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Endoscopic ultrasound-guided tissue sampling induced pancreatic duct leak resolved by the placement of a pancreatic stent:A case report

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World Journal of Clinical Cases 2024年第9期12卷 1677-1684页

作者： ki-Hyun kim Chang Hwan Park Eunae Cho Yohan lee Department of internal Medicine Chonnam National University HospitalGwangju 61469South Korea Department of Gastroenterology Chonnam National University HospitalGwangju 61469South Korea

BACKGROUND Pancreatic ductal leaks complicated by endoscopic ultrasonography-guided tissue sampling(EUS-TS)can manifest as acute pancreatitis.CASE SUMMARY A 63-year-old man presented with persistent abdominal pain and weight loss.Diagnosis:laboratory findings revealed elevated carbohydrate antigen 19-9(5920 U/ml)and carcinoembryonic antigen(23.7 ng/ml)levels.Magnetic resonance imaging of the pancreas revealed an approximately 3 cm ill-defined space-occupying lesion in the inferior aspect of the head,with severe encasement of the superior mesenteric artery.Pancreatic ductal adenocarcinoma was confirmed after pathological examination of specimens obtained by EUS-TS using the fanning method.interventions and outcomes:The following day,the patient experienced severe abdominal pain with high amylase(265 U/l)and lipase(1173 U/l)levels.Computed tomography of the abdomen revealed edematous wall thickening of the second portion of the duodenum with adjacent fluid collections and a suspicious leak from either the distal common bile duct or the main pancreatic duct in the head.Endoscopic retrograde cholangiopancreatography revealed dye leakage in the head of the main pancreatic duct.Therefore,a 5F 7 cm linear plastic stent was deployed into the pancreatic duct to divert the pancreatic juice.The patient’s abdominal pain improved immediately after pancreatic stent insertion,and amylase and lipase levels normalized within a week.Neoadjuvant chemotherapy was then initiated.CONClUSiON Using the fanning method in EUS-TS can inadvertently cause damage to the pancreatic duct and may lead to clinically significant pancreatitis.Placing a pancreatic stent may immediately resolve acute pancreatitis and shorten the waiting time for curative therapy.When using the fanning method during EUSTS,ductal structures should be excluded to prevent pancreatic ductal leakage.

关键词： Endoscopic ultrasound-guided tissue sampling Pancreatitis Pancreatic duct leak Pancreatic stent Case report

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influence of overhanging tool length and vibrator material on electromechanical impedance and amplitude prediction in ultrasonic spindle vibrator

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第4期25卷 292-310页

作者： Rendi KURNiAWAN Moran XU Min ki CHOO Shuo CHEN Yein KWAK' Jielin CHEN Saood Ali Hanwei TENG Pil Wan HAN Gi Soo kiM Tae Jo KO Precision Machining laboratory Department of Mechanical Engineering Yeungnam UniversityGyeongsansiGyeongbuk-doRepublic of Korea Korea Electrotechnology Research institute(KERi) ChangwonsiGyeongsangnam-doRepublic of Korea KASWiN Co. LtdChangwon-siGyeongsangnamdoRepublic of Korea

This study presents the development of an ultrasonic transducer with a radius horn for an ultrasonic milling spindle(UMS)system.The ultrasonic transducer was intended to have a working frequency of approximately 30 kHz.Two different materials were considered in the study:stainless steel(SS 316l)and titanium alloy(Ti-6Al-4V).Titanium alloy gave a higher resonance frequency(33 kHz)than stainless steel(30 kHz)under the same preload compression stress.An electromechanical impedance simulation was carried out to predict the impedance resonance frequency for both materials,and the effect of the overhanging toolbar was investigated.According to the electromechanical impedance simulation,the overhanging toolbar length affected the resonance frequency,and the error was less than 3%.Harmonic analysis confirmed that the damping ratio helps determine the resonance amplitude.Therefore,damping ratios of 0.015-0.020 and 0.005-0.020 were selected for stainless steel and titanium alloy,respectively,with an error of less than 1.5%.Experimental machining was also performed to assess the feasibility of ultrasonic-assisted milling;the result was a lesser cutting force and better surface topography of Al 6061.

关键词： Ultrasonic spindle Ultrasonic vibration assisted-milling(UVAM) 1-degree of freedom(DOF) Frequency Amplitude Milling

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氮掺杂对环境空气中TiO_(2)纳米催化剂抗甲醛光催化矿化的影响

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Chinese Journal of Catalysis 2024年第4期59卷 303-323页

作者： Dae-Hwan lim Aadil Bathla Hassan Anwer Sherif AYounis Danil WBoukhvalov ki-Hyun kim 汉阳大学土木与环境工程系首尔韩国国立科技大学环境工程系伊斯兰堡巴基斯坦埃及石油研究所分析与评估部开罗埃及南京林业大学材料物理与化学研究所理学院江苏南京乌拉尔联邦大学物理与技术研究所叶卡捷琳堡俄罗斯

通过氮掺杂TiO_(2)(N-TiO_(2))浸渍蜂窝过滤器构建了一系列原型光催化空气净化器(AP(N_(x)-C_(y)))系统,并用于在UV-lED光(1 W)照射条件下光催化分解0.5-5 ppm甲醛(CH_(2)O)蒸汽.在上述催化过滤器系统中,Nx和Cy分别代表N/Ti摩尔比(0-20)... 详细信息

通过氮掺杂TiO_(2)(N-TiO_(2))浸渍蜂窝过滤器构建了一系列原型光催化空气净化器(AP(N_(x)-C_(y)))系统,并用于在UV-lED光(1 W)照射条件下光催化分解0.5-5 ppm甲醛(CH_(2)O)蒸汽.在上述催化过滤器系统中,Nx和Cy分别代表N/Ti摩尔比(0-20)和N-TiO_(2)浓度(2-20 mg ml^(-1)).光催化分解实验结果表明,AP(N_(10)-C_(10))的性能最好,其催化CH2O转化为CO_(2)的转化率最高,循环反应10次后CO_(2)产率仍达到89.2%,在干燥空气中的清洁空气输送速率为9.45 l min^(-1).N10-C10的电荷载流子寿命(τa:1.70 ns)优于其他样品(如纯TiO_(2)的电荷载流子寿命为1.37 ns),这表明N缺陷(No)有助于降低带隙(3.10 eV)和产生氧空位OVs-Ti^(3+),这与密度泛函理论(DFT)模拟结果一致.采用原位漫反射红外傅里叶变换、电子顺磁共振和DFT分析等多种方法研究了CH_(2)O的光催化氧化途径.结果表明,氧化过程涉及多个能量有利的中间步骤(例如CH2O以CH_(2)O_(2)的形式在TiO_(2)-OV{110}表面的桥连O/OH基团上发生放热共价吸附,随后通过催化脱氢/氧化反应直接生成CO_(2):CH_(2)O_(2)/HCOO^(-)+•OH→H_(2)O+CO_(2)).这些步骤与具有N杂质的{101}表面上化学活性Ti原子的态密度计算结果一致.预计No缺陷和OVs的存在将通过降低活化能垒来影响反应能量和中间产物,从而在加湿条件下实现有效的矿化.综上,本文为设计和构建先进的光催化系统,并用于环境空气中醛类挥发性有机物(VOCs)的有效矿化提供了新思路.

关键词：光催化蜂窝过滤器甲醛氮掺杂TiO_(2) 密度泛函理论计算催化反应途径空气净化

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碱改性铜锰尖晶石室温催化氧化空气中甲醛

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Chinese Journal of Catalysis 2024年第5期60卷 337-350页

作者： Yongbiao Hua Kumar Vikrant ki-Hyun kim Philippe M.Heynderickx Danil W.Boukhvalov 汉阳大学土木与环境工程系韩国首尔根特大学国际校区环境与能源研究中心催化与表征材料工程韩国仁川根特大学生物科学工程学院绿色化学与技术系比利时根特京林业大学理学院材料物理与化学研究所江苏南京210037 拉尔联邦大学物理与技术研究所俄罗斯叶卡捷琳堡

甲醛(FA)作为一种有致癌风险的有害污染物,在室内环境中普遍存在.为了高效去除甲醛,催化氧化技术成为了一种既经济又节能的选择,它不仅能降低材料成本(例如避免使用贵金属),也能在无光和室温的条件下进行.本文制备了一种成本效益高的碱... 详细信息

甲醛(FA)作为一种有致癌风险的有害污染物,在室内环境中普遍存在.为了高效去除甲醛,催化氧化技术成为了一种既经济又节能的选择,它不仅能降低材料成本(例如避免使用贵金属),也能在无光和室温的条件下进行.本文制备了一种成本效益高的碱改性锰酸铜尖晶石(CuMn^(2)O_(4))催化剂,并用于甲醛催化氧化反应中.实验结果表明,采用碱(1 mol l^(-1)氢氧化钾)改性的CuMn^(2)O_(4)(1-CuMn^(2)O_(4))作为催化剂,在室温条件下,当甲醛浓度为50 ppm,气体空速为4777 h^(-1)时,甲醛转化率(XFA)达到100%;此外,在甲醛转化率为10%时,其稳态反应速率达到了8.18×10^(-2) mmol g^(-1) h^(-1).原位漫反射红外傅立叶变换光谱结果表明,在催化剂的作用下,甲醛分子经过二氧亚甲基和甲酸酯中间体的转化,最终被氧化为水和二氧化碳.进一步结合密度泛函理论模拟发现,1-CuMn^(2)O_(4)具有较高的催化氧化甲醛性能,可归因于甲醛分子更牢固地吸附在1-CuMn^(2)O_(4)表面,甲醛吸附所需的能量较低,以及最终产物从催化剂表面脱附所需的能量也较低的综合效应.本研究为在无光和室温条件下,高效去除空气中甲醛提供了新型高效、成本效益高且无需贵金属的催化剂,从而为室内空气净化提供了新的科学见解.

关键词：甲醛碱修饰锰酸铜尖晶石催化氧化室内空气

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Study of Some Biodemographic Parameters of Caryedon serratus Olivier (Coleoptera: Chrysomelidae) insect Pest of Tamarind (Tamarindus indica lin.) Fruit, in Burkina Faso

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Advances in Entomology 2024年第2期12卷 67-77页

作者： kilo Francine Marina ki Koï Wenceslas Kam Emmanuel Kabore Antoine Sanon Zakaria ilboudo laboratoire d’Entomologie Fondamentale et Appliqué e (LEFA) UFR/SVT Universit&eacute Joseph KI-ZERBO Ouagadougou Burkina Faso institut Supé rieur du D&eacuteveloppement Durable Universit&eacute de Fada N’gourma Fada N’gourma Burkina Faso

The lack of food security leads us to turn to the riches of the forest, namely non-timber forest products (NTFP) and timber forest products (TFP). in Burkina, these products are a source of income for families, improving their living conditions. Tamarindus indica l. that is a NFTP, is widely used in both rural and urban areas. Unfortunately, tamarind is subject to attack by Caryedon serratus. its biological activity begins on the fruit before the harvest. The aim of our study is to evaluate some biodemographic parameters of the insect pest C. serratus Olivier. First100 healthy T. indica pods were placed in contact with ten pairs of C. serratus for 24 hours. 25 pods, each carrying a maximum of two eggs, were divided into five batches of 5 pods. Then a pair of C. serratus aged less than 24 h was placed in contact with 4 healthy pods for 24 h. Every day, the pair was removed and transferred to another box containing 4 new healthy pods. A total of 20 replicates were performed. The results showed that C. serratus has an average lifespan of 14 days. However, the female (16 days) lived longer and laid an average of 34 eggs during her lifetime. The egg-laying period lasted 14 days, the number of eggs increased until reaching a maximum peak on the 4th day. C. serratus has an embryonic development time of 3 days and an emergence rate of 66.63%. However, the weight of males and females differed significantly (p = 0.0108). We found an intrinsic rate of natural increase of 0.12 and a population doubling time was 5.68 days. These results have enabled us to gain a better understanding of its development cycle and its capacity for regeneration. This allows us to implement control strategies for better stock protection.

关键词： Biodemographic Parameters Stock Caryedon serratus Tamarindus indica

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COViD-19 vaccine hesitancy and related factors among primary healthcare workers in a district of istanbul:a cross-sectional study from Turkey

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Family Medicine and Community Health 2022年第2期10卷 32-39页

作者： Haticeikiışık Mehmet Akif Sezerol Yusuf Taşçı işıl Maral Department of Public Health Faculty of MedicineIstanbul Medeniyet UniversityIstanbulTurkey Public Health Department Institute of Health SciencesIstanbul UniversityIstanbulTurkey

Objectives This study aimed to determine the COViD-19 risk perceptions,vaccination intentions and predictive factors of family physicians and family healthcare staff working in primary care inÜsküdar.Design A cross-sectional study was performed using an online questionnaire to determine the demographic and general characteristics of the participants and their willingness to be vaccinated.Setting An online questionnaire was applied to family physicians and family health workers working in primary care family health centres inÜsküdar between 25 and 29 December 2020.Multivariate analysis was performed to identify independent predictors of the willingness of individuals to be vaccinated.Participants Out of 323 health workers working in 44 family health centres in the district,a total of 276 health workers were reached,including 126 physicians(n=158,79.7%)and 150 midwives/nurses(n=165,90.9%)(response rate 85.4%).Results 50.4%(n=139)of the healthcare workers were willing to have the COViD-19 vaccine,29%(n=80)were undecided and 20.7%(n=57)refused the vaccine.The rate of acceptance to be vaccinated was higher in physicians,in men and in those who had not received a seasonal influenza vaccination regularly each year.Conclusions Half of the primary healthcare workers,one of the high-risk groups in the pandemic,were hesitant or refused to be vaccinated for COViD-19.Knowing the factors affecting the vaccine acceptance rates of healthcare professionals can be considered one of the most strategic moves in reaching the target of high community vaccination rates.For evidence-based planning in vaccination studies,there is a need to investigate the reasons for COViD-19 vaccine acceptance by healthcare workers at all levels.

关键词： nurse workers district

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Predicting elastic properties of hard-coating alloys using ab-initio and machine learning methods

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npj Computational Materials 2022年第1期8卷 139-148页

作者： H.levämäki F.Tasnádi D.G.Sangiovanni l.J.S.Johnson R.Armiento i.A.Abrikosov Department of Physics Chemistry and BiologyLinköping UniversitySE-58183LinköpingSweden Sandvik Coromant S-12680StockholmSweden Materials Modeling and Development laboratory National University of Science and Technology‘MISIS’119049MoscowRussia

Accelerated design of hard-coating materials requires state-of-the-art computational tools,which include data-driven techniques,building databases,and training machine learning models.We develop a heavily automated high-throughput workflow to build a database of industrially relevant hard-coating materials,such as binary and ternary nitrides.We use the high-throughput toolkit to automate the density functional theory calculation workflow.We present results,including elastic constants that are a key parameter determining mechanical properties of hard-coatings,for X_(1−x)Y_(x)N ternary nitrides,where X,Y∈{Al,Ti,Zr,Hf}and fraction x=0,1/4,1/2,3/4,1.We also explore ways for machine learning to support and complement the designed databases.We find that the crystal graph convolutional neural network trained on ordered lattices has sufficient accuracy for the disordered nitrides,suggesting that existing databases provide important data for predicting mechanical properties of qualitatively different types of materials,in our case disordered hard-coating alloys.

关键词： coating alloys ternary

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Atlas of Elbow Soft Tissue Pathologies Using Magnetic Resonance imaging at the Saint Camille Hospital in Ouagadougou and the Polyclinique Notre Dame de la Paix (Burkina Faso)

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Open Journal of Medical imaging 2024年第2期14卷 43-55页

作者： Milckisédek Judicaël Marouruana Some Pakisba Ali Ouedraogo Aïda ida Tankoano Wendiwoumyan Judicaël Congo Bassirou kindo Bénilde Marie Ange Kambou Rabiou Cisse Department of Medical imaging The Ouahigouya Regional University Hospital University of Ouahigouya Burkina Faso Department of Medical imaging Souro Sanou University Hospital Nazi Boni University Bobo Dioulasso Burkina Faso Department of Medical imaging Bogodogo University Hospital Joseph Ki Zerbo University Ouagadougou Burkina Faso Department of Medical imaging Yalgado Oudraogo University Hospital Joseph Ki Zerbo University Ouagadougou Burkina Faso

introduction: The elbow is a superficial joint, particularly exposed to direct impact, forced movement, and overstrain. Our work aimed to study magnetic resonance imaging (MRi) pathologies of the soft tissues of the elbow through illustrative cases. Methodology: This was a retrospective and prospective cross-sectional study covering a period of one year, from June 2020 to June 2021, at the Saint Camille Hospital in Ouagadougou and the Polyclinique Notre Dame de la Paix. Results: in general, this study found that the pathologies diagnosed on MRi were lateral epicondylitis, subcutaneous type V elbow lipoma and liposarcoma, anteromedial cortical fracture of the radial cup, cortical detachment fracture of the lateral epicondylitis, medial epicondylitis, villonodular articular synovitis, simple dermo-hypodermatitis, sequellar fibrosis of the ulnar nerve, Workman's syndrome (median and ulnar nerves) and osteoarthritis of the elbow. lateral epicondylitis was the most frequent pathology, and most patients consulted for elbow pain predominantly associated with pressure on the epicondyle, with relative functional impotence and, occasionally, elbow swelling. Conclusion: MRi, as a complement to ultrasound and radiography, remains the most informative examination for exploring soft-tissue pathologies of the elbow.

关键词： Magnetic Resonance imaging Soft Tissue Elbow

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Plant-derived nanovesicles: Current understanding and applications for cancer therapy

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Bioactive Materials 2023年第4期22卷 365-383页

作者： Ngoc Phung ly Hwa Seung Han Myungsuk kim Jae Hyung Park ki Young Choi Natural Product informatics Research Center Korea Institute of Science and Technology(KIST)Gangneung25451Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolUniversity of Science and Technology(UST)Seoul02792Republic of Korea School of Chemical Engineering College of EngineeringSungkyunkwan UniversitySuwon16419Republic of Korea Department of Health Sciences and Technology SAIHSTSungkyunkwan UniversitySeoul06351Republic of Korea Biomedical institute for Convergence at SKKU Sungkyunkwan UniversitySuwon16419Republic of Korea

Plant-derived vesicles(PDVs)are membranous structures that originate from plant cells and are responsible for multiple physiological and pathological functions.in the last decade,PDVs have gained much attention for their involvement in different biological processes,including intercellular communication and defense response,and recent scientific evidence has opened a new avenue for their applications in cancer treatment.Nevertheless,much remains unknown about these vesicles,and current research remains inconsistent.This review aims to provide a comprehensive introduction to PDVs,from their biological characteristics to purification methods,and to summarize the status of their potential development for cancer therapy.

关键词： Plant-derived vesicles Extracellular vesicles Cancer therapy Anti-cancer Drug delivery

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Rice pollen-specific OsRAlF17 and OsRAlF19 are essential for pollen tube growth

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植物学报:英文版 2023年第9期65卷 2218-2236页

作者： Eui‐Jung kim Ji‐Hyun kim Woo‐Jong Hong Eun Young kim Myung‐Hee kim Su Kyoung lee Cheol Woo Min Sun Tae kim Soon ki Park ki‐Hong Jung Yu‐Jin kim Graduate School of Green Bio‐Science&Crop Biotech institute Kyung Hee UniversityYongin 17104Republic of Korea Department of life Science and Environmental Biochemistry Life and Industry Convergence Research InstitutePusan National UniversityMiryang 50463Republic of Korea Department of Smart Farm Science Kyung Hee UniversityYongin 17104Republic of Korea School of Applied Biosciences Kyungpook National UniversityDaegu 41566Republic of Korea Genomics Division Department of Agricultural Bio‐ResourcesNational Institute of Agricultural SciencesRural Development AdministrationJeonju 54874Republic of Korea Department of Plant Bioscience Pusan National UniversityMiryang 50463Republic of Korea Research Center for Plant Plasticity Seoul National UniversitySeoul 08826Republic of Korea

Pollen tube growth is essential for successful double fertilization, which is critical for grain yield in crop plants. Rapid alkalinization factors(RAlFs) function as ligands for signal transduction during fertilization. However, functional studies on RAlF in monocot plants are lacking.Herein, we functionally characterized two pollen-specific RAlFs in rice(Oryza sativa) using multiple clustered regularly interspaced palindromic repeats(CRiSPR)/CRiSPR-associated protein 9-induced loss-of-function mutants,peptide treatment, expression analyses, and tag reporter lines. Among the 41 RAlF members in rice, OsRAlF17 was specifically expressed at the highest level in pollen and pollen tubes.Exogenously applied OsRAlF17 or OsRAlF19peptide inhibited pollen tube germination and elongation at high concentrations but enhanced tube elongation at low concentrations, indicating growth regulation. Double mutants of OsRAlF17 and OsRAlF19(ralf17/19) exhibited almost full male sterility with defects in pollen hydration, germination, and tube elongation,which was partially recovered by exogenous treatment with OsRAlF17 peptide. This study revealed that two partially functionally redundant OsRAlF17 and OsRAlF19 bind to Oryza sativa male-gene transfer defective 2(OsMTD2) and transmit reactive oxygen species signals for pollen tube germination and integrity maintenance in rice. Transcriptomic analysis confirmed their common downstream genes, in osmtd2 and ralf17/19. This study provides new insights into the role of RAlF, expanding our knowledge of the biological role of RAlF in regulating rice fertilization.

关键词： CRiSPR-Cas9 CrRlK1l monocot Oryza sativa pollen tube growth rapid alkalinization factor(RAlF)

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