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Improving strength-ductility synchronously of Electron beam welded Ti600/Ti2AlNb joint through isothermal forging

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Progress in Natural Science:Materials International 2024年第3期34卷 532-539页

作者： Yongqiang Zhang Xiangyi Xue Guoming Zheng Jingli Zhang huiming Li Shewei Xin State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi'an Qin Ti Intelligent Manufacturing Technologies Co.Ltd. Northwest Institute for Nonferrous Metal Research Xi'an University of Science and Technology Avic Xi'an Aircraft Industry Group Company Ltd.

Different alloys can be flexibly combined to meet the performance needs of different parts of the compressor disc by welding process. However, achieving a good combination of dissimilar alloys with different mechanical properties has always been a research difficulty. In this work, a Ti600/Ti2AlNb joint was fabricated through electron beam welding and an isothermal forging was used to optimized its microstructure and mechanical performance. The isothermal forging process increases the ultimate tensile strength（UST） and yield strength（YS）of the Ti600/Ti2AlNb joint by ～18 %, while ～2.5 times the ductility. It is indicated that before forging, the Ti600/Ti2AlNb joint exhibits a much lower strength than that of Ti600 matrix, whereas the opposite is true after isothermal forging. The isothermal forging broken the coarse columnar grains of Ti600/Ti2AlNb joint and render to an equiaxed B2 structure in which the acicular α2and O phase are precipitated, resulting a synchronous enhancement of strength and ductility. This work may pave an effective routine for improving the comprehensive mechanical properties of dissimilar metal welding joint.

关键词： Electron beam welding Isothermal forging Mechanical performance Ti600/Ti2AlNb joint

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万历初期宫廷财政视角下的张居正改革

故宫博物院院刊 2019年第2期 62-74,109页

作者：王慧明东北师范大学历史文化学院

史学界历来认为张居正改革在一定程度上挽救了晚明危机,抑制宫廷消费是其财政改革的内容之一。翻检《明神宗实录》,从明神宗即位到万历十四年,大致是张居正实施改革与其死后被清算的历史过程,通过宫廷财政重新审视张居正改革,既没有在... 详细信息

史学界历来认为张居正改革在一定程度上挽救了晚明危机,抑制宫廷消费是其财政改革的内容之一。翻检《明神宗实录》,从明神宗即位到万历十四年,大致是张居正实施改革与其死后被清算的历史过程,通过宫廷财政重新审视张居正改革,既没有在撙节宫廷消费上取得成功,也没有养成明神宗的俭德,宫廷财政的恶性膨胀在张居正死后走向新高峰。

关键词：明神宗张居正改革万历初年宫廷财政

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功能梯度球形水凝胶的化学力学耦合分析

力学学报 2019年第4期51卷 1054-1063页

作者：杨健鹏王惠明浙江大学工程力学系杭州310027 浙江大学浙江省软体机器人与智能器件研究重点实验室杭州310027

作为一种新型智能材料,水凝胶具有特殊的化学力学耦合性能.采用功能梯度形式可使得水凝胶具有更好的适应性和可调控性.本研究中假设交联密度沿径向按幂函数规律变化,并基于水凝胶的大变形多场耦合一般理论,采用Flory-Huggins自由能函数... 详细信息

作为一种新型智能材料,水凝胶具有特殊的化学力学耦合性能.采用功能梯度形式可使得水凝胶具有更好的适应性和可调控性.本研究中假设交联密度沿径向按幂函数规律变化,并基于水凝胶的大变形多场耦合一般理论,采用Flory-Huggins自由能函数,建立了功能梯度球形水凝胶在球对称情形的控制方程,并开展了功能梯度球形水凝胶在给定内压和化学势情行的非均匀大变形溶胀行为的理论研究.计算结果表明,不同梯度指数的球形水凝胶的内压、内孔半径曲线和内压、内表面径向伸长率曲线均呈现出一段稳定区间和另一段不稳定区间,说明内压超出某临界值会发生失稳并导致水凝胶的最终破坏.内压的临界值随梯度指数的增大而增大.研究表明,功能梯度球形水凝胶的材料参数(梯度指数、亲疏水特性、交联密度和溶剂分子的体积)和环境化学势对水凝胶溶胀行为具有重要的影响.在给定内表面压力的情况下,功能梯度球形水凝胶内表面的径向位移随梯度指数的改变接近为线性变化,而随其他参数的影响都呈现出明显的非线性.本研究有助于实现水凝胶智能结构和器件在复杂条件下的精准调控.

关键词：功能梯度水凝胶化学力学耦合溶胀行为大变形球对称

Potential biomarkers for diagnosis and disease evaluation of idiopathic pulmonary fibrosis

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Chinese Medical Journal 2023年第11期136卷 1278-1290页

作者： Qing wang Zhaoliang Xie Nansheng Wan Lei Yang Zhixian Jin Fang Jin Zhaoming Huang Min Chen huiming wang Jing Feng Department of Respiratory and Critical Care Medicine Tianjin Medical University General HospitalTianjin 300052China Department of Respiratory and Critical Care Medicine of Kunming Municipal First People’s Hospital KunmingYunnan 650000China Respiratory Department of Sanming Yong’an General Hospital SanmingFujian 366000China

Idiopathic pulmonary fibrosis(IPF)is a chronic progressive lung disease characterized by progressive lung fibrogenesis and histological features of usual interstitial *** has a poor prognosis and presents a spectrum of disease courses ranging from slow evolving disease to rapid deterioration;thus,a differential diagnosis remains *** biomarkers have been identified to achieve a differential diagnosis;however,comprehensive reviews are *** review summarizes over 100 biomarkers which can be divided into six categories according to their functions:differentially expressed biomarkers in the IPF compared to healthy controls;biomarkers distinguishing IPF from other types of interstitial lung disease;biomarkers differentiating acute exacerbation of IPF from stable disease;biomarkers predicting disease progression;biomarkers related to disease severity;and biomarkers related to *** used for the diagnosis of IPF included serum,bronchoalveolar lavage fluid,lung tissue,and ***-specific biomarkers are of great clinical value for the differential diagnosis of ***,the physiological measurements used to evaluate the occurrence of acute exacerbation,disease progression,and disease severity have *** physiological measurements with biomarkers may increase the accuracy and sensitivity of diagnosis and disease evaluation of *** biomarkers described in this review are not routinely used in clinical *** large-scale multicenter studies are required to design and validate suitable biomarker panels that have diagnostic utility for IPF.

关键词： Alveolar epithelial cell dysfunction Biomarker Diagnosis Fibrogenesis Extracellular matrix remodeling Idiopathic pulmonary fibrosis Immune dysfunction

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面向5G的短包物理层安全通信

中国科学：信息科学 2021年第9期51卷 1507-1523页

作者：冯晨王慧明西安交通大学信息与通信工程学院西安710049 智能网络与网络安全教育部重点实验室西安710049

无线短包通信是实现海量机器类通信(massive machine type communication,m MTC)和超可靠低延迟通信(ultra-reliable low latency communication,uRLLC)等5G物联网(Internet of Things,IoT)应用的关键技术之一.面向工业物联网、车联网等应用,无线通信的安全问题至关重要.本文从物理层安全角度研究了慢衰落信道下短包通信系统的安全传输.基于安全短包通信信息论结论定义了保密中断概率(secrecy outage probability,SOP),并以SOP约束下的可靠吞吐量作为短包通信系统的安全通信性能指标.在此基础上设计了自适应和非自适应编码传输方案,分别利用合法信道的精确/部分瞬时信道状态信息(channel state information,CSI)进行编码速率设计及传输门限优化以最大化吞吐量,并进一步分析了主要系统参数对最优吞吐量的影响.数值结果验证了传输方案的有效性,并验证了SOP约束下主要系统参数对系统安全传输性能的影响.

关键词：短包通信物理层安全保密中断概率传输方案设计性能评估

On the Robust Control of Compliantly Actuated Robots With Mismatched Disturbances

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On the Robust Control of Compliantly Actuated Robots With Mi...

第37届中国控制会议

作者： huiming wang Meihua Ke Qinggao Lu Qingdu Li Chongqing Key Laboratory of Complex Systems and Bionic Control and Key Laboratory of Industrial Internet of Things & Networked ControlMinistry of EducationChongqing University of Posts and Telecommunications Key Laboratory of Measurement and Control of Complex Systems of Engineering Ministry of EducationSoutheast University

In this paper,we describe a general control framework for output reference trajectory tracking of compliantly actuated robots in the presence of time-varying *** order to obtain strong robustness and attenuate chattering,a continuous sliding mode control（CSMC） design is ***,this CSMC structure can not guarantee the high tracking performance of the closed loop system since exiting mismatched time-varying disturbances in compliantly actuated *** to the significance of dealing with the mismatched problem,a new sliding surface with the assistance of generalized proportional integral observers（GPIOs）,which only use the position measurement of the motor and link,is designed such that system states can be driven to equilibrium ***,under this proposed general control framework,called the CSMC+GPIO scheme,the robustness of compliant robot systems is further enhanced since matched disturbance estimation is used to ***,a detailed stability analysis of the closed loop system under the proposed approach is *** results are provided to illustrate the promised position tracking performance of the proposed control strategy under the different test conditions.

关键词： Sliding mode control(SMC) generalized proportional integral observer(GPIO) compliant actuator mismatched disturbance disturbance attenuation

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明代募兵制发展中的卫所舍余

古代文明 2020年第2期14卷 115-124,M0006页

作者：王慧明东北师范大学历史文化学院吉林长春130024

召募卫所舍余是明代募集兵员的途径之一。明初舍余在卫所制的组织内拥有相对的自由空间,其中一些人为了获取世袭武职和报酬,具有从军的意愿,这是募兵制能够在具有身份强制性的卫所体系中得以发展的社会心理基础。召募卫所舍余随着土木... 详细信息

召募卫所舍余是明代募集兵员的途径之一。明初舍余在卫所制的组织内拥有相对的自由空间,其中一些人为了获取世袭武职和报酬,具有从军的意愿,这是募兵制能够在具有身份强制性的卫所体系中得以发展的社会心理基础。召募卫所舍余随着土木之变后大规模募兵制的展开,九边、京师等地皆有施行,与抽选并行。召募舍余补充正军和顶种军屯起到缓解卫所制废弛的作用。然而随着政府加强对舍余的控制,该群体在卫所组织内的自由空间缩小,人身束缚趋于强化,不再具有应募的自由身份,其兵役在弘治以后逐渐以抽选为主。

关键词：明代卫所舍余募兵制

Exact Analysis of Functionally Graded Piezoelectric Hollow Spheres with Exponentially Varying Properties

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Narciclasine induces colon carcinoma cell apoptosis by inhibiting the IL-17A/Act1/TRAF6/NF-kB signaling pathway

中国力学学会学术大会'2009

作者： wang huiming Department of Mechanics,Zhejiang University, Hangzhou 310027,China,

An exact solution is obtained for radially polarized functionally graded piezoelectric(FGP)hollow spheres under spherically symmetric deformation. The material properties are assumed to be represented by an exponentia... 详细信息

关键词： exact solution piezoelectricity functionally graded material hollow sphere exponentially graded

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Genes & Diseases 2024年第5期11卷 428-441页

作者： huiming Deng Qiang Liu Siman Yu Lifan Zhong Lianfang Gan Huiquan Gu Qianru wang Ruxin Cheng Yong Liu Li Liu Ling Huang Ronghua Xu Department of Gastrointestinal Surgery Huazhong University of Science and Technology Union Shenzhen HospitalShenzhenGuangdong 518000China Research Center for Drug Safety Evaluation of Hainan Province HaikouHainan 571199China Department of Pharmacology Hainan Medical UniversityHaikouHainan 571199China Department of Pathology Guangzhou Panyu Central HospitalGuangzhouGuangdong 511400China Hainan Province Key Laboratory for Drug Preclinical Study of Pharmacology and Toxicology Research Hainan Medical UniversityHaikouHainan 571199China Hainan Center for Drug and Medical Device Evaluation and Service Hainan Medical Products AdministrationHaikouHainan 570216China

IL-17 A is a promoter of colorectal cancer initiation and *** is a polyhydroxy alkaloid compound isolated from Narcissus plants,which has potent anti-inflammatory and antitumor *** effects of narciclasine on colorectal tumors were evaluated,with a focus on IL-17 *** reduced the growth of HCT-116 and SW-480 colon cancer cells in vitro and in vivo in murine *** results of flow cytometry on JC-1 and Annexin V/PI revealed that narciclasine significantly reduced the mitochondrial membrane potential and induced apoptosis,findings confirmed by western blotting results of reduced Bcl2 and enhanced Bax expression,as well as accumulation of cleaved Caspase-3,Caspase-8,Caspase-9,and cytoplasmic *** narciclasine incubation,IL-17 A,Act1,and TRAF6 were down-regulated,while p-P65(Ser536)accumulated in the cytoplasm,a finding confirmed by laser scanning confocal ***17A substitution could partly reverse these narciclasine effects while they were elevated by IL17A ***,IL-17 A,Act1,and TRAF6 were significantly expressed to greater extents in human colorectal cancer compared to normal adjacent tissue specimens and were closely linked with a poor *** study provided evidence that narciclasine may be a useful therapeutic drug for colorectal cancer treatment through its actions in down-regulating the L-17A/Act1/TRAF6/NF-kB anti-apoptotic signaling pathway.

关键词： Act1 Apoptosis Colonrectal cancer IL-17A Narciclasine NF-kB