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DWi预测治疗前乳腺癌病人对新辅助化疗的反应性

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国际医学放射学杂志 2013年第6期 593-594页

作者： R.Richard i.thomassin M.Chapellier A.Scemama P.de Cremoux M.Varna 时代刘倩 Radiology Department Saint-Louis Hospital1 avenue Claude Vellefaux75010 Paris France

摘要目的评估表观扩散系数(ADC)值对不同类型乳腺癌病人采用新辅助化疗后反应性的预测能力。材料与方法该回顾性研究已得到相应机构委员会的批准。研究人群为

关键词：乳腺癌扩散磁共振成像新辅助化疗预后肿瘤的组织学类型

自动主成分分析滤过改进动态对比增强CT与MRi的信噪比

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国际医学放射学杂志 2011年第2期 179-180页

作者： D.Balvay N.Kachenoura S.Espinoza i.thomassin-Naggara L.S.Fournier O.Clement 唐光健 iNSERM U970 Paris Cardiovascular Research Center(PARCC)

目的开发一种新的自动主成分滤过技术并评价其对动态对比增强(DCE)MR与CT数据中已知低信噪比(CNR)代偿,而无明显信号损失的能力。材料与方法研究中

关键词：动态对比增强 MRi 主成分分析多元分析滤过 CT

子宫内膜癌MRi分期:欧洲泌尿生殖放射学会最新指南

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国际医学放射学杂志 2019年第2期42卷 253-253页

作者： S.Nougaret M.Horta E.Sala Y.Lakhman i.thomassin-Naggara A.Kido 杨凯(译) 赵世华(校) iRCM Montpellier Cancer Research institute208 Ave des Apothicaires34295 MontpellierFrance 不详

目的对2009欧洲泌尿生殖放射学会(ESUR)子宫内膜癌指南进行更新,并提出子宫内膜癌MRi分期规范化影像采集、解读及报告的策略。方法采用RAND-UCLA合理性方法(RAM)对已发表的基于证据的数据和专家意见进行结合,作为这些共识指南的基础。

关键词：子宫内膜癌放射学会泌尿生殖 MRi

磁共振扩散加权成像在复杂附件肿块良性预测方面的作用

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国际医学放射学杂志 2009年第4期32卷 416-416页

作者： i.thomassin-Naggara E.Dara C.A. Cuenod L.Fournier i.Toussaint C.Marsault 刘学焕 Department of Radiology Höpital Tenon Assistance Publique Hopitaux de Paris

本研究的目的为前瞻性评价MR扩散加权成像在区分复杂附件肿块中的作用。77例（22～87岁）复杂性附件肿块病人（30例良性,47例恶性）均于术前行包括扩散加权成像的MRi检查。除分析常规MRi表现外,还测量了b值为1000的囊性及实性部分的表... 详细信息

本研究的目的为前瞻性评价MR扩散加权成像在区分复杂附件肿块中的作用。77例（22～87岁）复杂性附件肿块病人（30例良性,47例恶性）均于术前行包括扩散加权成像的MRi检查。除分析常规MRi表现外,还测量了b值为1000的囊性及实性部分的表观扩散系数（ADC）值。计算预测良恶性病变的阳性似然比（PRL）。预测良性最有意义的标准为实性部分在b值为1000条件下呈低信号（PRL=10．9）,T2低信号（PRL=5．7）,无实性成分（PRL=3．1）,无腹水或腹膜种植（PRL=2-3）和无乳头状突起（PRL=2．3）。

关键词： MRi 扩散卵巢肿物特征

复杂附件肿块的特征:传统MRi联合MR灌注和扩散加权成像的价值

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国际医学放射学杂志 2011年第3期 278-278页

作者： i.thomassin-Naggara i.Toussaint N.Perrot R.Rouzier C.A.Cuenod M.Bazot 孙海涛 Department of Radiology HOipital TenonUniversité Pierre et Marie Curie4 rue de la Chine75020 ParisFrance

目的回顾性评价传统MR联合MR灌注(PW)和扩散加权(DW)成像鉴别良恶性病变的价值。材料与方法本回顾性研究获机构伦理委员会同意并免签知情同意书。87

关键词： MRi PWi 常规 MR DWi

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MRi鉴别子宫肌层良性与恶性肿瘤

国际医学放射学杂志 2013年第5期 509-509页

作者： i.thomassin-Naggara S.Dechoux C.Bonneau A.Morel R.Rouzier M.F.Carette 余太慧 Service de Radiologie Hpital Tenon

摘要目的回顾性评价MRi鉴别子宫肌层良性与恶性肿瘤的能力。方法 51例女性在手术前行MRi检查以评价子宫肌层单发的肿瘤。组织病理学证实其中25例为不确定或恶性间质性肿瘤,26例为良性平滑肌瘤。除常规MRi形态学标准以外还记录b1 000信... 详细信息

摘要目的回顾性评价MRi鉴别子宫肌层良性与恶性肿瘤的能力。方法 51例女性在手术前行MRi检查以评价子宫肌层单发的肿瘤。组织病理学证实其中25例为不确定或恶性间质性肿瘤,26例为良性平滑肌瘤。除常规MRi形态学标准以外还记录b1 000信号强度及其表观扩散系数(ADC)。并将各数据转化为优势比(OR)作为统一标准。一个多变量分析,构建成一个解释模型。结果提示子宫恶性肿瘤的标准是b1 000信号呈高强度(OR=+∞),T2Wi呈等信号(OR=+∞),

关键词：子宫肌层常规 ADC 恶性肿瘤平滑肌瘤平滑肌肿瘤肌肉组织肿瘤 MRi

Audiological results of endoscopic surgical repair of the long process of incus

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2017年第3期3卷 148-152页

作者： Badi Aldosari Jean-Marc thomassin Department of Otolaryngology-Head and Neck Surgery King Saud UniversityRiyadhSaudi Arabia Department of Otolaryngology-Head and Neck Surgery La Timone University HospitalAix-Marseille UniversityMarseilleFrance

Objective:The purpose of this study is to evaluate our experience with endoscopic repair of ossicular discontinuity at the incudostapedial joint,with or without an intact stapes suprastructure,and present our hearing *** classify results based on the causative pathology,the type of ossiculoplasty,and type of *** demonstrate the ability to endoscopically place a total ossicular replacement prosthesis (TORP),measuring 4.25 mm,between the stapes footplate and the incus remnant to reestablish ossicular ***:This was a retrospective case series conducted in tertiary referral center (Hopital de la Timone) Marseille,France.25 patients underwent incudostapedial rebridging ossiculoplasty between 2009 and *** cases of chronic otitis media and 10 otosclerosis revisions were included in the *** different materials were used in ossiculoplasty,hydroxyapatite cement,incus remnant,and partial/total ossicular replacement *** results were evaluated before and after *** month follow-up data is ***:The mean postoperative air-bone gap was 15 dB (5-25 dB).Hearing results were better inotosclerosis *** cement produced an air-bone gap of 5 dB,TORP placed under the incus produced a 12 dB gap,and TORP placed under the malleus resulted in a 12 dB gap and one deaf *** cases of chronic otitis media,the residual air-bone gap was 17 dB with PORP,12 dB with TORP,and 20 dB with incus ***:The hydroxyapatite cement is effective in the reconstruction of ossicular discontinuity but the high price limits its *** placed under the incus is a reliable and stable method of ossicular reconstruction that is cost effective and offers satisfactory hearing results in selected patients.

关键词： Endoscopic ear surgery Ossiculoplasty incus Ossiculoplasty outcomes

Magnetic resonance imaging may predict deep remission in patients with perianal fistulizing Crohn's disease

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World Journal of Gastroenterology 2017年第23期23卷 4285-4292页

作者： Lucie thomassin Laura Armengol-Debeir Cloé Charpentier Valerie Bridoux Edith Koning Guillaume Savoye Céline Savoye-Collet Department of Gastroenterology Rouen University HospitalUniversity of Rouen Department of Radiology Rouen University HospitalUniversity of Rouen Department of Digestive Surgery Rouen University HospitalUniversity of Rouen

AiM To evaluate the imaging course of Crohn's disease(CD) patients with perianal fistulas on long-term maintenance anti-tumor necrosis factor(TNF)-α therapy and identify predictors of deep *** All patients with perianal CD treated with anti-TNF-α therapy at our tertiary care center were evaluated by magnetic resonance imaging(MRi) and clinical assessment. Two MR examinations were performed: at initiation of anti-TNF-α treatment and then at least 2 years after. Clinical assessment(remission, response and non-response) was based on Present's criteria. Rectoscopic patterns, MRi Van Assche score, and MRi fistula activity signs(T2 signal and contrast enhancement) were collected for the two MR examinations. Fistula healing was defined as the absence of T2 hyperintensity and contrast enhancement on MRi. Deep remission was defined as the association of both clinical remission, absence of anal canal ulcers and healing on MRi. Characteristics and imaging patterns of patients with and without deep remission were compared by univariate and multivariate *** Forty-nine consecutive patients(31 females and 18 males) were included. They ranged in age from 14-70 years(mean, 33 years). MRi and clinical assessment were performed after a mean period of exposure to anti-TNF-α therapy of 40 ± 3.7 mo. Clinical remission, response and non-response were observed in 53.1%, 20.4%, and 26.5% of patients, respectively. Deep remission was observed in 32.7% of patients. Among the 26 patients in clinical remission, 10 had persisting inflammation of fistulas on MRi(T2 hyperintensity, n = 7; contrast enhancement, n = 10). Univariate analysis showed that deep remission was associated with the absence of rectal involvement and the absence of switch of anti-TNF-α treatment or surgery requirement. Multivariate analysis demonstrated that only the absence of rectal involvement(OR = 4.6; 95%Ci: 1.03-20.5) was associated with deep *** Deep remission is achieved in

关键词： Crohns 疾病肛门管磁性的回声成像肛门疾病 / 诊断 Biotherapy

子宫栓塞治疗黏膜下纤维瘤:一种不好的替代外科手术的治疗方法?(法)

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世界核心医学期刊文摘（妇产科学分册） 2006年第6期2卷 43-44页

作者： Fiori O. thomassin-Naggara i. Bazot M. 李欢 Service de Gynécologie-obstétrique et Médecine de la Reproduction Hpital TenonAP- HP 4 rue de laChine75020 Paris France

A case of septic expulsion of a leiomyoma is reported 18 weeks after uterine artery embolisation (UAE). The patient underwent UAE for a symptomatic sub- mucous leiomyoma (type 2) of 5 cm. She was feverish and presented pelvic pain and purulent vaginal discharges. Vaginal examination revealed a necrotic mass prolapsed through the cervix that was carefully twisted out. Histopathologic examination showed extensive necrosis of the myomatous tissue. Microbiologic cultures showed heavy growth of Escherichia coli. Such findings challenge the interest and the safety of UAE for submucous fibroids. Our case report stresses that uterine artery embolisation for submucous fibroids does not constitute, because of its risks, an alternative to conventional surgical treatment represented mainly by hysteroscopic resection.

关键词：子宫动脉栓塞术黏膜下纤维瘤治疗方法外科手术栓塞治疗病理组织学检查 UAE治疗平滑肌瘤阴道分泌物