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Effectiveness of external prestressing in enhancing the non-ductile hanger failure mechanism in reinforced concrete inverted T-beams

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Frontiers of Structural and civil Engineering 2024年第7期18卷 1050-1065页

作者： Ahmed M.ATTA Reda N.BEHiRY Mohammed i.HARAZ Structural Engineering Department Faculty of EngineeringTanta UniversityTanta 33511Egypt Nile Higher institute for Engineering and Technology Mansoura 11001Egypt

Recently,inverted T-beams have been used in reinforced concrete(Rc)bridges to support transverse precast *** T-beams,contrary to practice with conventional beams,are loaded on the flanges upper *** loading configuration causes hanger failure due to the generation of vertical tensile stresses near the bottom of the *** key purpose of this study is to investigate the efficiency of vertical external prestressing stainless-steel bars in mitigating non-ductile hanger failure in reinforced concrete inverted *** experimental study on six inverted-T beams,including two un-strengthened specimens,was carried *** study showed that the value of the prestressing level had a considerable impact on the performance of hanger mechanism in relation to crack pattern,ultimate loads,cracking behavior,load-deflection,strains,and *** experimental results indicated that the suggested method for strengthening inverted T-beams had efficacy in reducing the seriousness of the non-ductile hanger failure and resulted in a strength increase of up to 53% when compared to that of the un-strengthened ***,two analytical models for estimating the hanger capacity and the average crack width of the strengthened Rc inverted T-beams were *** models that were proposed exhibited a high degree of agreement with the experimental results.

关键词： Rc bridges inverted T-beams strengthening hanger failure external prestressing

immunotherapy in gastric cancer with liver metastasis:challenges and opportunities

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1513-1516页

作者： Murat Bardakçi Yakup Ergun Department of Medical Oncology Diyarbakır Gazi Yasargil Training and Research HospitalDiyarbakir 021000KayapinarTürkiye Department of Medical Oncology Antalya City HospitalAntalya 07080Türkiye

in this editorial,we review the article by Liu et al published in the World Journal of Gastrointestinal Surgery investigating the efficacy and safety of immunotherapy in patients with gastric cancer(Gc)and liver ***,the fifth most com-monly diagnosed malignancy worldwide,presents a significant challenge due to its multifactorial etiology and a grim prognosis for unresectable or recurrent *** advent of immune checkpoint inhibitors(icis)has revolutionized oncology;yet liver metastasis has been associated with reduced response rates,progression-free survival,and overall survival in various *** che-ckMate-649 and KEYNOTE-859 trials demonstrated promising results with icis in advanced Gc,particularly in patients with liver ***,a meta-analysis of liver metastatic solid tumors revealed worse outcomes with icis,high-lighting the need for further *** combined therapies,including icis with local treatments,show promise in improving outcomes,the nuanced landscape of icis in liver metastatic Gc necessitates continued research for robust *** current contradictions in the literature underscore the impor-tance of cautious interpretation and the exploration of tailored approaches to enhance clinical efficacy in this challenging patient population.

关键词： Gastric cancer Liver metastasis immunotherapy immune checkpoint in-hibitors Transarterial chemoembolization Tumor microenvironment

VR-based digital twin for remote monitoring of mining equipment:Architecture and a case study

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虚拟现实与智能硬件（中英文） 2024年第2期6卷 100-112页

作者： Jovana PLAVŠiĆ ilija MiŠKOViĆNorman BKeevil Norman B.Keevil institute of Mining Engineering University of British ColumbiaVancouverBC V6T 1Z4Canada

Background Traditional methods for monitoring mining equipment rely primarily on visual inspections,which are time-consuming,inefficient,and *** article introduces a novel approach to monitoring mission-critical systems and services in the mining industry by integrating virtual reality(VR)and digital twin(DT)***-based DTs enable remote equipment monitoring,advanced analysis of machine health,enhanced visualization,and improved decision *** This article presents an architecture for VR-based DT development,including the developmental stages,activities,and stakeholders involved.A case study on the condition monitoring of a conveyor belt using real-time synthetic vibration sensor data was conducted using the proposed *** study demonstrated the application of the methodology in remote monitoring and identified the need for further development for implementation in active mining *** article also discusses interdisciplinarity,choice of tools,computational resources,time and cost,human involvement,user acceptance,frequency of inspection,multiuser environment,potential risks,and applications beyond the mining *** The findings of this study provide a foundation for future research in the domain of VR-based DTs for remote equipment monitoring and a novel application area for VR in mining.

关键词： Virtual reality Digital twin condition monitoring Mining equipment

Solar-driven cO_(2) conversion to methane and methanol using different nanostructured cu_(2)O-based catalysts modified with Au nanoparticles

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Journal of Energy chemistry 2024年第4期91卷 287-298页

作者： João Angelo Lima Perini Lilian D.Moura Torquato Juliana Fde Brito Gustavo A.Andolpho Mateus A.Gonçalves Leonardo D.De Angelis Lucas D.Germano Susana i.córdoba de Torresi Teodorico c.Ramalho Maria V.Boldrin Zanoni São Paulo State University(UNESP) Institute of ChemistryRua Prof.Francisco Degni55AraraquaraSP 14800-060Brazil National institute of Alternative Technologies for Detection Toxicological Evaluation and Removal of Micropollutants and Radioactive Substances(INCT-DATREM)São Paulo State University(UNESP)Institute of ChemistryRua Prof.Francisco Degni55AraraquaraSP 14800-060Brazil Laboratory of Molecular Modelling Department of ChemistryNatural Sciences InstituteFederal University of LavrasLavrasMG 37200-900Brazil Department of chemistry Faculty of ScienceUniversity of Hradec KrálovéHradec Králové50003Czech Republic instituto de Química Universidade de São PauloAv.Prof.Lineu Prestes 74805508-080São PauloSPBrazil

This work describes the use of TiO_(2)nanotubes-based electrodes(TNT)modified with cu_(2)O nanostructures and gold nanoparticles for the photoelectroreduction of cO_(2)to produce value-added compounds.A thin layer of polydopamine was used as both an adherent agent and an electron transfer mediator,due to itsπ-conjugated electron *** highest production yield was achieved using a TNT@PDA/Nc/Au40%electrode,with Faradaic efficiencies of 47.4%(110.5μM cm^(-2))and 27.8%(50.4μM cm^(-2))for methanol and methane,*** performance of the photoelectrodes was shown to be cu_(2)O facet-dependent,with cubic structures leading to greater conversion of cO_(2)to methanol(43%)and methane(27%),compared to the octahedral morphology,while a higher percentage of metallic gold on the nanostructured cu_(2)O surface was mainly important for *** functional theory(DFT)calculations supported these findings,attributing the superior photoelectrocatalytic performance of the TNT@PDA/Nc/Au40%electrode for cH4generation to the formation of an OcH3intermediate bonded to Au *** using isotope-labeling and analysis by gas chromatograph-mass(Gc-MS)demonstrated that13cO_(2)was the source for photoelectrocatalytic generation of13cH3OH and13cH313cH2OH.

关键词： cu_(2)O nanocubes Photoelectrocatalysis Polydopamine cO_(2) photoelectroreduction DFT calculations

Rice Husk at a Glance:From Agro-industrial to Modern Applications

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Rice science 2024年第1期31卷 14-32页

作者： Masoumeh KORDi Naser FARROKHi Martin i.PEcH-cANUL Asadollah AHMADiKHAH Department of cell&Molecular Biology Faculty of Life Sciences and BiotechnologyShahid Beheshti UniversityTehran ***Iran 1062 Metallurgical industry Avenue Industrial Park Saltillo-Ramos ArizpeRamos ArizpeCoahuila 25900Mexico

Excessive waste production has led to the concept of a circular bioeconomy to deliver valuable by-products and improve environmental *** annual worldwide rice production accounts for more than 750 million tons of grain and 150 million tons of *** husk(RH)contains valuable biomaterials with extensive applications in various *** proportions of each component depend primarily on rice genotype,soil chemistry,and climatic *** and its derivatives,including ash,biochar,hydrochar,and activated carbon have been placed foreground of applications in agriculture and other *** the investigation on RH’s compositions,microstructures,and by-products has been done copiously,owing to its unique features,it is still an open-ended area with enormous scope for innovation,research,and ***,we reviewed the latest applications of RH and its derivatives,including fuel and other energy resources,construction materials,pharmacy,medicine,and nanobiotechnology to keep this versatile biomaterial in the spotlight.

关键词： circular bioeconomy rice husk activated carbon rice husk ash rice husk biochar rice husk hydrochar rice husk application

A Statistical Study of Magnetic Flux Emergence in Solar Active Regions Prior to Strongest Flares

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Research in Astronomy and Astrophysics 2024年第4期24卷 147-160页

作者： Alexander S.Kutsenko Valentina i.Abramenko Andrei A.Plotnikov crimean Astrophysical Observatory p/o NauchnyCrimea298409Russia

Using the data on magnetic field maps and continuum intensity for Solar cycles 23 and 24,we explored 100 active regions(ARs)that produced M5.0 or stronger *** focus on the presence/absence of the emergence of magnetic flux in these ARs 2-3 days before the strong flare *** found that 29 ARs in the sample emerged monotonically amidst quiet-Sun.A major emergence of a new magnetic flux within a pre-existing AR yielding the formation of a complex flare-productive configuration was observed in another 24 *** 30 ARs,an insignificant(in terms of the total magnetic flux of pre-existing AR)emergence of a new magnetic flux within the pre-existing magnetic configuration was observed;for some of them the emergence resulted in a formation of a configuration with a small δ-sunspot;11 out of 100 ARs exhibited no signatures of magnetic flux emergence during the entire interval of *** six cases the emergence was in progress when the AR appeared on the Eastern limb,so that the classification and timing of emergence were not *** conclude that the recent flux emergence is not a necessary and/or sufficient condition for strong flaring of an *** flux emergence rate of flare-productive ARs analyzed here was compared with that of flare-quiet ARs analyzed in our previous *** revealed that the flare-productive ARs tend to display faster emergence than the flare-quiet ones do.

关键词： Sun:activity Sun:flares Sun:magnetic fields

Radiative loss of coherence in free electrons:a long-range quantum phenomenon

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Light(Science & Applications) 2024年第2期13卷 294-301页

作者： cruz i.Velasco Valerio Di Giulio F.Javier García de Abajo icFO-institut de ciencies Fotoniques The Barcelona Institute of Science and Technology08860Castelldefels(Barcelona)Spain icREA-instituciócatalana de Recerca i Estudis Avançats Passeig Lluís Companys 2308010BarcelonaSpain

Quantum physics rules the dynamics of small objects as they interact over microscopic length ***,quantum correlations involving macroscopic distances can be observed between entangled photons as well as in atomic gases and matter waves at low *** long-range nature of the electromagnetic coupling between charged particles and extended objects could also trigger quantum phenomena over large ***,we reveal a manifestation of quantum mechanics that involves macroscopic distances and results in a nearly complete depletion of coherence associated with which-way free-electron interference produced by electron-radiation coupling in the presence of distant extended *** is a ubiquitous effect that we illustrate through a rigorous theoretical analysis of a two-path electron beam interacting with a semi-infinite metallic plate and find the inter-path coherence to vanish proportionally to the path separation at zero temperature and exponentially at finite *** investigated regime of large distances originates in the coupling of the electron to radiative modes assisted by diffraction at material structures but without any involvement of material *** the fundamental interest of this macroscopic quantum phenomenon,our results suggest an approach to measuring the vacuum temperature and nondestructively sensing the presence of distant objects.

关键词： temperature quantum macroscopic

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棉籽粕补饲对新疆细毛羊氮代谢的影响

西北农业学报 1999年第1期8卷 23-26页

作者：邓凯东 i.c.fletcher J.V.Nolan 新疆畜牧科学院中澳绵羊研究中心乌鲁木齐830000 澳大利亚新英格兰大学动物科学系

将24只约15月龄的新疆细毛母羊（平均体重28．9kg）随机分为6个处理组（每处理4只），以基础日粮作对照，混合精料日粮作标准，研究不同水平棉籽粕补饲的效果。结果表明，棉籽粕补饲显著提高了（P＜0．05）绵羊的总氮采食量、氮表观消... 详细信息

将24只约15月龄的新疆细毛母羊（平均体重28．9kg）随机分为6个处理组（每处理4只），以基础日粮作对照，混合精料日粮作标准，研究不同水平棉籽粕补饲的效果。结果表明，棉籽粕补饲显著提高了（P＜0．05）绵羊的总氮采食量、氮表观消化率、氮沉积、尿囊素排出量和由尿囊素排出量估测的瘤胃微生物氮产量。补饲棉籽粕绵羊的瘤胄微生物氮产量显著低于（P＜0．05）饲喂混合精料的绵羊，这可能与前者的能量采食量较低有关。

关键词：干草棉籽粕氮代谢新疆细毛羊细毛羊饲料

A facile strategy for tuning the density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications

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Bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： i.A.O.Beeren G.Dos Santos P.J.Dijkstra c.Mota J.Bauer H.Ferreira Rui L.Reis N.Neves S.camarero-Espinosa M.B.Baker L.Moroni Department of complex Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3B’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal icVS/3B’s-PT Government Associate Laboratory 4806-909 Braga/GuimarãesPortugal POLYMAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain iKERBASQUE Basque Foundation for Science48009 BilbaoSpain

Melt extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering ***,most synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell *** of biomolecules on polymeric surfaces of AM scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface ***,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(PcL5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight PcL75k at different *** porous three-dimensional(3D)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight PcL *** a proof-of-concept test,we prepared films of three different mass ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).Subsequently,a bone morphogenetic protein 2(BMP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal stromal cells(hMScs)was *** two weeks of culturing in a basic medium,cells expressed higher levels of BMP receptor ii(BMPRii)on films with the conjugated *** addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface *** together,these results emphasize that the density of surface peptides on cell differentiation must be considered at the cell-material ***,we have presented a viable strategy for ME-AM community that desires to tune the bulk and surface functionality via blending of(m

关键词： Additive manufacturing Blending Surface functionalization Surface density click chemistry Human