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Computer Systems Science & Engineering 2024年第5期48卷 1113-1131页

作者： Zakir hussain Ahmed Maha Ata Al-Furhood Abdul Khader Jilani Saudagar Shakir Khan Department of Mathematics and Statistics College of ScienceImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia Department of Computer Science College of Computer and Information SciencesJouf UniversitySakakah42421Saudi Arabia Information Systems Department Imam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia College of Computer and Information Sciences Imam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia

The generalized travelling salesman problem(GTSP),a generalization of the well-known travelling salesman problem(TSP),is considered for our *** the GTSP is NP-hard and very complex,finding exact solutions is highly expensive,we will develop genetic algorithms(GAs)to obtain heuristic solutions to the *** GAs,as the crossover is a very important process,the crossovermethods proposed for the traditional TSP could be adapted for the *** sequential constructive crossover(SCX)and three other operators are adapted to use in GAs to solve the *** effectiveness of GA using SCX is verified on some GTSP Library(GTSPLIB)instances first and then compared against GAs using the other crossover *** computational results show the success of the GA using SCX for this *** proposed GA using SCX,and swap mutation could find average solutions whose average percentage of excesses fromthe best-known solutions is between 0.00 and 14.07 for our investigated instances.

关键词： Generalized travelling salesman problem NP-hard genetic algorithms sequential constructive crossover swap mutation

Radiographic Equipment and Accessories as a Potential Source of Nosocomial Infection

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Open Journal of Radiology 2024年第3期14卷 147-155页

作者： Lina Fahmi Hammad Essam hussain Mattar Hanadi Talal Ahmedah Mohamed Zain Shamweel Ahmad Hiba Shamweel Radiological Sciences Department College of Applied Medical Sciences King Saud University Riyadh KSA Department of Medical Laboratory Technology Faculty of Applied Medical Sciences King Abdulaziz University Rabegh KSA Botany and Microbiology Department College of Science King Saud University Riyadh KSA Department of Medical Laboratory Sciences College of Medical Sciences Prince Sattam Bin Abdulaziz University Al Kharj KSA Al-Haram Diagnostic Research and Training Center Srinagar Kashmir

Background: Nosocomial infections have become a major challenge in healthcare facilities as they affect the quality of medical care. Radiological imaging plays a crucial role in medical diagnosis. However, the equipment and accessories used increase the risk of transmission of nosocomial bacteria. Objective: This study aims to reveal the extent and nature of microbiological contamination in four hospital diagnostic imaging departments to determine their potential role in the spread of nosocomial bacteria and to evaluate the effectiveness of routine daily disinfection practices in controlling microorganisms in diagnostic imaging departments. Methods & Results: In each department, swabs were taken from the surfaces of selected parts of the equipment and accessories three times a day (early morning, noon, and evening) for five consecutive days. Bacteria were isolated from 65 swabs (36.1% of all samples). The bacteria were isolated 3 times (4.6%) in the morning, 16 times (24.6%) at midday, and 46 times (70.7%) in the evening. The bacteria isolated were Escherichia coli (isolated 34 times;52.3%), Staphylococcus aureus (20 times;30.8%), Staphylococcus epidermidis (6 times;9.3%), and Klebsiella species (5 times;7.7%). Discussion & Conclusion: Findings demonstrated that radiology equipment and accessories are not free of bacteria and further improvements in the sterilization and disinfection of radiology equipment and accessories are needed to protect staff and patients from nosocomial infections.

关键词： Diagnostic Imaging Department Nosocomial Infection Radiographic Accessories Radiographic Equipment

Use of Topical Complementary and Alternative Medicines (CAM) in Diabetic Septic Foot Disease in Makkah Region, Western of Saudi Arabia, an Exploratory Study

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Journal of Biosciences and Medicines 2024年第3期12卷 245-258页

作者： Mohamed Elamin Salih Hatim Alrizqi Mohammed hussain Abdullah Alshumrani Ismail Alhasani Ali Alkhamisi Hamzah Alsayed Fahad Alqarni Department of Surgery Faculty of Medicine University of Umm AlQura Mecca Saudi Arabia Faculty of Medicine University of Umm AlQura Mecca Saudi Arabia

Diabetes is a chronic condition that is significantly impacted daily by environment. At least one in five Saudis, suffer from diabetes. “Diabetes is a pandemic of unprecedented magnitude spiraling out of control” (Boulton). Saudi Arabia ranks the second highest in the Middle East, and is the seventh in the world for the prevalence of diabetes (WHO). Diabetes mellitus (DM) has been found to be related to high mortality, morbidity accompanied by poor general health and lower quality of life. Current Saudi diabetes patients’ behaviors, practices, and beliefs regarding foot health problems such as ulcers, are not well investigated. Diabetic patients frequently utilize natural remedies and Herbs for self-medication as a part of complementary and alternative Medicine. Aim of study: To explore the widespread use of the alternative remedies in the local communities of the Western Saudi Arabia, the drives behind using and to focus on the potential adverse effects following their usage. Method: A descriptive, cross-sectional study of 386 diabetic patients with feet problems in Makkah Region, West of Saudi Arabia during the period April - June 2023. Results: Out of the 531 participants, only 386 participants reported diabetic foot disorder (DFD). Most of the participant were above 65 years of age group (24.61 %). Male (52.08%) more than female (47.92%) in the research group. All of the participants had diabetic foot disorders at least once. The prevalence of complementary and alternative medicines (CAM) use among them was 67.88%, as solitary or in combination with hospital medicines. Honey headed the list followed by myrrh and black seeds. Acquaintances advice (59.54%) was the most reason for using the alternative medicine. 60.30% of Diabetic foot patient complained of adverse effects during CAM remedies use. Conclusion: Consumption of CAM remedies among diabetic patients for Diabetic Foot Disorder (DFD) is common. Honey headed the list followed by myrrh and black seeds. Addit

关键词： Diabetic Foot Ulcer Diabetes Complementary and Alternative Medicine CAM West of Saudi Arabia

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芸薹根肿菌生理小种鉴定与检测方法研究进展

微生物学通报 2024年第9期51卷 3348-3371页

作者：余红瑞章艺张舒晴 hussain Iqbal 董正中雷娜门万杰余小林浙江大学蔬菜研究所浙江杭州310058 浙江大学新农村发展研究院浙江杭州310058 哈尔滨市农业科学院黑龙江哈尔滨150086

根肿病是由芸薹根肿菌(Plasmodiophora brassicae Woronin)引起的全球性土传病害,对十字花科芸薹属作物的产量和质量构成了严重的威胁。根肿菌为专性活体寄生菌,具有强烈的生理小种分化现象,因此,对不同地区的生理小种类型进行评估,有... 详细信息

根肿病是由芸薹根肿菌(Plasmodiophora brassicae Woronin)引起的全球性土传病害,对十字花科芸薹属作物的产量和质量构成了严重的威胁。根肿菌为专性活体寄生菌,具有强烈的生理小种分化现象,因此,对不同地区的生理小种类型进行评估,有利于芸薹属作物的抗性育种及作物栽培的整体规划。精确评估土壤中芸薹根肿菌休眠孢子的数量,有助于准确预测田块中根肿病发生的风险水平,可为后续防治方法的选择和防治效果的评估奠定基础。本文对芸薹根肿菌生理小种的鉴定以及土壤中根肿菌休眠孢子的检测和定量方法进行了简要综述,同时提出了一种有望应用于根肿菌生理小种研究的单细胞测序技术,并对重组酶聚合酶扩增技术(recombinase polymerase amplification,RPA)在根肿菌检测与定量方面的可行性进行了分析。本文旨在为根肿病的高效防控提供理论依据和方法参考,同时为根肿菌鉴定与检测方法的研究提供新的研究思路和解决方案。

关键词：根肿病芸薹根肿菌生理小种根肿病鉴别系统定量方法

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人参皂苷对过氧化氢诱导的Caco-2细胞氧化损伤的保护作用

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食品与发酵工业 2024年第7期50卷 46-50页

作者：刘晓凤卢晓琴钟浩 hussain Muhammad 王丽娜杨梦雨张嘉宁关荣发浙江工业大学食品科学与工程学院浙江杭州310014

为研究人参皂苷对H_(2)O_(2)诱导的人结肠癌(Caco-2)细胞氧化应激损伤的保护作用,构建H_(2)O_(2)诱导的Caco-2细胞氧化损伤模型,以不同质量浓度(10、20、50μg/mL)的人参皂苷干预H_(2)O_(2)诱导后的Caco-2细胞,通过形态学观察,CCK-8法... 详细信息

为研究人参皂苷对H_(2)O_(2)诱导的人结肠癌(Caco-2)细胞氧化应激损伤的保护作用,构建H_(2)O_(2)诱导的Caco-2细胞氧化损伤模型,以不同质量浓度(10、20、50μg/mL)的人参皂苷干预H_(2)O_(2)诱导后的Caco-2细胞,通过形态学观察,CCK-8法检测细胞活力,测定胞内超氧化物歧化酶(superoxide dismutase,SOD)和谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)水平,测定氧化损伤标志物丙二醛(malondialdehyde,MDA)活力以及活性氧(reactive oxygen species,ROS)水平,评价人参皂苷的抗氧化应激水平。结果表明,200μmol/L的H_(2)O_(2)诱导Caco-2细胞4 h后,细胞存活率达到58%左右,符合建模要求。添加10~50μg/mL的人参皂苷明显提升受损细胞的存活率、SOD以及胞内GSH-Px活性,降低受损细胞内ROS和MDA水平,对H_(2)O_(2)诱导的Caco-2细胞氧化应激损伤起到良好的保护作用。

关键词：人参皂苷 Caco-2细胞氧化应激损伤抗氧化能力保护作用

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Aptamers targeting SARS-CoV-2 nucleocapsid protein exhibit potential ant1ip1 an-coronavirus activity

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1186-1198页

作者： Minghui Yang Chunhui Li Guoguo Ye Chenguang Shen Huiping Shi Liping Zhong Yuxin Tian Mengyuan Zhao Pengfei Wu Abid hussain Tian Zhang Haiyin Yang Jun Yang Yuhua Weng Xinyue Liu Zhimin Wang Lu Gan Qianyu Zhang Yingxia Liu Ge Yang Yuanyu Huang Yongxiang Zhao School of Life Science Advanced Research Institute of Multidisciplinary ScienceKey Laboratory of Molecular Medicine and BiotherapyBeijing Institute of TechnologyBeijing 100081China National Clinical Research Center for infectious disease Shenzhen Third People’s HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhen 518112China Guangdong Provincial Key Laboratory of Tropical Disease Research School of Public HealthSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Targeting Oncology National Center for International Research of Biotargeting TheranosticsGuangxi Key Laboratory of Biotargeting TheranosticsCollaborative Innovation Center for Targeting Tumor Diagnosis and TherapyGuangxi Medical UniversityNanning 530021China CAMS Key Laboratory of Antiviral Drug Research Beijing Key Laboratory of Antimicrobial AgentsInstitute of Medicinal BiotechnologyChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Emerging and recurrent infectious diseases caused by human coronaviruses(HCoVs)continue to pose a significant threat to global public health *** light of this ongoing threat,the development of a broad-spectrum drug to combat HCoVs is an urgently ***,we report a series of anti-pan-coronavirus ssDNA aptamers screened using Systematic Evolution of Ligands by Exponential Enrichment(SELEX).These aptamers have nanomolar affinity with the nucleocapsid protein(NP)of Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and also show excellent binding efficiency to the N proteins of both SARS,MERS,HCoV-OC43 and-NL63 with affinity KD values of 1.31 to 135.36 *** aptamer-based therapeutics exhibited potent antiviral activity against both the authentic SARS-CoV-2 prototype strain and the Omicron variant(BA.5)with EC50 values at 2.00 nM and 41.08 nM,*** protein docking analysis also evidenced that these aptamers exhibit strong affinities for N proteins of pan-coronavirus and other HCoVs(−229E and-HKU1).In conclusion,we have identified six aptamers with a high pan-coronavirus antiviral activity,which could potentially serve as an effective strategy for preventing infections by unknown coronaviruses and addressing the ongoing global health threat.

关键词： acute threat conclusion

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不同国家黄油和黄油乳脂理化性质的比较评价

中国油脂 2024年第7期49卷 29-39页

作者：邹孝强蒋邦智郑磊胡纪洁潘月超王钦民 IMAD Khan MUDASSAR hussain 江南大学食品学院食品科学与资源挖掘国家重点实验室国家功能食品工程技术研究中心粮食发酵与食品生物制造国家工程研究中心江苏无锡214122 伽力森食品生物科技(江苏)有限公司江苏泰州225700

为帮助食品生产商和消费者选择适用于不同应用途径的黄油,并为生产更受消费者喜爱的黄油替代品提供理论支持,选取了11个国家的黄油并提取黄油乳脂,对黄油及黄油乳脂的理化性质进行了系统的比较评价。结果表明:11个国家黄油中的脂肪、水... 详细信息

为帮助食品生产商和消费者选择适用于不同应用途径的黄油,并为生产更受消费者喜爱的黄油替代品提供理论支持,选取了11个国家的黄油并提取黄油乳脂,对黄油及黄油乳脂的理化性质进行了系统的比较评价。结果表明:11个国家黄油中的脂肪、水分、蛋白质含量和滑动熔点分别为82.97%~86.40%、12.84%~16.14%、0.45%~0.78%、31.5~33.9℃,酸值(KOH)和过氧化值分别不超过0.32 mg/g、0.029 g/100 g。中国黄油的L值最高(86.87),而新西兰黄油的b值最高(35.28)。所有黄油共检出29种脂肪酸和42种甘油三酯,蛋白质主要由αs1-酪蛋白、β-酪蛋白、κ-酪蛋白、α-乳白蛋白和Adipophilin组成。爱尔兰黄油的不饱和脂肪酸含量最高(35.65%),固体脂肪含量(SFC)较低,而美国、荷兰和澳大利亚黄油的饱和脂肪酸和SFC含量较高。不同国家的黄油和黄油乳脂的晶体均为均匀精细的球晶,其中美国黄油和黄油乳脂的晶体均呈现部分聚集,且绝大多数晶体主要由β′型晶体组成。质地和流变学分析表明,爱尔兰黄油和黄油乳脂的硬度最低,所有黄油和黄油乳脂都表现出良好的黏弹性和剪切变稀性能。综上,不同国家黄油在基本理化性质、脂肪酸和甘油酯组成、SFC及硬度等方面存在差异,在食品工业中需要根据成品、加工工艺等有针对性地选择黄油,在新型人造奶油的构建中,也可依据各黄油特点进行定向研究。

关键词：黄油黄油乳脂理化性质晶体质构流变

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A Framework for Driver DrowsinessMonitoring Using a Convolutional Neural Network and the Internet of Things

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Intelligent Automation & Soft Computing 2024年第2期39卷 157-174页

作者： Muhamad Irsan Rosilah Hassan Anwar Hassan Ibrahim Mohamad Khatim Hasan Meng Chun Lam Wan Mohd Hirwani Wan hussain School of Computing Telkom UniversityBandung40257Indonesia Faculty of Information Science and Technology Universiti Kebangsaan MalaysiaBangi43600Malaysia Department of Electrical Engineering College of EngineeringQassim UniversityAl-Gassim51411Saudi Arabia Graduated School of Business Universiti Kebangsaan MalaysiaBangi43600Malaysia

One of the major causes of road accidents is sleepy *** accidents typically result in fatalities and financial losses and disadvantage other road *** studies have been conducted to identify the driver’s sleepiness and integrate it into a warning *** studies have examined how the mouth and eyelids ***,this limits the system’s ability to identify drowsiness ***,this study designed an Accident Detection Framework(RPK)that could be used to reduce road accidents due to sleepiness and detect the location of *** drowsiness detectionmodel used three facial parameters:Yawning,closed eyes(blinking),and an upright head *** model used a Convolutional Neural Network(CNN)consisting of two *** initial phase involves video processing and facial landmark coordinate *** second phase involves developing the extraction of frame-based features using normalization *** these phases used OpenCV and *** dataset contained 5017 images with 874 open eyes images,850 closed eyes images,723 open-mouth images,725 closed-mouth images,761 sleepy-head images,and 1084 non-sleepy head *** dataset of 5017 images was divided into the training set with 4505 images and the testing set with 512 images,with a ratio of 90:*** results showed that the RPK design could detect sleepiness by using deep learning techniques with high accuracy on all three parameters;namely 98%for eye blinking,96%for mouth yawning,and 97%for head ***,the test results have provided an overview of how the developed RPK prototype can accurately identify drowsy *** findings will have a significant impact on the improvement of road users’safety and mobility.

关键词： Drowsy drivers convolutional neural network openCV microprocessor face detection

甲维盐与阿维菌素对褐飞虱繁殖力及天敌稻虱缨小蜂控害能力的影响

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昆虫学报 2024年第4期67卷 538-548页

作者：何佳春王康逸 Mubashar hussain 魏琪万品俊赖凤香王渭霞傅强中国水稻研究所水稻生物育种全国重点实验室杭州311401 重庆市涪陵区经济作物发展中心重庆408000

【目的】评估甲维盐和阿维菌素两种药剂对褐飞虱Nilaparvata lugens繁殖力及其寄生性天敌稻虱缨小蜂Anagrus nilaparvatae的影响,探明两种药剂引起褐飞虱田间再猖獗的原因。【方法】田间调查了使用5%甲氨基阿维菌素苯甲酸盐(甲维盐)微乳... 详细信息

【目的】评估甲维盐和阿维菌素两种药剂对褐飞虱Nilaparvata lugens繁殖力及其寄生性天敌稻虱缨小蜂Anagrus nilaparvatae的影响,探明两种药剂引起褐飞虱田间再猖獗的原因。【方法】田间调查了使用5%甲氨基阿维菌素苯甲酸盐(甲维盐)微乳剂(microemulsion,ME)(用量225 mL/hm^(2))和5%阿维菌素悬浮剂(suspension concentrate,SC)(用量240 mL/hm^(2))后对田间褐飞虱虫口密度和稻虱缨小蜂成蜂寄生率的影响;室内试验采用稻茎浸渍法测定甲维盐和阿维菌素对褐飞虱4龄若虫的毒力以及不同浓度(LC_(15),LC_(30),LC_(50)和LC_(75))甲维盐和阿维菌素对褐飞虱繁殖力及稻虱缨小蜂成蜂存活和寄生能力的影响,同时采用玻璃管药膜法测定了这两种药剂对稻虱缨小蜂成蜂的毒力,评价了其风险级别。【结果】田间调查结果显示,施用5%甲维盐ME或5%阿维菌素SC显著增加了田间褐飞虱虫口密度,显著降低了稻虱缨小蜂成蜂田间寄生率。室内生物测定结果显示甲维盐和阿维菌素对褐飞虱4龄若虫的LC 50值分别为1.20和2.03 mg/L,各浓度(LC_(15)~LC_(75))甲维盐和中低致死浓度(LC_(15)~LC_(50))阿维菌素处理后的褐飞虱成虫单雌产卵量均显著高于对照。甲维盐和阿维菌素对稻虱缨小蜂成蜂的LC_(50)值分别为0.0145和0.0205 mg/L,田间用量的安全系数分别为4.52×10^(-4)~9.05×10^(-4)和8.52×10^(-4)~14.22×10^(-4),均为极高风险性药剂。【结论】甲维盐和阿维菌素会引起田间褐飞虱的再猖獗,主要有两方面的原因,一是刺激褐飞虱雌成虫产卵,二是作为稻虱缨小蜂的高风险药剂,极大地削弱了该蜂对褐飞虱的控害作用。因此,应减少两种药剂在稻田的使用,避免导致褐飞虱的再猖獗。

关键词：褐飞虱稻虱缨小蜂甲维盐阿维菌素再猖獗繁殖力寄生率

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基于无人机遥感的作物长势监测研究进展

江苏农业科学 2024年第8期52卷 8-15页

作者：赵胜利 Mujahid hussain 王国宾卞志豪王猛兰玉彬山东理工大学农业工程与食品科学学院山东淄博255049 山东理工大学生态无人农场研究院山东淄博255049 山东省农业航空智能装备工程技术研究中心山东淄博255049

无人机遥感技术作为一种新型的农业技术,为精准农业领域的发展提供了重要的技术支持。与传统监测方法相比,无人机遥感具有成本低、时效性强、无大气干扰、分辨率高等优点,为农业信息采集提供了新的工具。无人机农业遥感技术能够高效、... 详细信息

无人机遥感技术作为一种新型的农业技术,为精准农业领域的发展提供了重要的技术支持。与传统监测方法相比,无人机遥感具有成本低、时效性强、无大气干扰、分辨率高等优点,为农业信息采集提供了新的工具。无人机农业遥感技术能够高效、无损地精确采集农业遥感数据,对作物长势进行实时监测,为农业生产提供重要的获取空间数据途径。近年来,随着无人机技术和遥感技术的不断发展和成熟,无人机农业遥感技术的应用范围逐步扩大,涵盖了作物生长监测、精准施肥、精准灌溉、病虫害预警等多个领域。本文重点介绍无人机遥感技术在作物生长监测中的应用,主要介绍了无人机遥感系统的组成、无人机遥感平台和传感器的类型和特点、基于无人机遥感图像数据处理的关键步骤以及作物长势监测的重要指标,综合评估了无人机遥感技术在作物长势监测方面应用的研究现状和存在的问题旨在为后续的无人机遥感技术在作物长势监测中的研究提供参考。

关键词：无人机遥感农业长势应用进展

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