检索结果-南通市图书馆

Direct van der Waals epitaxial growth of 1D/2D Sb2Se3/WS2 mixed-dimensional p-n heterojunctions

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Nano Research 2019年第5期12卷 1139-1145页

作者： Guangzhuang Sun Bo Li Jia Li Zhengwei Zhang huifang Ma Peng Chen Bei Zhao Ruixia Wu Weiqi Dang Xiangdong Yang Xuwan tang Chen Dai Ziwei Huang Yuan Liu Xidong Duan Xiangfeng Duan State Key Laboratory for Chemo/Biosensing and Chemometrics and Hunan Key Laboratory of Two-Dimensional Materials College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China Department of Applied Physics School of Physics and ElectronicsHunan UniversityChangsha 410082China Department of Chemistry and Biochemistry University of CaliforniaLos AngelesCalifornia 90095USA

The mixed-dimensional integration of two-dimensional (2D) materials with non-2D materials can give rise to prominent advances in performance or *** date,the mixed-dimensional one-dimensional (1D)/2D heterostructures have been fabricated using various physical assembly ***,direct epitaxial growth method which has notable advantages in preparing large-scale products and obtaining perfect interfaces is rarely ***,we demonstrate for the first time the direct synthesis of the 1D/2D mixed-dimensional heterostructures by sequential vapor-phase growth of Sb2Se3 nanowires on WS2 monolayers.X-ray diffraction (XRD) pattern and Raman spectrum confirm the composition of the Sb2Se3/NS2 *** electron microscope (TEM) measurement demonstrates high quality of the *** transport characterization reveals that Sb2Se3 nanowire exhibits p-type characteristic and that WS2 monolayer exhibits n-type behavior,and that the p-n diode from 1D/2D mixed-dimensional Sb2Se3/WS2 heterostructure possesses obvious current rectification *** measurements of the heterostructures show apparent photovoltaic response with an open-circuit voltage of 0.19 V,photoresponsivity of 1.51 A/W (Vds =5 V) and fast response time of less than 8 *** van der Waals epitaxial growth mode of Sb2Se3 nanowires on WS2 monolayers is verified by stripping the Sb2Se3 nanowire from the heterostructures using ***,the direct van der Waals epitaxy opens a facile pathway to 1D/2D mixed-dimensional heterostructures for functional electronic and optoelectronic devices.

关键词： van der Waals epitaxy Sb2Se3/WS2heterostructures rectification behavior photovoltaic effect photoswitch

基于嵌入式技术的全自动电梯控制柜电磁兼容检测控制系统设计

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

控制与信息技术 2024年第2期 94-98页

作者：宋来军王会方倪敏敏卢东李晓露唐海龙孙丹丹南京市特种设备安全监督检验研究院江苏南京211800

针对目前电梯控制柜电磁兼容检测方法智能化程度低、操作繁琐且缺乏电梯系统状态监测的问题,文章设计了一套电梯控制柜电磁兼容检测控制系统。其构建了“上位机+下位机”的控制系统架构,开发了基于ARM的嵌入式控制器,设计了自动检测流... 详细信息

针对目前电梯控制柜电磁兼容检测方法智能化程度低、操作繁琐且缺乏电梯系统状态监测的问题,文章设计了一套电梯控制柜电磁兼容检测控制系统。其构建了“上位机+下位机”的控制系统架构,开发了基于ARM的嵌入式控制器,设计了自动检测流程和控制系统上下位机应用软件,使电梯控制柜具备传感器信号采集、CAN总线通信等功能,实现了控制柜电磁兼容性能化检测的以及电梯系统状态的实时监测。使用该系统对电梯控制柜进行传导抗扰度、电压暂降、电压中断、电快速瞬变脉冲群检测和浪涌试验,并对传感器信号异常、电源故障和通信异常故障进行模拟试验,结果显示,该电梯控制柜电磁兼容检测控制系统运行稳定、数据采集准确、操作简单,且对各种故障类型均能准确、高效识别。该系统可以满足电梯生产厂家及检测机构的电磁兼容检测需求,且与以往检测方法相比,减少约67%的检测人力投入。

关键词：电梯控制柜电磁兼容自动检测嵌入式控制器 CAN总线

Clinical observation of Yiqi Qingdu Prescription(益气清毒方)on the treatment of intermediate-stage and advanced non-small-cell lung cancer

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2021年第2期41卷 308-315页

作者： LIANG Qijun tang Xiaoling YU Jiong XIONG Monian ZHU huifang XIONG Linkai ZENG Ru YU Peiwen Department of Respiratory Affiliated Hospital of Jiangxi University of Traditional Chinese MedicineNanchang 330006China Department of Oncology Affiliated Hospital of Jiangxi Institute of Traditional Chinese MedicineNanchang 330046China Key Laboratory of Yiqi Qingdu for Malignant Tumor Jiangxi Institute of Traditional Chinese MedicineNanchang 330046China School of clinical medicine Jiangxi University of Traditional Chinese MedicineNanchang 330004China Second Department of Internal Medicine Jiangxi Tumor HospitalNanchang 330029China

OBJECTIVE:To observe the effects of the Yiqi Qingdu prescription(益气清毒方)on intermediate-stage and advanced non-small-cell lung cancer(NSCLC).METHODS:In total,300 patients with intermediate-stage or advanced NSCLC were randomly and equally divided into three groups using computer-generated random numbers as follows:Western medicine(WM),Chinese medicine(CM),and integrated Traditional Chinese and Western Medicine(IM).After 3 months of treatment,the overall response rate(ORR);disease control rate(DCR);symptom score(SS);Karnofsky performance status(KPS);adverse event score;counts of CD3^(+),CD4^(+),and CD8^(+)cells;CD4^(+)/CD8^(+)ratio;and carcinoembryonic antigen(CEA)level were compared among the ***:The ORRs were 30.36%,20.24%,and 7.87%in the IM,CM,and WM groups,respectively,whereas the DCRs were 85%,75%,and 73%,*** to the CM group,the ORR was significantly higher in the WM and IM groups,whereas the DCR was significantly higher in the IM group(all P<0.05).SS was obviously higher in the WM group than in the other two groups(both P<0.01).KPS was significantly lower in the WM group after treatment(P=0.005).The mean number of adverse events was significantly lower in the CM(2.2±1.3)and IM(2.4±1.3)groups than in the WM group(4.6±1.7,both P<0.05).CD3^(+)cell counts were significantly decreased in the WM group(P=0.031).In the IM group,CD8^(+)cell counts were increased after treatment,whereas the CD4^(+)/CD8^(+)ratio was decreased(both P<0.01).Compared with the WM group,CD3^(+)(P=0.01),CD4^(+)(P=0.044),and CD8^(+)(P=0.009)cell counts were significantly higher in the IM group,whereas the CD4^(+)/CD8^(+)ratio was significantly lower(P=0.011).Relative to the CM group,CD8^(+)cell counts were significantly higher(P=0.001)and the CD4^(+)/CD8^(+)ratio was significant ly lower in the IM group(P=0.001).CEA levels were significantly increased in the CM group(P=0.023).CONCLUSION:The Yiqi Qingdu prescription can improve the outcomes of WM in patients with NSCLC

关键词： carcinoma,non-small-cell lung integrative medicine therapeutic uses carcinoembryonic antigen antigens,differentiation,T-lymphocyte Yiqi Qingdu prescription

Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2020年第1期11卷 1-22页

作者： Si Wang Zheying Min Qianzhao Ji Lingling Geng Yao Su Zunpeng Liu huifang Hu Lixia Wang Weiqi Zhang Keiichiro Suzuiki Yu Huang Puyao Zhang Tie-Shan tang Jing Qu Yang Yu Guang-Hui Liu Jie Qiao Department of Obstetrics and Gynecology Center for Reproductive MedicinePeking University Third HospitalBeijing 100191China National Laboratory of Biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Advanced Innovation Center for Human Brain Protection National Clinical Research Center for Geriatric DisordersXuanwu Hospital Capital Medical UniversityBeijing 100053China Institute for Stem cell and Regeneration Chinese Academy of SciencesBeijing 100101China Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China Beijing Institute for Brain Disorders Beijing 100069China Institute for Advanced Co-Creation Studies Osaka UniversityOsaka 560-8531Japan Graduate School of Engineering Science Osaka UniversityOsaka 560-8531Japan Department of Medical Genetics School of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China

Cockayne syndrome(CS)is a rare autosomal recessive inherited disorder characterized by a variety of clinical features,including increased sensitivity to sunlight,progressive neurological abnormalities,and the appearance of premature ***,the pathogenesis of CS remains unclear due to the limitations of current disease ***,we generate integration-free induced pluripotent stem cells(iPSCs)from fibroblasts from a CS patient bearing mutations in CSB/ERCC6 gene and further derive isogenic genecorrected CS-iPSCs(GC-iPSCs)using the CRISPR/Cas9 ***-associated phenotypic defects are recapitulated in CS-iPSC-derived mesenchymal stem cells(MSCs)and neural stem cells(NSCs),both of which display increased susceptibility to DNA damage *** aging defects in CS-MSCs are rescued by the targeted correction of mutant *** next map the transcriptomic landscapes in CS-iPSCs and GC-iPSCs and their somatic stem cell derivatives(MSCs and NSCs)in the absence or presence of ultraviolet(UV)and replicative stresses,revealing that defects in DNA repair account for CS ***,we generate autologous GC-MSCs free of pathogenic mutation under a cGMP(Current Good Manufacturing Practice)-compliant condition,which hold potential for use as improved biomaterials for future stem cell replacement therapy for ***,our models demonstrate novel disease features and molecular mechanisms and lay a foundation for the development of novel therapeutic strategies to treat CS.

关键词： Cockayne syndrome CRISPR/Cas9 gene correction disease modelling mesenchymal stem cell neural stem cell

High-performance asymmetric electrodes photodiode based on Sb/WSe2 heterostructure

在线全文

学校读者我要写书评

暂无评论

Nano Research 2019年第2期12卷 339-344页

作者： Xiao Liu Guangzhuang Sun Peng Chen Junchi Liu Zhengwei Zhang Jia Li huifang Ma Bei Zhao Ruixia Wu Weiqi Dang Xiangdong Yang Chen Dai Xuwan tang Zhuojun Chen Lili Miao Xingqiang Liu Bo Li Yuan Liu Xidong Duan Department of Applied Physics School of Physics and Electronics Hunan University Changsha 410082 China State Key Laboratory for Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China

Two-dimensional (2D) van der Waals (vdWs) metal-semiconductor heterostructures with atomically sharp interface and matched work functions have recently attracted great attention due to their unique electronic and optoelectronic properties. Here we report the vapor phase epitaxial growth of large-scale vertical Sb/WSe2 metal-semiconductor vdWs heterostructures with uniform stacking orientation. Compared with the growth on S1O2/S1 substrate, the thick ness of Sb nan osheet on WSe2 can be reduced effectively to mono layer. We con struct Sb-WSe2-Au asymmetric electrodes photodiode based on the Sb/WSe2 heterostructures. Electrical transport measurements indicate that the photodiode show obvious rectifying effect. Optoelectronic characterizations show prominent photoresponse with a high photoresposivity of 364 mA/W, a fast response time of less than 8 ms, a large open-circuit voltage of 0.27 V and a maximum electrical power output of 0.11 nW. The direct growth of high-quality metal-semiconductor vdWs heterostructures may open up new realms in 2D functional electronics and optoelectronics.

关键词： two-dimensional asymmetric electrode photodiode van der Waals (vdWs) heterostructure optoelectronics

miRNA与子宫内膜异位症不孕关系的研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

广西医学 2024年第9期46卷 1423-1427页

作者：林桂娇周金宵栾毅峰丛慧芳唐静怡向艳丹黄书煜潘彦卉王琴黑龙江中医药大学研究生院黑龙江省哈尔滨市150040 黑龙江中医药大学附属第二医院妇科一病房黑龙江省哈尔滨市150010

子宫内膜异位症(EMT)是一种常见的妇科疾病,可引起女性不孕。EMT不孕对女性身心健康造成极大威胁,了解该病的发病机制有利于指导早期疾病干预,改善患者预后,甚至有可能帮助患者恢复正常生育能力。目前,EMT不孕的具体发病机制尚不明确。... 详细信息

子宫内膜异位症(EMT)是一种常见的妇科疾病,可引起女性不孕。EMT不孕对女性身心健康造成极大威胁,了解该病的发病机制有利于指导早期疾病干预,改善患者预后,甚至有可能帮助患者恢复正常生育能力。目前,EMT不孕的具体发病机制尚不明确。研究表明,miRNA与EMT之间存在关联。本文就miRNA与EMT不孕的关系进行综述,为该病的早期诊断及治疗提供参考。

关键词：子宫内膜异位症不孕症微小RNA 基因调控综述

Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb,Polygonum multiflorum

在线全文

学校读者我要写书评

暂无评论

Frontiers of Medicine 2021年第2期15卷 330-332页

作者： Chunyu Li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao Ruiyu Li Can Tu huifang Li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa tang Yun Zhu Jinjie Li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang China Military Institute of Chinese Medicine 302 Military HospitalBeijing 100039China Institute of Medicinal Plant Development Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100193China Integrative Medical Center 302 Military HospitalBeijing 100039China Beijing Friendship Hospital Capital Medical UniversityBeijing 100050China Diagnosis and Treatment Center for Non-infectious Diseases 302 Military HospitalBeijing 100039China Beijing Union University Beijing 100101China Shanxi University of Traditional Chinese Medicine Taiyuan 030619China

Erratum to Frontiers of Medicine 201711(2):253–265 https://***/10.1007/s11684-017-0508-9 The original version of this article unfortunately contained some *** panel of“LPS–/drug–”in Fig.3B(Page 259),the panels of“LPS–/EtoAc+”and“LPS–/Residue+”in Supplementary Fig.3(Page 7 in the online supplementary materials)should be *** authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.

关键词： Medicine hepato corrected

提升水稻上植保无人机喷施药液沉积效果的关键因素

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

农学学报 2024年第5期14卷 16-23页

作者：张永强李思洁刘桔葛百一唐子晴蒲小明林壁润杨祁云沈会芳张景欣广东省农业科学院植物保护研究所/广东省植物保护新技术重点实验室广州510640 广东供销绿色农产品生产供应基地运营有限公司广东惠州516166 仲恺农业工程学院农业与生物学院广州510225 广东烟草韶关市有限公司广东韶关512029

旨在解决植保无人机在水稻上施药后存在雾滴分布不均、农药沉积率不高等实际田间作业问题,比较分析了飞防助剂、施药液量、飞行速度对植保无人机在水稻上施药后雾滴分布和农药沉积率的影响,明确可产生显著性差异的关键因素,进一步分析... 详细信息

旨在解决植保无人机在水稻上施药后存在雾滴分布不均、农药沉积率不高等实际田间作业问题,比较分析了飞防助剂、施药液量、飞行速度对植保无人机在水稻上施药后雾滴分布和农药沉积率的影响,明确可产生显著性差异的关键因素,进一步分析该因素是否影响农药混配药液的微粒物理性质和润湿性能。结果表明:在三因素三水平的正交试验中,不同试验处理在上层收集的雾滴的面积显著大于中层和下层,加入助剂促使试验处理在不同高度上的雾滴分布较为均匀,它们在中、下层收集的雾滴的面积占比明显得到提高;飞防助剂、施药液量和飞行速度可不同程度地影响农药沉积率,农药沉积率范围在43.72%~68.63%;体现3个因素对农药沉积率影响程度的R值分别为13.44、6.25和4.93,其中仅飞防助剂产生的差异达显著性水平;在药液混配后0~48 h内,加入2种不同助剂均可显著降低其表面张力和静态接触角,加入2种不同助剂的药液之间则未表现显著差异;此外,呈现较高农药沉积率的助剂品种则可同时有效降低药液在混配后0~48 h内的粒径大小和粒径分散程度。研究结果对于植保无人机在水稻上的精准施药技术提升具有重要参考依据,可以提高农药沉积率,减少农药流失。

关键词：植保无人机水稻雾滴分布农药沉积率助剂

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

早期应用多重益生菌对早产儿的影响

河南医学研究 2024年第5期33卷 818-821页

作者：王军王茹张宇航宋娟徐发林董慧芳夏磊曹洋洋张含唐晓康郭倩玉郑州大学第三附属医院儿科河南郑州450052 河南省儿科疾病临床医学研究中心河南郑州450052

目的分析出生后早期应用多重益生菌对早产儿临床并发症尤其是坏死性小肠结肠炎(NEC)发生的预防作用及对智力发育的影响。方法选择2022年2月至2023年2月于郑州大学第三附属医院住院治疗的120例胎龄0.05);试验组月龄6个月时智能发育评分... 详细信息

目的分析出生后早期应用多重益生菌对早产儿临床并发症尤其是坏死性小肠结肠炎(NEC)发生的预防作用及对智力发育的影响。方法选择2022年2月至2023年2月于郑州大学第三附属医院住院治疗的120例胎龄0.05);试验组月龄6个月时智能发育评分高于对照组(P<0.05)。试验组全程未发现不良反应。结论早产儿出生后早期应用多重益生菌是安全有效的,可以促进早产儿的智力发育,降低早产儿NEC全阶段发病率,但不能降低NEC发生的严重程度。

关键词：益生菌早产儿坏死性小肠结肠炎智力发育