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Computer Modeling in Engineering & Sciences 2021年第8期128卷 639-668页

作者： hung-chun yang Tz-Cheng Chiu Department of Mechanical Engineering National Cheng Kung UniversityTainan701Taiwan

An implicit integration scheme was developed for simulating the viscoplastic constitutive behavior ofSn3.0Ag0.5Cu solder and programmed into a user material subroutine of the finite element software ANSYS. Thenumerical procedure first solves the essential state variables by using a three-level iterative procedure, and updatesthe remaining stress and state variables accordingly. The numerical implementation was applied to consider theresponses of solder joints in an electronic assembly under temperature cycling condition. The viscoplastic strainenergy density accumulation over one temperature cycle was identified as a feasible parameter for evaluating thethermomechanical reliability of the solder joints.

关键词： Pb-free hysteresis ratcheting fatigue tangent modulus

The role of innate immunity in diabetic nephropathy and their therapeutic consequences

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Journal of Pharmaceutical Analysis 2024年第1期14卷 39-51页

作者： Min yang chun Zhang Department of Nephrology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Diabetic nephropathy (DN) is an enduring condition that leads to inflammation and affects a substantial number of individuals with diabetes worldwide. A gradual reduction in glomerular filtration and emergence of proteins in the urine are typical aspects of DN, ultimately resulting in renal failure. Mounting evidence suggests that immunological and inflammatory factors are crucial for the development of DN. Therefore, the activation of innate immunity by resident renal and immune cells is critical for initiating and perpetuating inflammation. Toll-like receptors (TLRs) are an important group of receptors that identify patterns and activate immune responses and inflammation. Meanwhile, inflammatory responses in the liver, pancreatic islets, and kidneys involve inflammasomes and chemokines that generate pro-inflammatory cytokines. Moreover, the activation of the complement cascade can be triggered by glycated proteins. This review highlights recent findings elucidating how the innate immune system contributes to tissue fibrosis and organ dysfunction, ultimately leading to renal failure. This review also discusses innovative approaches that can be utilized to modulate the innate immune responses in DN for therapeutic purposes.

关键词： Innate immunity Diabetic nephropathy Inflammation Toll-like receptor Inflammasomes

The Construction of an Ontology-Based Knowledge Management Model for Departure Procedures

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Advances in Aerospace Science and Technology 2016年第1期1卷 32-47页

作者： Kuo-Wei Su chun-hung yang Po-Hsin Huang Department of Information Management National Kaohsiung First University of Science and Technology Taiwan Department of Industrial Engineering and Engineering Management National Tsing Hua University Taiwan

With increased global economic development, the air traffic volume (including passengers and parcels) increases every year. Thus, the business-related load on air traffic controllers becomes heavier, which influences their need for frequent learning and training opportunities. Therefore, the only solution is to enhance the performance of the training for the air traffic controllers (ATCs) and to build uniform training procedures and standardized training content, which constitute a shared framework with ontology knowledge. Taking departure operation control processes as an example, the research analyzes an aviation organization framework, with information communication procedures and relevant knowledge assets from the viewpoint of departure processes, to explore a knowledge management model of aviation control. This research studies how explicit knowledge is transformed by CommonKADS methodology using the CommonKADS sheet, and the Unified Modeling Language (UML) graph presentation and ontology model are discussed in this research. This analysis procedure can be applied to the systematic analysis and establishment of similar business-based information systems, allowing this research result to be further shared in different industries

关键词： Air Traffic Controllers (ATCs) Departure Procedure Ontology Knowledge CommonKADS Methodology

Solid-conversion synthesis of three-dimensionally ordered mesoporous ZSM-5 catalysts for the methanol-to-propylene reaction

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Frontiers of Chemical Science and Engineering 2024年第8期18卷 111-122页

作者： Weilong chun Chenbiao yang Xu Wang Xin yang Huiyong Chen School of Chemical Engineering Northwest UniversityXi’an 710069China International Science&Technology Cooperation Base for Clean Utilization of Hydrocarbon Resources Chemical Engineering Research Center of the Ministry of Education for Advanced Use Technology of Shanbei EnergyCollaborative Innovation Center for Development of Energy and Chemical Industry in Northern ShaanxiNorthwest UniversityXi’an 710069China

A facile synthesis of hierarchical ZSM-5 with the three-dimensionally ordered mesoporosity(3DOm ZSM-5)was achieved by solid conversion(SC)of SiO_(2)colloidal crystals to high-crystalline *** products of 3DZ5_S/C and 3DZ5_S,which were severally transformed from the carbon-padded SiO_(2)colloidal crystals and the initial SiO_(2)colloidal crystals,exhibited not only a similar ordered structure and acidity but also higher crystallinity and more balanced meso-/micropore combination in comparison with 3DZ5_C obtained by the conventional confined space crystallization *** three synthesized 3DZ5 catalysts showed improved methanol-to-propylene performance than the commercially microporous ZSM-5(CZ5),embodied in five times longer lifetime,higher propylene selectivity and S_(propylene)/S_(ethylene) ratio(P/E),and superior coke toleration with lower formation rate of coke(R_(coke)).Moreover,the 3DZ5_S catalyst in situ converted from SiO_(2)colloidal crystals presented the highest selectivities of propylene(42.51%)and light olefins(74.6%)among all three 3DZ5 *** high efficiency in synthesis and in situ utilization of SiO_(2)colloidal crystals demonstrate the proposed SC strategy to be more efficiently and eco-friendly for the high-yield production of not only 3DOm ZSM-5 but also other types of hierarchical zeolites.

关键词： hierarchical zeolite three-dimensionally ordered mesoporosity ZSM-5 solid conversion methanol-to-propylene

Stercoral perforation of the cecum:A case report

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1189-1194页

作者： hung-chun Yu Ta-Wei Pu Jung-Cheng Kang Chao-yang Chen Je-Ming Hu Ruei-Yu Su Department of Surgery Taichung Armed Forces General HospitalTaichung 411228Taiwan Department of Surgery Tri-Service General HospitalNational Defense Medical CenterTaipei 11490Taiwan Division of Colon and Rectal Surgery Department of SurgeryTri-Service General Hospital Songshan BranchNational Defense Medical CenterTaipei 105Taiwan Division of Colon and Rectal Surgery Department of SurgeryTaiwan Adventist HospitalTaipei 105Taiwan Division of Colon and Rectal Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Department of Pathology Tri-Service General HospitalNational Defense Medical CenterTaipei 105Taiwan Department of Pathology and Laboratory Medicine Taoyuan Armed Forces General HospitalTaoyuan 325Taiwan

BACKGROUND With less than 90 reported cases to date,stercoral perforation of the colon is a rare *** ulceration is thought to occur due to ischemic pressure necrosis of the bowel wall,which is caused by the presence of a stercoraceous *** underscore this urgent surgical situation concerning clinical presentation,surgical treatment,and results,we present the case of a 66-year-old man with a stercoral *** SUMMARY A 66-year-old man with a history of hypertension,hyperlipidemia,and gout presented at the emergency department with lower abdominal pain and a low-grade fever lasting for a few *** computed tomography indicated a suspected bezoar(approximately 7.6 cm)in the dilated cecum,accompanied by pericolic fat stranding,mild proximal dilatation of the ileum,pneumoperitoneum,and minimal ***,feculent peritonitis with isolated cecal perforation were ***,a right hemicolectomy with peritoneal lavage was performed.A histopathological examination supported the intraoperative *** In stercoral perforations,a diagnosis should be diligently pursued,especially in older adults,and prompt surgical intervention should be implemented.

关键词： Acute abdomen Colectomy Peritoneal lavage Pneumoperitoneum Bezoars Case report

Deposition of shear-thinning viscoelastic fluids by an elongated bubble in a circular channel regarding the weakly elastic regime

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Droplet 2024年第3期3卷 49-56页

作者： SungGyu chun Zhengyu yang Jie Feng Department of Mechanical Science and Engineering University of Illinois Urbana-ChampaignUrbanaIllinoisUSA Materials Research Laboratory University of Illinois Urbana-ChampaignUrbanaIllinoisUSA

Thin-film deposition of fluids is ubiquitous in a wide range of engineering and biological applications,such as surface coating,polymer processing,and biomedical device *** the thin viscous film deposition in Newtonian fluids has been extensively investigated,the deposition dynamics in frequently encountered non-Newtonian com-plex fluids remain elusive,with respect to predictive scaling laws for the film ***,we investigate the deposition of thin films of shear-thinning viscoelastic fluids by the motion of a long bubble translating in a circular capillary *** the weakly elastic regime with a shear-thinning viscosity,we provide a quantitative measurement of the film thickness with systematic *** further harness the recently developed hydrodynamic lubrication theory to quantitatively rationalize our experimental observations considering the effective capillary number Cae and the effective Weissenberg number Wie,which describe the shear-thinning and the vis-coelastic effects on the film formation,*** obtained scaling law agrees reasonably well with the experimentally measured film thickness for all test *** work may potentially advance the fundamental understanding of the thin-film deposi-tion in a confined geometry and provide valuable engineering guidance for processes that incorporate thin-film flows and non-Newtonian fluids.

关键词： film weakly bubble

Roles of fibroblast growth factors in the treatment of diabetes

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World Journal of Diabetes 2024年第3期15卷 392-402页

作者： chun-Ye Zhang Ming yang Bond Life Sciences Center University of MissouriColumbiaMO 65211United States Department of Surgery University of MissouriColumbiaMO 65212United States NextGen Precision Health Institution University of MissouriColumbiaMO 65212United States

Diabetes affects about 422 million people worldwide,causing 1.5 million deaths each ***,the incidence of diabetes is increasing,including several types of *** 1 diabetes(5%-10%of diabetic cases)and type 2 diabetes(90%-95%of diabetic cases)are the main types of diabetes in the *** evidence shows that the fibroblast growth factor(FGF)family plays important roles in many metabolic disorders,including type 1 and type 2 *** consists of 23 family members(FGF-1-23)in ***,we review current findings of FGFs in the treatment of diabetes and management of diabetic *** FGFs(e.g.,FGF-15,FGF-19,and FGF-21)have been broadly investigated in preclinical studies for the diagnosis and treatment of diabetes,and their therapeutic roles in diabetes are currently under investigation in clinical ***,the roles of FGFs in diabetes and diabetic complications are involved in numerous ***,FGF intervention can prevent high-fat diet-induced obesity and insulin resistance and reduce the levels of fasting blood glucose and triglycerides by regulating lipolysis in adipose tissues and hepatic glucose ***,modulation of FGF expression can inhibit renal and cardiac fibrosis by regulating the expression of extracellular matrix components,promote diabetic wound healing process and bone repair,and inhibit cancer cell proliferation and ***,FGFs can regulate the activation of glucoseexcited neurons and the expression of thermogenic genes.

关键词： Fibroblast growth factors Type 1 diabetes Type 2 diabetes Metabolic disorders Treatment Clinical trials

Community perspectives on the effectiveness of watershed management institutions in the Himalayas

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Journal of Mountain Science 2024年第4期21卷 1119-1139页

作者： Nisha SILWAL Nabin DhungANA Rajan SUBEDI Suraj UPADHAYA chun-hung LEE Natural Resources Conservation Nepal(NRCN) ChitwanP.O.Box 44200Nepal Department of Natural Resources and Environmental Studies College of Environmental StudiesNational Dong Hwa UniversityHualien 97401Chinese Taipei Institute of Forestry Tribhuvan UniversityPokharaP.O.Box 43Nepal School of Agriculture and Natural Resources Kentucky State UniversityFrankfortKY 40601USA Himalayan Conservation and Research Institute DolpaP.O.Box 21400Nepal

The sustainability of environmental management initiatives,such as watershed management programs,relies on the presence of effective institutions at the watershed ***,there needs to be more empirical evidence from evaluating the effectiveness of watershed-level ***,this study presents a pioneering effort to evaluate the effectiveness of Nepal’s first watershed conservation committee at the watershed scale,focusing on the case of the Khageri Khola watershed in Central *** study involved conducting a household survey,key informant interviews,focus group discussions,and field observations to collect and analyze the *** analysis,index value calculation,and chi-square statistics were then employed to summarize the results regarding local respondents’perceptions of twelve institutional characteristics,their rationalities,and their association with socio-demographic *** results reveal that the watershed conservation committee was perceived as performing well in managing the ***,good interaction,appropriate scale,technical,environmental,social,organizational,and government rationality were perceived as highly effective,with an average index value of less than *** contrast,clarity of objectives and economic rationality showed moderate effectiveness,with an average index value ranging from 0.36 to ***,the results suggested that adaptiveness,compliance capacity,and financial rationality merit increased attention,intending to improve their ***,the results showed the association of socio-demographics with respondents’perceptions of various indicators of institutional characteristics and their ***,the study provides valuable insights for policymakers,researchers,and development practitioners charged with designing sustainable and effective programs and *** enhance the effectiveness and sustainability of watershed management programs,we recommen

关键词： Watershed Watershed institutions Indicators Institutional characteristics Rationalities Nepal.

Mechanically driven assembly of biomimetic 2D-material microtextures with bioinspired multifunctionality

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Nano Research 2024年第2期17卷 663-678页

作者： yang Li Lin Jing Joshua M.Little Haochen yang Tsai-chun Chung Po-Yen Chen Department of Chemical and Biomolecular Engineering University of MarylandCollege ParkMD 20740USA Maryland Robotics Center University of MarylandCollege ParkMD 20742USA School of Materials Science and Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798Singapore

Nature provides a wealth of bio-inspiration for advanced material *** various nanomaterials into biomimetic microtextures with bioinspired functionalities has spurred increasing research interests and facilitated technological advances in various *** recent years,two-dimensional materials(2DMs)have emerged as important building block units in the biomimicry field due to their distinct chemical,physical,electrical,electrochemical,and catalytic *** this review article,various mechanically driven assembly approaches are summarized to fabricate various genealogies of biomimetic 2DM microtextures with bio-inspired ***,sequential deformation strategies are discussed to programmably construct higher dimensional 2DM microtextures,ranging from wrinkles/crumples(one-time deformation)to multiscale hierarchies(multiple deformations).Next,the current progress using higher dimensional 2DM microtextures to imitate different biological structures and/or induce bio-inspired multifunctionality is systematically *** showcases of bio-inspiration and biomimicry using different 2DM nanosheets are highlighted:(1)wrinkle patterns of an earthworm that spur the design of strain sensors with programmable working ranges and sensitivities,(2)wrinkle appearance of a Shar-Pei dog that motivates the fabrication of stretchable energy storage devices,(3)hierarchical scale textures of a desert lizard that inspire cation-induced gelation platforms for 2DM aerogels,and(4)wrinkle skin of an elephant that influences the development of 2DM protective skin for soft ***,challenges and future opportunities of adopting 2DM nanosheets to assemble biomimetic microstructures with synergistic functionalities are discussed.

关键词： two-dimensional(2D)materials mechanically driven assembly biomimetic microtextures functional nanocomposite bio-inspired multifunctionality

Conversion hip arthroplasty for failed nailing of intertrochanteric fracture: Reflections on some important aspects

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World Journal of Orthopedics 2024年第10期15卷 997-1000页

作者： Fu-chun yang Department of Orthopedic Trauma and Hand Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

In this editorial,I present my comments on the article by Solarino et *** hip arthroplasty,which is an optional salvage procedure performed following unsuccessful fixation of intertrochanteric femur fractures in elderly pati-ents,entails more complex processes and higher rates of operative complications than primary ***,it is important to consider the appropriateness of the primary treatment choice,as well as the adequacy of nailing fixation for intertrochanteric *** article briefly analyzes the possible factors contributing to the nailing failure of intertrochanteric fractures and attempts to find corresponding countermeasures to prevent fixation *** also analyzes the choice of treatment between nailing fixation and primary arthroplasty for intertrochanteric fractures.

关键词： Intertrochanteric femur fracture Femoral nailing fixation Primary hip arthroplasty Conversion hip arthroplasty Failed internal fixation Treatment reflection