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Towar. a nomenclatur. consensus for.diver.e intelligent systems:Call for.collabor.tion

The Innovation 2024年第5期5卷 32-34页

作者： Br.tt J.Kagan Michael Mahlis Anjali Bhat Josh Bongar. Victor.MCole Phillip Cor.ett Chr.stopher.Gyngell Thomas Har.ung Bianca Jupp Michael Levin Tamr. Lysaght Nicholas Opie Adeel r.zi Lena Smir.ova ian Tennant Peter.Thestr.p Wade Ge Wang Cor.ical Labs BrunswickVIC 3056Australia Wellcome Centr. for.Human Neur.imaging University College LondonLondon WC1N 3ARUK Univer.ity of Ver.ont BurlingtonVT 05405USA Centr. for.Pr.fessional Communication Singapore Institute of TechnologySingapore 138683Singapore Depar.ment of Psychiatr. Yale UniversityNew HavenCT 06511USA Mur.och Childr.n’s r.sear.h Institute ParkvilleVIC 3052Australia Centr. for.Alter.atives to Animal Testing(CAAT) Bloomberg School of Public Health and Whiting School of EngineeringJohns Hopkins UniversityDoerenkamp-Zbinden Chair for Evidence-based ToxicologyBaltimoreMD 21205USA CAAT-Eur.pe University of Kostanz78464 KostanzGermany Depar.ment of Neur.science Central Clinical SchoolMonash UniversityPrahranVIC 3004Australia Allen Discover. Centr. at Tufts Univer.ity MedfordMA 02155USA Yong Loo Lin School of Medicine National University of SingaporeSingapore 117597Singapore Faculty of Medicine and Health Sydney School of Public Health The University of SydneyCamperdownNSW 2050Australia Depar.ment of Medicine University of MelbourneParkvilleVIC 3010Australia Tur.er.Institute for.Br.in and Mental Health Monash UniversityClaytonVIC 3168Australia Center.for.Alter.atives to Animal Testing(CAAT) Bloomberg School of Public Health and Whiting School of EngineeringJohns Hopkins UniversityBaltimoreMD 21205USA Faculty of Engineer.ng AgriTech and EnvironmentAnglia Ruskin UniversityPeterborough PE15BWUK Inter.cting Minds Centr. Aarhus University8000 Aarhus CDenmark Depar.ment of Biomedical Engineer.ng School of EngineeringBiomedical Imaging CenterCenter for Biotechnology and Interdisciplinary StudiesRensselaer Polytechnic InstituteTroyNY 12180USA Depar.ment of Biochemistr. and Phar.acology University of MelbourneParkvilleVIC 3010Australia

Disagr.ements about language use ar. common both between and within *** inter.sts r.quir. multidisciplinar. collabor.tion or.the field of r.sear.h has the potential to impact society at lar.e,it becomes cr.tical to minimize these disagr.ements wher. *** development of diver.e intelligent systems,r.gar.less of the substr.te(e.g.,silicon ***),is a case wher. both conditions ar. *** advancements have occur.ed in the development of technology pr.gr.ssing towar. these diver.e intelligence *** pr.gr.ss is silicon based,such as the use of lar.e language models,or.thr.ugh synthetic biology methods,such as the development of or.anoids,a clear.need for.a community-based appr.ach to seeking consensus on nomenclatur. is now ***,we welcome collabor.tion fr.m the wider.scientific community,pr.posing a pathway for.ar. to achieving this intention,highlighting key ter.s and fields of r.levance,and suggesting potential consensus-making methods to be applied.

关键词： seeking collabor.tion diver.e

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Effects of symmetr.c and asymmetr.c salt conditions on a selective solid-state nanopor. assay

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Nano r.sear.h 2022年第11期15卷 9936-9942页

作者： ian D.Wadswor.h Adam r.Hall Vir.inia Tech-Wake For.st Univer.ity School of Biomedical Engineer.ng and Sciences Wake Forest School of MedicineWinston-SalemNC 27101USA Compr.hensive Cancer.Center Wake Forest School of MedicineWinston-SalemNC 27157USA

Conventional solid-state nanopor. measur.ments sense all tr.nslocating entities,necessitating meticulous analysis to differ.ntiate tar.et *** addr.ss this,we have established a selective assay with the platfor. that has shown utility in quantifying sever.l nucleic acid ***,limited detection efficiency and intr.nsic noise have so far.limited assay r.solution to 10 *** in this value r.quir. manipulation of tr.nslocation ***,we r.por. the effects of NaCl conditions on assay *** fir.t investigate symmetr.c conditions,finding sensitivity incr.ases with salt concentr.tion but selectivity is maximized at 1.0 M *** then pr.be asymmetr.c conditions,showing a r.mar.able impact on assay sensitivity and selectivity when measur.ment buffer.NaCl concentr.tion in the r.ser.oir.with the tr.nslocating molecules is low and the opposite r.ser.oir.is *** optimum conditions,we demonstr.te detection of tar.et biomolecules down to a concentr.tion of 100 pM which is an impr.vement of 2 or.er. of magnitude over.past r.sults.

关键词： solid-state nanopor.s biomar.er. amplification-fr.e detection salt gr.dient nucleic acids

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Per.odic Addition of Glucose Suppr.ssed Cyanobacter.al Abundance in Additive Lake Water.Samples dur.ng the Entir. Bloom Season

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Jour.al of Water.r.sour.e and Pr.tection 2024年第2期16卷 140-155页

作者： David Linz ian Str.ewing Nathan Sienkiewicz Alan David Steinman Char.yn Gwen Par.r.dge Kyle McIntosh Joel Allen Jingr.ng Lu Stephen Vesper United States Envir.nmental Pr.tection Agency Cincinnati Ohio USA Annis Water.r.sour.es Institute Grand Valley State University Muskegon USA Oak r.dge Institute for.Science and Education Oak Ridge Tennessee USA

Pr.viously, we showed that pr.phylactic addition of glucose to Har.ha Lake water.samples could inhibit cyanobacter.a gr.wth, at least for.a shor. per.od of time. The cur.ent study tested cyanobacter.al contr.l with glucose for.the entir. Har.ha Lake bloom season. Water.samples (1000 ml) wer. collected weekly fr.m Har.ha Lake dur.ng the algal-bloom season star.ing June 9 and lasting until August 24, 2022. To each of two 7-liter.polypr.pylene container., 500 ml of Har.ha Lake water.was added, and the container. wer. placed in a contr.lled envir.nment chamber. To one container.labeled “Tr.ated,” 0.15 g of glucose was added, and nothing was added to the container.labeled “Contr.l.” After.that, thr.e 25 ml samples fr.m each container.wer. collected and used for.16S r.NA gene sequencing each week. Then 1000 ml of Har.ha Lake water.was newly collected each week, with 500 ml added to each container. along with the addition of 0.15 g glucose to the “Tr.ated” container. Sequencing data wer. used to examine differ.nces in the composition of bacter.al communities between Tr.ated and Contr.l container.. Tr.atment with glucose alter.d the micr.bial communities by 1) r.ducing taxonomic diver.ity, 2) lar.ely eliminating cyanobacter.al taxa, and 3) incr.asing the r.lative abundance of subsets of non-cyanobacter.al taxa (such as Pr.teobacter.a and Actinobacter.ota). These effects wer. obser.ed acr.ss time despite weekly inputs der.ved dir.ctly fr.m Lake water. The addition of glucose to a container.r.ceiving weekly additions of Lake water.suppr.ssed the cyanobacter.al populations dur.ng the entir. summer.bloom season. The glucose appear. to stimulate the diver.ity of cer.ain bacter.al taxa at the expense of the cyanobacter.a.

关键词： Glucose Cyanobacter.a 16S Amplicon Sequencing Micr.bial Community

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Death r.lated to ethyl chlor.de inhalation abuse: a case r.por.

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Wor.d Jour.al of Emer.ency Medicine 2022年第5期13卷 422-424页

作者： ian Zhir.i Hong r.Ponampalam Depar.ment of Emer.ency Medicine Singapore General Hospital169608Singapore

Dear.editor.Human exposur. to hydr.car.ons(HCs)is unavoidable given their.wide usage in a var.ety of common *** chlor.de(EC),a type of halogenated HC,has been used in the pr.duction of phar.aceuticals,dyes,and other.chemicals used for.industr.al pur.oses.[1,2]EC was used as an anesthetic induction agent in the ear.y 1900s.[3]Although its use as an inhalational agent has fallen out of favour.EC is still used as a topical pain medication today.[4]

关键词： hydr.car.ons agent editor

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冰火两重天纽约Other.hip洗浴中心

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室内设计与装修 2024年第9期 8-11页

作者： [美国]Futur.studio 秋落(编译) ian Patter.on(摄影) Futur.studio

Other.hip是一种社交桑拿和冰浴体验,客人在此仿佛进入另一个世界。Other.hip提供有指导的课程、自由流动和社交活动,将呼吸法、肢体运动和现场音乐融为一体,创造了一个能让人快乐地拥抱情绪和脆弱心理的环境,让人们善待自己,拥有健康... 详细信息

Other.hip是一种社交桑拿和冰浴体验,客人在此仿佛进入另一个世界。Other.hip提供有指导的课程、自由流动和社交活动,将呼吸法、肢体运动和现场音乐融为一体,创造了一个能让人快乐地拥抱情绪和脆弱心理的环境,让人们善待自己,拥有健康的心态,并建立社区。

关键词：洗浴中心社交活动肢体运动健康的心态自由流动呼吸法善待自己

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微软开发冷却技术让芯片“泡澡”

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商业周刊（中文版） 2024年第4期 18-19页

作者： ian King Dina Bass 融汐(译) 不详

●数据中心越来越重视用液体而非空气来冷却服务器组件以纳米为单位计量的半导体是现代人工智能数据中心里的奇异之物,但在这些设施中,称得上最重要机器的还有风扇。如果没有不断吹过一排排计算机的冷空气,先进的芯片能将自己烧毁。但是... 详细信息

●数据中心越来越重视用液体而非空气来冷却服务器组件以纳米为单位计量的半导体是现代人工智能数据中心里的奇异之物,但在这些设施中,称得上最重要机器的还有风扇。如果没有不断吹过一排排计算机的冷空气,先进的芯片能将自己烧毁。但是,运行足够多的风扇和空调以防止这种情况发生的成本太高,这促使芯片制造商和数据中心运营商不断寻找完全不同的方法来解决问题。

关键词：数据中心服务器组件芯片制造商冷却技术半导体计算机微软风扇

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Autoimmune liver.diseases

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Wor.d Jour.al of Gastr.enter.logy 2008年第21期14卷 3290-3291页

作者： Pietr. Inver.izzi ian r.Mackay Division of Inter.al Medicine and Liver.Unit San Paolo Hospital School of MedicineUniversity of MilanMilan 20142ItalyDivision of RheumatologyAllergyand Clinical ImmunologyUniversity of California at DavisDavisCAUnite States Depar.ment of Biochemistr. & Molecular.Biology Monash UniversityClaytonVictoria 3800Australia

The liver.was one of the ear.iest r.cognized sites among autoimmune diseases yet autoimmune hepatitis,pr.mar. biliar. cir.hosis,pr.mar. scler.sing cholangitis,and their.over.ap for.s,ar. still pr.blematic in diagnosis and *** contr.butions her.in compr.se 'pair. of ar.icles' on clinical char.cter.stics,and concepts of etiopathogenesis,for.each of the above diseases,together.with childhood autoimmune liver.disease,over.aps,inter.r.tations of diagnostic ser.logy,and liver.*** issue is timely,since we ar. witnessing an ever.incr.asing applicability of immunology to a wide var.ety of chr.nic diseases,hepatic and non-hepatic,in both developed and developing *** 11 invited exper. r.view ar.icles captur. the changing featur.s over.r.cent year. of the autoimmune liver.diseases,the under.ying immunomolecular.mechanisms of development,the potent albeit still unexplained genetic influences,the expanding r.per.oir. of immunoser.logical diagnostic mar.er.,and the incr.asingly effective ther.peutic possibilities.

关键词： Autoimmunity Autoimmune liver.diseases Immunopathogenic pr.cessess Clinical immunology

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技术交易网络与出口企业成本加成——基于中国专利转让与许可的经验研究

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中国工业经济 2024年第4期 76-94页

作者：许和连王伦邓玉萍湖南大学经济与贸易学院

基于中国专利转让与许可数据,本文运用复杂网络方法构建技术交易网络,科学评估了企业在技术交易网络的位置,据此考察出口企业嵌入技术交易网络对其成本加成的影响。研究发现,出口企业在技术交易网络中的中心性位置显著影响其成本加成,... 详细信息

基于中国专利转让与许可数据,本文运用复杂网络方法构建技术交易网络,科学评估了企业在技术交易网络的位置,据此考察出口企业嵌入技术交易网络对其成本加成的影响。研究发现,出口企业在技术交易网络中的中心性位置显著影响其成本加成,且这一促进作用是通过缓解信息不对称性、提高企业自主创新与协同创新能力来实现。异质性检验表明,企业处于输出地位、企一企型技术交易网络带来的成本加成提升作用更为显著;技术交易网络对西部地区、技术密集型行业、国有性质、从事加工贸易的出口企业成本加成提升相对更大。另外,技术交易的服务保障体系建设至关重要,知识产权司法保护的推进、技术交易中介的建立及其功能完善均会强化技术交易网络下的出口企业优势,尤其是国家技术转移示范机构、“中国创新驿站”的试点政策导致技术交易的成本加成提升作用从距离转移服务机构20千米扩大到40千米范围内。本文研究为畅通企业等多主体间技术要素流动、促进科技创新与贸易竞争新优势相结合提供了微观证据。

关键词：技术市场专利交易成本加成复杂网络

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Accur.te pr.diction of myopic pr.gr.ssion and high myopia by machine lear.ing

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Pr.cision Clinical Medicine 2024年第1期7卷 14-20页

作者： Jiahui Li Simiao Zeng Zhihuan Li Jie Xu Zhuo Sun Jing Zhao Meiyan Li Zixing Zou Taihua Guan Jin Zeng Zhuang Liu Wenchao Xiao r.n Wei Hanpei Miao ian Ziyar.Junxiong Huang Yuanxu Gao Yangfa Zeng Xing-Tao Zhou Kang Zhang Guangzhou Women and Childr.n's Medical Center Guangzhou Medical UniversityGuangzhou 510120China Guangzhou National Labor.tor. Guangzhou 510o0oChina Zhuhai Inter.ational Eye Center.of the Fir.t Affiliated Hospital of Faculty of Medicine Macao University of Science and TechnologyZhuhai 519000China Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing 100069China Key Labor.tor. of Myopia Ministry of HealthShanghai Key Laboratory of Visual Impairment and RestorationDepartment of OphthalmologyEye InstituteEye and EarNoseand Throat HospitalFudan UniversityShanghai 200031China DongguanPeople's Hospital The First School of Clinical MedicinelSouthern Medical UniversityDongguan 523059China State Key Labor.tor. of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060China Wenzhou Eye Hospital and Institute for.Advanced Study on Eye Health and Diseases Wenzhou Medical UniversityWenzhou 32500oChina

Backgr.und Myopia is a leading cause of visual impair.ent in Asia and ***,accur.tely pr.dicting the pr.gr.ssion of myopia and the high r.sk of myopia r.mains a *** study aims to develop a pr.dictive model for.the development of *** We fir.t r.tr.spectively gather.d 612530 medical r.cor.s fr.m five independent cohor.s,encompassing 227543 patients r.nging fr.m infants to young ***,we developed a multivar.ate linear.r.gr.ssion algor.thm model to pr.dict the pr.gr.ssion of myopia and the r.sk of high *** The model to pr.dict the pr.gr.ssion of myopia achieved an r.(2) value of 0.964 vs a mean absolute er.or.MAE)of 0.119D[95%confidence inter.al(CI):0.119,1.146]in the inter.al validation *** demonstr.ted str.ng gener.lizability,maintaining consistent per.or.ance acr.ss exter.al validation sets:r.(2)=0.950 vs MAE=0.119D(95%CI:0.119,1.136)in validation study 1,r.(2)=0.950 vs MAE=0.121D(95%CI:0.121,1.144)in validation study 2,and r.(2)=0.806 vs MAE=−0.066D(95%CI:−0.066,0.569)in the Shanghai Childr.n Myopia *** the Beijing Childr.n Eye Study,the model achieved an r.(2) of 0.749 vs a MAE of 0.178D(95%CI:0.178,1.557).The model to pr.dict the r.sk of high myopia achieved an ar.a under.the cur.e(AUC)of 0.99 in the inter.al validation set and consistently high ar.a under.the cur.e values of 0.99,0.99,0.96 and 0.99 in the r.spective exter.al validation *** Our.study demonstr.tes accur.te pr.diction of myopia pr.gr.ssion and r.sk of high myopia pr.viding valuable insights for.tailor.ng str.tegies to per.onalize and optimize the clinical management of myopia in childr.n.

关键词： myopia pr.gr.ssion machine lear.ing pr.vention pr.cision medicine

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英特尔复兴计划

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商业周刊（中文版） 2024年第7期 38-45页

作者： MAX CHAFKIN ian KING KELDA VAN PATTEN(摄影/插图) 杨飞(译) 不详

几个月前,一艘拖船从新奥尔良出发,推着一艘驳船沿密西西比河逆流而上。它向北穿过南方腹地,然后向东航行,经过印第安纳州俄亥俄河沿岸的农田。驳船上装载着一个用于巨型空气分离装置的冷箱,这是一种从大气中提取氮气用于制造的工业设... 详细信息

几个月前,一艘拖船从新奥尔良出发,推着一艘驳船沿密西西比河逆流而上。它向北穿过南方腹地,然后向东航行,经过印第安纳州俄亥俄河沿岸的农田。驳船上装载着一个用于巨型空气分离装置的冷箱,这是一种从大气中提取氮气用于制造的工业设备。这件货物的体积实在太大了,如果在辛辛那提转运,集装箱船通常要在俄亥俄州南部卸货,这种做法不切实际。

关键词：印第安纳州空气分离装置集装箱船密西西比河新奥尔良复兴计划俄亥俄河俄亥俄州

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