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Limited endoscopic sphincterotomy plus large balloon dilation for choledocholithiasis with periampullary diverticula

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World Journal of Gastroenterology 2010年第34期16卷 4335-4340页

作者： Hyung Wook Kim Dae hwan Kang Cheol Woong choi Jong hwan Park Jin Ho Lee Min Dae Kim Il Doo Kim Ki Tae Yoon Mong Cho Ung Bae Jeon Suk Kim Chang Won Kim jun Woo Lee Department of Internal Medicine Pusan National University School of Medicine and Medical Research Institute Pusan National University Yangsan Hospital Department of Radiology Pusan National University School of Medicine and Medical Research Institute Pusan National University Hospital

AIM: To investigate the effectiveness and safety of limited endoscopic sphincterotomy (EST) plus large balloon dilation (LBD) for removing choledocholithiasis in patients with periampullary diverticula (PAD). METHODS: A total of 139 patients with common bile duct (CBD) stones were treated with LBD (10-20 mm balloon diameter) after limited EST. Of this total, 73 patients had PAD and 66 patients did not have PAD (controls). The results of stone removal and complications were retrospectively evaluated. RESULTS: There were no significant differences between the PAD and the control groups in overall successful stone removal (94.5% vs 93.9%), stone removal in first session (69.9% vs 81.8%), mechanical lithotripsy (12.3% vs 13.6%), and complications (11.0% vs 7.6%). Clinical outcomes were also similar between the types of PAD, but the rate of stone removal in first session and the number of sessions were significantly lower and more frequent, respectively, in type B PAD (papilla located near the diverticulum) than controls [23/38 (60.5%) vs 54/66 (81.8%), P = 0.021; and 1 (1-2) vs 1 (1-3), P = 0.037, respectively] and the frequency of pancreatitis was significantly higher in type A PAD (papilla located inside or in the margin of the diverticulum) than in controls (16.1% vs 3.0%, P = 0.047). CONCLUSION: Limited EST plus LBD was an effective and safe procedure for removing choledocholithiasis in patients with PAD. However, some types of PAD should be managed with caution.

关键词： Endoscopic sphincterotomy Large balloon dilation Choledocholithiasis Periampullary diverticula

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High-throughput compositional mapping of triple-cation tin-lead perovskites for high-efficiency solar cells

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InfoMat 2023年第4期5卷 25-38页

作者： Rajendra Kumar Gunasekaran Jina jung Sung Woong Yang jungchul Yun Yeonghun Yun Devthade Vidyasagar Won Chang choi Chang-Lyoul Lee jun Hong Noh Dong Hoe Kim Sangwook Lee School of Materials Science and Engineering Kyungpook National UniversityDaeguRepublic of Korea Advanced Photonics Research Institute(APRI) Gwangju Institute of Science and Technology(GIST)GwangjuRepublic of Korea School of Civil Environmental and Architectural EngineeringGreen SchoolKorea UniversitySeoulRepublic of Korea Department of Materials Science and Engineering Korea UniversitySeoulRepublic of Korea

Mixed tin-ead perovskites suffer from structural instability and rapid tin oxidation;thus,the investigation of their optimal composition ranges is important to address these inherent *** critical role of triple cations in mixed Sn–Pb iodides is studied by performing a wide range of compositional screenings over mechanochemically synthesized bulk and solution-processed thin films.A ternary phase map of FA(Sn_(0.6)Pb_(0.4))I_(3),MA(Sn_(0.6)Pb_(0.4))I_(3),and Cs(Sn_(0.6)Pb_(0.4))I_(3)is formed,and a promising composition window of(FA_(0.6-x)MA_(0.4)Cs_(x))Sn_(0.6)Pb_(0.4)I_(3)(0≤x≤0.1)is demonstrated through phase,photoluminescence,and stability *** cell performance and chemical stability across the targeted compositional space are investigated,and FA_(0.55)MA_(0.4)Cs_(0.05)Sn_(0.6)Pb_(0.4)I_(3)with strain-relaxed lattices,reduced defect densities,and improved oxidation stability is *** inverted perovskite solar cells with the optimal composition demonstrate a power conversion efficiency of over 22%with an open-circuit voltage of 0.867 V,which corresponds to voltage loss of 0.363 V,promising for the development of narrow-bandgap perovskite solar cells.

关键词： compositional engineering mixed tin-ead iodides narrow-bandgap perovskites perovskite solar cells strain relaxation ternary phase mapping

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Rapid Preparation of Monolithic Columns for Capillary Electrochromatography Separation

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Chinese Chemical Letters 2006年第6期17卷 813-816页

作者： Wen jun GONG Yi jun ZHANG Yu Ping ZHANG Seong Ho choi Henan Institute of Science and Technology Xinxiang 453003 Department of Chemistry Hannam University Daejon South Korea

Fritless packed silica gel columns were prepared using sol-gel technology, The part of a 75 μm i.d. capillary was filled with a mixture of methacryloxypropyltrimethoxysilane, toluene and hydrochloric acid. Four different photoinitiators such as benzoin methyl ether, Irgacure 819, Irgacure 1700 and Irgacure 1800 were added in the presence or absence of sodium dodecyl sulfate during the polymerization process. The above eight solutions were irradiated at 365 nm about 5-10 min to prepare the porous monolithic sol-gel columns by a one-step process.

关键词： Monolithic columns electrochromatography photopolymerized sol-gel.

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Suppressing surface plasmon losses to improve the efficiency of blue organic light-emitting diodes using the plasmonic quasi-bandgap phenomenon

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Photonics Research 2021年第9期9卷 1784-1795页

作者： TAE-WOO LEE DOHONG KIM jun HEE HAN SOMIN LEE HOSEUNG LEE SEUNGYEOP choi KYUNG CHEOL choi School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea

It is a persistent problem in organic light-emitting diode(OLED)display devices that the efficiency of blue-light source materials is lower than that of green-or red-light source *** address this problem,numerous studies have investigated blue-light-emitting ***,ensuring the reliability of the blue-light-emitting materials has been difficult in most *** this study,electrodes using asymmetric dielectric/metal/dielectric structures with plasmonic quasi-bandgap characteristics were developed to achieve a highly efficient blue fluorescent *** electrodes were applied in a microcavity OLED and a transparent *** the developed electrode in fabricated OLED devices not only maximized the cavity resonance effect and transparency,but also preserved the advantage of the work function of the metal in terms of electrical properties,with high device *** approach also minimized losses caused by surface plasmon polaritons,which is a blind spot in the optical aspect of metal electrodes,resulting in improved light extraction efficiency.

关键词： light blue surface

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Weave-pattern-dependent fabric piezoelectric pressure sensors based on polyvinylidene fluoride nanofibers electrospun with 50 nozzles

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npj Flexible Electronics 2022年第1期6卷 699-707页

作者： Da Bin Kim Ju Han Sun Min Sung Min Seong Kim Bo Kyoung choi Sung jun Park Hyae Rim Hong Hong Je choi Byeong Kon Kim Chung Hee Park Jong Hoo Paik Joon-Seok Lee Yong Soo Cho Department of Materials Science and Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Textile Engineering and Technology Yeungnam UniversityGyeongsan 38541Republic of Korea Deparment of Textile Merchandising and Fashion DesignSeoul National UniversitySeoul 08826Republic of Korea Samsung Electro-Mechanics Co.Ltd. Suwon 16674Republic of Korea Ceratorq Inc. Seoul 08511Republic of Korea Electronic Materials and Component Center Korea Institute of Ceramic Engineering and TechnologyJinju 52851Republic of Korea

Wearable pressure sensors having versatile device structures have been extensively investigated to achieve high sensitivity under mechanical ***,we introduce piezoelectric pressure sensors based on fabrics woven using polyvinylidene fluoride(PVDF)weft and polyethylene terephthalate(PET)warp yarns with different weave structures:1/1(plain),2/2,and 3/3 weft rib *** dependence of the pressure-sensing performance on the weave pattern is demonstrated with an actual large-scale fabric up to the~2 m *** optimized pressure sensor with a 2/2 weft rib pattern produced a high sensitivity of 83 mV N−1,which was 245%higher than that of the 1/1 *** detection performance of the optimal fabric was extensively evaluated with a variety of ambient input sources,such as pressing,bending,twisting,and crumpling,as well as various human ***,a large allfabric pressure sensor with arrayed touch pixel units demonstrated highly sensitive and stable sensing performance.

关键词： pattern fluoride piezoelectric

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用于电化学能量转换反应的非贵金属单原子催化剂

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Chinese Journal of Catalysis 2023年第7期50卷 195-214页

作者： Sang Eon jun Sungkyun choi Jaehyun Kim Ki Chang Kwon Sun Hwa Park Ho Won Jang 首尔国立大学先进材料研究所材料科学与工程系首尔韩国韩国标准与科学研究院跨学科材料测量研究所大田韩国首尔国立大学融合技术高级研究所水原韩国

非贵金属单原子催化剂(NNMSAC)被认为是贵金属单原子催化剂的经济替代品,同时保留了源自单原子位点独特电子结构的高催化活性.通过金属-载体充分的相互作用,NNMSAC可以在各种电催化反应中发挥关键作用,具有与贵金属单原子催化剂相当的... 详细信息

非贵金属单原子催化剂(NNMSAC)被认为是贵金属单原子催化剂的经济替代品,同时保留了源自单原子位点独特电子结构的高催化活性.通过金属-载体充分的相互作用,NNMSAC可以在各种电催化反应中发挥关键作用,具有与贵金属单原子催化剂相当的高原子利用效率和选择性.为此,本文首先综述了NNMSAC在调节反应选择性、金属-载体相互作用和催化活性中心方面的特点.随后,详细介绍了用于析氢反应、析氧反应、氧还原反应、二氧化碳还原反应和氮还原反应的代表性NNMSAC(Co,Ni,Fe,Cu和双金属SAC)催化剂.最后,展望了NNMSAC在几何、电子和电化学性能方面进一步发展所面临的挑战.

关键词：单原子催化剂非贵金属电催化水裂解 CO_(2)还原

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Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie＇s plaque

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Asian Journal of Andrology 2015年第3期17卷 487-492页

作者： Min Ji choi Kang-Moon Song Jin-Mi Park Mi-Hye Kwon Ki-Dong Kwon Soo-hwan Park Dong-Soo Ryu Ji-Kan Ryu jun-Kyu Suh Department of Urology National Research Center for Sexual Medicine Inha University School of Medicine Incheon 400-711 Korea Department of Urology Changwon Samsung Medical Center Changwon 630-522 Korea Inha Research Institute for Medical Sciences Inha University School of Medicine Incheon 400-711 Korea

Transforming growth factor-β1 （TGF-β1） has been identified as one of the most important fibrogenic cytokines associated with Peyronie＇s disease （PD）. The mothers against decapentaplegic homolog 7 （SMAD7） is an inhibitory Smad protein that blocks TGF-J3 signaling pathway. The aim of this study was to examine the anti-fibrotic effect of the SMAD7 gene in primary fibroblasts derived from human PD plaques. PD fibroblasts were pretreated with the SMAD7 gene and then stimulated with TGF-β1. Treated fibroblasts were used for Western blotting, fluorescent immunocytochemistry, hydroxyproline determination, and terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling assays. Overexpression of the SMAD7 gene inhibited TGF-β1-induced phosphorylation and nuclear translocation of SMAD2 and SMAD3, transdifferentiation of fibroblasts into myofibroblasts, and quashed TGF-β1-induced production of extracellular matrix protein and hydroxyproline. Overexpression of the SMAD7 gene decreased the expression of cyclin D1 （a positive cell cycle regulator） and induced the expression of poly （ADP-ribose） polymerase 1, which is known to terminate Smad-mediated transcription, in PD fibroblasts. These findings suggest that the blocking of the TGF-β pathway by use of SMAD7 may be a promising therapeutic strategy for the treatment of PD.

关键词： cell culture decapentaplegic homolog 7 fibrosis Peyronie's disease transforming growth factor-beta

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High-resolution circulation forecasting of the Maenggol Channel, south coast of Korea

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Acta Oceanologica Sinica 2015年第12期34卷 11-18页

作者： choi Jinyong jun Kicheon choi Youngkwang CHO Kyoungho KWON Jae-Il PARK Jinsoon PARK Kwangsoon Operational Oceanography Research Center Korea Institute of Ocean Science and Technology Task Force for Construction of RV ISABU Support Facility Korea Institute of Ocean Science and Technology Division of Polar Ocean Environment Korea Polar Research Institute China-Korea Joint Ocean Research Center Coastal Development Research Center Korea Institute of Ocean Science and Technology

The Maenggol Channel and Uldolmok Strait, located on the south-west coast of Korea, have notably strong and complex currents due to tidal effects and to local geological factors. In these areas, electric power has been generated using strong tidal currents, the speed of which is more than 3 m/s during spring tides. The region also provides a shortcut for navigation. These tidal conditions are therefore sometimes useful, but may also cause terrible accidents or severe economic damage, in the absence of accurate information regarding ocean conditions. In April 2014, the passenger ferry MV Sewol capsized in the Maenggol Channel, with 295 passengers killed and 9 still missing. While this was unquestionably a man-made disaster, strong currents were one of the contributing causes. It was also difficult to conduct scuba diving rescue operations given strong current speeds,and accurate prediction of the time when the tide would turn was thus critically needed. In this research, we used the high-resolution coastal circulation forecasting system of KOOS（Korea Operational Oceanographic System） for analysis and simulation of strong tidal currents in such areas with many small islands, using measurements and modeling from this research area. For accurate prediction of tidal currents, small grid size-modeling was needed,and in this study, we identified a suitable grid size that offers efficiency as well as accuracy.

关键词： Maenggol Channel Sewol ferry accident circulation forecasting

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Feedback Control of an Achiral Robotic Microswimmer

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Journal of Bionic Engineering 2017年第2期14卷 245-259页

作者： U Kei Cheang Hoyeon Kim Dejan Milutinovic Jongeun choi Min jun Kim Department of Mechanical Engineering and Mechanics Drexel University Philadelphia PA 19104 USA Department of Mechanical Engineering Southern Methodist University Dallas TX75275 USA Department of Computer Engineering University of California Santa Cruz Santa Cruz California 95064 USA School of Mechanical Engineering Yonsei University Seoul South Korea

Magnetic microswimmers are useful for navigating and performing tasks at small scales. To demonstrate effective control over such microswimmers, we implemented feedback control of the three-bead achiral microswimmers in both simulation and experiment. The achiral microswimmers with the ability to swim in bulk fluid are controlled wirelessly using magnetic fields generated from electromagnetic coils. The achirality of the microswimmers introduces unknown handedness resulting in uncertainty in swimming direction. We use a combination of rotating and static magnetic fields generated from an approximate Helmholtz coil system to overcome such uncertainty. There are also movement uncertainties due to environmental factors such as unsteady flow conditions. A kinematic model based feedback controller was created based on data fitting of experimental data. However, the controller was unable to yield satisfactory performance due to uncertainties from environmental factors; i.e., the time to reach target pose under adverse flow condition is too long. Following the implementation of an integral controller to control the microswimmers＇ swimming velocity, the mieroswimmers were able to reach the target in roughly half the time. Through simulation and experiments, we show that the feedback control law can move an achiral microswimmer from any initial conditions to a target pose.

关键词： microrobotics magnetic control low Reynold number chirality feedback control

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Glucose-responsive artificial promoter-mediated insulin gene transfer improves glucose control in diabetic mice

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World Journal of Gastroenterology 2012年第44期18卷 6420-6426页

作者： Jaeseok Han Eung-Hwi Kim Woohyuk choi Hee-Sook jun Department of Microbiology and Infectious Diseases University of Calgary3330 Hospital Drive N.W.CalgaryAlberta T2N 4N1Canada Del E.Webb Neuroscience Aging and Stem Cell Research CenterSanford Burnham Medical Research InstituteLa JollaCA 92037United States Lee Gil Ya Cancer and Diabetes Institute Gachon University7-45 SondodongYeonsu-kuIncheon 406-840South Korea College of Pharmacy Gachon University7-45 Sondo-dongYeonsu-kuIncheon 406-840South Korea

AIM:To investigate the effect of insulin gene therapy using a glucose-responsive synthetic promoter in type 2 diabetic obese ***:We employed a recently developed novel insulin gene therapy strategy using a synthetic promoter that regulates insulin gene expression in the liver in response to blood glucose level *** intravenously administered a recombinant adenovirus expressing furin-cleavable rat insulin under the control of the synthetic promoter(rAd-SP-rINSfur) into diabetic Lepr db/db mice.A recombinant adenovirus expressing β-galactosidase under the cytomegalovirus promoter was used as a control(rAd-CMV-βgal).Blood glucose levels and body weights were monitored for 50 *** and insulin tolerance tests were *** staining was performed to investigate islet morphology and insulin ***:Administration of rAd-SP-rINSfur lowered blood glucose levels and normoglycemia was maintained for 50 d,whereas the rAd-CMV-βgal control virus-injected mice remained *** tolerance tests showed that rAd-SP-rINSfur-treated mice cleared exogenous glucose from the blood more efficiently than control virus-injected mice at 4 wk [area under the curve(AUC):21 508.80 ± 2248.18 vs 62 640.00 ± 5014.28,P < 0.01] and at 6 wk(AUC:29 956.60 ± 1757.33 vs 60 016.60 ± 3794.47,P < 0.01).In addition,insulin sensitivity was also significantly improved in mice treated with rAd-SP-rINSfur compared with rAd-CMV-βgal-treated mice(AUC:9150.17 ± 1007.78 vs 11 994.20 ± 474.40,P < 0.05).The islets from rAd-SP-rINSfur-injected mice appeared to be smaller and to contain a higher concentration of insulin than those from rAd-CMV-βgal-injected ***:Based on these results,we suggest that insulin gene therapy might be one therapeutic option for remission of type 2 diabetes.

关键词：胰岛素基因 2型糖尿病血糖水平启动子葡萄糖敏感性小鼠控制

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