical period (1981-2005). Moreover, CORDEX simulations project an extension of the surface area of drier climatic zones while a reduction of wetter zones, associated with the appearance of an intermediate climate zone with surface area varying from 77,560 km2 to 134,960 km2 depending on the period and the scenario. These results highlight the potential impacts of climate change on the delimitation of the climate zones of Côte d’Ivoire under the greenhouse gas emission scenarios. Thus, there is a reduction in the surface areas suitable for the production of cash crops such as cocoa and coffee. This could hinder the country’s economy and development, mainly based on these cash crops.

关键词： Climate Projection Climate Zone Principal Component Analysis Hierarchical Classification on Principal Components CORDEX Côte d’Ivoire

Long-Term Mortality of Children with Congenital Heart Disease Admitted to the Departmental University Hospital of Borgou/Alibori from 2011 to 2022

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World Journal of Cardiovascular Diseases 2024年第3期14卷 166-186页

作者： Serge Hugues Mahougnon Dohou Nicolas Hamondji Amegan Ahmad ibrahim Gérard Médétinmè Kpanidja Chabi Olaniran Alphonse Biaou Houétondji Léopold Codjo Cardiology Teaching and Research Unit (CHUD-B/A) Faculty of Medicine University of Parakou Parakou Benin É cole de Sant&#233 Publique de l&#8217Universit&#233 de Montr&#233al (ESPUM) Montr&#233al Qu&#233bec Canada Paediatrics and Medical Genetics Teaching and Research Unit (CHUD-B/A) Faculty of Medicine University of Parakou Parakou Benin Regional Institute of Public Health University of Abomey-Calavi Cotonou Benin Cardiology Department Faculty of Health Sciences University of Abomey-Calavi Cotonou Benin

Background: Congenital heart disease is a public health issue due to its incidence and mortality rate. The aim of this study was to investigate the long-term mortality of children with congenital heart disease admitted to the Departmental University Hospital of Borgou/Alibori (CHUD-B/A) from 2011 to 2022. Methods: This descriptive longitudinal study with analytical aims covered 11 years (April 1, 2011 to December 31, 2022). It consisted of a review of the records of children under 15 years of age with echocardiographically confirmed congenital heart disease. This was followed by an interview with the parents to assess the children’s current condition. Data were entered using Kobocollect software and analyzed using R Studio 4.2.2. software. Results: A total of 143 complete files were retained. The median age at diagnosis was 14 months (IIQ: Q1 = 4;Q3 = 60) with a range of 2 days and 175 months, and the sex-ratio (M/F) was 0.96. Left-to-right shunts were the most frequent cardiopathy group (62.9%). Only 35 children (24.5%) benefited from restorative treatment. The mortality rate was 31.5%. Median survival under the maximum bias assumption was 114 months and 216 months under the assumption of minimum bias. Survival was significantly better in children with right-to-left shunts (p = 0.0049) under the assumption of minimum bias. The death risk factors were: age at diagnosis less than 12 months (aHR = 7.58;95% CI = 3.36 - 17.24;p Conclusion: The long-term mortality of congenital heart disease is high and favoured by the absence of restorative treatment. Local correction of congenital heart disease and medical follow-up will help to reduce this mortality.

关键词： Congenital Heart Disease Long-Term Mortality Parakou Risk Factors

Ethnobotanical and Phytochemical Study of Medicinal Plants Sold in the Markets of the City of N’Djamena

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Advances in Biological Chemistry 2024年第4期14卷 121-144页

作者： Djibrine Adoum Oumar Teissir ibrahim Abakar Hama Cissé Salomon Madjitoloum Betoloum Adama Sawadogo Jean-Ulrich Muandze Nzambe Elisée Mbayngone Abdelsalam Tidjani Aly Savadogo Natural Substances Research Laboratory (NSRL) Faculty of Exact and Applied Sciences (FEAS) University of NDjamena Chad Tchad Laboratory of Applied Biochemistry and Immunology (LABI) Joseph KI-ZERBO University Ouagadougou Burkina Faso Food Science and Nutrition Research Laboratory (FSNRL) Faculty of Human Health Sciences (FHHS) University of NDjamena Chad Tchad

The use of medicinal plants occupies an important place in traditional Chadian medicine, this study was carried out with the aim of listing the medicinal plants sold in the markets of the city of N’Djamena, and knowledge of the medicinal flora Chad, such as the leaves of Guiera senegalensis in Arabic called Khibeche, the roots of Cassia occidentalis called Am kwala-Kinkéliba in Arabic;the bark of Khaya senegalensis (Desv) A. Juss called Muraї in Arabic and the seeds of Trigonella foenum-graecum called Helbé in Arabic in order to treat the most frequently cited diseases such as malaria, the common cold, mother and newborn care, and typhoid. Ethnobotanical surveys were conducted from September to December 2022, in three markets in the city of N’Djamena, based on individual interviews using a semi-structured questionnaire, with 30 herbalists and traditional practitioners. Phytochemical screening analyses of the organs of four plants were carried out in the chemistry and biology laboratory of the Faculty of Exact and Applied Sciences (FSEA) following a standard protocol established by [1] and slightly modified by [2] [3]. The results of the surveys identified 68 species divided into fifty-five (55) genera and twenty-seven (27) families, the most represented of which were Caesalpiniaceae (10 species), Mimosaceae (5 species) and Combretaceae (4 species). The leaves were the most commonly used parts (43%), with decoction (70%) the most frequently used method of preparation. The oral route was the most popular with 73% of recipes. The phytochemical study revealed a wealth of secondary metabolites such as Trapezoidal Sterols, Alkaloids, Tannins, Flavonoids, Free Quinones, Anthocyane, Anthraquinones, Saponosides and Heterosides. These results can be considered as a source of information for scientific research in the field of phytochemistry and pharmacology.

关键词： Chad (N’Djamena) Medicinal Plants Ethnobotany Screening Phytochemistry

Hematological Alterations in an Eastern Sudanese Chronic Kidney Disease Patient Population

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Open Journal of Urology 2024年第6期14卷 359-367页

作者： Mohammed Omer Abaker Gibreel Sundus Kamal ibrahim Wijdan Abdel Aziz Hassan Manar Yahia Mahjoub Leyla Mohammed Kheir Hamid Hibatellah Majzoub Abbas Nuha Fouzi Mohammed Secretariat of Academic Affairs Port Sudan Ahlia University Port Sudan Sudan Department of Hematology and Immunohematology College of Graduate Studies Port Sudan Ahlia University Port Sudan Sudan

Background: Chronic Kidney Disease (CKD), associated with a slow and progressive loss of kidney function over a period of several years, is an important clinical disaster with an increasing rate of morbidity and mortality especially in the least developed countries. Many hematological parameters are thought to alter dramatically during the course of the disease. These include white blood cells, red blood cells, and platelets. Methods: We tried, retrospectively, to evaluate the peripheral blood hematological alterations in a group of patients undergoing hemodialysis in an eastern Sudan dialysis center to add local medical information. Results: Anemia (Low hemoglobin and hematocrit) was detected in 94% of the patients’ group. Mean Erythrocyte count (3.32vs.4.76 (×109/L)), Hemoglobin concentration (9.4vs.13 (g/dl)), Hematocrit (28.7vs.38.7 (L/L)) and platelet count (296 vs. 238 (×109/L)) were significantly lower in the patients’ group than in the control group (P-values Conclusion: Five out of eight studied parameters (Red cell count, hemoglobin, hematocrit, mean cell hemoglobin concentration, and platelets count) have shown a significant alteration in CKD patients. As the complete blood count (CBC) test is the most utilized test in clinical laboratory practice, these alterations may be considered as early indicators for CKD. Furthermore, all patients with CKD must be routinely checked for these alterations.

关键词： Chronic Kidney Disease Chronic Renal Failure Hematological Alterations CBC Eastern Sudan Hemodialysis

Modular-integrative modeling: a new framework for building brain models that blend biological realism and functional performance

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National Science Review 2024年第05期 13-16页

作者： Mario Senden Sacha J.van Albada Giovanni Pezzulo Egidio Falotico ibrahim Hashim Alexander Kroner Anno C.Kurth Pablo Lanillos Vaishnavi Narayanan Cyriel Pennartz Mihai A.Petrovici Lea Steffen Tonio Weidler Rainer Goebel Department of Cognitive Neuroscience Maastricht University Maastricht Brain Imaging Centre Maastricht University Institute of Neuroscience and Medicine(INM-6) and Institute for Advanced Simulation(IAS-6) and JARA-Institut Brain Structure-Function Relationships(INM-10) Jülich Research Center Institute of Zoology University of Cologne Institute of Cognitive Sciences and Technologies The Bio Robotics Institute Scuola Superiore Sant'Anna RWTH Aachen University Donders Institute for Brain Cognition and BehaviorRadboud University Cognitive and Systems Neuroscience Group Swammerdam Institute for Life Sciences University of Amsterdam Department of Physiology University of Bern FZI Research Center of Information Technology

To cope with the immense complexity of the brain, neuroscientific research often focuses on isolated brain structures or circumscribed perceptual, cognitive or motor functions [1]. This reductionist approach overlooks the intricate and multifaceted interplay among various structural and functional *** instance, even simple movements require the coordinated activation of numerous neuronal populations across multiple brain regions [2].

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Effect of Aging on the Toughness of Austenitic and Duplex Stainless Steel Weldments

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Journal of Materials Science & Technology 2010年第9期26卷 810-816页

作者： Omyma Hassan ibrahim ibrahim Soliman ibrahim Tarek Ahmed Fouad Khalifa Metallurgy Dept. Nuclear Research CentreAtomic Energy Authority(Egypt) Nuclear Safety Centre Atomic Energy Authority(Egypt) Shoubra Faculty of Engineering Benha University

In the present study,the effect of aging heat treatment at 650,750,and 850？C on the impact toughness of 316L austenitic stainless steel,2205 duplex stainless steel and their weldments has been *** process was conducted using the TIG（tungsten inert gas） welding *** impact testing,at room temperature,was employed to determine the effect of aging treatment on the impact properties of investigated *** treatment resulted in degradation in the impact toughness as demonstrated by the reduction in the impact fracture energy and deformation parameters（strain hardening capacity,fracture deffection,and crack initiation and propagation energy）.The degree of embrittlement was more noticeable in duplex stainless steel parent and weld-metal than in 316L stainless steel and became greater with the increase of aging *** degradation in impact toughness was discussed in relation to the observed precipitation of the intermetallic sigma phase in the microstructure of the stainless steel weldments and the corresponding fracture surface morphology.

关键词： Austenitic and duplex stainless steels Aging Instrumented impact Toughness

NEW POLY(METHACRYLATE)S CONTAINING OXIME ESTERS MOIETIES BASED ON CYCLOHEXANON AND CYCLOPENTANON

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Chinese Journal of Polymer Science 2008年第4期26卷 443-454页

作者： ibrahim Erol Afyon Kocatepe Universty Faculty of Science and Arts Department of ChemistryAfyonkarahisarTurkey

The synthesis of two new methacrylates such as 2-[(cyclohexylideneamino)oxy]-2-oxoethyl methylacrylate (CHOEMA)and 2-[(cyclopentylideneamino)oxy]-2-oxoethyl methylacrylate(CPOEMA)are *** monomers produced from the reaction of corresponding cyclohexanone O-(2-chloroacetyl)oxime and cyclopentanone O-(2- chloroacetyl)oxime with sodium methacrylate was polymerized in 1,4-dioxane solution at 65℃using AIBN as an initiator. The monomers and their polymers were characterized by IR,~1H- and ^(13)C-NMR spec...

关键词： Methacrylate Oxime esters Activation energy Thermal decompositionv Biological activitiy