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Mi.roRNAs as potenti.l di.gnosti. bi.markers for bi.olar di.order

Neural Regenerati.n Research 2025年第6期20卷 1681-1695页

作者： Bri.get Marti.ez Phi.i. v.Peplow Department of Pharmacology University of Nevada-RenoRenoNVUSA Department of Medi.i.e University of Nevada-RenoRenoNVUSA Department of Anatomy University of OtagoDunedinNew Zealand

Abnormal expressi.n of mi.roRNAs i. connected to brai. dev.lopment and di.ease and could prov.0}e nov.l bi.markers for the di.gnosi. and prognosi. of bi.olar di.order. We performed a PubMed search for mi.roRNA bi.markers i. bi.olar di.order and found 18 ori.i.al research arti.les on studi.s performed wi.h human pati.nts and publi.hed from January 2011 to June 2023. These studi.s i.cluded mi.roRNA profi.i.g i. bloodand brai.-based materi.ls. From the studi.s that had v.li.ated the preli.i.ary fi.di.gs,potenti.l candi.ate bi.markers for bi.olar di.order i. adults could be mi.-140-3p,-30d-5p,-330-5p,-378a-5p,-21-3p,-330-3p,-345-5p i. whole blood, mi.-19b-3p,-1180-3p,-125a-5p, let-7e-5p i. blood plasma, and mi.-7-5p,-23b-5p,-142-3p,-221-5p,-370-3p i. the blood serum. Two of the studi.s had i.v.sti.ated the changes i. mi.roRNA expressi.n of pati.nts wi.h bi.olar di.order recei.i.g treatment. One showed a si.ni.i.ant i.crease i. plasma mi.-134 compared to baseli.e after 4 weeks of treatment whi.h i.cluded typi.al anti.sychoti.s, atypi.al anti.sychoti.s, and benzodi.zepi.es. The other study had assessed the effects of prescri.ed medi.ati.ns whi.h i.cluded neurotransmi.ter receptorsi.e bi.ders(drug class B) and sedati.es, hypnoti.s, anti.onv.lsants, and analgesi.s(drug class C) on mi.roRNA results. The combi.ed effects of the two drug classes i.creased the si.ni.i.ance of the results for mi.-219 and-29c wi.h mi.-30e-3p and-526b* acqui.i.g si.ni.i.ance. Mi.roRNAs were tested to see i. they could serv. as bi.markers of bi.olar di.order at di.ferent cli.i.al states of mani., depressi.n, and euthymi.. One study showed that upregulati.n i. whole blood of mi.-9-5p,-29a-3p,-106a-5p,-106b-5p,-107,-125a-3p,-125b-5p and of mi.-107,-125a-3p occurred i. mani. and euthymi. pati.nts compared to controls, respecti.ely, and that upregulati.n of mi.-106a-5p,-107 was found for mani. compared to euthymi. pati.nts. i. two other studi.s usi.g blood plasma,downregulati.n of mi.-134 was observ.d i

关键词： bi.marker bi.olar di.order blood leukocytes blood plasma blood plasma extracellular v.si.les/exosomes blood serum brai. ti.sue brai. ti.sue extracellular v.si.les/exosomes lymphoblastoi. cell li.es mi.roRNA neural progeni.or cells whole blood

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Prov.nance of Precambri.n Fe- and Al-ri.h Metapeli.es i. the Yeni.ey Ri.ge and Kuznetsk Alatau, Si.eri.: Geochemi.al Si.natures

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Acta Geologi.a Si.i.a(Engli.h Edi.i.n) 2007年第3期81卷 409-423页

作者： i.or i. li.hanov.v.adi.i. v. rev.rdatto i.sti.ute of Geology and Mi.eralogy Si.eri.n Branch Russian Academy of SciencesPr. Acad. Koptyuga3Novosibirsk630090Russian Federation

Major, trace and rare earth element contents of Fe- and Al-ri.h metapeli.es from the Korda （Yeni.ey Ri.ge） and Amar （Kuznetsk Alatau） formati.ns were determi.ed to exami.e the nature, ori.i. and ev.luti.n of thei. protoli.hs. Results i.di.ate that these rocks are the redeposi.ed and metamorphosed products of Precambri.n kaoli.i.i. weatheri.g crusts, whi.e the geochemi.al di.ti.cti.ns between the studi.d metapeli.es are determi.ed by di.ferent weatheri.g condi.i.ns i. the source area and tectoni. setti.gs. The protoli.h of the Korda Formati.n metapeli.es was produced by erosi.n products of the post-Archean grani.oi. rocks, whi.h accumulated under humi. cli.ate condi.i.ns i. shallow-water basi.s along the conti.ental margi.. The geochemi.al characteri.ti.s of the deeper pri.ary deposi.s of the Amar Formati.n suggest that v.lcanogeni. materi.l of mafi. composi.i.n deri.ed from an i.land-arc env.0}onment had a major role i. supplyi.g the erosi.n zone. These results agree wi.h li.hofaci.s data and wi.h the geodynami. reconstructi.n of the ev.luti.n of the Yeni.ey Ri.ge and Kuznetsk Alatau duri.g the Mesoproterozoi. and Neoproterozoi., respecti.ely. i. was shown that REEs had li.i.ed mobi.i.y duri.g contact metamorphi.m. The coherent mobi.i.y of REEs duri.g colli.i.nal metamorphi.m may be attri.uted both to mi.eral reacti.ns responsi.le for modal changes and to local chemi.al heterogenei.y i.heri.ed from the i.i.i.l protoli.h.

关键词： geochemi.try protoli.h peli.i. schi.ts Kuznetsk Alatau Yeni.ey Ri.ge Russi.

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Basi. formati.n mechani.ms of Lake Doroni.skoye soda water, East Si.eri., Russi.

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Acta Geochi.i.a 2018年第4期37卷 546-558页

作者： Sv.tlana v. Borzenko Leoni. v. Zamana Lari.a i. Usmanov. i.sti.ute of Natural Resources Ecology and Cryology of Siberian Branch of Russian Academy of Sciences ChitaRussia 672049 Tomsk Department of the Trofi.uk i.sti.ute of Petroleum-Gas Geology and Geophysi.s of Si.eri.n Branch of the Russi.n Academy of Sci.nces Tomsk Russia 634050

The pri.ary sci.nti.i. goal of studyi.g salt lakes i. to better understand the formati.n of small conti.ental- type hydrogeochemi.al systems. Many sci.nti.ts hav. attri.uted the metamorphi.m of the chemi.al composi.i.n of salt lakes to the ev.porati.e concentrati.n of water. How- ev.r, the formati.n of soda water i. i.consi.tent wi.h thi. hypothesi.. Thus, analyzi.g i.trabasi.al bi.chemi.al pro- cesses and water--rocks i.teracti.ns duri.g the ev.porati.e concentrati.n of water allows us to understand the major mechani.ms of the formati.n and ev.luti.n of water com- posi.i.ns. Therefore, the ai. of thi. paper i. to i.enti.y the key processes i.v.lv.d i. the formati.n of the chemi.al composi.i.n of the water i. Lake Doroni.skoye. An analysi. of the di.tri.uti.n of major components shows that Na＋, HCO3-, CO32-, and C1- are domi.ant i. thi. water. Hi.h concentrati.ns of these elements are the result of ev.porati.e water concentrati.n. Calci.m, magnesi.m, and potassi.m are not accumulated because the water i. saturated i. mi.- erals contai.i.g these elements. The mai. barri.r to the growth of the sulfate content of water i. sulfate reducti.n. Thi. process also contri.utes to the addi.i.nal reproducti.n of carbon di.xi.e, whi.h reacts wi.h the products of the hydrolysi. of alumi.osi.i.ates OH- to form HCO3- and CO32-, thus further contri.uti.g to the natural processes of soda formati.n.

关键词： Sali.e lake Sulfate reducti.n Thermodynami. equi.i.ri.m

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Cati.ni. Polymeri.ati.n of i.obutylene and C4 Mi.ed Feed Usi.g Complexes of Lewi. Aci.s wi.h Ethers: A Comparati.e Study

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Chi.ese Journal of Polymer Sci.nce 2019年第9期37卷 891-897页

作者： Dmi.ri. i. Shi.an i.an A. Berezi.nko i.i.a v. v.si.enko Sergei.v. Kostjuk Research i.sti.ute for Physi.al Chemi.al Problems of the Belarusi.n State Uni.ersi.y 14 Leningrads kaya St. Minsk 220006 Belarus Department of Chemi.try Belarusian State University 14 Leningradskaya st. Minsk 220006 Belarus Sechenov.Fi.st Moscow State Medi.al Uni.ersi.y Institute for Regenerative Medicine 8-2 Trubetskaya st. Moscow 119991 Russia

The cati.ni. polymeri.ati.n of C4 mi.ed feed and i.obutylene co-i.i.i.ted by AlCl3xOi.r2,i.uAlC12xnOi.r2, and [emi.]Cl- FeCl3xnOi.r2 ([emi.]Cl: 1 -ethyl-3-methyli.i.azoli.m chlori.e) has been i.v.sti.ated. AlCl3xOi.r2 co-i.i.i.ted cati.ni. polymeri.ati.n of C4 mi.ed feed proceeds at a lower rate than polymeri.ati.n of i.obutylene affordi.g polymers wi.h hi.her molecular wei.ht. Complexes of i.uAlCh wi.h di.i.opropyl ether of di.ferent composi.i.ns are more sui.able co-i.i.i.tors than AlCl3xOi.r2 for the synthesi. of hi.hly reacti.e polyi.obutylene (HR Pi.) from C4 mi.ed feed due to thei. hi.her acti.i.y i. the polymeri.ati.n as well as possi.i.i.y to prepare polyi.obutylenes wi.h lower molecular wei.ht and hi.her content of exo-olefi. end groups. Howev.r, i.uA1C12 needs acti.ati.g v.0} addi.i.n of external water (i.i.i.tor) and/or i.teracti.n wi.h salts hydrates i. order to i.crease the reacti.n rate and the saturated monomer conv.rsi.n.[Emi.]Cl-FeC13/i.r2O i. a qui.e promi.i.g catalyst for the preparati.n of HR Pi. wi.h hi.h exo-olefi. end group content (> 80%) and relati.ely low polydi.persi.y (Mw/Mn v.0} cati.ni. polymeri.ati.n of C4 mi.ed feed. The soni.ati.n of reacti.n mi.ture i. case of usi.g [emi.]Cl-FeCh allowed i.creasi.g the reacti.n rate and decreasi.g the molecular wei.ht.

关键词： Cati.ni. polymeri.ati.n i.obutylene C4 mi.ed feed Hi.hly reacti.e polyi.obutylene

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Nonli.ear dynami.s of MEMS turni.g fork gyroscope

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Sci.nce Chi.a(Technologi.al Sci.nces) 2011年第5期54卷 1078-1083页

作者： Yu. G. MARTYNENKO i. v. MERKURYEv.v. v. PODALKOv i.sti.ute of Mechani.s Lomonosov Moscow State University Moscow Power Engi.eeri.g i.sti.ute (Techni.al Uni.ersi.y)

Accuracy i.prov.ment of MEMS gyros requi.es not only mi.roelectroni. dev.lopment but also the i.v.sti.ati.ns of th mathemati.al model of sensi.i.e element dynami.s. i. the present paper, we study the errors of the v.0}rati.g mi.rogyroscop whi.h ari.e because of nonli.ear dynami.s of a sensi.i.e element. A MEMS tuni.g fork gyroscope wi.h elasti. rods i. consi. ered. Nonli.ear di.ferenti.l equati.ns of bendi.g v.0}rati.ns of sensi.i.e element on the mov.0}g basi. are deri.ed. Free nonli. ear v.0}rati.ns of gyroscopes as the flexi.le rod are studi.d. Nonli.ear dynami.s of gyroscope on the mov.0}g basi. are i.v.sti.gated by asymptoti. two scales method. Sensi.i.e element frequenci.s spli. on two frequenci.s resulted from slowly changi. angular v.loci.y are taken i.to account i. the equati.ns of zero approxi.ati.n. The di.ferenti.l equati.ns for slowly changi. ampli.udes and phases of two normal wav.s of the osci.lati.ns measured by capaci.or gauges and an electroni. contour of th dev.0}e are obtai.ed from the equati.ns of the fi.st approxi.ati.n.

关键词： control of gyro osci.lati.ns spli. of frequenci.s i.enti.i.ati.n av.ragi.g method two scales method stabi.i.y

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Charged parti.le propagati.n through nanostructures and associ.ted radiati.n

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Nuclear Sci.nce and Techni.ues 2004年第2期15卷 65-85页

作者： N.K. ZHEv.GO v. i. GLEBOv i.sti.ute of Hi.h Technology i. Experi.ental Machi.ery Russian Research Centre "Kurchatov Institute" Moscow 123182 RussiaInstitute of High Technology in Experimental MachineryRussian Research Centre "Kurchatov Institute" Moscow 123182 Russia

i. thi. report, usi.g computer si.ulati.ns, we i.v.sti.ate the channeli.g of hi.h-energy charged parti. cles i. nanotube ropes and fulleri.es and esti.ate the capabi.i.y of bent nanocrystals to deflect a parti.le beam. We also di.cuss electromagneti. radiati.n ari.i.g both from the non-uni.orm moti.n of the parti.les i. the electrostati. potenti.l of ali.ned atoms and from the transi.nt polari.ati.n of the medi.m caused by the parti.les.

关键词：纳米结构带电粒子传播方式计算机仿真电磁辐射瞬时偏振固体物理学沟道效应

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The effect of forced osci.lati.ns on the ki.eti.s of wav. dri.t i. an i.homogeneous plasma

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Plasma Sci.nce and Technology 2020年第12期22卷 8-19页

作者： v.i.EROFEEv i.sti.ute of Automati.n&Electrometry of the Si.eri.n Branch of the Russi.n Academy of Sci.nces 1 Koptyug Prosp.630090NovosibirskRussia Nov.si.i.sk State Uni.ersi.y 2 Pirogova Str.NovosibirskRussia

The ki.eti.s i. analyzed of the dri.t of non-potenti.l plasma wav.s i. spati.l posi.i.ns and wav.v.ctors due to plasma's spati.l i.homogenei.y. The analysi. i. based on hi.hly i.formati.e ki.eti. scenari.s of the dri.t of electromagneti. wav.s i. a cold i.ni.ed plasma i. the absence of a magneti. fi.ld(Erofeev.2015 Phys. Plasmas 22 092302) and the dri.t of long Langmui. wav.s i. a cold magneti.ed plasma(Erofeev.2019 J. Plasma Phys. 85 905850104). i. i. shown that the traditi.nal concept of the wav. ki.eti. equati.n does not account for the effects of the forced plasma osci.lati.ns that are exci.ed when the wav.s propagate i. an i.homogeneous *** are hi.hli.hted that account for these osci.lati.ns i. the ki.eti. equati.ns of the abov.menti.ned hi.hly i.formati.e wav. dri.t scenari.s.

关键词： i.formati.eness of plasma ki.eti. scenari. the ensemble method asymptoti. conv.rgence of perturbati.n theori.s correlati.n analysi. of plasma ki.eti.s ki.eti. equati.n of wav. dri.t i. phase space

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FORMATi.N OF LARGE-SCALE TECTONi. ELEMENTS FROM THE POSi.i.N OF CENTRi.UGAL-i.ERTi.L FORCE ACTi.N

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Geotectoni.a et Metallogeni. 2005年第1期29卷 13-33页

作者： Molchanov v. i. Paraev.v. v. Uni.ed i.sti.ute of Geology Geophysics and Mineralogy Siberian Division of Russian Academy of Sciences Novosibirsk 630090 RussiaUnited Institute of Geology Geophysics and Mineralogy Siberian Division of Russian Academy of Sciences Novosibirsk 630090 Russia

We descri.e the earli.r unknown, when appli.d to global tectoni.s, centri.ugal i.erti.l mechani.m of li.hosphere plate mov.0}g under the effect of forces appeari.g as a result of Earth’s planetary rotati.n. The mechani.m stated gi.es an i.si.ht i.to global tectoni.s of plates wi.h the i.di.ect parti.i.ati.n of emanati.n streams whi.h, i. thei. turn, are the deri.ati.es of centri.ugal and i.erti.l forces of planetary moti.n. The appli.ati.n of thi. mechani.m prov.0}es a logi.al explanati.n for the regulari.i.s of global tectogenesi. i.cludi.g the formati.n of mountai. ri.ges mai.ly of submeri.i.nal and sublati.udi.al stri.e, and also the dri.t of conti.ental plates from the east to the west and from the south to the north. The mechani.m clari.i.s the si.ni.i.ance of the Arcti. and the Antarcti. Ci.cles as geodynami. barri.rs.

关键词： formati.n tectoni. element centri.ugal-i.erti.l force secti.n

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Si.ulati.n of detecti.n and scatteri.g of sound wav.s by the lateral li.e of a fi.h

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Chi.ese Physi.s B 2022年第2期31卷 398-404页

作者： v.M Adamyan i.Y Popov.i.v.Bli.ov. v.v.Zav.lni.k Odessa i.i.Mechni.ov.Nati.nal Uni.ersi.y Dvoryanskaya Str.2Odesa65082Ukraine i.MO Uni.ersi.y Kronverkskiy49Saint Petersburg197101Russia Odessa Mi.i.ary Academy 10 Fontanska RoadOdesa 65009Ukraine

A solv.ble model of lateral li.e of a fi.h based on a wav. equati.n wi.h addi.i.nal boundary condi.i.ns on a set of i.olated poi.ts i. *** the framework of thi. model i. i. shown that the rati. of pressures on lateral li.es on di.ferent fi.h flanks,as well as the cross secti.n of sound scatteri.g on both the li.es,strongly depends on angles of i.ci.ence of i.comi.g sound *** strong angular dependence of the pressure rati. seems to be suffi.i.nt for the fi.h to determi.e the di.ecti.ns from whi.h the sound i. comi.g.

关键词： acousti. equati.n poi.t self-adjoi.t perturbati.ns of Laplace operator scatteri.g lateral li.e

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Si.eri.n si.kmoth outbreaks surpassed geocli.ati. barri.r i. Si.eri.n Mountai.s

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Journal of Mountai. Sci.nce 2020年第8期17卷 1891-1900页

作者： KHARUK v.0}cheslav.i. i. Sergei.T. SOLDATOv.v.adimi. v. Sukachev.i.sti.ute of Forest Federal Scientific CenterRussian Academy of ScienceSiberian BranchAcademgorodok 50/28Krasnoyarsk660036 Russia Si.eri.n Federal Uni.ersi.y Svobodny str.79Krasnoyarsk660041 Russia Reshetnev.Si.eri.n State Uni.ersi.y of Sci.nce and Technology Krasnoyarsky rabochy str.31Krasnoyarsk660014 Russia Russi.n Center of Forest Protecti.n Academgorodok 50A/2Krasnoyarsk660036 Russia

Si.eri.n si.kmoth(SSM,Dendroli.us si.i.i.us Tschetv.)i. the most i.portant defoli.tor of Si.eri.n pi.e(Pi.us si.i.i.a Du Tour)and fi.(Abi.s si.i.i.a Ledeb.)***-i.duced SSM outbreaks are one of the major dri.i.g factors of successi.ns wi.hi. the tai.a *** i. suggested that cli.ate change i.pacted the SSM range and li.e *** analyzed the mi.rati.n of alpi.e and northerly SSM outbreak boundari.s i. Si.eri. and the i.pact of the cli.ate v.ri.bles and topography on the outbreak *** used ti.e-seri.s scenes(multi.pectral data,and v.getati.n i.dexes Ev.0}and NDi.)i. combi.ati.n wi.h fi.ld studi.s,cli.ate v.ri.bles,and Gi. *** found that SSM outbreaks i. the area of alpi.e boundary shi.ted about 370 m uphi.l si.ce the mi. of *** outbreak onset was promoted by i.creased dryness and acti.e temperatures and decreased root zone moi.ture content i. the spri.g-early summer *** terrai. topography strongly affected SSM outbreak onset and ***,the outbreak was located at the mi.dle elev.ti.ns on the gentle concav. southeastern slopes,whi.h are the fav.rable i.sect habi.ats between *** the outbreak expanded uphi.l and downhi.l,to steeper slopes,and both concav. and conv.x *** wi.h elev.ti.n range expansi.n,SSM surpassed i.s northern hi.tori.al outbreak boundary:the potenti.l outbreaks’boundary mov.d about 300 km *** warmi.g contri.utes to SSM mi.rati.n i.to former outbreak free coni.er stands located i. hi.hlands and at northern lati.udes.

关键词： i.sect outbreaks Remote sensi.g moni.ori.g i.sect ranges expansi.n Si.eri.n si.kmoth Forest health Coni.er mortali.y

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