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Simulations of ALT-like explosive magnetic devices for ramp compression of materials by magnetically imploded liners

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Matter and Radiation at Extremes 2020年第4期5卷 16-22页

作者： A.M.Buyko G.G.ivanova i.V.Morozova FSUE Russian Federal Nuclear Center–All-Russian Research Institute of Experimental Physics(RFNC-VNIIEF)SarovNizhny Novgorod RegionRussia

Revised simulations of ALT-like devices are *** results from these simulations closely match those from experiments and demonstrate the capabilities of the devices as applied to ramp compression of metals to pressures of 20 Mbar by imploding liners driven by∼10 MG azimuthal magnetic fields(with currents up to 55 MA).These results can be applied to the design of experiments on isentropic compression of materials.

关键词： materials. magnetic Simulation

Unbinding The Pillow Book

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Same Eastern Europe,Different Attitudes towards China——The Differences between the Foreign Policies of Bulgaria and Poland towards China after 1989

作者： Gergana ivanova.

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Same Eastern Europe,Different Attitudes towards China——The...

作者： ivanova Zlatina Petrova 华东师范大学

学位级别：硕士

2019年是中华人民共和国成立70周年。这也标志着中国与保加利亚、中国和波兰建交70周年。从建交时间上来看,保加利亚与波兰只有三天的差距,分别是1949年10月4日与1949年10月7日。彼时,两国正式承认中华人民共和国,并与这个新的国家实体... 详细信息

2019年是中华人民共和国成立70周年。这也标志着中国与保加利亚、中国和波兰建交70周年。从建交时间上来看,保加利亚与波兰只有三天的差距,分别是1949年10月4日与1949年10月7日。彼时,两国正式承认中华人民共和国,并与这个新的国家实体建立了外交关系。近70年来,中保关系和中波关系的发展虽然经历了一些紧张和困难的时期,但他们也不断地加强、改善两国之间的关系。因此,我们现在所拥有的是一个有着相对悠久历史的国家,我们所看到的和期待的对于中国和保加利亚,中国和波兰的双方关系来说,无疑是一个光明且充满希望的未来。这个研究致力于保加利亚和波兰对中国的外交政策。其目的是审视1989年后保加利亚和波兰对华外交政策之间的差异。理由是分析中保关系和中波关系以及保加利亚和波兰对中华人民共和国的态度。我认为保加利亚和波兰之间存在意识形态差异。保加利亚对中国更加务实和友好,而波兰因为更具意识形态性而对中国相对不那么友好。

关键词：中国保加利亚波兰外交政策

Role of GM3 ganglioside in the pathology of some progressive human diseases and prognostic importance of serum anti-GM3 antibodies

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BiOCELL 2021年第6期45卷 1485-1494页

作者： VERA KOLYOVSKA SONYA ivanova DESiSLAVA DRENSKA DiMiTAR MASLAROV RENETA TOSHKOVA institute of Experimental Morphology Pathology and Anthropology with MuseumBulgarian Academy of SciencesSofia1113Bulgaria University Hospital for Neurology and Psychiatry“St.Naum” Sofia1797Bulgaria University First MHAT-Sofia “St.John Krastitel”Neurology ClinicSofia1142Bulgaria Medical University of Sofia Medical College“Y.Filaretova”Sofia1606Bulgaria

Glycosphingolipids(gangliosides)have been characterized as important biological molecules with a key role as regulators in many physiological processes on cellular,tissue,organ,and organism *** deviations in their normal amounts,production,and metabolism are very often related to the development of many multi-factor socially important ***3 ganglioside,as a small molecule,plays important roles in the cascade regulatory pathways in the pathology of many disorders like neurodegenerative diseases,autoimmune diseases,inflammation,diabetes,malignant transformation,and *** GM3 and its derivatives are membrane-bound glycosphingolipids composed of an oligosaccharide head structure containing one sialic acid *** molecules transduce signals involved in cell surface events,including the phosphorylation of transmembrane *** ganglioside is the most widely distributed among tissues,and it serves as a precursor for most of the more complex ganglioside ***3 inhibits the function of fibroblast growth factor receptor,and cell growth is regulated by GM3-enriched ***3 is thought to inhibit immunologic functions,such as the proliferation and production of cytokines by T *** the other hand,the anti-ganglioside antibodies(AGAs)are important in many acquired demyelinating immunemediated neuropathies,like Multiple sclerosis(MS),Guillain–Barrésyndrome(GBS)and its variation,Miller–Fisher syndrome(MFS)and could be suggested as important diagnostic and prognostic markers about the describe diseases and their *** show that the complexes of anti-ganglioside antibodies to GM3(detected by ELiSA)may be useful diagnostic and prognostic tool markers for autoimmune diseases,neurodegenerative disorders,malignancy,diabetes,and *** pilot studies suggest increased serum igG anti-GM3 antibodies titers in patients with secondary progressive MS(SPMS),throat cancer,elder people with diabetes(89–96 years),old Lewis rat

关键词： Biomarkers Serum GM3 Serum anti-GM3 antibodies ELiSA

Cation-anionicpalladium Complexes—New Types of Antitumor, immune Response-modulating and Radioprotective Agents

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贵金属 2012年第A1期33卷 240-242页

作者： EFiMENKO i.A. SHiSHiLOV O.N. ivanova N.A. EROFEEVA O.S. N.S. Kurnakov institute of General and inorganic Chemistry of RAS MoscowRussia

Here we report results of our investigations of new class of bioactive palladium compounds (AH n ) m [PdCl 4 ], which were discovered as a result of systematic study of correlations between composition, structure and bioactivity of different types of platinum metals coordination compounds. For the first time we demonstrated in vivoa possibility of development of palladium compounds, which exceed cisplatin in antitumor activity and do not show immunosuppressive effects, and palladium compounds with immunostimulating and radioprotective activities. Combinations of cytostatic agents or radiation with palladium complexes lead to significant synergism of their activities and high therapeutic efficiency exceeded an efficiency of their separated use.

关键词： palladium chlorides heterocyclic amines antitumor agents immune response-modulating agents radioprotective agents

Technosols on mining wastes in the subarctic: Efficiency of remediation under Cu-Ni atmospheric pollution

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international Soil and Water Conservation Research 2019年第3期7卷 297-307页

作者： Marina V.Slukovskaya Viacheslav i.Vasenev Kristina V.ivashchenko Dmitry V.Morev Svetlana V.Drogobuzhskaya Liubov A.ivanova irina P.Kremenetskaya i.V.Tananaev institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials Kola Science CentreRussian Academy of Sciences184209Academgorodok 26aApatityMurmansk RegionRussia Department of Landscape Design and Sustainable Ecosystems RUDN University117198Miklykho-Maklaya str.8MoscowRussia institute of Physicochemical and Biological Problems in Soil Science Russian Academy of Sciences142290Institutskaya str.2PushchinoMoscow RegionRussia Department of Ecology Russian State Agrarian University-Moscow Timiryazev Agricultural Academy127550Timiryazevskaya str.49MoscowRussia N.A.Avrorin Polar-Alpine Botanical Garden-institute Kola Science CentreRussian Academy of Sciences184209Academgorodok 18aApatityMurmansk RegionRussia

Tne copper-nickel factory's emissions in the Murmansk region,Russia,led to the degradanon of plant cover and topsoil with the subsequent formation of industrial *** this study,the industrial barrens were remediated by means of Technosol engineering,when grasses were sown on the two different types of mining wastes (carbonatite and serpentinite-magnesite) covered by hydroponic *** serpentinite-magnesite waste was significantly different from the carbonatite waste in the content of silicon (Si) and manganese (Mn),pH,and *** wastes had an alkaline pH level and high content of calcium (Ca) and magnesium (Mg).The vegetation and Technosol properties at the remediated sites were analyzed in 2017 and compared to the initial state (2010 year) to assess the efficiency of the long-term *** quality and sustainability of Technosols based on the serpentinite-magnesite wastes were substantially higher compared to the carbonatite-based *** and a projective cover of the grass community depended on Si content in the original mining waste and were found to be higher in the serpentinite-magnesite *** content of organic carbon and its fractions,microbial biomass and basal respiration after seven years of Technosol evolution was comparable to natural *** parameters were directly related to plant cover state and were inversely proportional to copper (Cu) content in *** Technosol development led to the reduction of nickel (Ni) and Cu migration in soil-plant ecosystems due to neutralization and adsorption properties of mining wastes and phytostabilization by underground parts of grass *** Technosol development in its early stage of pedogenesis indicates the efficiency of applied remediation technology to the degraded acidic soil under the conditions of industrial atmospheric pollution.

关键词： industrial barrens Metals Phytostabilization Soil organic carbon Basal respiration Pedogenesis

improving HER2 testing reproducibility in HER2-low breast cancer

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Cancer Drug Resistance 2022年第4期5卷 882-888页

作者： Elham Sajjadi Konstantinos Venetis Mariia ivanova Nicola Fusco Division of Pathology IEOEuropean Institute of Oncology IRCCSMilan 20141Italy Department of Oncology and Hemato-Oncology University of MilanMilan 20122Italy

HER2 is a pillar biomarker in breast cancer,and it is assessed by immunohistochemistry(iHC)using a three-tier scoring system and reflex in situ hybridization(iSH)for iHC score 2+.Novel HER2-directed antibody-drug conjugates have demonstrated significant antitumor activity in breast cancers with low levels of HER2 expression,*** score 1+or iSH-negative iHC score 2+.Both primary and acquired resistance to anti-HER2 therapies remains a challenge in the treatment of breast cancers according to the HER2 positivity ***,the ability to precisely discriminate among HER2-zero,HER2-low,and HER2-positive breast cancers is no longer a mere academic ***2 testing criteria,guidelines,and quality controls are re-gaining momentum for this new clinical ***,all preanalytical and analytical variables that might trouble the sensitivity and reproducibility of this test should be carefully considered to address all possible issues and open all possible therapeutic opportunities for breast cancer patients.

关键词： Breast cancer biomarkers HER2 HER2 low targeted therapy antibody-drug conjugates immunohistochemistry iSH

A detailed reconstruction of changes in the factors and parameters of soil erosion over the past 250 years in the forest zone of European Russia(Moscow region)

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international Soil and Water Conservation Research 2022年第1期10卷 149-160页

作者： Andrey Zhidkin Daria Fomicheva Nadezhda ivanova Tomas Dostal Alla Yurova Mikhail Komissarov Josef Krasa V.V.dokuchaev soil science institute pyzhevskiy pereulok 7moscow119017russian federation Faculty of geography lomonosov moscow state universityleninskie gorygsp-1moscow119991russian federation Department of landscape water conservation faculty of civil engineeringczech technical university in praguethakurova 7prague16629czech republic Ufa institute of biology ufrc russian academy of sciencespr.oktyabrya 69ufa450054russian federation

Accelerated soil erosion is a major threat to soil,and there are great variations in the rate of soil erosion over time due to natural and human-induced *** temperate forest zone of Russia is character-ized by complex stages of land-use history(*** urbanization,agricultural development,land abandonment,etc.).We have for the first time estimated the rates of soil erosion by the WaTEM/SEDEM model(rainfall erosion)and by a regional model(snowmelt erosion)over the past 250 years(from 1780 to 2019)for a 100-km2 study site in the Moscow region of *** calculations were made on the basis of a detailed historical reconstruction of the following factors:the location of the arable land,crop rotation,the rain erosivity factor,and the maximum snow water *** area of arable land has decreased more than 3.5-fold over the past 250 *** the end of the 20th century,the rates of gross erosion had declined more than 5.5-fold(from 28×10^(3) to 5×10^(3) t·ha^(-1)yr^(-1))in comparison with the end of the 18th *** in the boundaries of arable land and also the relief features had led to a significant intra-slope accumulation of *** a result of sediment redeposition within the arable land,the variation in net soil erosion was significantly lower than the variation in gross soil *** changes in arable land area and in crop composition are the factors that have to the greatest extent determined the changes in soil erosion in this territory.

关键词： Anthropogenic soil erosion Soil erosion history Crop rotation Magnetic tracer method WaTEM/SEDEM

Effect of biochar aging in agricultural soil on its wetting properties and surface structure

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Biochar 2023年第1期5卷 1288-1304页

作者： Natalia ivanova Gardoon Luqman Obaeed Obaeed Farid Sulkarnaev Natalya Buchkina Alexey Gubin Andrei Yurtaev Photonics and Microfluidics Lab X-BIO InstituteUniversity of Tyumen6 Volodarskogo625003 TyumenRussia international integrated Research Lab for Climate Change Land Use and BiodiversityX-BIO InstituteUniversity of Tyumen6 Volodarskogo625003 TyumenRussia Department of Soil Physics Physical Chemistry and BiophysicsAgrophysical Research InstituteGrazhdansky Pr.14195220 St.PetersburgRussia X-BiO institute University of Tyumen6 Volodarskogo625003 TyumenRussia Nanomaterials and Nanoelectronics Laboratory CNIEUniversity of Tyumen6 Volodarskogo625003 TyumenRussia

Biochar wettability and ability to accumulate moisture inside the porous space are crucial for improving soil fertility,regulating soil water balance,and regulating ***,a long-term interaction of biochar with agricultural soils may drastically alter the wetting properties and,eventually,influence water holding capacity and the structure of *** this work,the structure and wetting properties of biochar samples after 6-year long exposure to a sandy loam Spodosol with a crop rotation and mineral fertilizers application were *** was found that the elemental composition of the aged biochars was richer and more"soil-like",which is explained by the presence of the mineral crust on the biochar *** temporal evolution of biochar in the soil without any mineral fertilizer application resulted in significant improvement of its surface wettability due to the effects of various environmental *** lateral surface of biochar after 6-year interaction with the soil changes into a loose porous layer in a form of grooved base filled with adherent mineral soil and clay ***,the application of the mineral fertilizer to the soil resulted in decreased wettability of the biochar lateral surfaces due to a decrease in the polar component of surface energy and the crusting of the surface with fine material,which blocks the pore space of the *** a result,water capacity of the biochar from the treatment with the fertilizer decreased compared to the biochar samples collected from the soil without the fertilizer *** radial biochar surfaces of both types of samples collected from the soil were open vessels filled with soil particles that slow down complete wetting and water *** treatment of the biochar samples with surfactants drastically increased wettability of lateral surface and water absorption capacity of control samples as compared to the samples collected from the *** obtained results support the idea t

关键词： Light-textured Spodosol 6-year field experiment Biochar surface Wettability Water absorbing Soil capacity