检索结果-南通市图书馆

椎间孔镜下腰椎间盘切除术后早期复发危险因素分析

在线全文

学校读者我要写书评

暂无评论

浙江创伤外科 2024年第3期29卷 416-418,422页

作者：罗坚鲍军国邱惠斌张峰浙江省宁波市杭州湾医院宁波315336 浙江省宁波市第二医院

目的探讨椎间孔镜下腰椎间盘切除术后早期复发危险因素并进一步分析上述指标风险预测效能。方法回顾性纳入2019年6月至2023年2月于本院及上级医院行椎间孔镜下腰椎间盘切除术治疗腰椎间盘突出症患者共132例,根据术后随访6个月有无复... 详细信息

目的探讨椎间孔镜下腰椎间盘切除术后早期复发危险因素并进一步分析上述指标风险预测效能。方法回顾性纳入2019年6月至2023年2月于本院及上级医院行椎间孔镜下腰椎间盘切除术治疗腰椎间盘突出症患者共132例,根据术后随访6个月有无复发分为复发组(12例)和未复发组(120例);比较复发组和未复发组临床特征资料,并将证实有统计学意义指标纳入Logistics回归模型,评估椎间孔镜下腰椎间盘切除术后早期复发独立危险因素;描绘受试者工作特征(ROC)曲线评估上述独立危险因素用于椎间孔镜下腰椎间盘切除术后早期复发预测临床效能。结果 132例术后随访6个月内复发12例,复发率为9.09%;术后中位复发时间为69.0(7.0,158.0) d。两组椎间盘退变Pfirrmann分级情况、突出部位显著极外侧比例、Modic病变严重程度情况、椎间盘高度指数、突出物基底部宽度、术后纤维环破口水平及椎间孔面积比较差异有统计学意义(P<0.05)。Logistic回归模型多因素分析结果显示,突出基底部宽度增加、Modic病变程度加重及椎间孔面积缩小均是椎间孔镜下腰椎间盘切除术后早期复发独立危险因素(P<0.05)。ROC曲线分析结果显示,突出基底部宽度、Modic病变程度及椎间孔面积均可用于椎间孔镜下腰椎间盘切除术后早期复发风险预测,且上述指标联合预测效能显著优于单一指标及两两联合(P<0.05)。结论椎间孔镜下腰椎间盘切除术后早期复发与突出基底部宽度增加、Modic病变程度加重及椎间孔面积缩小均密切相关;同时上述指标联合在预测椎间孔镜下腰椎间盘切除术后早期复发风险方面显示出更佳临床效能。

关键词：椎间孔镜腰椎间盘突出手术复发危险因素

Integrating the second near-infrared fluorescence imaging with clinical techniques for multimodal cancer imaging by neodymiumdoped gadolinium tungstate nanoparticles

在线全文

学校读者我要写书评

暂无评论

Nano Research 2021年第7期14卷 2160-2170页

作者： Xujiang Yu Aodenggerile Zhao Jiang Jianliang Shen Zhiqiang Yan Wanwan Li huibin qiu Joint Research Center for Precision Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital South CampusSouthern Medical University Affiliated Fengxian HospitalShanghai 201499China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesState Key Laboratory of Metal Matrix CompositeShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Ophthalmology Optometry and Vision ScienceSchool of Ophthalmology and OptometrySchool of Biomedical EngineeringWenzhou Medical UniversityWenzhou 325027China Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325001China

Second near-infrared(NIR-II)fluorescence imaging is a recently emerged technique and is highly useful for accurate diagnosis of *** a diverse array of fluorescent nanomaterials have been developed to enable NIR-II fluorescence in various situations,they normally fail to unify the clinical techniques,such as computed tomography(CT)and magnetic resonance imaging(MRI).Therefore,exploiting multimodal agents to integrate the newly emerged NIR-II fluorescence and traditional clinical techniques would be of key ***,we report a rational fabrication of neodymium(Nd)-doped gadolinium tungstate nanoparticles(NPs)that are subsequentially decorated with a hydrophilic layer and demonstrate that they can achieve the harmonious integration of NIR-II fluorescence imaging,CT,and *** NIR-II fluorescence emission was activated by an incident light with discrete wavelength ranging from 250 to 810 ***-II fluorescence-CT-MRI associated trimodal imaging was subsequently demonstrated for breast cancer by an 808 nm laser,along with the estimation of NIR-II fluorescence imaging for cervical *** integration of newly emerged and traditional clinical imaging techniques highlights the huge potential of rare-earth-doped NPs for multimodal imaging of different types of cancer.

关键词： rare-earth-doped nanoparticles(NPs) second near-infrared fluorescence multimodal imaging cancer

Tailored boron phosphate monolithic foam with multimodal hierarchically porous structure and its applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2022年第7期15卷 6695-6704页

作者： qiuwen Liu Qiang Liu Yawei Wu Renyou Zeng Fangshu Xing ChuChu Cheng huibin qiu Caijin Huang State Key Laboratory of Photocatalysis on Energy and Environment College of ChemistryFuzhou UniversityFuzhou 350116China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou 341000China

The synthesis of multimodal hierarchically porous materials is of great challenge by facile ***,we assemble BPO_(4) hollow spheres into macroscopic foam materials with multimodal hierarchically porous structure by combining down-to-up process and Ostwald ripening *** monolithic B_(2)O_(3)@BPO_(4) foams were obtained from a sticky hydrogel precursor by a one-step annealing *** foam has the self-supporting frame of BPO_(4) hollow spheres with covering B_(2)O_(3) nanowires and shows excellent permeability and relatively high surface area due to hierarchical *** formation mechanism of monolithic B_(2)O_(3)@BPO_(4) foams mainly undergoes inflation,particle aggregation,and Ostwald ripening *** foams exhibit superior catalytic activity in oxidation dehydrogenation of alkanes due to the sufficient exposure of active sites over the special frame ***,various monolithic functionalized BPO_(4) foam composites can be easily synthesized and exhibit superior performance in different applications including the oxidation of carbon monoxide,and the self-driven removal of organic *** interestingly,we also found the sticky hydrogel precursor possesses good heat shielding *** work provides a new insight for constructing multimodal hierarchically porous materials with the remaining superior property of nanoscale to cope with various challenges.

关键词： multimodal hierarchically porous materials tailored monolithic foam sticky hydrogel self-supporting hollow spheres

Tunable Multicolor Circularly Polarized Luminescence via Co-assembly of One Chiral Electron Acceptor with Various Donors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2023年第7期5卷 1592-1601页

作者： Fang Wang Chengshuo Shen Fuwei Gan Guoli Zhang huibin qiu School of Chemistry and Chemical Engineering Zhangjiang Institute for Advanced StudyFrontiers Science Center for Transformative MoleculesState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240 Key Laboratory of Specially Functional Polymeric Materials and Related Technology(Ministry of Education) School of Material Science and EngineeringEast China University of Science and TechnologyShanghai 200237

Chiroptical materials with multicolor and signinvertible circularly polarized luminescence(CPL)are important for advanced optical devices and display ***,a general strategy is developed to generate CPL with highly tunable emission bands and handedness through charge-transfer(CT)complexation and co-assembly of one chiral non-emissive tetranitrofluorene-based acceptor with various achiral purple to blue emissive *** resulting assemblies exhibit intense CPL with a rich array of colors(519-668 nm)and prominent dissymmetry factors(|glum|)in the range of 10^(-3)-10^(-2).Notably,the CPL sign can be readily inverted by slightly changing the molecular structure of achiral ***-crystal analysis reveals that the donor and acceptor molecules are alternately and asymmetrically packed in a lamellar fashion through CT interactions,leading to efficient transfer of ***,the refined packing is mediated by the intensity and manner of CT interactions,rendering an inversion of *** chiral co-assembly not only occurs for planar achiral donor molecules,but is also accessible to nonplanar conjugated molecules such as[4]helicene ***,the CPL feature of the resulting products can be easily and broadly manipulated,aiming at advanced chiroptical systems.

关键词： circularly polarized luminescence charge transfer chirality co-assembly supramolecular chemistry

Tunable construction of transition metal-coordinated helicene cages

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2021年第12期32卷 3988-3992页

作者： Yongle Ding Chengshuo Shen Fuwei Gan Jinghao Wang Guoli Zhang Lingling Li Mouhai Shu Bangshang Zhu Jeanne Crassous huibin qiu School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China Instrumental Analysis Center Shanghai Jiao Tong UniversityShanghai 200240China Univ Rennes Institut des Sciences Chimiques de RennesUMR CNRS 6226Campus de BeaulieuRennes 35042France

We report a facile and tailored method to prepare globally twisted chiral molecular cages through tunable coordination of bis-bipyridine-terminated helicene ligands to a series of transition metals including Fe(Ⅱ), Co(Ⅱ), Ni(Ⅱ) and Zn(Ⅱ). This system shows an efficient remote transfer of stereogenecity from the helicene core to the bipyridine-metal coordination sites and subsequently the entire cages. While the Fe(Ⅱ), Co(Ⅱ) and Ni(Ⅱ)-derived M_(2)L_(3)(M for metal and L for ligand) cages exhibit quasi-reversible redox features, the Zn(Ⅱ) analogues reveal prominent yellow circularly polarized luminescence. Interestingly,with the addition of Na_(2)SO_(4), the Zn_(2)L_(3)cages reassemble into sextuple-stranded Zn_(6)L_(6)(SO_(4))_(4)cages in which three Zn_(2)L_(2) units are bound together by four sulfates and further coalesced by offset inter-ligandπ-π interactions.

关键词： Helicene Coordination cage Chiral Global helicity Circularly polarized luminescence

Helical Conformation Tunability via Hydrogen Bonding in Supramolecular Frameworks

在线全文

学校读者我要写书评

暂无评论

CCS Chemistry 2022年第4期4卷 1405-1413页

作者： Zhijie Xue Fuwei Gan Hong Liu Chengshuo Shen huibin qiu Bo Yang Ping Yu School of Physical Science and Technology ShanghaiTech University201210 Shanghai School of Chemistry and Chemical Engineering State Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong University200240 Shanghai

Hydrogen-bonded molecules and their dynamics are significantly important in chemistry and biology due to their widespread *** their natural abundance and diversity,applications of molecules with dynamic conformations in artificial networks allow information storage and molecular motor design on the nanometer ***,we report hydrogen-bonded molecular networks with tunable helical conformation on metal *** dynamics of helical conformation in two-dimensional hydrogenbond networks are triggered and resolved by scanning probe microscopy at the single-molecule *** combinationwith theoretical calculations,the surfacespecific hydrogen bonds are identified as the origin of the dynamic helical *** results provide a distinctive access to molecular architecture with tunable helical conformation driven by hydrogenbond interaction on surfaces.

关键词： scanning probe microscope dynamic conformation hydrogen bond molecular frameworks DFT calculation

π-共轭纤维状杂化纳米结构的精准构筑与功能化

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

功能高分子学报 2020年第4期33卷 316-319页

作者：邱惠斌上海交通大学化学化工学院上海200240

π-共轭聚合物因在电致发光材料、场效应晶体管等领域具有潜在的应用前景而受到人们的广泛关注。通过π-共轭聚合物的可控组装实现纳米纤维结构的精确构筑一直是提升材料性能的研究方向和挑战之一。近来,中国科学院上海有机化学研究所... 详细信息

π-共轭聚合物因在电致发光材料、场效应晶体管等领域具有潜在的应用前景而受到人们的广泛关注。通过π-共轭聚合物的可控组装实现纳米纤维结构的精确构筑一直是提升材料性能的研究方向和挑战之一。近来,中国科学院上海有机化学研究所黄晓宇、冯纯课题组将非共价作用与活性结晶驱动自组装相结合,实现了多组分和多功能的以π-共轭对苯撑乙烯撑寡聚物(OPV)为核的纤维状杂化纳米结构的精确构筑及选择性功能化。利用“自晶种”(self-seeding)和活性“种子增长”(seeded growth)制备了以OPV为核,不同壳层的三嵌段和五嵌段单分散纳米纤维,并实现了对纤维各个嵌段长度的控制。利用聚2-乙烯基吡啶(P2VP)壳层作为后功能化锚点,可将无机纳米粒子(CdTe量子点、Au、Ag和Fe3O4纳米粒子)、聚合物球形胶束、SiO2/TiO2层负载在纤维状胶束的P2VP壳层中,并可单独对含有不同壳层的多嵌段纤维状胶束的P2VP壳层进行选择性修饰。这为多组分和多功能的π-共轭杂化纳米纤维状结构的高效构筑提供了一条新途径。

关键词： π-共轭聚合物自组装杂化纤维纳米粒子

在线全文

学校读者我要写书评

暂无评论

超高荧光量子产率圆偏振发光纳米石墨烯

有机化学 2023年第1期43卷 371-372页

作者：干富伟邱惠斌上海交通大学化学化工学院上海200240

圆偏振发光(circularly polarized luminescence,CPL)材料在三维显示、光学信息存储和加密、不对称合成、光电器件等方面具有广阔的应用前景,近年来已成为前沿研究的一个热点[1].衡量CPL材料性能优劣通常有两个关键参数,一个是荧光量子... 详细信息

圆偏振发光(circularly polarized luminescence,CPL)材料在三维显示、光学信息存储和加密、不对称合成、光电器件等方面具有广阔的应用前景,近年来已成为前沿研究的一个热点[1].衡量CPL材料性能优劣通常有两个关键参数,一个是荧光量子产率(ΦF),另一个是发光不对称因子(glum).在实际研究中,CPL材料的ΦF和|glum|通常情况下是无法兼顾的,很少有材料可以同时具有高ΦF和高|glum|.手性纳米石墨烯是一类具有非平面手性共轭结构的纳米石墨烯,在手性光学、电磁学等方面拥有其他传统手性分子可能无法具备的优势性能[2]。

关键词：不对称合成不对称因子偏振发光手性分子电磁学荧光量子产率三维显示光电器件

Supramolecular Photochirogenesis with Cyclodextrin-Silica Composite. Enantiodifferentiating Photocyclodimerization of 2-Anthrancenecarboxylate with Mesoporous Silica Wall-Capped γ--Cyclodextrin

在线全文

学校读者我要写书评

暂无评论

Supramolecular Photochirogenesis with Cyclodextrin-Silica Co...