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不同温度下PEG模拟干旱对濒危植物狭叶坡垒种子萌发的影响

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广西植物 2024年第1期44卷 68-76页

作者：梁惠子杨继生覃毅潘韦虎肖玉菲黄荣林王仁杰蒋燚刘雄盛广西壮族自治区林业科学研究院广西优质用材林资源培育重点实验室南宁530002 广西防城金花茶国家级自然保护区广西防城港538021

狭叶坡垒(Hopea chinensis)种子为典型的顽拗性种子。为探究种子萌发对温度和水分的适应性,该研究在人工气候培养箱内设置3种温度(15、20、25℃),采用6个聚乙二醇(PEG-6000)浓度(0%、5%、10%、15%、25%和35%)模拟干旱胁迫处理,研究狭叶... 详细信息

狭叶坡垒(Hopea chinensis)种子为典型的顽拗性种子。为探究种子萌发对温度和水分的适应性,该研究在人工气候培养箱内设置3种温度(15、20、25℃),采用6个聚乙二醇(PEG-6000)浓度(0%、5%、10%、15%、25%和35%)模拟干旱胁迫处理,研究狭叶坡垒种子的萌发特性。结果表明:(1)温度对种子萌发具有显著影响。同一干旱胁迫浓度下,种子的萌发率、萌发势、萌发指数、胚根长、芽长和活力指数随着温度升高呈上升趋势,萌发时滞随温度升高而降低,萌发历期随温度升高而波动性上升。(2)干旱胁迫对种子萌发具有显著影响。同一温度下,种子的萌发率、萌发势、萌发指数、萌发历期、胚根长、胚芽长和活力指数随着干旱胁迫程度加重呈降低的趋势,萌发时滞随干旱胁迫程度加重而升高。(3)温度和干旱胁迫的交互作用对种子萌发具有显著影响。干旱胁迫下,不同温度条件下种子萌发的表现不同。在35%PEG-6000胁迫下,20℃和25℃时,种子萌发率分别为8.89%和15.55%,显著高于15℃(0%)。综上所述,适宜种子萌发的温度为20℃和25℃,适宜幼苗早期生长最佳温度为25℃;干旱程度越大,种子萌发受到的抑制作用越强,干旱胁迫对种子萌发的影响高于温度因素,适当增温可缓解干旱胁迫对种子萌发的抑制作用。

关键词：濒危植物狭叶坡垒温度干旱胁迫种子萌发

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A novelα-ketoamide reactivity-based two-photon fluorogenic probe for visualizing peroxynitrite in Parkinson's disease models

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创新光学健康科学杂志(英文) 2023年第4期16卷 79-89页

作者： Tao Shao Xianning Xu Lan Wang Yu Shen Jun Zhao huizi Li Duoteng Zhang Wei Du Hua Bai Bo Peng Lin Li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics(IFE)and Xi'an Institute of Biomedical Materials&Engineering Northwestern Polytechnical University Xi'an 710072P.R.China Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM)Nanjing Tech University(NanjingTech) Nanjing 211816P.R.China Department of Outpatient PLA Rocket Force Characteristic Medical Center Beijing 100088 P.R.China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005FujianP.R.China

Peroxynitrite(ONOO^(-))contributes to oxidative stress and neurodegeneration in Parkinson's disease(PD).Developing a peroxynitrite probe would enable in situ visualization of the overwhelming ONOO^(-)flux and understanding of the ONOO^(-)stress-induced neuropathology of ***,a novelα-ketoamide-based fluorogenic probe(DFlu)was designed for ONOO^(-)monitoring in multiple PD *** results demonstrated that DFlu exhibits a fluorescence turn-on response to ONOO^(-)with high specificity and *** efficacy of DFlu for intracellular ONOO^(-)imaging was demonstrated *** results showed that DFlu can successfully visualize endogenous and exogenous ONOO^(-)in cells derived from chemical and biochemical *** importantly,the two-photon excitation ability of DFlu has been well demonstrated by monitoring exogenous/endogenous ONOO^(-)production and scavenging in live zebraflsh PD *** work provides a reliable and promisingα-ketoamide-based optical tool for identifying variations of ONOO^(-)in PD models.

关键词： α-Ketoamide two-photon fluorogenic probe bioimaging peroxynitrite Parkinson's disease.

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河南省慢性肾病流行现状及危险因素分析

现代疾病预防控制 2024年第6期35卷 407-412页

作者：田惠子闫雅丽李卉王梦微高莉冯石献康锴河南省疾病预防控制中心慢性非传染性疾病防治研究所河南郑州450016

目的分析河南省慢性肾病(CKD)流行现状及主要危险因素,为CKD防控提供科学依据。方法2018年,采用多阶段整群随机抽样的方法抽取河南省14个县(区)≥18岁常住居民开展现场调查,通过问卷调查、体格检查、血尿常规及生化检测获取数据,采用多... 详细信息

目的分析河南省慢性肾病(CKD)流行现状及主要危险因素,为CKD防控提供科学依据。方法2018年,采用多阶段整群随机抽样的方法抽取河南省14个县(区)≥18岁常住居民开展现场调查,通过问卷调查、体格检查、血尿常规及生化检测获取数据,采用多因素logistic回归分析CKD相关危险因素。结果共纳入有效调查对象8406人,CKD患病率为9.97%(95%CI:8.73%~11.21%)。多因素logistic回归分析显示,≥60岁人群发生CKD的风险是18~10 h的人群发生CKD的风险是每日睡眠时间6~≤10 h的人群的1.341倍(95%CI:1.111~1.617);存在中心性肥胖、高血压、糖尿病、血脂异常、高尿酸血症的人群发生CKD的风险分别是不患有此类疾病者的1.254倍(95%CI:1.088~1.445)、1.521倍(95%CI:1.321~1.750)、1.907倍(95%CI:1.621~2.244)、1.176倍(95%CI:1.021~1.355)、2.173倍(95%CI:1.788~2.640)。结论河南省≥18岁居民CKD患病率接近全国平均水平,高龄、睡眠时间过长、中心性肥胖、高血压、糖尿病、血脂异常、高尿酸血症是CKD的主要危险因素。

关键词：慢性肾病患病率危险因素中国成人慢性病与营养监测

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儿童医院互联网用药服务体系的构建与应用

儿科药学杂志 2024年第2期30卷 18-22页

作者：孙冲邢慧资李依琪赵云闫聪聪张胜男河南省儿童医院/郑州儿童医院郑州450018

目的:探讨儿童医院如何利用“互联网+药学服务”和药品配送模式,为患儿家长提供全面的儿科药学服务,使患儿家长足不出户即可安全有效地获得高质量药学服务。方法:基于我院互联网医院,建立处方前置审方平台、移动药学服务平台、药品配送... 详细信息

目的:探讨儿童医院如何利用“互联网+药学服务”和药品配送模式,为患儿家长提供全面的儿科药学服务,使患儿家长足不出户即可安全有效地获得高质量药学服务。方法:基于我院互联网医院,建立处方前置审方平台、移动药学服务平台、药品配送系统,统计分析2021年8月1日-2022年8月1日药学服务事件中处方审核、用药交代、科普宣教、线上咨询、药品配送等相关数据。结果:互联网用药服务体系运行后,药师总计前置审方2 284 985张,不合理处方总计172 324张,不合格率为7.54%,其中不合理因素主要是用法用量不适宜和适应证不适宜,占不合理处方的73.91%。建立了三维用药交代体系。共发布227篇原创科普文章,其中文字类162篇,视频类65篇。互联网用药咨询次数达到2 460例次,平均每天6.8例次。患儿年龄主要集中在7岁以内,占总咨询人数的86.40%。用药咨询主要集中在12个科室,呼吸科、皮肤科、消化科咨询例数占69.27%,与儿童常见患病种类相符。互联网用药咨询问题主要集中在用法用量、药品储存,共占比77.64%。目前总计配送药品单数390单,日均配送4.3单。其中河南省内334单,省外56单。结论:我院构建了互联网儿童用药服务体系,大力开展互联网诊疗服务,进一步完善“互联网+医疗健康”服务功能,使药师药学服务贯穿在患儿就诊的全过程,提升和挖掘了药师的价值。

关键词：儿童用药服务互联网+药学服务处方审核药品配送

On Forming a Child-friendly Environment in Urban Communities

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The Journal of Human Rights 2019年第6期18卷 743-762页

作者：池丽萍 NIU huizi(译) School of Children’s Development and Education China Women’s University 不详

The community is both a learning and living environment that significantly influences the physical and mental development of the children,as well as an important arena for realizing children’s ***,the development of urban communities in China is not particularly child-friendly,causing children to abandon or misuse the communal *** a child-friendly environment in urban communities requires the adoption of three basic approaches,i.e.a shift from the"adult’s perspective"to the"child’s perspective",a shift from a simplistic focus on the"hardware"of the environment to a dual focus that balances both"hardware"and"software",as well as a shift from providing an environment to man aging and guiding the use of the *** technical indicators for developing child-friendly environments in urban communities,which based on these three approaches,should be designed.

关键词： child-friendly communities children’s rights environment-friendly service-friendly

基于UPLC指纹图谱与多成分定量评价不同产地桑叶药材质量

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天津中医药大学学报 2024年第3期43卷 207-211页

作者：吕振国赵鹏武恬恬欧阳慧子何俊天津中医药大学组分中药国家重点实验室天津301617 现代中医药海河实验室天津301617

[目的]建立桑叶超高效液相色谱(UPLC)指纹图谱,结合化学计量学与多成分含量测定综合评价不同产地桑叶药材质量。[方法]采用CORTECS UPLC C18色谱柱(2.1 mm×100 mm,1.6μm),以0.1%甲酸水-乙腈为流动相在350 nm波长下进行梯度洗脱;建立1... 详细信息

[目的]建立桑叶超高效液相色谱(UPLC)指纹图谱,结合化学计量学与多成分含量测定综合评价不同产地桑叶药材质量。[方法]采用CORTECS UPLC C18色谱柱(2.1 mm×100 mm,1.6μm),以0.1%甲酸水-乙腈为流动相在350 nm波长下进行梯度洗脱;建立16批桑叶药材UPLC指纹图谱,并对指标成分进行含量测定;对指纹图谱进行相似度评价及主成分分析,利用偏最小二乘法-判别分析寻找不同产地桑叶药材的差异性成分。[结果]桑叶药材指纹图谱共标定出14个共有峰,通过比对标准对照品,指认出其中8个,分别为新绿原酸、绿原酸、咖啡酸、隐绿原酸、芦丁、异槲皮苷、山奈酚-3-O-芸香糖苷和紫云英苷;16批药材相似度均大于0.962,主成分分析将16批桑叶药材分为三类,偏最小二乘法-判别分析筛选出5个差异性标志物,差异显著性排序为1号峰(新绿原酸)>4号峰(隐绿原酸)>3号峰(咖啡酸)>14号峰>11号峰。[结论]建立的综合评价方法稳定、可靠,可为桑叶药材的质量评价研究提供理论依据。

关键词：桑叶超高效液相色谱指纹图谱化学计量学含量测定

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聚乳酸二醇及其聚氨酯的合成及性能研究

聚氨酯工业 2024年第3期39卷 15-19页

作者：许星海童敏杰张萍石慧子陈晓马博谋东华大学纺织学院上海201620 东华大学分析测试中心上海201620 东华大学纺织科技创新中心上海201620

以左旋乳酸(L-LA)单体为原料,分别与1,4-丁二醇(BDO)、1,6-己二醇(HDO)、1,12-十二烷二醇(DCO)进行酯化反应,合成了分子量约为1500 g/mol的聚乳酸二醇。通过傅里叶变换红外光谱(FT-IR)和核磁共振(1H-NMR)测试分析了聚乳酸二醇的结构,并... 详细信息

以左旋乳酸(L-LA)单体为原料,分别与1,4-丁二醇(BDO)、1,6-己二醇(HDO)、1,12-十二烷二醇(DCO)进行酯化反应,合成了分子量约为1500 g/mol的聚乳酸二醇。通过傅里叶变换红外光谱(FT-IR)和核磁共振(1H-NMR)测试分析了聚乳酸二醇的结构,并采用自动电位滴定仪测定了羟值及酸值。以聚乳酸二醇为软段,六亚甲基二异氰酸酯(HDI)和扩链剂BDO为硬段,采用溶液法合成了一系列聚乳酸聚氨酯,并采用FT-IR、凝胶渗透色谱、差示扫描量热仪、热重分析以及拉伸测试等对聚氨酯的结构与性能进行表征。结果表明,随着合成聚乳酸二醇所用的3种亚烷基二醇碳链长度的增加,聚乳酸聚氨酯材料的熔点从118℃降低到103℃,玻璃化转变温度从8℃降低到-8℃,断裂伸长率从154%增加到211%,其拉伸强度(在8 MPa左右)、模量和邵A硬度逐渐减小。

关键词：生物基聚氨酯聚乳酸聚氨酯聚乳酸二醇热塑性聚氨酯

On the National Fitness Strategy in the Context of Completing the Building a Moderately Prosperous Society in All Respects

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The Journal of Human Rights 2020年第5期19卷 587-602页

作者：徐翔 NIU huizi(译) Administrative Law School Northwest University of Political Science and Law Human Rights Research Institute Northwest University of Political Science and Law 不详

In the process of completing the building a moderately prosperous society in all respects,China has been paying increasing attention to the protection of human rights including various emerging human rights,with the human rights protection system in China being *** an integral part of sports rights,the national fitness strategy advocated and promoted by China is a manifestation of the importance attached to sports rights,one of the emerging human *** as an important part of sports rights,it not only has diversified institutional connotations,but is also an important measure for completing the building a moderately prosperous society in all *** has improved the quality and effectiveness of sports rights protection with the nationwide fitness strategy,expanded the idea for realizing sports rights with the"internet+National fitness"model,and driven the modernization of sports rights protection by means of intelligent national fitness *** practices reflect a holistic and institutionalized response to the national decision of completing the building a moderately prosperous society in all respects and have contributed to completing the all-round construction of a moderately well-off society in China.

关键词： moderately prosperous society national fitness sports rights human rights sports law

Three Categories of International Comments on National Human Rights Action Plans and Their Implications——An Analysis Based on UPR Reports

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The Journal of Human Rights 2020年第3期19卷 376-393页

作者：许尧 NIU huizi(译) Center for the Study of Human Rights at Nankai University (National Human Rights Education and Training Base) Zhou Enlai School of Government Nankai University 不详

At least 57 countries have formulated and implemented 78 national human rights action plans, and the international assessment of them has had direct influence on their international human rights images of their issuers and the focuses of future planning According to related reports from the universal periodic review by the united nations Human rights Council, three categories of comments in a rough quantitative proportion of 1:4:2 have been made by the international community on these plans, which can be categorized as: Attention, Laudatory and expectation, representing objective attention, appreciation or encouragement and anticipation of further implementation or improvement, respectively In terms of regions, Asian countries have received the most Attention Comments, europe and Africa fewer, and America the least The marked achievements in the formulation and implementation of human rights action plans in China have attracted widespread attention and recognition, and further efforts should be made to implement steady and consistent human rights policies, improve the implementation mechanisms and integrate the external and internal functions of human rights action plans so as to promote the sustainable development of China’s human rights cause.

关键词： National Human Rights Action Plan UPR human rights diplomacy