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Radio Frequency Tank Circuit for Probing Planar Lipid Bilayers

Soft Nanoscience Letters 2013年第4期3卷 87-92页

作者： Abhishek Bhat Jonathan Rodriguez Hua Qin Hyun Cheol shin hyuncheol shin Joerg Clobes Dustin Kreft Jonghoo Park Eric Stava Minrui Yu Robert H. Blick Electrical Engineering Kyungpook National University Daegu Republic of Korea Genome Center of Wisconsin University of Wisconsin-Madison Madison USA. Laboratory for Molecular-Scale Engineering Department of Electrical and Computer Engineering University of Wisconsin-Madi- son Madison USA Laboratory for Molecular-Scale Engineering Department of Electrical and Computer Engineering University of Wisconsin-Madi- son Madison USA Laboratory of Nanodevices and Application Suzhou Institute of Nanotech and Nanobionics Chinese Academy of Sciences Beijing China

We present first results from a hybrid coplanar waveguide microfluidic tank circuit for monitoring lipid bilayer formation and fluctuations of integrated proteins. The coplanar waveguide is a radio frequency resonator operating at ~250 MHz. Changes within the integrated microfluidic chamber, such as vesicle bursting and subsequent nanopore formation alter the reflected signal, and can be detected with nanosecond resolution. We show experimental evidence of such alterations when the microfluidic channel is filled with giant unilamellar vesicles (GUVs). Subsequent settling and bursting of the GUVs form planar lipid bilayers, yielding a detectable change in the resonant frequency of the device. Results from finite element simulations of our device correlate well with our experimental evidence. These simulations also indicate that nanopore formation within the bilayer is easily detectable. The simulated structure allows for incorporation of microfluidics as well as simultaneous RF and DC recordings. The technique holds promise for high throughput drug screening applications and could also be used as an in-plane probe for various other applications. It opens up possibilities of exploring ion channels and other nano scale pores in a whole new frequency band allowing for operating at bandwidths well above the traditional DC methods.

关键词： Radio Frequency Simulations Lipid Bilayers Ion Channels High Speed Planar Detection

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Multi-directionally wrinkle-able textile OLEDs for clothing-type displays

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npj Flexible Electronics 2020年第1期4卷 288-296页

作者： Seungyeop Choi Woosung Jo Yongmin Jeon Seonil Kwon Jeong Hyun Kwon Young Hyun Son Junmo Kim Jun Hong Park hyuncheol Kim Ho Seung Lee Minwoo Nam Eun Gyo Jeong Jeong Bin shin Taek-Soo Kim Kyung Cheol Choi School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea

A clothing-type wearable display can be utilized in fashion,bio-healthcare,and safety industries as well as smart textiles for the internet of things(IoTs)and wearable *** response to this trend,we demonstrate a textile display that can endure the active movements of a human *** can be applied to any kind of textile,and is durable against conditions such as rain,sweat,and *** a key technology for realizing the multi-directional wrinkle-able textile display,we fabricated a stress-lowering textile platform with an ultrathin planarization layer replicated from the flat surface of *** elastomeric strain buffer for reducing mechanical stress is also inserted into the textile ***,organic light-emitting diodes(OLEDs)with red,green and blue color,thin film transistors(TFTs)fabricated at a low temperature below 150℃,and a washable encapsulation layer blocking both gas and liquid were demonstrated on the textile platform.

关键词： OLEDs IoT directional

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