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Journal of Quantum Information Science 2024年第2期14卷 29-51页

作者： Sudha Alevoor Raghavendra Usha Devi Akshata Shenoy Hejamadi Hosapete Seshadri Karthik humera talath Bada Palaiah Govindaraja Attipat Krishnaswamy Rajagopal Department of Physics Kuvempu University Shimoga India Inspire Institute Inc. Alexandria Virginia USA Department of Physics Bangalore University Bangalore India International Centre for Theory of Quantum Technologies University of Gdnsk Gdnsk Poland

We explore the entanglement features of pure symmetric N-qubit states characterized by N-distinct spinors with a particular focus on the Greenberger-Horne-Zeilinger (GHZ) states and , an equal superposition of W and obverse W states. Along with a comparison of pairwise entanglement and monogamy properties, we explore the geometric information contained in them by constructing their canonical steering ellipsoids. We obtain the volume monogamy relations satisfied by states as a function of number of qubits and compare with the maximal monogamy property of GHZ states.

关键词： Permutation Symmetric States Monogamy Pairwise Entanglement

Contemporary Study for Detection of COVID-19 Using Machine Learning with Explainable AI

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Computers, Materials & Continua 2024年第7期80卷 1075-1104页

作者： Saad Akbar humera Azam Sulaiman Sulmi Almutairi Omar Alqahtani Habib Shah Aliya Aleryani Department of Computer Science University of KarachiKarachi75270Pakistan Department of Computing Faculty of Engineering Science and TechnologyHamdard UniversityKarachi75540Pakistan Department of Health Informatics College of Applied Medical SciencesQassim UniversityQassim51452Saudi Arabia Department of Computer Science College of Computer ScienceKing Khalid UniversityAbha61421Saudi Arabia

The prompt spread of COVID-19 has emphasized the necessity for effective and precise diagnostic *** this article,a hybrid approach in terms of datasets as well as the methodology by utilizing a previously unexplored dataset obtained from a private hospital for detecting COVID-19,pneumonia,and normal conditions in chest X-ray images(CXIs)is proposed coupled with Explainable Artificial Intelligence(XAI).Our study leverages less preprocessing with pre-trained cutting-edge models like InceptionV3,VGG16,and VGG19 that excel in the task of feature *** methodology is further enhanced by the inclusion of the t-SNE(t-Distributed Stochastic Neighbor Embedding)technique for visualizing the extracted image features and Contrast Limited Adaptive Histogram Equalization(CLAHE)to improve images before extraction of ***,an AttentionMechanism is utilized,which helps clarify how the modelmakes decisions,which builds trust in artificial intelligence(AI)*** evaluate the effectiveness of the proposed approach,both benchmark datasets and a private dataset obtained with permissions from Jinnah PostgraduateMedical Center(JPMC)in Karachi,Pakistan,are *** 12 experiments,VGG19 showcased remarkable performance in the hybrid dataset approach,achieving 100%accuracy in COVID-19 *** classification and 97%in distinguishing normal ***,across all classes,the approach achieved 98%accuracy,demonstrating its efficiency in detecting COVID-19 and differentiating it fromother chest disorders(Pneumonia and healthy)while also providing insights into the decision-making process of the models.

关键词： COVID-19 detection deep neural networks support vector machine CXIs InceptionV3 VGG16 VGG19 t-SNE embedding CLAHE attention mechanism XAI

Identified Analytical Profile for Microelements, Trace Metals, Amino Acids and Screening of Anti-Diabetic Activity from Flower and Leaf Extracts of Moringa oleifera in Streptozotocin (STZ)-Induced Diabetic Rats

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Pharmacology & Pharmacy 2022年第6期13卷 149-163页

作者： Hemalatha Kamurthy Sirajunisa talath Department of Pharmacognosy Acharya & BM Reddy College of Pharmacy Bangalore India Department of Pharmaceutical Chemistry RAK College of Pharmacy RAKMHSU Ras Al Khaimah UAE

Background: Moringa oleifera plant is popularly known for its rich phytoconstituents and nutritional value and important medicinal values in both traditional and modern systems of medicine. We explored the present study for measurements of microelements, amino acid, phenolic content in hydro-al-coholic flower and leaf extracts of Moringa oleifera along with anti-diabetic activity in Streptozotocin (STZ)-induced diabetic male Wistar rats. Methodology: The micronutrients were determined by using atomic absorption spectrophotometer at 285 nm and 422 nm for Calcium (Ca), phosphorus (P), Iron (Fe), and Zinc (Zn), etc. The trace elements were also measured by spectrophotometer. The essential amino acid was determined by using Amino acid analyser. The total phenolic content in hydro-alcoholic extracts (flower and leaf) M. oleifera measured the absorbance at 760 nm by UV spectrophotometer. The screening of anti-diabetic activity HAFE and HALE of Moringa oleifera at two different dose of 100 and 200 mg/kg b.w. for 21 days were performed by determining the changes in biochemical parameters. Result and Discussion: The results revels that the presence of micronutrients, trace elements and amino acids in both flower and leaf of M. oleifera. The hydrolaocholic extracts of HAFE and HALE at 200 mg/kg b.w. showed significant antidiabetic activity compared with standard Glibenclamide. Whereas dose at 100 mg/kg b.w. showed moderate activity. Conclusion: In conclusion, the M. oleifera exhibits more effectiveness against STZ-induced diabetes. The HAFE and HALF extracts exhibited significant anti-diabetic property and active components may be isolated and clinical studies is required for further evaluation. Because of the rich source of phytoconstients, nutritional elements will be helpful in processed food products as dietary supplements especially for malnutrition in children in the current era.

关键词： Moringa oleifera Microelements Nutritional Values Gallic Acid Amino Acids Streptozotocin Glibenclamide

Degradation study of different brands of paracetamol by UV spectroscopy

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Journal of Coastal Life Medicine 2016年第5期4卷 377-379页

作者： Safila Naveed humera Ishaq Sheeba Urooj Faculty of Pharmacy Jinnah University for WomenKarachiPakistan Faculty of Pharmacy Hamdard UniversityKarachiPakistan

Objective:To investgate the forced degradation study for the determination of degradation of the drug ***:Paracetamol was exposed to different conditions according to International Conference on Harmonization *** amount of degradation product can be calculated with the help of UV *** official test limits according to British Pharmacopoeia/United States Pharmacopoeia should not less than and should not more than lapelled *** degradation of drug substance was exposed to acidic and basic medium of *** degradation of drug substance of panadol,disprol and calpol were also observed negligible difference in availability on exposure to UV and *** method can be used successfully for studying the stress degradation *** this method is less time consuming and simple and cost effective ***:The brands ***,panadol and disprol,when they come in contact with different degradation parameters(before,acid,base,heat and UV treatments)according to statistical analysis,the result showed significant values(P<0.05)which indicated that there was no degradation in any of the ***:The result indicated there is no degradation found in these brands.

关键词： Paracetamol Degradation studies Different brands Spectrophotometer

High Frequency Plant Regeneration from Leaf Derived Callus of <i>Dianthus caryophyllus</i>L.

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American Journal of Plant Sciences 2014年第15期5卷 2454-2463页

作者： Muhammad Arif Saima Rauf Aziz Ud Din Mamoona Rauf humera Afrasiab Department of Botany University of the Punjab Quaid-e-Azam Campus Lahore Pakistan Department of Genetics Hazara University Garden Campus Mansehra Pakistan Institute of Agricultural Sciences University of the Punjab Lahore Pakistan National Institute for Biotechnology and Genetic Engineering Faisalabad Pakistan

An efficient procedure was developed for in vitro callus induction, proliferation and regeneration of carnation cultivar (Dianthus caryophyllus L.) using leaf, nodal and inter-nodal explants on Murashige and Skoog’s medium (MS) supplemented with exogenous plant growth regulators. For morphogenic callus induction and proliferation from various explants, MS medium supplemented with 3.0 mg/l 2,4-D was highly efficient with 100% callus induction frequency from inter-nodal explants. Leaf explants showed quicker response than nodal and inter-modal explants, for callus initiation within 6 days of inoculation. Best grown callus was obtained from leaf explant. The leaf-derived callus was maintained up to several weeks, which indicated that 8-week incubation period was the most suitable for obtaining well proliferated, morphogenic callus. Temperature variation also affected the growth of in vitro induced morphogenic callus from various explants. Results have shown that 27°C proved to be the best temperature for morphogenic callus induction and proliferation from leaf and inter-nodal explants. Among the auxin-cytokinin combination, MS medium containing 1.0 mg/l N(6)-benzylaminopurin (BAP) and 2.0 mg/l NAA showed the highest efficiency of callus initiation and proliferation from leaf, nodal and inter-nodal explants. Light conditions proved better for callogenesis and proliferation from leaf, nodal and inter-nodal explants. Regeneration response from well grown morphogenic callus was prominent on MS medium supplemented with 3.0 mg/l BAP alone and 1.0 mg/l NAA with 3.0 mg/l BAP.

关键词： Dianthus caryophyllus L. Regeneration Potential Plant Growth Regulators Morphogenic Callus Induction

Hypothyroidism—A Question towards Quality and Patient Centricity

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Open Journal of Endocrine and Metabolic Diseases 2015年第2期5卷 19-27页

作者： Hina Rehman Syed Junaid Rehan humera Ishaq Sadia Shakeel Faraz Hashmi Safila Naveed Faculty of Pharmacy Jinnah University for Women Karachi Pakistan Faculty of Pharmacy Hamdard University Karachi Pakistan Jinnah Sindh Medical University Karachi Pakistan

The metabolic and endocrine disorders are either increasing across the globe or may have been observed with more focus in recent years. It is not uncommon now to find out neither patients of endocrine and metabolic disorders nor a physician of the associated diseases. There were 42 million people who had thyroid disorders including hypothyroidism according to the survey of endocrine society of India. Hypothyroidism is said when less activity of thyroid glands is observed then the normal. So, to evaluate the quality standard, empowerment and patient centricity in Pakistan with present prevalence of hypothyroidism in different age groups, gender along with the prescribed medication against pre diagnosed disease and associated co-morbidities, the study is designed with a questionnaire development including both qualitative and quantitative variables. Study was conducted on various OPD’s, profit and not for profit secondary and tertiary care hospitals and consultant clinics during July 2013 to Jan 2014 and it was given consideration to include people from all areas of life with minimization of any unforeseen biasness and comprehensive data. After full filling the inclusion criteria, 102 patients were selected as study participants. After completion and reviewing the questionnaire, data were analyzed by 21.00 SPSS version. Chi square/ fisher test, spearmen’s rank correlation were applied for categorical quantitative variable. Paired t test before and after were applied for qualitative variable. Highly significant reliability of items in the questionnaire was found along with inter item correlation (P < 0.05). Out of 102 patients of the study, 80 patients fell into the inclusion criteria, while 22 were excluded. A total of 80 patients were registered in the incorporate duration. Among the total samples 36 (42.9%) were males and 44 (52.4%) were females. Mean age males and females included in the study were 34.89 ± 17.73 and 33.36 ± 13.73 years respectively. The systolic an

关键词： Hypothyroidism Quality Patient Centricity Empowerment

A New Attempt to Neutrosophic Soft Bi-Topological Spaces

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Computer Modeling in Engineering & Sciences 2022年第3期130卷 1565-1585页

作者： Arif Mehmood Muhammad Aslam Muhammad Imran Khan humera Qureshi Choonkil Park Jung Rye Lee Department of Mathematics&Statistics Riphah International UniversitySector I-14Islamabad44000Pakistan Department of Mathematics College of SciencesKing Khalid UniversityAbha61413Saudi Arabia Department of Pure and Applied Mathematics(Statistics) University of HaripurHaripur22630Pakistan Research Institute for Natural Sciences Hanyang UniversitySeoul04763Korea Department of Data Science Daejin UniversityKyunggi11159Korea

In this article,new generalized neutrosophic soft∗b open set is introduced in neutrosophic soft bi-topological structurers(NSBTS)concerning soft points of the *** new set is produced by making the marriage of soft semi-open set with soft pre-open set in neutrosophic soft topological *** ample of results are investigated in NSBTS on the basis of this new neutrosophic soft∗b open *** examples are settled for justification of these *** non-validity of some results is vindicated with examples.

关键词： Neutrosophic soft set(NSS) neutrosophic soft points(NSP) neutrosophic soft bi-topological structurers(NSBTS) neutrosophic soft∗b-open set and neutrosophic soft∗b-separation axioms

Alleviation of mycotoxin biodegradation agent on zearalenone and deoxynivalenol toxicosis in immature gilts

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Journal of Animal Science and Biotechnology 2018年第3期9卷 727-737页

作者： Donghui Shi Jianchuan Zhou Lihong Zhao Xiaoping Rong Yu Fan humera Hamid Wenqiang Li Cheng Ji Qiugang Ma State Key Laboratory of Animal Nutrition China Agricultural UniversityBeijing 100193People’s Republic of China Liaoning Medical University Jinzhou 121001People’s Republic of China Fuqing Fengze Agricultural Science and Technology Development Co.Ltd. Fuzhou 350011People’s Republic of China State Key Laboratory of Direct-Fed Microbial Engineering Beijing 100193People’s Republic of China

Background: The current study was carried out to evaluate the effects of mycotoxin biodegradation agent(MBA, composed of Bacillus subtilis ANSB01 G and Devosia sp. ANSB714) on relieving zearalenone(ZEA) and deoxynivalenol(DON) toxicosis in immature ***: A total of forty pre-pubertal female gilts(61.42 ± 1.18 kg) were randomly allocated to four diet treatments: CO(positive control); MO(negative control, ZEA 596.86 μg/kg feed and DON 796 μg/kg feed);COA(CO + 2 g MBA/kg feed); MOA(MO + 2 g MBA/kg feed). Each treatment contained 10 replicates with 1 gilt per replicate. Gilts were housed in an environmentally controlled room with the partially slatted ***: During the entire experimental period of 28 d, average daily gain(ADG) and average daily feed intake(ADFI)of gilts in MO group was significantly reduced compared with those in CO group. The vulva size of gilts was significantly higher in MO group than CO group. In addition, significant increases in the plasma levels of Ig A,Ig G, IL-8, IL-10 and PRL were determined in MO group compared with that in CO group. ZEA and DON in the diet upregulated apoptotic caspase-3 in ovaries and uteri, along with down-regulated the anti-apoptotic protein Bcl-2 in ovaries. The supplementation of MBA into diets co-contaminated with ZEA and DON significantly increased ADG, decreased the vulva sizes, reduced the levels of Ig G, IL-8 and PRL in plasma, and regulated apoptosis in ovaries and uteri of ***: The present results indicated that feeding diet contaminated with ZEA and DON simultaneously(596.86 μg/kg + 796 μg/kg) had detrimental effects on growth performance, plasma immune function and reproductive status of gilts. And MBA could reduce the negative impacts of these two toxins, believed as a promising feed additive for mitigating toxicosis of ZEA and DON at low levels in gilts.

关键词： Apoptosis Deoxynivalenol Mycotoxin biodegradation agent Serum parameter Vulva size Zearalenone

Antidiabetic Potential of Carthamus oxycantha ***. Seeds in Alloxan Induced Diabetic Rats

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Pharmacology & Pharmacy 2022年第6期13卷 189-198页

作者： Ali Imran Abid Hira Muzammel humera Shafi Mouqadus Un Nisa Hassan Ali Muhammad Waqar Afzal Nadeem UL Hassan Khan Fahad Muzammil Department of Pharmacology Faculty of Pharmacy The University of Lahore Lahore Pakistan Department of Pharmacology Faculty of Pharmacy Bahauddin Zakriya University Multan Pakistan

Ethnopharmacological Relevance: Diabetes Mellitus is one of the most common disorders of metabolic abnormalities. It is characterized by hyperglycemia followed by abnormalities in insulin release, insulin work, or both. This persistent hyperglycemia is concerned with long-term complications, dysfunction and collapse of various organs, notoriously the kidneys, heart, nerves, blood vessels and eyes. The seeds of the Carthamus oxycantha have been used by the practitioners as a traditional remedy for diabetes mellitus in the rural areas of district Jhang as well as other areas of Pakistan. Aim of the Study: The purpose of the present study was to reveal the antidiabetic capability of seeds of Carthamus oxycantha in short-term and long-term studies. Materials and Methods: Aqueous ethanolic extract of seeds was prepared by a rotary evaporator. The antidiabetic activity of the seeds was assessed by using normoglycemic and glucose loaded rats. However, two kinds of studies i.e. short-term as well as long-term treatment were carried out in alloxan induced diabetic rats for the finalized both doses i.e. 50 mg/kg and 100 mg/kg. Blood samples were tested by an electrochemical technique using a glucometer. Results: The promising results were achieved for the antidiabetic potential of the ethanolic extract of seeds of Carthamus oxycantha at both of the doses i.e. 50 mg/kg and 100 mg/kg. The antihyperglycemic potential was also evaluated in normoglycemic and glucose loaded animals. Treatment with 100 mg/kg AEECO presented significant reduction (p < 0.05) as well as highly significant reduction (p < 0.01) in short term and long term study. Statistical data showed that AEECO presented comparable effects to that of the standard drug Glibenclamide at 0.5 mg/kg. Phytochemical studies of AEECO also disclosed the presence of flavonoids, resins, glycosides, steroids and alkaloids. In conclusion, the antidiabetic properties of AEECO may be attributed either due to the release of insulin or

关键词： Diabetes Mellitus Carthamus oxycantha Alloxan Glibenclamide AEECO