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World Journal of Emergency Medicine 2022年第5期13卷 422-424页

作者： ian Zhirui Hong R Ponampalam Department of Emergency Medicine Singapore General Hospital169608Singapore

Dear editor,Human exposure to hydrocarbons(HCs)is unavoidable given their wide usage in a variety of common *** chloride(EC),a type of halogenated HC,has been used in the production of pharmaceuticals,dyes,and other chemicals used for industrial purposes.[1,2]EC was used as an anesthetic induction agent in the early 1900s.[3]Although its use as an inhalational agent has fallen out of favour,EC is still used as a topical pain medication today.[4]

关键词： hydrocarbons agent editor

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Unconventional Bose–Einstein Condensations from Spin-Orbit Coupling

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Chinese Physics Letters 2011年第9期28卷 217-220页

作者： WU Cong-Jun ian Mondragon-Shem ZHOU Xiang-Fa Department of Physics University of CaliforniaSan DiegoCA 92093 Instituto de Física Universidad de AntioquiaAA 1226MedellínColombia Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026

According to the"no-node"theorem,the many-body ground state wavefunctions of conventional Bose–Einstein condensations(BEC)are positive-definite,thus time-reversal symmetry cannot be spontaneously *** find that multi-component bosons with spin-orbit coupling provide an unconventional type of BECs beyond this *** focus on a subtle case of isotropic Rashba spin-orbit coupling and the spin-independent *** the limit of the weak confining potential,the condensate wavefunctions are frustrated at the Hartree–Fock level due to the degeneracy of the Rashba *** zero-point energy selects the spin-spiral type condensate through the"order-from-disorder"*** a strong harmonic confining trap,the condensate spontaneously generates a half-quantum vortex combined with the skyrmion type of spin *** both cases,time-reversal symmetry is spontaneously *** phenomena can be realized in both cold atom systems with artificial spin-orbit couplings generated from atom-laser interactions and exciton condensates in semi-conductor systems.

关键词： interaction mechanism Einstein

Sarcomas - the model for multidisciplinary care in cancer

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Journal of Cancer Metastasis and Treatment 2021年第1期7卷 399-403页

作者： ian Judson Emeritus Professor of Cancer Pharmacology The Institute of Cancer ResearchSuttonSurrey SM25NGUK

Sarcomas were one of the first cancers for which multidisciplinary clinics and team meetings were set up,acknowledging the need for all the diagnostic and treatment disciplines to be involved in the clinical decision-making *** is amply demonstrated by the papers chosen for this special issue of the Journal of Cancer Metastasis and Treatment,which includes articles on basic biology,translational research,pathology,surgery and survivorship.

关键词： clinical Cancer surgery

Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence

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World Journal of Gastroenterology 2006年第39期12卷 6391-6396页

作者： PO Zhao Xin Mao ian C Talbot Department of Pathology Chinese PLA General Hospital Beijing 100853 China Academic Department of Pathology St. Mark's Hospital Cancer Research UK Colorectal Cancer Unit Harrow HA1 3UJ London United Kingdom

AIM： To study the correlation between the patterns of subcellular expression of p16 and CDK4 in colorectal epithelia in the normal-adenoma-carcinoma sequence.METHODS： Paraffin sections of 43 cases of normal colorectal epithelia and corresponding adenomas as well as carcinomas were analysed immunocytochemically for subcellular expression of p16 and CDK4 proteins.RESULTS： Most carcinomas showed more cytoplasmic overexpression for p16 and CDK4 than the adenomas from which they arised or the adjacent normal mucosa. Most normal or non-neoplastic epithelia showed more p16 and CDK4 expression in the nucleus than their adjacent adenomas and carcinomas. There was a significant difference between the subcellular expression pattern of p16 and CDK4 in normal-adenoma-carcinoma sequence epithelia （P 〈 0.001）. Neither p16 nor CDK4 subcellular patterns correlated with histological grade or Dukes＇ stage.CONCLUSION： Interaction of expression of p16 and CDK4 plays an important role in the Rb/p16 *** of p16 and CDK4 in the cytoplasm, as well as loss expression of p16 in the nucleusmighlc be important in the evolution of colorectal carcinoma from adenoma and, of adenoma from normal epitheiia.

关键词： Colorectal neoplasm p16 CDK4 Immunocytochemistry

Porosity of bimodal and trimodal sediment mixtures

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International Journal of Sediment Research 2022年第2期37卷 258-271页

作者： Chamil Perera Weiming Wu ian Knack Department of Civil and Environmental Engineering Clarkson University

This study focuses on the prediction of the porosity of nonuniform sediment mixtures,considering the effects of particle packing.A random particle packing model has been developed for the porosity of bimodal mixtures by extending the existing random particle filling *** in the developed model are calibrated by fitting the model to measured data for a variety of bimodal mixtures,including spherical glass particles,rounded quarry grains,and natural *** model coefficients are found to be functions of the diameter ratio of coarse and fine particles,separately for spherical glass particles and natural sediments due to differences in particle *** bimodal mixture model is then extended to trimodal particle mixtures in three approaches:two based on serial packing and one based on random *** models are tested against experimental data of six trimodal mixtures with spherical glass *** results show that the random packing model and the fine-medium-coarse particle serial packing model predict well the observed trimodal mixture porosities.

关键词： Porosity Particle filling Particle packing Bimodal mixture Trimodal mixture

Power maximization of variable-speed variable-pitch wind turbines using passive adaptive neural fault tolerant control

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Frontiers of Mechanical Engineering 2017年第3期12卷 377-388页

作者： Hamed HABIBI Hamed RAHIMI NOHOOJI ian HOWARD Faculty of Science and Engineering School of Civil and MechanicalEngineering Curtin University Perth Australia

Power maximization has always been a practical consideration in wind turbines. The question of how to address optimal power capture, especially when the system dynamics are nonlinear and the actuators are subject to unknown faults, is significant. This paper studies the control methodology for variable-speed variable-pitch wind turbines including the effects of uncertain nonlinear dynamics, system fault uncertainties, and unknown external disturbances. The nonlinear model of the wind turbine is presented, and the problem of maximizing extracted energy is formulated by designing the optimal desired states. With the known system, a model-based nonlinear controller is designed; then, to handle uncertainties, the unknown nonlinearities of the wind turbine are estimated by utilizing radial basis function neural networks. The adaptive neural fault tolerant control is designed passively to be robust on model uncertainties, disturbances including wind speed and model noises, and completely unknown actuator faults including generator torque and pitch actuator torque. The Lyapunov direct method is employed to prove that the closed-loop system is uniformly bounded. Simulation studies are performed to verify the effectiveness of the proposed method.

关键词： wind turbine nonlinear model maximum power tracking passive fault tolerant control adaptive neural control

Emulsion cold mix asphalt in the UK: A decade of site and laboratory experience

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第4期6卷 359-365页

作者： Dennis Day ian Michael Lancaster Dougie McKay Nynas UK AB Ellesmere Port CH651AJUK Tayside Contracts Dundee DD38SSUK

Cold mix asphalt manufactured using bitumen emulsion, by its very nature, has struggled to gain market penetration in the UK due to lack of design guidance and specifications and the need to comply with prevailing hot mix asphalt specification requirements. Despite this, a number of contractors have successfully utilized emulsion cold mix asphalt materials containing recycled asphalt planings on various categories of road. Whilst the majority of schemes in the UK have been on lower category traffic roads, in this paper we discuss the use of one material which has been used on a strategic highway(trunk road) in2008 which saved 43 t of CO2 during construction and is still performing well in situ to this day. Site construction details along with an analysis of traffic loading are presented. Laboratory simulations of in-situ curing of material supplied to site demonstrated an indirect tensile stiffness modulus at 10℃ of 5 GPa was achieved within 6 months. Binder recovered from site cores was found to be in line with comparable hot mix materials, whilst wheel tracking of site cores demonstrated excellent deformation resistance which has been borne out by site performance over the last decade. The continued development of standards enabling engineers to design and specify cold mix asphalt in the UK is also reviewed.

关键词： Cold mix Bitumen emulsion Specifications Carbon savings

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Combined extracorporeal shockwave therapy and exercise for the treatment of tendinopathy:A narrative review

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Sports Medicine and Health Science 2022年第1期4卷 8-17页

作者： ian Burton NHS Grampian 172 Market StreetAberdeenAB115PPUnited Kingdom

Tendinopathy is a chronic degenerative musculoskeletal disorder that is common in both athletes and the general *** and extracorporeal shockwave therapy(ESWT)is among the most common treatments used to mediate tendon healing and *** review presents the current understanding of mechanisms of action of ESWT and exercise in isolation and briefly synthesises evidence of their effectiveness for various *** central purpose of the review is to synthesize research findings investigating the combination of ESWT and exercise for five common tendinopathies(plantar heel pain,rotator cuff,lateral elbow,Achilles,and patellar tendinopathy)and provide recommendations on clinical ***,the available evidence indicates that ESWT combined with exercise in the form of eccentric training,tissue-specific stretching,or heavy slow resistance training are effective for specific tendinopathies and can therefore be recommended in *** there are at present a limited number of studies investigating combined EWST and exercise approaches,there is evidence to suggest that the combination improves outcomes in the treatment of plantar heel pain,Achilles,lateral elbow,and rotator cuff ***,despite overall positive outcomes in patellar tendinopathy,the combined treatment has not been shown at present to offer additional benefit over eccentric exercise alone.

关键词： Exercise Muscle stretching exercises High-energy shock waves Tendinopathy Resistance training Extracorporeal shockwave therapy

Lithological and Si–O–S isotope geochemistry:constraints on the origin and genetic environment of the selenium(Se)-rich siliceous rocks in Enshi,Hubei Province,China

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Acta Geochimica 2021年第1期40卷 89-105页

作者： Caixia Feng Shen Liu ian M.Coulson State Key Laboratory of Continental Dynamics and Department of Geology Northwest UniversityXi'an 710069China Solid Earth Studies Laboratory Department of GeologyUniversity of ReginaReginaSK S4S 0A2Canada

Se-rich black rock series of the Middle and Late Permian system is widely distributed in Enshi Prefecture with an exposed area of 850 km~2,among which the unique Yutangba black rock series independent selenium deposit with industrial mining significance in the world is ***,the source and metallogenic mechanisms of Se are still *** general,terrestrial weathering and submarine hydrothermal processes are the main source end members of Si and Se,and the related siliceous rocks record the deposition process of Si and Se from different *** study of lithofacies and paleogeography shows that western Hubei belongs to the near eastwest turn of the Yangzi platform in the Middle and Late Permian and becomes an inter-platform basin with nearly north-south ***,the comparative study of the Yutangba deposit and the selenium-rich black rock series in the northern Shadi with high selenium content is expected to reveal the provenance evolution of the two sections in space,and further restrict the Se mineralization mechanism in the Enshi *** the element geochemistry study,the black rock series in two study areas may have formed in a transitional position of either the continental margin or continental slope,in the process of sedimentary,more terrigenous clastic materials *** are rich in lithophile elements V and Cr.δU>1.0,U/Th and V/(V+Ni)ratio indicate that the Se-rich strata of black rock series in the Enshi areas occurred in an anoxic reducing environment and formed in an environment between the ocean basin and the continental *** Si-O isotope geochemistry,the original Si source of the study area is thought to relate to a volcanic eruption,which leads to the enrichment of Si in the *** determined values of S isotope in the black rock series of the two study areas both show the characteristics related to organic reduction/biogenic.

关键词： Se-rich siliceous rocks Geochemistry Si–O–S isotope Origin Sedimentary environment

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