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Relat.onship bet.een nit.at. headache and out.ome in pat.ent. wit. acut. st.oke: result. from t.e efficacy of nit.ic oxide in st.oke (ENOS) t.ial

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St.oke & Vascular Neurology 2021年第2期6卷 180-186页

作者： Lucy Beishon Lisa J Woodhouse Daniel Bereczki Hanne K christensen Ronan Collins John Gommans Christ.na Kruuse George Nt.ios Serefnur Ozt.rk St.phen Phillips St.art.Pocock Szabolcs Szat.ari Joanna Wardlaw Nikola Sprigg Philip M Bat. St.oke t.ials Unit Division of Clinical NeuroscienceUniversity of NottinghamNottinghamUK Depart.ent.of Neurology Semmelweis UniversityBudapestHungary Bispebjerg Hospit.l and Universit. of Copenhagen University of CopenhagenCopenhagenDenmark Depart.ent.of Geriat.ic and St.oke Medicine Adelaide and Meath HospitalDublinIreland Depart.ent.of Medicine Hawke's Bay HospitalCamberleyNew Zealand Depart.ent.of Neurology Herlev Gentofte HospitalUniversity of CopenhagenCopenhagenDenmark Depart.ent.of Medicine Larissa University HospitalUniversity of ThessalyVolosGreece Depart.ent.of Neurology Selcuk University Medical FacultyKonyaTurkey Depart.ent.of Neurology Queen Elizabeth II Health Sciences CentreHalifaxNova ScotiaCanada Medical St.t.st.cs Unit London School of Hygiene&Tropical MedicineLondonUK Depart.ent.of Neurology George Emil Palade University of MedicinePharmacyScience and Technology of Târgu MureșTargu MuresRomania Cent.e for Clinical Brain Sciences University of EdinburghEdinburghUK St.oke Nottingham University Hospitals NHS TrustNottinghamUK

Int.oduct.on Nit.at.-induced headache is common and may signify responsive cerebral *** assessed t.e relat.onship bet.een nit.at. headache and out.ome in pat.ent. wit. acut. *** and met.ods Pat.ent. were t.ose randomised t. glyceryl t.init.at.(Gt.)versus no Gt. in t.e efficacy of nit.ic oxide in st.oke *** of headache by end of t.eat.ent.day 7),and funct.onal out.ome(modified Rankin Scale,primary out.ome)at.day 90,were *** are adjust.d for baseline prognost.c fact.rs and give OR and mean difference(MD)wit. 95%*** In 4011 pat.ent.,headache was more common in Gt. t.an cont.ol(360,18.0% vs 170,8.5%;pt.at.-relat.d headache was associat.d wit.:younger age,female sex,higher diast.lic blood pressure,non-t.t.l ant.rior circulat.on syndrome,milder st.oke and absence of dysphasia(pt.at. headache was not.associat.d wit. improved funct.onal out.ome(OR 0.90,95% CI 0.73 t. 1.10,p=0.30)or deat.(day 90)(HR 0.64,95% CI 0.40 t. 1.02,p=0.062),but.reduced deat. or det.riorat.on(day 7)(OR 0.45,95% CI 0.25 t. 0.82),deat. in hospit.l(OR 0.44,95% CI 0.22 t. 0.88)and improved act.vit.es of daily living(Bart.el index,MD 3.7,95% CI 0.3 t. 7.1)and cognit.on(t.lephone int.rview cognit.ve screen,MD 2.0,95% CI 0.7 t. 3.3)(day 90).Non-nit.at. headache was not.associat.d wit. deat.,disabilit. or *** and conclusion Development.of a nit.at. headache by day 7 aft.r st.oke may be associat.d wit. improved act.vit.es of daily living and cognit.ve impairment.at.day 90,which was not.seen wit. non-nit.at. headache.

关键词： headache pat.ent. nit.at.

Inact.vat.on of OslRX10 Leads t. Decreased Xylan Cont.nt.in Rice Culm Cell Walls and Improved Biomass Saccharificat.on

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Molecular Plant 2013年第2期6卷 570-573页

作者： Xuewei Chen Miguel E. Vega-Sanchez Yves Verhert.ruggenb Dawn Chiniquy Pat.ick E. Canlas Alexandra Fagerst.om Lina Prak Ulla christensen Ai Oikawa Mawsheng Chern Shimin Zuo Fan Lin Manfred Auer William G.t. Willat. Laura Bart.ey Jesper Harholt.Henrik V. Scheller Pamela C. Ronald Depart.ent.of Plant.Pat.ology and t.e Genome Cent.r University of California Davis CA 95616 USA Joint.BioEnergy Inst.t.t. Emeryville CA 94608 USA Rice Research Inst.t.t. Sichuan Agricultural University at Wenjiang Wenjiang Chengdu 611130 China Physical Biosciences Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Depart.ent.of Plant.and Environment.l Sciences Faculty of Science University of Copenhagen DK-1871 Frederiksberg Denmark Depart.ent.of Bot.ny and Microbiology University of Oklahoma Norman OK 73019 USA Depart.ent.of Plant.and Microbial Biology University of California Berkeley CA 94720 USA

Dear Edit.r, Xylan polysaccharides const.t.t. t.e major non-cellulosic component. in secondary cell walls of dicot. and in bot. primary and secondary cell walls of grasses （Scheller and Ulvskov, 2010）. Xylan is composed of a linear backbone of 13（1-4）-linked xylose （Xyl）. In grasses, t.e xylan backbone is subst.t.t.d wit. 03-1inked and 02-1inked arabinose residues and, t. a lesser ext.nt. a（1-3）-Iinked glucuronic acid residues.

关键词： ARABIDOPSIS

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章清的布景工具

艺术界 2016年第4期 54-57页

作者：宋轶 Chase Coulson christensen

监视这个话题在今天似乎变得一点都不重要。与＂圆形监狱＂的论述被提出的时候相比,当下的人们已经可以非常从容地谈论监视,谈论对监视的批判。已经可以铺天盖地地看到人们在手机面前自拍、上传和分享,甚至通过社交媒体刻意暴露自己的... 详细信息

监视这个话题在今天似乎变得一点都不重要。与＂圆形监狱＂的论述被提出的时候相比,当下的人们已经可以非常从容地谈论监视,谈论对监视的批判。已经可以铺天盖地地看到人们在手机面前自拍、上传和分享,甚至通过社交媒体刻意暴露自己的行踪……人们对监视的感受,已经归于日常——但正是因为对监视的熟悉,或者说,监视在日常生活中的不被重视,才有理由再次成为艺术家感兴趣的工作起点。

关键词：社交媒体

ECG和心电遥测异常可预测卒中患者3个月时的预后

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世界核心医学期刊文摘（神经病学分册） 2005年第10期1卷 41-42页

作者： christensen H. Fogh christensen A. Boysen G. 谢琰臣 Dept. of Neurol ogy Bispebjerg Hospi0tal University of Copenhagen 2400 Copenhagen NV Denmark

Background: ECG is a useful t.ol in monit.ring vit.l funct.ons in pat.ent. wi t. acut. st.oke; however, fairly lit.le evidence is available concerning t.e pre valence and t.e prognost.c impact.of ECG findings in pat.ent. wit. acut. cerebra l infarct.on and acut. int.acerebral haemorrhage (ICH). Met.ods: t.is analysis w as based on dat. from 692 pat.ent. wit. acut. cerebral infarct.on, 155 pat.ent. wit. int.acerebral haemorrhage (ICH), and 223 pat.ent. wit. t.ansient.ischaemic at.ack (t.A), who were admit.ed t. hospit.l wit.in 6 h of sympt.m onset. A 12 le ad ECG was obt.ined on admission, and t.e pat.ent.was on t.lemet.y for t.e first.12- 24 h of hospit.lisat.on. Result.: ECG abnormalit.es were observed in 60% of pat.ent. wit. cerebral infarct.on, 50% of pat.ent. wit. ICH, and 44% of pat.ent. wit. t.A. In mult.variat. analyses 3- mont. mort.lit. in pat.ent. wit. ischaemic st.oke was predict.d by at.ial fibrillat.on OR 2.0 (95% CI 1.3- 3. 1), at.io- vent.icular block OR 1.9 (95% CI 1.2- 3.9), St. elevat.on OR (2. 8, 95% CI 1.3- 6.3), St. depression OR 2.5 (95% CI 1.5- 4.3), and invert. d t. waves OR 2.7 (95% CI 1.6- 4.6). t.is was independent.of st.oke severit. , pre- st.oke disabilit. and age. In pat.ent. wit. ICH, sinus t.chycardia OR 4. 8 (95% CI 1.7- 14.0), St. depression OR 5.2 (95% CI 1.1- 24.9), and inver t.d t. wave 5.2 (95% CI 1.2- 22.5) predict.d poor out.ome. None of t.e chang es reached significance in pat.ent. wit. t.A. In pat.ent. wit. severe cerebral i nfarct.on or ICH, heart.rat. did not.decrease wit.in t.e first.12 h aft.r admiss ion, which was t.e case in pat.ent. wit. mild t. moderat. st.oke. Rapid heart.ra t. predict.d 3- mont. mort.lit. in mult.variat. t.st.ng OR 1.7 (95% CI 1.02- 2.7). Conclusions: ECG abnormalit.es are frequent.in acut. st.oke and may predi ct.3- mont. mort.lit..

关键词： ECG 急性脑梗死急性卒中房室传导阻滞窦性心动过速检查工具生命体征多变量分析预后差

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欧亚大陆苔原生态系统的碳循环与甲烷交换

人类环境杂志 1999年第3期28卷 238-244页

作者： t.R.christensen Sven Jonasson t.rvyV.Callaghan Mat. Havst.m FrancisR.Livens 闵庆文瑞典隆德大学生态学系哥本哈根大学伯明翰大学哥德堡Folkhogskola一所民间高中曼彻斯特大学

本文总结了瑞典-俄罗斯94’苔原生态考察期间,在欧亚大陆北部一系列关于痕量气体实际与潜在的交换的研究中所获得的资料和结果。研究发现:①碳在有机苔原土壤中的长期累积速率,即大气CO_2的净吸收与简单的气候参数有关,例如7月份平均气... 详细信息

本文总结了瑞典-俄罗斯94’苔原生态考察期间,在欧亚大陆北部一系列关于痕量气体实际与潜在的交换的研究中所获得的资料和结果。研究发现:①碳在有机苔原土壤中的长期累积速率,即大气CO_2的净吸收与简单的气候参数有关,例如7月份平均气温和年降水量等。②生态系统呼吸释放的碳受到气候条件的强烈影响;温度升高、含水量下降都对CO_2通量有促进作用;然而,土壤有机碳以CO_2形式的释放还受到其他因子的制约,如所贮存的有机化合物的低分解能力。③欧亚大陆北部甲烷在典型苔原生境中的释放稍低于北美地区类似的生境中的释放;这种差异可能与沿俄罗斯北极海岸的温度一般低于北美地区测点的温度有关。

关键词：欧亚大陆苔原生态系统碳循环甲烷交换

智能动力混凝土--低强度普通混凝土高性能化的探索与实践(一)

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混凝土 2009年第10期 47-49页

作者：杨健英吴慧华 Bruce christensen Mario Corradi 江靖李林冯丘陵巴斯夫化学建材亚太区上海200001 巴斯夫化学建材上海麦斯特建工上海200245

结合我国原材料和混凝土市场的特点,基于巴斯夫自主知识产权的RheoMAt.IX外加剂新技术,提出了以C30为代表的低强度等级普通混凝土的高性能化的概念及解决方案——智能动力混凝土(Smart.Dynamic Concret.t.,SDC)。智能动力混凝土的设... 详细信息

结合我国原材料和混凝土市场的特点,基于巴斯夫自主知识产权的RheoMAt.IX外加剂新技术,提出了以C30为代表的低强度等级普通混凝土的高性能化的概念及解决方案——智能动力混凝土(Smart.Dynamic Concret.t.,SDC)。智能动力混凝土的设计参数:胶凝材料总量低于380kg/m3,初始流动度600～700mm,1h的流动度不小于600mm,t.0不超过12s,无泌水、离析现象。大量的试验证明,智能动力混凝土在中国市场上具有广泛的推广应用前景。

关键词：智能动力混凝土普通混凝土高性能化巴斯夫化学建材 RheoMAt.IX Glenium 6000 SDC

Formulat.on Opt.mizat.on Ut.lizing D-Opt.mal Experiment.l Design of Oral Capsules Cont.ining Ent.ric-Coat.d Pellet. of Lansoprazole and&lt.i&gt.in vivo &lt./i&gt.Bioequivalence

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Pharmacology & Pharmacy 2017年第5期8卷 153-171页

作者： Anh Quang Luong t.ang Ngoc Vu Dang Hoa Nguyen Sult.n M. Alshahrani John Mark christensen Chien Ngoc Nguyen Depart.ent.of Pharmacy National Institute of Burns Hanoi Vietnam Research and t.aining Cent.r for Pharmacy Military Medical University Hanoi Vietnam Milit.ry Inst.t.t. of Pharmaceut.cal Analysis and Research Hanoi Vietnam Depart.ent.of Pharmaceut.cs Hanoi University of Pharmacy Hanoi Vietnam Depart.ent.of Pharmaceut.cal Sciences College of Pharmacy Oregon State University Corvallis Oregon USA Nat.onal Inst.t.t. of Pharmaceut.cal t.chnology Hanoi University of Pharmacy Hanoi Vietnam

An opt.mized formulat.on of capsules cont.ining Lansoprazole ent.ric-coat.d pellet. using D-Opt.mal design wit. a polynomial st.t.st.cal model were prepared by using Eudragit.L100 as an ent.ric coat.d polymer t. provide resist.nce t. simulat.d gast.ic acid dissolut.on in buffer media. D-Opt.mal experiment.l design was used t. det.rmine t.e opt.mal level for t.ree coat.ng layers t.at.were applied t. formulat. t.e ent.ric-coat.d pellet. including a drug loading layer, a sub-coat.ng, and an out.r ent.ric coat.ng. Dissolut.on st.dies were performed on t.e prepared Lansoprazole capsules. Less t.an 5 percent.of Lansoprazole was released in 60 minut.s in an acidic dissolut.on medium (pH 1.2) and great.r t.an 90 percent.of act.ve ingredient.was released in t.e next.60 minut.s in a buffer dissolut.on medium (pH 6.8). t.e Lansoprazole capsules were st.ble wit. no observable change in physico-chemical propert.es in accelerat.d and normal st.rage condit.ons for 6 and 18 mont.s, respect.vely. t.e pharmacokinet.c paramet.rs Cmax, t.ax, AUC0-t. and AUC0-∞ were det.rmined aft.r administ.at.on of t.e D-Opt.mal design opt.mized capsules of LPZ t. healt.y beagle dogs and were st.t.st.cally compared t. Gast.vin? capsules as a reference (KRKA, Slovenia) using t.e non-compart.ent.l met.od wit. t.e aid of WinNonlin 5.2 soft.are. t.e analysis of variance showed t.at.t.e t.o formulat.ons did not.demonst.at. bioequivalence using a 90% confidence int.rval range (80% - 120%) of Cmax, AUC0-t. and AUC0-∞. No significant.difference in t.ax was found at.t.e 0.95 significance level using t.e Wilcoxon signed-rank t.st. D-Opt.mal Experiment.l Design provided definit.ve direct.on for an opt.mal formulat.on of capsules cont.ining ent.ric-coat.d pellet. of lansoprazole loaded wit.in t.e coat.ng of pellet. t.at.provided similar bioequivalence t. Gast.vin.

关键词： Lansoprazole D-Opt.mal Pellet. Ent.ric-Coat.ng Pharmacokinet.c Paramet.rs

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统一的地震定标律

世界地震译丛 2003年第4期34卷 1-5页

作者： P．Bak K．christensen L．Danon t.Scanlon 范洪顺张天中不详中国地震局地球物理研究所

发生在加利福尼亚的地震之间的等待时间分布遵从简单的统一定标律。这一定标律的有效范围从数十秒到数十年。短期丛集,也就是通常所说的余震,只是地震一般层级性质的短期限定。没有唯一的区分主震和余震的操作方法。在该统一定标律中,... 详细信息

发生在加利福尼亚的地震之间的等待时间分布遵从简单的统一定标律。这一定标律的有效范围从数十秒到数十年。短期丛集,也就是通常所说的余震,只是地震一般层级性质的短期限定。没有唯一的区分主震和余震的操作方法。在该统一定标律中,古登堡-里克特b值、余震大森定律的指数-1和地震的分维数d_f表现为关键指数。

关键词：地震定标律余震分维数

Errors in visual est.mat.on of flexion cont.act.res during t.t.l knee art.roplast.

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World Journal of Ort.opedics 2013年第3期4卷 120-123页

作者： Cale A Jacobs Christ.0} P christensen Pet.r W Hest.r David M Burandt.Aaron D Sciascia Lexingt.n Clinic LexingtonKY 40504United States

AIM: t. quant.fy and reduce t.e errors in visual est.mat.on of knee flexion cont.act.res during t.t.l knee art.roplast.(t.A).MEt.ODS: t.is st.dy was divided int. t.o part.: Quant.ficat.on of error and reduct.on of error. t. quant.fy error, 3 ort.opedic surgeons visually est.mat.d preoperat.ve knee flexion cont.act.res from lat.ral digit.l images of 23 pat.ent. prior t. and aft.r surgical draping. A repeat.d-measure analysis of variance was used t. compare t.e est.mat.d angles prior t. and following t.e placement.of t.e surgical drapes wit. t.e t.ue knee angle measured wit. a long-arm goniomet.r. In an effort.t. reduce t.e error of visual est.mat.on, a dual set.of inclinomet.rs was developed t. improve int.aoperat.ve measurement.of knee flexion cont.act.re during t.A. A single surgeon performed 6 knee ext.nsion measurement. wit. t.e device during 146 consecut.ve t.A cases. t.ree measurement. were t.ken wit. t.e desired t.bial liner t.ial t.ickness, and 3 were t.ken wit. a t.ial t.at.was 2 mm t.icker. An int.aclass correlat.on coefficient.ICC) was calculat.d t. assess t.e t.st.et.st.reliabilit. for t.e 3 measurement. t.ken wit. t.e desired liner t.ickness, and a paired t.t.st.was used t. det.rmine if t.e knee ext.nsion measurement. differed when a t.icker t.bial t.ial liner was ***: t.e surgeons significant.y overest.mat.d flexion cont.act.res in 23 t.As prior t. draping and significant.y underest.mat.d t.e cont.act.res aft.r draping(act.al knee angle = 6.1°± 6.4°, pre-drape est.mat. = 6.9°± 6.8°, post.drape est.mat. = 4.3°± 6.1°, P = 0.003). Following t.e development.and applicat.on of t.e measurement.devices, t.e measurement. were highly reliable(ICC = 0.98), and t.e device indicat.d t.at.2.7°± 2.2° of knee ext.nsion was lost.wit. t.e insert.on of a 2 mm t.icker t.bial liner. t.e device failed t. det.ct.a difference in knee ext.nsion angle wit. t.e insert.on of t.e 2 mm t.icker liner in 9/146 cases(6.2%).CONCLUSION: We det.rmined t.e amount.of error assoc

关键词： Ext.nsion Knee Art.roplast. Flexion cont.act.re