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Sarcopenia adversely impacts clinical outcomes in patients undergoing pancreaticoduodenectomy: A systematic review and meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1857-1870页

作者： qi-hui zhang Jin-Dong Ma Yan-Min Lu Run-Nan zhang Zhong-Hua Zhao Ya-Tong Li qiang-Pu Chen Department of Clinical Nutrition Binzhou Medical University HospitalBinzhou 256603Shandong ProvinceChina Department of Hepatobiliary Surgery Binzhou Medical University HospitalBinzhou 256603Shandong ProvinceChina

BACKGROUND Sarcopenia is a syndrome marked by a gradual and widespread reduction in skeletal muscle mass and strength,as well as a decline in functional ability,which is associated with malnutrition,hormonal changes,chronic inflammation,distur-bance of intestinal flora,and exercise *** is a com-monly employed clinical intervention for conditions such as pancreatic head cancer,ampulla of Vater cancer,and cholangiocarcinoma,among others,with a notably high rate of postoperative *** is frequent in patients undergoing ***,data regarding the effects of sarcopenia in patients undergoing pancreaticoduodenectomy(PD)are both limited and *** PubMed,Cochrane Library,Web of Science,and Embase databases were screened for studies published from the time of database inception to June 2023 that described the effects of sarcopenia on the outcomes and complications of *** researchers independently assessed the quality of the data extracted from the studies that met the inclusion ***-analysis using RevMan 5.3.5 and Stata 14.0 software was *** and funnel plots were used,respectively,to demonstrate the outcomes of the sarcopenia group vs the non-sarcopenia group after PD and to evaluate potential publication *** Sixteen studies encompassing 2381 patients were included in the *** patients in the sarcopenia group(n=833)had higher overall postoperative complication rates[odds ratio(OR)=3.42,95%confidence interval(CI):1.95-5.99,P<0.0001],higher Clavien-Dindo class≥Ⅲ major complication rates(OR=1.41,95%CI:1.04-1.90,P=0.03),higher bacteremia rates(OR=4.46,95%CI:1.42-13.98,P=0.01),higher pneumonia rates(OR=2.10,95%CI:1.34-3.27,P=0.001),higher pancreatic fistula rates(OR=1.42,95%CI:1.12-1.79,P=0.003),longer hospital stays(OR=2.86,95%CI:0.44-5.28,P=0.02),higher mortality rates(OR=3.17,95%CI:1.55-6.50,P=0.002),and worse overall survival(hazard ratio=2.81,95%CI:1.4

关键词： Pancreaticoduodenectomy Sarcopenia Postoperative complications Length of stay Meta-analysis

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Synthesis of an Azobenzene-containing Main-chain Crystalline Polymer and Photodeformation Behaviors of Its Supramolecular Hydrogen-bonded Fibers

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Chinese Journal of Polymer Science 2020年第1期38卷 37-44,I0006页

作者： Zheng-Zheng Wang hui-qi zhang State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials (Ministry of Education) Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) and College of Chemistry Nankai University

The synthesis of a new azobenzene(azo)-containing main-chain crystalline polymer with reactive secondary amino groups in its backbone and photodeformation behaviors of its supramolecular hydrogen-bonded fibers are described. This main-chain azo polymer(namely Azo-MP6) was prepared via first the synthesis of a diacrylate-type azo monomer and its subsequent Michael addition copolymerization with trans-1,4-cyclohexanediamine under a mild reaction condition. Azo-MP6 was found to have a linear main-chain chemical structure instead of a branched one, as verified by comparing its ~1H-NMR spectrum with that of the azo polymer prepared via the polymer analogous reaction of AzoMP6 with acetic anhydride. The thermal stability, phase transition behavior, and photoresponsivity of Azo-MP6 were characterized with TGA,DSC, POM, XRD, and UV-Vis spectroscopy. The experimental results revealed that it had good thermal stability, low glass transition temperature,broad crystalline phase temperature range, and highly reversible photoresponsivity. Physically crosslinked supramolecular hydrogen-bonded fibers with good mechanical properties and a high alignment order of azo mesogens were readily fabricated from Azo-MP6 by using the simple melt spinning method, and they could show "reversible" photoinduced bending under the same UV light irradiation and good anti-fatigue properties.

关键词： Main-chain azobenzene polymer Crystalline polymer Michael addition polymerization Physically crosslinked network Photodeformation

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Unsupervised Multi-Expert Learning Model for Underwater Image Enhancement

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IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 708-722页

作者： Hongmin Liu qi zhang Yufan Hu hui Zeng Bin Fan the School of Intelligence Science and Technology and the Institute of Artificial Intelligence University of Science and Technology BeijingBeijing 100083China the School of Automation and Electrical Engineering University of Science and Technology BeijingBeijing 100083China IEEE

Underwater image enhancement aims to restore a clean appearance and thus improves the quality of underwater degraded *** methods feed the whole image directly into the model for ***,they ignored that the R,G and B channels of underwater degraded images present varied degrees of degradation,due to the selective absorption for the *** address this issue,we propose an unsupervised multi-expert learning model by considering the enhancement of each color ***,an unsupervised architecture based on generative adversarial network is employed to alleviate the need for paired underwater *** on this,we design a generator,including a multi-expert encoder,a feature fusion module and a feature fusion-guided decoder,to generate the clear underwater ***,a multi-expert discriminator is proposed to verify the authenticity of the R,G and B channels,*** addition,content perceptual loss and edge loss are introduced into the loss function to further improve the content and details of the enhanced *** experiments on public datasets demonstrate that our method achieves more pleasing results in vision *** metrics(PSNR,SSIM,UIQM and UCIQE) evaluated on our enhanced images have been improved obviously.

关键词： Multi-expert learning underwater image enhancement unsupervised learning

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Regulation of solvation structure and the cooperation environment of potassium bonds for wider-temperature adaptive potassium storage

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Rare Metals 2024年第4期43卷 1610-1621页

作者： Bing-Bing Liu Yi-hui Liu You-Bin zhang Zhen-Guo qi Guo-hui qin State Key Laboratory Base for Eco-Chemical Engineering College of Chemical EngineeringQingdao University of Science and TechnologyQingdao266042China Shandong Synergetic Innovation Center of Ecological and Chemical Engineering Qingdao266042China

Antimony selenide(Sb_(2)Se_(3))is one of the perspective candidates for potassium-ion batteries due to its advanced virtues stem including featured high capacity,fertile reserves and the relative narrow band *** the unique advantages,it is still plagued by the unstable interface compatibility and poor wider-temperature *** optimization of microstructure and the construction of inorganic-organic hybrids with a low desolvation barrier and rapid kinetics behaviors are efficient to address these *** Sb_(2)Se_(3)nanorods enclosed by the S-doped carbon layer(SC),further crosslinked by the poly(N-isopropylacrylamide)(PM)film(PM@Sb_(2)Se_(3)@SC),were artificially fabricated,and it displays the enrichment ion aggregated model as well as contacted ion pair state,the well-tailored cooperation environment of potassium bonds,assuring a homogeneous potassium deposition and an excellent widertemperature *** complicated experimental studies and theoretical calculations authenticate the synergistic effects of geometric conformation and compositional design for the tremendously enhanced potassium ***,the full device over PM@Sb_(2)Se_(3)@SC anode and the potassium Prussian blue cathode manifests impressively durable cycling life and wider-temperature adaptability,verifying the glorious contribution from the finely manipulation in solvation structure and potassium bonds to enhancing the potassium storage behaviors.

关键词： Anode Sb_(2)Se_(3) rods Interface compatibility Inorganic-organic electrode Potassium ion battery

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Effect of Different Protein Levels on Nutrient Digestion Metabolism and Serum Biochemical Parameters in Calves

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Agricultural Sciences in China 2008年第3期7卷 375-380页

作者： LI hui DIAO qi-yu zhang Nai-feng TU Yan WANG Ji-feng Feed Research Institute Chinese Academy of Agricultural Sciences Beijing 100081 P.R.China

The current study has been performed to examine the effects of different dietary protein levels on the growth, nutrient digestion and absorption, as well as biochemical parameters in calves. Nine healthy newborn calves were selected, randomly divided into 3 groups and fed 3 milk replacers with different protein levels （18, 22, and 26%）, respectively. Five period-digestion-metabolism trials were taken between 12-20, 22-30, 32-40, 42-50, and 52-60 days after birth. All 3 groups showed a similar growth curve during 11 to 61 experimental days, however, the growth rate of the 22% crude protein （CP） group was 8.89% higher than that of the 18% CP group and 19.48% higher than that of the 26% CP group, respectively. The apparent digestibility of dry material （DM） declined gradually with age, whereas, the apparent digestibility of N, extract ether （EE） rose slightly. Compared to the 22% CP and 26% CP group, calves fed with 18% CP apparently had a lower digestibility than DM, EE, and nitrogen （N）. The average apparent digestibilities of N were 69.39, 75.36, and 74.55%, respectively. Both the apparent digestibility and retention of calcium （Ca） and phosphorus （P） were steady throughout the experiment, but the average apparent digestibility of P in the 26% CP group was only 63.83%, which was markedly lower than that of the 18% CP group （70.40%） and 22% CP group （69.73%）. In addition, the serum concentrations of total protein （TP）, albumin （ALB）, and globulin （GLOB） of the 22% CP group were higher than those in the 18% CP and 26% CP groups. The urea N （BUN） content in the 18% CP group, on the other hand, was significantly lower than that of the other two groups. The highest glucose （GLU） concentration was found in the 22% CP group （5.38 mmol L^-1）, at the end of the trials. The protein levels in the milk replacer affected the digestion metabolism of nutrition and the serum biochemical parameters of calves at different physiological phases. Calves fed with 22% CP milk replacer had

关键词： calves protein levels milk replacer apparent digestibility biochemical parameters

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Anti-hepatoma Effect of DC2.4 Cells Transfected with Tumor-Associated Antigen Cdc25C In Vitro

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Current Medical Science 2022年第3期42卷 491-497页

作者： Chun-mei LI Yan-fei LI Lin TIAN qi-hui zhang Fang-yuan ZHENG Fa-rong MO School of Basic Medical Science Guangxi Medical UniversityNanning 530021China Laboratory of Hepatobiliary and Pancreatic Surgery Affiliated Hospital of Guilin Medical UniversityGuilin 541001China Guangxi Colleges and Universities Key Laboratory of Human Development and Disease Research Guangxi Medical UniversityNanning 530021China

Objective Cell division cyclin 25 homolog C(Cdc25C)is a tumor-associated antigen candidate gene,and this may be used as an effective target in cancer *** present study aims to evaluate the lysis effect of cytotoxic T lymphocytes(CTLs)induced by dendritic cell line DC2.4 overexpressing Cdc25C,and the feasibility of Cdc25C as a component in hepatoma *** The mouse Cdc25C gene was ligated into a lentiviral vector,and transfected into DC2.4 *** DC2.4 cell phenotype and cytokine secretion were determined by flow cytometry and ELISA,***8^(+)T cells were sorted from the spleens of C57BL/6 mice using a magnetic bead sorting kit obtained from Miltenyi Biotech,Germany,and co-cultured with DC2.4 cells for one week as effector ***,IL-2,granzyme B and perforin were detected in the CTL culture medium by ***,time-resolved fluorescence immunoassay was used to detect the immune killing effect of Cdc25C-specific CTLs on target ***,the effect of blocking MHC-I sites on target cells with a monoclonal anti-MHC-I antibody was *** The results revealed that Cdc25C could be stably overexpressed in DC2.4 cells by LV-Cdc25C ***2.4 cells transfected with LV-Cdc25C secreted more IL-6,IL-12,TNF-αand IFN-γ,and had higher expression levels of CD40,CD86,CCR7 and MHC-II than unaltered DC2.4 *** elevated Cdc25C in dendritic cells also further increased the secretion of IL-2,granzyme B and perforin to elicit Cdc25C-specific CTLs,and induced the higher cytotoxicity in Hepa1-6 cell lines(P<0.05),but this had no effect on the target cells when MHC-I monoclonal antibodies were *** DC2.4 cells transfected with LV-Cdc25C can induce specific CTLs,and result in a strong cellular immune *** dendritic cells that overexpress Cdc25C may be useful for hepatoma immunotherapy.

关键词： dendritic cells cell division cyclin 25 homolog C cytotoxic T lymphocytes hepatocellular carcinoma anti-hepatoma

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A Single-Fluorophore Multicolor Molecular Sensor That Visually Identifies Organic Anions Including Phosphates

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CCS Chemistry 2024年第3期6卷 774-782页

作者： Zezhou Zong qi zhang Da-hui Qu Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237

Developing fluorescent sensors for small-molecule phosphates offers opportunities in optically detecting biorelevant reactions and ***,it remains elusive how to identify phosphates from other anions,such as carboxylates and sulfates,because current synthetic phosphate receptors lack *** we report the construction of a multicolor fluorescent sensor that can identify phosphates from other analogous *** key design principle is to take advantage of the highly sensitive conformation-dependent emissive wavelength of diphenyl-9,14-dihydrodibenzo[a,c]phenazine fluorophores to sense the minor structural differences between phosphates and other anions,for example,sulfates and *** effect of structural factors such as spacer length and urea versus thiourea has been investigated by comparing the optical properties and binding affinities with the phosphate *** strategy provides a simple and robust fluorescent sensing solution to optically analyze small-molecule phosphates with antiinterference performance.

关键词： fluorescent sensors photoluminescence host-guest chemistry supramolecular chemistry noncovalent bonds

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Regio-and Stereoselective Polymerization of Bio-based Ocimene by Rare-Earth Metal Catalysts

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Chinese Journal of Polymer Science 2024年第2期42卷 223-229,I0008页

作者： qi-Yuan Wang Li-Peng Sang Zhen zhang Yang Jiang hui Tian Xia Zhao Xiang Guo Shi-hui Li State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei230026China Science and Technology on Aerospace Chemical Power Laboratory Hubei Institute of Aerospace ChemotechonologyXiangyang441003China Shanxi Coal Chemical Industry Technology Research Institute Xi’an710000China Hubei Institute of Aerospace Chemotechonology Xiangyang441003China

Coordination polymerization of renewable β-ocimene has been investigated using asymmetric diiminophosphinate lutetium complex1, β-diketiminate yttrium complex 2, bis(phosphino)carbazolide yttrium complex 3, half-sandwich benzyl fluorenyl scandium complex 4 and pyridyl-methylene-fluorenyl rare-metal complexes 5a–5c. Complexes 1, 4 and 5a–5c show trans-1,2-regioselectivities and high activities, of which 5c exhibits excellent isoselectivity(mmmm>99%). Conversely, complexes 2 and 3 promote β-ocimene polymerization to produce isotactic cis-1,4-polyocimenes(cis-1,4>99%, mm>95%). Diblock copolymers cis-1,4-PIP-block-cis-1,4-POc and cis-1,4-PBD-block-cis-1,4-POc are obtained in one-pot reactions of β-ocimene with isoprene and butadiene using complex 3. Epoxidation and hydroxylation of polyocimene afford functionalized polyolefins with enhanced T_(g)(from-20 ℃ to 79 ℃ and 74 ℃) and hydrophilicity.

关键词： Biobased monomer Terpenes Ocimene Rare-earths Polymerization Regio/stereoselectivity Elastomer

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MXene-derived quantum dots based photocatalysts:Synthesis,application,prospects,and challenges

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Chinese Chemical Letters 2024年第6期35卷 123-133页

作者： Hao Deng Yuxin hui Chao zhang qi Zhou qiang Li Hao Du Derek Hao Guoxiang Yang qi Wang School of Environmental Science and Engineering Zhejiang Gongshang UniversityHangzhou 310018China Instrumental Analysis Center of Zhejiang Gongshang University Hangzhou 310018China Centre for Technology in Water and Wastewater(CTWW) School of Civil and Environmental EngineeringUniversity of Technology Sydney(UTS)UltimoNSW 2007Australia

In recent years,the emerging two-dimensional material-MXenes has attracted widespread attention in the field of photocatalysis due to its high conductivity,suitable Fermi level,tunable elemental composition,and excellent photoelectric *** zero-dimensional quantum dots(MQDs)derived from 2D MXenes not only inherit the characteristics of MXenes but also exhibit better performance due to the quantum size *** on the above excellent physical and chemical properties,MQDs are often used as co-catalysts of photocatalysts,and show excellent co-catalytic *** the same time,compared with other cocatalysts(precious metals,metal oxides,metal sulfides),it has the advantages of low cost and high ***,understanding the status of MQDs in the field of photocatalysis is crucial for their further *** this review,we summarized the synthesis and modification methods of MQDs in recent years,as well as their photocatalytic applications in H_(2) production,CO_(2) reduction,N_(2) fixation,pollutant degradation,and other *** addition,the challenges and prospects faced by MQDs are also proposed,providing theoretical guidance for the further development of MQD-based photocatalysts.

关键词： MXenes Quantum dots Photocatalysis Composites Environment purification

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Recent advances in multifunctional shape memory photonic crystals and practical applications

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Nano Research 2024年第1期17卷 79-96页

作者： Yong qi Shufen zhang State Key Laboratory of Fine Chemicals Frontier Science Center for Smart MaterialsDalian University of TechnologyDalian 116024China

Shape memory photonic crystals(SMPCs)are smart composite materials with changeable structural color integrated by shape memory polymer and photonic *** can produce one or more temporary shapes through nanoscale deformation,memorizing current *** can be recovered to their original shapes or some intermediate states under external stimuli,accompanied by the variation of structural *** porous carriers with built-in sensing properties,SMPCs promoted the interdisciplinary development of nanophotonic technology in materials science,environmental engineering,biomedicine,chemical engineering,and ***,the recent progress on multifunctional SMPCs and practical applications,including traditional and cold programmable SMPCs,is summarized and *** primary concern is shape programming at the nanoscale that has demonstrated numerous attractive functions,including smart sensing,ink-free printing,solvent detection,reprogrammable gradient wetting,and controllable bubble transportation,under variations of the surface *** aims to figure out the nanoscale shape memory effects on structural color conversion and additional performance,inspiring the fabrication of the next generation of ***,perspectives on future research directions and applications are also *** is believed that multifunctional SMPCs are powerful nanophotonic tools for the interdisciplinary development of numerous disciplines in the future.

关键词： photonic crystal shape memory structural color cold programmable shape recovery

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