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Potential morphological responses of an artificial beach to a flood in extreme events: field observation and numerical modelling

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Acta Oceanologica Sinica 2024年第7期43卷 78-92页

作者： Jiadong Fan Cuiping Kuang Xuejian Han Lixin Gong huixin liu Jiabo Zhang College of Civil Engineering Tongji UniversityShanghai 200082China The Eighth Geological Brigade Hebei Geological and Mineral Exploration Development BureauQinhuangdao 066001China Marine Ecological Restoration and Smart Ocean Engineering Research Center of Hebei Province Qinhuangdao 066001China

Conch Island is a typical artificial island at the Tanghe Estuary in Bohai Sea,*** improve natural environment and boost local tourism,beach nourishment will be applied to its north-western *** projected beach is landward and opposite to the Jinmeng Bay ***,with climate changes,frequent heavy rainfalls in Hebei Province rise flood hazards at the Tanghe *** this circumstance,potential influences on the projected beach of a flood are investigated for sustainable managements.A multi-coupled model is established and based on the data from field observations,where wave model,flow model and multifraction sediment transport model are *** addition,the impacts on the projected beach of different components in extreme events are discussed,including the spring tides,storm winds,storm waves,and sediment *** numerical results indicate the following result.(1)Artificial islands protect the coasts from erosion by obstructing landward waves,but rise the deposition risks along the target shore.(2)Flood brings massive sediment inputs and leads to scours at the estuary,but the currents with high sediment concentration contribute to the accretions along the target shore.(3)The projected beach mitigates flood actions and reduces the maximum mean sediment concentration along the target shore by 20%.(4)The storm winds restrict the flood and decrease the maximum mean sediment concentration by 21%.With the combined actions of storm winds and waves,the maximum value further declines by 38%.(5)A quadratic polynomial relationship between the deposition depths and the maximum sediment inputs with flood is established for estimations on the potential morphological changes after the flood process in extreme *** the uncertainty of estuarine floods,continuous monitoring on local hydrodynamic variations and sediment characteristics at Tanghe Estuary is necessary.

关键词： beach nourishment flood artificial island sediment transport extreme events storm

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RETINOBLASTOMA RELATED 1 switches mitosis to meiosis in rice

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Plant Communications 2024年第6期5卷 193-212页

作者： Yongjie Miao Hanli You huixin liu Yangzi Zhao Jiangzhe Zhao Yafei Li Yi Shen Ding Tang Baohui liu Kewei Zhang Zhukuan Cheng Guangdong Provincial Key Laboratory of Plant Adaptation and Molecular Design Innovative Center of Molecular Genetics and EvolutionSchool of Life SciencesGuangzhou UniversityGuangzhou 510006China Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Zhongshan Biological Breeding Laboratory/Key Laboratory of Plant Functional Genomics of the Ministry of Education Agricultural College of Yangzhou UniversityYangzhou 225009China State Key Laboratory of Plant Genomics Institute of Genetics and Developmental BiologyInnovation Academy for Seed DesignChinese Academy of SciencesBeijing 100101China Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants Department of BiologyCollege of Life SciencesZhejiang Normal UniversityJinhua 321004China Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops/Jiangsu Key Laboratory of Crop Genetics and Physiology Yangzhou UniversityYangzhou 225009China

The transition from mitosis to meiosis is a critical event in the reproductive development of all sexually reproducing ***,the mechanisms that regulate this process in plants remain largely ***,we find that the rice(Oryza sativa L.)protein RETINOBLASTOMA RELATED 1(RBR1)is essential to the transition from mitosis to *** of RBR1 function results in hyper-proliferative sporogenous-celllike cells(SCLs)in the anther locules during early stages of reproductive *** hyperproliferative SCLs are unable to initiate meiosis,eventually stagnating and degrading at late developmental stages to form pollen-free *** results suggest that RBR1 acts as a gatekeeper of entry into ***,cytokinin content is significantly increased in rbr1 mutants,whereas the expression of type-B response factors,particularly LEPTO1,is significantly *** the known close association of cytokinins with cell proliferation,these findings imply that hyper-proliferative germ cells in the anther locules may be attributed to elevated cytokinin concentrations and disruptions in the cytokinin *** a genetic strategy,the association between germ cell hyper-proliferation and disturbed cytokinin signaling in rbr1 has been *** summary,we reveal a unique role of RBR1 in the initiation of meiosis;our results clearly demonstrate that the RBR1 regulatory module is connected to the cytokinin signaling pathway and switches mitosis to meiosis in rice.

关键词： RETINOBLASTOMA RELATED1 meiosis initiation cytokinin rice

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Trends in Mortality of Cirrhosis in China: An Analysis of the China Death Surveillance Database from 2008 to 2020

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Journal of Clinical and Translational Hepatology 2024年第3期12卷 236-244页

作者： Xiaoxiao Wang huixin liu Jinlei Qi Lijun Wang Peng Yin Feng liu Lai Wei Yu Wang Maigeng Zhou Huiying Rao Peking University People’s Hospital Peking University Hepatology InstituteBeijing Key Laboratory of Hepatitis C and Immunotherapy for Liver DiseasesBeijing International Cooperation Base for Science and Technology on NAFLD DiagnosisBeijingChina Department of Clinical Epidemiology and Biostatistics Peking University People’s HospitalBeijingChina National Center for Chronic Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Beijing Tsinghua Changgung Hospital Tsinghua UniversityBeijingChina Chinese Foundation for Hepatitis Prevention and Control BeijingChina

Background and Aims:China accounts for 14.9%of total cirrhosis deaths worldwide.A detailed and comprehensive understanding of the contemporary status of cirrhosis mortality in China is crucial for establishing strategies for intervention and decreasing the disease burden of cirrhosis *** study aimed to report the cirrhosis mortality rates in our whole country or province over ***:Mortality data from 2008 to 2020 were retrieved from the Disease Surveillance Point System(DSPs)of the Chinese Center for Disease Control and *** crude mortality rate and age-standardized mortality rate of patients with cirrhosis were stratified by sex,residential location,and *** average annual percentage change(AAPC)in cirrhosis mortality rates from 2008 to 2020 was also ***:The crude mortality rate of cirrhosis was 4.57/100,000 people in *** with females and individuals living in urban areas,males and people living in rural areas had greater age-standardized *** crude mortality rate and age-standardized mortality rate in provinces in Southwest China(Guangxi,Yunnan,Guizhou,and Qinghai)were greater than those in other ***,with increasing age,the age-specific mortality rate increased *** 2008 to 2020,the mortality rate of cirrhosis in China decreased except for in males aged 50–59 years,females aged 45–49 years and females aged 80–84 ***:The mortality rate of patients with cirrhosis in China decreased from 2008 to *** the future,interventions of cirrhosis mortality control need to pay more attention to all males,females aged 45–49 and 80–84 years,and people living in rural areas and in provinces in Southwest China.

关键词： Cirrhosis Mortality Trend China

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Mortality Burden of Liver Cancer in China: An Observational Study From 2008 to 2020

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Journal of Clinical and Translational Hepatology 2024年第4期12卷 371-380页

作者： huixin liu Xiaoxiao Wang Lijun Wang Peng Yin Feng liu Lai Wei Yu Wang Maigeng Zhou Jinlei Qi Huiying Rao Department of Clinical Epidemiology and Biostatistics Peking University People's HospitalBeijingChina Peking University People’s Hospital Peking University Hepatology InstituteBeijing Key Laboratory of Hepatitis C and Immunotherapy for Liver DiseasesBeijing International Cooperation Base for Science and Technology on NAFLD DiagnosisBeijingChina National Center for Chronic Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Beijing Tsinghua Changgung Hospital Tsinghua UniversityBeijingChina Chinese Foundation for Hepatitis Prevention and Control BeijingChina

Background and Aims:China accounts for nearly half of liver cancer deaths globally.A better understanding of the current liver cancer mortality will be helpful to establishing priorities for intervention and to decreasing the disease burden of liver *** study aimed to explore and predict the mortality burden of liver cancer in ***:Data were extracted from the Disease Surveillance Point system of the Chinese Center for Disease Control and Prevention from 2008 to *** and age-standardized liver cancer mortality rates were reported by sex,urban or rural residence,and *** in liver cancer mortality rates from 2008 to 2020 were estimated as average annual percentage change(AAPC).The changing trend of live cancer mortality in the future is also ***:In 2020,the crude mortality of liver cancer was 25.57/100,000,and males and people lived in rural areas had higher age-standardized liver cancer mortality rates than females and people lived in people in urban *** mortality and age-standardized mortality rates in southwest provinces(Guangxi,Sichuan,Tibet)and in a northeast province(Heilongjiang)were higher than that in other provinces,and age-specific mortality rates increased with *** 2008 to 2020,liver cancer mortality rates decreased,but people under 50 years of age had a higher AAPC than those over 50 years of age,possibly because of the adoption of hepatitis B virus vaccination in newborns and ***,the mortality of liver cancer in 2021–2030 is predicted to have a downward ***:Liver cancer mortality rates declined in China from 2008 to *** interventions to control liver cancer mortality need to focus on people of male sex,older age,and living in rural areas or less developed provinces.

关键词： Liver cancer Mortality Burden Trend China Prediction

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基于校准窗口集成与耦合市场特征的可解释双层日前电价预测

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中国电机工程学报 2024年第4期44卷 1272-1285,I0003页

作者：刘慧鑫沈晓东魏泽涛刘友波刘俊勇白元宝四川大学电气工程学院四川省成都市610065 四川能投综合能源公司四川省成都市611130

随着电力市场之间耦合程度不断加深,只局限于单个市场内部的传统特征集不足以支撑高精度预测的需求。而且模型预测性能对校准窗口的选择敏感,而传统电价预测仅使用一个固定时间长度的数据集,同时预测模型的“黑盒”结构导致预测结果在... 详细信息

随着电力市场之间耦合程度不断加深,只局限于单个市场内部的传统特征集不足以支撑高精度预测的需求。而且模型预测性能对校准窗口的选择敏感,而传统电价预测仅使用一个固定时间长度的数据集,同时预测模型的“黑盒”结构导致预测结果在工程应用中可信度偏低。针对上述问题,该文提出一种考虑校准窗口集成与耦合市场特征的可解释双层日前电价预测框架。内层框架为基于改进自适应噪声完备集合经验模态分解(improved complete ensemble empirical mode decomposition,ICEEMDAN)的择优预测,首先分解原始电价序列,然后应用Lasso估计回归(lassoestimated autoregressive,LEAR)、长期和短期时间序列网络(long-term and short-term time-series networks,LSTNet)、卷积神经网络-长短记忆神经网络(convolutionalneuralnetworks-longshort termmemory,CNN-LSTM)、移动平均(autoregressive integrated moving average,ARIMA)和核极限学习机(kernel extreme learning machines,KELM)模型预测子序列并选择最优预测算法。外层框架为基于贝叶斯模型平均(bayes modelaveraging,BMA)的校准窗口集成预测,针对每个不同校准窗口长度数据集下的预测分配权重并集成得到预测电价。最后,通过可解释方法沙普利加性解释模型(shapley additiveexplanations,SHAP)分析耦合市场特征如何影响预测电价。该文通过北欧电力市场数据集的算例分析证明了所提算法的优越性和校准窗口集成方案的有效性。

关键词：校准窗口集成耦合市场特征双层预测框架改进自适应噪声完备集合经验模态分解(ICEEMDAN) 贝叶斯模型平均(BMA) 沙普利加性解释模型(SHAP)

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热机械处理对Al-Cu-Mg合金显微组织和力学性能的调控机理

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中国有色金属学报 2024年第1期34卷 50-62页

作者：王琮琳刘辉新郑亚亚王昆陈志国中南大学材料科学与工程学院长沙410083 湖南人文科技学院材料工程系娄底417000

采用X射线衍射仪(XRD)、透射电子显微镜(TEM)、拉伸力学性能测试以及疲劳裂纹扩展速率测试等手段探究热机械处理工艺对Al-Cu-Mg合金显微组织及宏观性能的影响。结果表明:热机械处理工艺可以使Al-Cu-Mg合金获得良好的强塑性配合,其中,采... 详细信息

采用X射线衍射仪(XRD)、透射电子显微镜(TEM)、拉伸力学性能测试以及疲劳裂纹扩展速率测试等手段探究热机械处理工艺对Al-Cu-Mg合金显微组织及宏观性能的影响。结果表明:热机械处理工艺可以使Al-Cu-Mg合金获得良好的强塑性配合,其中,采用25%变形量的固溶热轧+30%变形量的深冷非对称轧制(1.2异速比)+100℃、6 h的人工时效处理时,Al-Cu-Mg合金的伸长率可达10.1%;抗拉强度和屈服强度达到了517.2和448.3 MPa,分别比常规T6态的Al-Cu-Mg合金高74.8和98.6 MPa。热机械处理工艺使合金中出现大量位错缠结及细小S析出相,高强度的Goss织构和大量剪切织构通过影响疲劳裂纹的偏折提升合金的疲劳性能。

关键词： Al-Cu-Mg合金热机械处理拉伸力学性能显微组织疲劳裂纹扩展速率

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Prevalence and risk evaluation of cardiovascular disease in the newly diagnosed prostate cancer population in China:A nationwide,multi-center,population-based cross-sectional study

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Chinese Medical Journal 2024年第11期137卷 1324-1331页

作者： Weiyu Zhang huixin liu Ming liu Shi Ying Renbin Yuan Hao Zeng Zhenting Zhang Sujun Han Zhannan Si Bin Hu Simeng Wen Pengcheng Xu Weimin Yu Hui Chen Liang Wang Zhitao Lin Tao Dai Yunzhi Lin Tao Xu Department of Urology Peking University People’s HospitalBeijing 100044China Department of Clinical Epidemiology and Biostatistics Peking University People’s HospitalBeijing 100044China Department of Urology Beijing HospitalNational Center of GerontologyBeijing 100005China Institute of Geriatric Medicine Chinese Academy of Medical SciencesBeijing 100005China Department of Urology Wuhan Union HospitalHuazhong University of Science&TechnologyWuhanHubei 430022China Department of Urology The Third People’s Hospital of ChengduChengduSichuan 610014China Department of Urology West China Hospital of Sichuan UniversityChengduSichuan 610041China Department of Urologic Oncology Tianjin Medical University Cancer Institute&HospitalTianjin 300060China Department of Urology Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China National Cancer Center Beijing 100021China National Clinical Research Center for Cancer Beijing 100021China Department of Urology Liaoning Cancer HospitalShenyangLiaoning 110801China Department of Urology The Second Hospital of Tianjin Medical UniversityTianjin 300141China Tianjin Institute of Urology Tianjin Medical UniversityTianjin 300141China Department of Urology Lu’an Affiliated Hospital of Anhui Medical UniversityLu’anAnhui 237322China Department of Urology Renmin Hospital of Wuhan UniversityWuhanHubei 430060China Department of Urology Harbin Medical University Affiliated Cancer HospitalHarbinHeilongjiang 150081China Department of Urology The Second Hospital of Dalian Medical UniversityDalianLiaoning 116023China Department of Urology Surgery Fujian Cancer HospitalFuzhouFujian 350014China Department of Urology Surgery Hunan Cancer HospitalChangshaHunan 410031China Department of Urology Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian 350004China

Background:Cardiovascular disease(CVD)has emerged as the leading cause of death from prostate cancer(PCa)in recent decades,bringing a great disease burden *** with preexisting CVD have an increased risk for major adverse cardiovascular events when treated with androgen deprivation therapy(ADT).The present study aimed to explore the prevalence and risk evaluation of CVD among people with newly diagnosed PCa in ***:Clinical data of newly diagnosed PCa patients were retrospectively collected from 34 centers in China from 2010 to 2022 through convenience *** was defined as myocardial infarction,arrhythmia,heart failure,stroke,ischemic heart disease,and *** risk was estimated by calculating Framingham risk scores(FRS).Patients were accordingly divided into low-,medium-,and high-risk groups.χ2 or Fisher’s exact test was used for comparison of categorical ***:A total of 4253 patients were enrolled in the present study.A total of 27.0%(1147/4253)of patients had comorbid PCa and CVD,and 7.2%(307/4253)had two or more *** enrolled population was distributed in six regions of China,and approximately 71.0%(3019/4253)of patients lived in urban *** imaging and pathological evaluation,most PCa patients were diagnosed at an advanced stage,with 20.5%(871/4253)locally progressing and 20.5%(871/4253)showing *** of them initiated prostatectomy(46.6%,1983/4253)or regimens involving ADT therapy(45.7%,1944/4253)for prostate *** the present PCa cohort,43.1%(1832/4253)of patients had hypertension,and half of them had poorly controlled blood *** FRS stratification,as expected,a higher risk of CVD was related to aging and metabolic ***,we also found that patients with treatment involving ADT presented an originally higher risk of CVD than those without *** was in accordance with clinical practice,i.e.,aged patients or patients at advanced oncological stages were inclined to accept sys

关键词： Prostate cancer Castration Cardiovascular disease Prevalence Cardiovascular risk

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电热应力对硅油产气特性协同效应的实验研究

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高压电器 2024年第1期60卷 100-107,117页

作者：连鸿松郑东升刘慧鑫赖永华李长云国网福建省电力有限公司电力科学研究院福州350007 山东省科技大学山东青岛266590

实验室中常采用加速老化方法获得硅油的老化试样,并根据试样中溶解气体组分及体积分数判断硅绝缘油的老化状态,但当前实验中仅能施加热应力或电应力,不能较好地反映硅油的真实工况。为解决这这一问题,文中开展了电热应力对硅油产气特性... 详细信息

实验室中常采用加速老化方法获得硅油的老化试样,并根据试样中溶解气体组分及体积分数判断硅绝缘油的老化状态,但当前实验中仅能施加热应力或电应力,不能较好地反映硅油的真实工况。为解决这这一问题,文中开展了电热应力对硅油产气特性协同效应的实验研究。文中针对PMX-200型硅油,在200℃、25 kV下设计了硅油的热电老化、电热老化和电热联合老化等3组加速老化实验,通过对试样中的气体组分及体积分数分析,发现热电老化方式与电热联合老化方式下试样中溶解气体组分及体积分数最为接近,误差在7.41%~16.86%之间。文中结果表明实验中可用热电老化方式模拟硅油的实际老化条件。同时,文中结合ReaxFF力场,从原子水平上分析了硅油的热老化及电热老化机理。文中所得结论可为硅油的加速老化实验提供理论基础。

关键词：电硅绝缘油热电联合老化产气特征协同效应

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考虑海岸植被影响的水沙动力数学模型研究进展

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同济大学学报（自然科学版） 2024年第9期52卷 1418-1427页

作者：匡翠萍丛新韩雪健宫立新刘会欣朱磊同济大学土木工程学院上海200092 河北省地质矿产勘查开发局第八地质大队河北秦皇岛066000

介绍了植被模型的不同考虑方式,分别从水流阻力、床面阻力、植被消长等方面展开讨论。基于工程尺度和实验室尺度水沙动力数学模型的研究,综述了植被影响下的流速、紊动能、拟序结构,不同波浪形态的传播特征以及悬沙浓度、地形演变等相... 详细信息

介绍了植被模型的不同考虑方式,分别从水流阻力、床面阻力、植被消长等方面展开讨论。基于工程尺度和实验室尺度水沙动力数学模型的研究,综述了植被影响下的流速、紊动能、拟序结构,不同波浪形态的传播特征以及悬沙浓度、地形演变等相关的研究进展。结合大量数学模型研究,提出了未来的研究趋势。

关键词：海岸植被生态防护数学模型波流动力泥沙输运

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中小外卖平台动态定价与补贴策略研究

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中国物价 2024年第10期 5-12页

作者：刘会新徐雅娟郑州大学管理学院

推动外卖市场规范有序发展,除实施反垄断措施外,中小外卖平台通过竞争手段提升市场竞争力也非常关键。本文在实证调研的基础上,考虑补贴骑手和补贴商家两种模式,在平台不同战略(短期战略和长期战略)下构建双寡头两期动态博弈模型,用于... 详细信息

推动外卖市场规范有序发展,除实施反垄断措施外,中小外卖平台通过竞争手段提升市场竞争力也非常关键。本文在实证调研的基础上,考虑补贴骑手和补贴商家两种模式,在平台不同战略(短期战略和长期战略)下构建双寡头两期动态博弈模型,用于分析基础服务质量差异、用户忠诚度和用户补贴感知价值对中小平台定价与补贴策略的影响。研究发现:(1)高用户忠诚度可以缓解由基础服务质量差异带来的竞争劣势,提高第二期中小外卖平台定价能力和用户规模。(2)当用户补贴感知价值较高时,中小外卖平台实施补贴策略能够有效扩大用户规模,提升定价能力和利润水平。(3)在补贴有效的情形下,当用户补贴程度低于某一特定阈值时,中小外卖平台应优先选择补贴商家;一旦补贴程度超过该阈值,则应转向补贴骑手。这一临界补贴决策点随基础服务质量差异的增加而后移,随用户忠诚度和用户补贴感知价值的增加而前移;当补贴程度达到第二个特定阈值时,最优补贴策略再次发生转变,重新回归为补贴商家。不同的是,该决策点随用户忠诚度的增加而后移。值得注意的是,两期定价与补贴策略和平台战略无关。

关键词：中小外卖平台动态定价策略补贴策略用户忠诚度用户补贴感知价值

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