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Ri.k Fa.tors, Cli.i.a. Fea.ures, Ba.eli.e a.a.i.e a.i.otra.sfera.e a.d CD4⁺ Count of Chi.dren wi.h Hi. Co-i.fecti.n wi.h Hepa.i.i. B a.d C a. a.Terti.ry Hospi.a. i. Southwest Ni.eri.

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i.terna.i.na. Journa. of Cli.i.a. Medi.i.e 2016年第4期7卷 280-291页

作者： M. O. Durowa.e S. K. Ernest i. a. ojuawo Depa.tment of Pa.di.tri.s Federal Medical Centre Lokoja Nigeria Depa.tment of Pa.di.tri.s a.d Chi.d Hea.th University of Ilorin Ilorin Nigeria

Ba.kground: Huma. i.munodefi.i.ncy vi.us a.d hepa.i.i. B a.d C vi.uses a.e endemi. i. sub- Sa.a.a. a.ri.a. countri.s i.cludi.g Ni.eri.. Resea.chers ha.e studi.d the burden of co-i.fecti.n of Hi. wi.h hepa.i.i. B a.d hepa.i.i. C but the ri.k fa.tors a.d cli.i.a. presenta.i.n ha.e not been much a.dressed especi.lly i. chi.dren. Methodology: Thi. wa. a.prospecti.e cross secti.na. study tha. determi.ed the preva.ence, ri.k fa.tors, cli.i.a. fea.ures, ba.eli.e CD4+ count, CD4+ percenta.e, a.d a.a.i.e a.i.otra.sfera.e (a.T) of newly di.gnosed, Ha.RT na.ve Hi. co-i.fecti.n a.ong chi.dren who were ma.a.ed a. a.Terti.ry Hospi.a. i. i.ori., Ni.eri.. Result: Of the 60 Hi.- i.fected chi.dren recrui.ed, 11.7% ha. Hi. co-i.fecti.n wi.h HBV or HCV. Chi.dren wi.h co-i.fec- ti.ns (mea. a.e 8.43 ± 2.37 yea.s) were si.ni.i.a.tly older tha. thei. Hi. mono-i.fected counterpa.ts (mea. a.e 5.25 ± 3.96 yea.s) (p = 0.011). There wa. no si.ni.i.a.t di.ference between Hi. monoi.fecti.n a.d Hi. co-i.fecti.n wi.h respect to gender (p = 0.758), ethni.i.y (p = 0.707), reli.i.n of pa.ents (p = 0.436), fa.i.y type (p = 0.184), soci.l cla.s (p = 0.535), previ.us tra.sfusi.n (p = 0.053), sca.i.i.a.i.n (p = 0.612), fema.e geni.a. muti.a.i.n (p = 0.778), a.d sha.i.g of cli.pers (p = 0.806). The mea. BMi. i.munologi.a. sta.i.g (p = 0.535), ba.eli.e a.T (p = 0.940), a.d mea. ba.eli.e CD4+ count (p = 0.928) were compa.a.le. However, the body ma.s i.dex of Hi. co-i.fec- ted chi.dren decrea.ed wi.h a.e up ti.l a.e 10 yea.s. Conclusi.n: There were no ri.k fa.tors, nor cli.i.a. fea.ures predi.ti.e of co-i.fecti.n i.enti.i.d i. thi. study. Co-i.fecti.n di. not nega.i.ely i.pa.t ba.eli.e, CD4+ count a.d a.T.

关键词： Co-i.fecti.n Hepa.i.i. B Hepa.i.i. C Huma. i.munodefi.i.ncy Vi.us a.qui.ed i.munodefi.i.ncy Syndrome Hi. HBV HCV a.a.i.e a.i.otra.sfera.e a.T Hi.hly a.ti.e a.ti.etrovi.a. Thera.y Ha.RT Monoi.fecti.n CD4+ Ri.k Fa.tors for Co-i.fecti.n Tra.smi.si.n Hepa.i.i. B Surfa.e a.ti.en HBVsa.

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Hepa.i.i. C vi.us a.ti.odi.s a.ong tra.sfused chi.dren wi.h si.kle cell a.a.mi. a. Uni.ersi.y of i.ori. Tea.hi.g Hospi.a.

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Open Journa. of Pedi.tri.s 2013年第3期3卷 195-200页

作者： C. E. Onuchukwu a. ojuawo S. Kola.e Ernest Depa.tment of Pa.di.tri.s a.d Chi.d Hea.th Federal Medical Centre Keffi Nigeria Depa.tment of Pa.di.tri.s a.d Chi.d Hea.th University of Ilorin Teaching Hospital Ilorin Nigeria

Ba.kground: Hepa.i.i. C i. a. i.fecti.us di.ea.e of the li.er ca.sed by the Hepa.i.i. C vi.us (HCV) resulti.g to a.chroni. Hepa.i.i.. Chroni. HCV i.fecti.n consti.utes a.seri.us hea.th cha.lenge i. pla.es where preva.ence i. substa.ti.l. i. Ni.eri., there i. a.hi.h ri.k beca.se donor blood i. not routi.ely screened for HCV. Pa.i.nts wi.h si.kle cell a.a.mi. (SCa. a.e consi.ered a.subset of the popula.i.n a. hi.her ri.k of a.qui.i.g the vi.us, due to thei. frequent needs for tra.sfusi.n of blood a.d i.s products. However, the ma.ni.ude of HCV i.fecti.n ha. not been a.equa.ely mea.ured i. our genera. popula.i.n a.d speci.i. da.a.on HCV i. SCa.pa.i.nts a.e sca.ty, hence a.prospecti.e ca.e controlled study to determi.e the preva.ence of HCV a.ti.odi.s i. tra.sfused SCa.pa.i.nts a.tendi.g the si.kle cell a.a.mi. cli.i. i. the Uni.ersi.y of i.ori. Tea.hi.g Hospi.a. (Ui.H), i.ori. wa. ta.en. Objecti.e: To determi.e the preva.ence of Hepa.i.i. C vi.us a.ti.odi.s a.ong tra.sfused chi.dren wi.h SCa.i. i.ori.. Subjects a.d Method: Ei.hty two tra.sfused SCa.chi.dren a.ed 6 months to 14 yea.s were recrui.ed consecuti.ely from Februa.y 2008 to Ja.ua.y 2009 whi.e ei.hty four non tra.sfused SCa.chi.dren of the sa.e a.e ra.ge recrui.ed over the sa.e peri.d served a. controls. Hepa.i.i. C vi.us a.ti.ody screeni.g wa. done usi.g a.second genera.i.n ELi.a.method. Results: The overa.l preva.ence of HCV a.ti.ody wa. 3.0%, whi.e i. wa. 3.7% a.d 2.4% i. the tra.sfused a.d non tra.sfused SCa.pa.i.nts respecti.ely (χ2 = 0.23, p = 0.68). The pa.i.nts were a.so compa.a.le a.ross the soci.l cla.s when subca.egori.ed i.to hi.h a.d low soci.l cla.s (χ2 = 0.37, p = 1.00 (subjects), χ2 = 0.42, p = 1.00 (controls). Conclusi.n: The preva.ence of Hepa.i.i. C vi.us a.ti. bodi.s i. tra.sfused SCa.pa.i.nts i. low. The di.ference i. preva.ence between tra.sfused a.d nontra.sfused SCa.pa.i.nt wa. not sta.i.ti.a.ly si.ni.i.a.t. Thi. wa. ca.ti.usly i.terpreted due to the hospi.a. ba.ed premi.e of the work. T

关键词： Hepa.i.i. C Vi.us Si.kle Cell a.a.mi. Blood Tra.sfusi.n

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a.soci.ti.n between i.testi.a. Helmi.thi.si. a.d Serum Ferri.i. Levels a.ong School Chi.dren

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Open Journa. of Pedi.tri.s 2011年第2期1卷 12-16页

作者： Olufunmi.a.o Vi.tori. a.eba.a.Sa.uel Kola.e Ernest i.a.c a.odele ojuawo 不详

Ba.kground: Si.ni.i.a.t i.on defi.i.ncy a.a.mi. i. a.ma.or concern i. chi.dren wi.h helmi.thi.si., beca.se i. ma. eventua.ly contri.ute to the growi.g hea.th cha.lenges of severe a.a.mi. Thi. descri.ti.e cross secti.na. study wa. ca.ri.d out to determi.e the a.soci.ti.n between serum ferri.i. levels a.d i.testi.a. helmi.thi.si. a.ong school chi.dren. Methods: a.structured questi.nna.0}e wa. used to collect the study popula.i.n da.a. Stool speci.ens were obta.0}ed a.d exa.i.ed on the sa.e da. usi.g the sedi.enta.i.n method for i.enti.i.a.i.n of the pa.a.i.e. Blood sa.ples were a.so obta.0}ed for full blood count a.d serum ferri.i. mea.urement. Results: a.tota. of 246 school chi.dren were studi.d wi.h a.response ra.e of 82%. The preva.ence of i.testi.a. helmi.thi.si. wa. 29.7%. The di.ferent helmi.thes i.enti.i.d i.cluded a.ca.i. lumbri.oi.es, Neca.or a.eri.a.us, Tri.huri. tri.hi.ra. Strongyloi.es stercora.i.. Of the popula.i.n studi.d, 36.2% were a.a.mi., 15.9% ha. mi.rocytosi., a.d 47.6% ha. hypochromi.. The preva.ence of ex-ha.sted i.on stores wa. 3.7%. Serum ferri.i. levels were si.ni.i.a.tly lower i. chi.dren wi.h i.testi.a. helmi.thi.si. compa.ed wi.h controls. Conclusi.ns: The fi.di.gs i. thi. study demonstra.e a. i.verse re-la.i.nshi. between i.testi.a. helmi.thi.si. a.d serum ferri.i. levels a.d thi. i. more ma.ked i. pupi.s wi.h hookworm i.fecti.ns. The control of i.testi.a. hel-mi.thi.si. a.d preventi.n of i.on defi.i.ncy a.a.mi. should be gi.en hi.h pri.ri.y i. the i.plementa.i.n of the school hea.th progra.me.

关键词： i.testi.a. helmi.thi.si. serum ferri.i. school chi.dren

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Ma.a.ement of Opi.i. Use Di.order i. Si.kle Cell a.a.mi. a.i.st Growi.g Mena.e i. the Genera. Popula.i.n

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Open Journa. of Pedi.tri.s 2023年第6期13卷 807-820页

作者： a.i.bola.a.oluwa.i. a.obola.ojuawo Oluwa.obi.a.a.bi.La.eef Qua.ri.Ha.na. Elukpo a.eba.o Oloko Kola.e Ernest Pa.di.tri. Ha.ma.ology Uni. Department of Paediatrics University of Ilorin Teaching Hospital Ilorin Nigeria i.sti.ute of Medi.a. Resea.ch a.d Tra.0}i.g University of Ilorin Ilorin Nigeria

Ni.eri. ha. a.very hi.h number of si.kle cell di.ea.e (SCD) popula.i.n wi.h a.di.i.n of 150,000 ba.i.s born a.nua.ly wi.h the di.ea.e. Ea.ly i.fa.t di.gnosi. a.d good ca.e ma.e ma.y of these ba.i.s survi.e to a.ulthood. Severe pa.0} requi.i.g modera.ely strong or very strong a.a.gesi.s i. a.common presenta.i.n of pa.i.nts wi.h Si.kle Cell a.a.mi.. Pa.di.tri.i.ns fi.d rea.y usefulness of Opi.i.s whi.h a.e very useful for the pa.0}ful epi.odes a.ong these pa.i.nts. Therefore, the cha.ces of a.use a.d a.di.ti.n to these medi.a.i.ns become very hi.h a.d consti.ute a.di.i.na. burden on the defi.i.nt ma.power i. the hea.th sector. Opi.i. Use Di.order a.ong Si.kle Cell Di.ea.e pa.i.nts ha. subtle presenta.i.n, so a.hi.h i.dex of suspi.i.n i. requi.ed to ma.e both the di.gnosi. a.d referra. to trea.ment centres. i. thi. revi.w, the epi.emi.logy, pa.0} pa.hophysi.logy, beha.i.ura. a.d pha.ma.ologi. thera.y ha.e been re-exa.i.ed.

关键词： Si.kle Cell Di.ea.e Opi.i. Use Di.order Globa. Mena.e Trea.ment Centres True a.di.ti.n a.d Pseudo-a.di.ti.n

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Serum Zi.c, Copper a.d a.bumi. i. Pa.0}ed Mothers a.d Thei. Term Newborn i. a.Terti.ry Hospi.a. i. Ni.eri.

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Open Journa. of Pedi.tri.s 2018年第3期8卷 273-282页

作者： a.odele ojuawo a.1}ha. Sa.a.Omota.o a.esi.un Tope Oba.a.Bunmi.Ola.i.oye Ki.e a.esi.a.a.a.omi.Bi.i.mi.u a.edeji.a.eri.i.be Musi.a. a.ula.eez Depa.tment of Pa.di.tri.s Obstetrics & Gynaecology Chemical Pathology Epidemiology & Community Health University of Ilorin Teaching Hospital Ilorin Nigeria

Objecti.e: Thi. study a.sessed the serum zi.c, copper a.d a.bumi. levels i. pa.0}ed mother a.d newborns i. the i.medi.te neona.a. peri.d to esta.li.h the rela.i.nshi. between the pa.0}, a.d the i.fluence of ma.erna. mi.ronutri.nt sta.us on tha. of the newborn i. a.y. Methods: The soci.demogra.hi. cha.a.teri.ti.s of the mothers were obta.0}ed usi.g a.structured questi.ner a.ter i.formed consent wa. obta.0}ed from the pa.ents of the ba.y. a. deli.ery, pa.0}ed mother a.d newborns ha. thei. serum zi.c, copper a.d a.bumi. a.sa.ed, usi.g cord blood i. the newborn. Result: One hundred a.d thi.ty fi.e mothers a.d thei. pa.0}ed term newborns completed the study. The mea. a.e of the mothers wa. 29.2 ± 4.6 yea.s wi.h 67% wi.hi. the a.e bra.ket 20 to 30 yea.s. Seventy three percent of the mothers a.ta.0}ed terti.ry educa.i.n a.d 22% ha. seconda.y educa.i.n. The mea. serum zi.c wa. si.ni.i.a.tly hi.her i. the newborn (3.67 ± 1.49 μmol/L) tha. i. the mothers (2.20 ± 1.01 μmol/L), p = 0.0001, wi.h a.feto-ma.erna. ra.i. of 1.6 to 1. Copper wa. si.ni.i.a.tly hi.her i. the mothers (4.27 ± 1.77 μmol/L), tha. i. the newborns (2.84 ± 0.92 μmol/L) (p = 0.001), wi.h a.ma.erna.-feta. ra.i. of 1.5 to 1. Mea. serum a.bumi. wa. si.ni.i.a.tly lower i. the newborns tha. i. the mothers (p > 0.011). Conclusi.n: Thi. study esta.li.hed tha. term newborns ha.e hi.her serum zi.c, a.lower serum copper a.d a.bumi. levels tha. thei. ma.erna. levels. The di.tri.uti.n of these tra.e elements i. proba.ly protecti.e i. the newborns a.a.0}st i.fecti.n.

关键词： Ma.erna.-Newborn Pa.0} Zi.c Copper a.bumi.

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