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Revisiting intrinsic brittleness and deformation behavior of B2 NiAl intermetallic compound: A first-principles study

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Journal of Materials Science & Technology 2018年第4期34卷 620-626页

作者： hui Xing Anping Dong Jian Huang Jiao Zhang Baode sun Shanghai Key Lab of Advanced High-temperature Materials and Precision Forming Shanghai Jiao Tong University State Key Laboratory of Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Collaborative Innovation Center for Advanced Ship and Deep-sea Exploration Shanghai Jiao Tong University State Key Lab of Metal Matrix Composites Shanghai Jiao Tong University

For NiAI intermetallic compound with B2 structure, there is still no calculation combining models of sin- gle and multiple layers while using the same basic set. Furthermore, some recently proposed criteria for brittleness and toughness have not been used to analyze its deformation behavior. Thus, first-principles calculation was applied to comprehensively study the elastic properties, ideal strength, generalized stacking fault energy and surface energy of B2-NiA1 intermetallic compound. The results suggest that calculations based on the current basic set give more accurate lattice parameters and elastic moduli. The Pugh criterion and Cauchy pressure cannot be used to interpret the intrinsic brittleness of NiAI. In comparison, the ductility parameter based on the strain energy under elastic instability and ZCT and Rice criteria based on generalized stacking fault energy and surface energy successfully identify the intrinsic brittleness of the NiA1 intermetallic compound. The reason why [111] slip always occurs in the defor- mation along [100] direction was clarified by examining the critical value for brittle-ductile transition. The results of density of state indicate shear deformation has less impact on structural stability, and the change of charge density difference implies that 〈001〉 shear induces more intensive redistribution of charge density, which is well correlated to the brittleness and deformation behavior of NiAI intermetallic comnound.

关键词： Intermetallics Mechanical properties Computer simulation

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长链非编码RNAKCNK15-AS1靶向微RNA-140-5p对骨关节炎软骨细胞增殖、凋亡及炎症因子表达的影响

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中华骨与关节外科杂志 2024年第5期17卷 459-466页

作者：孙鹏张国华陈超斌刘彬陈美周一林杨翾武汉市普仁医院骨关节外科武汉430081

目的:探讨长链非编码RNA(lncRNA)KCNK15-AS1是否通过靶向微RNA-140-5p(miR-140-5p)影响骨关节炎(OA)软骨细胞增殖、凋亡,炎症因子表达及细胞外基质(ECM)合成。方法:实时荧光定量PCR(qRT-PCR)检测KCNK15-AS1和miR-140-5p在OA软骨组织中的表达。在OA软骨细胞中转染si-KCNK15-AS1,噻唑蓝(MTT)和流式细胞术分别检测细胞增殖与凋亡,蛋白质印迹法(WB)检测细胞周期蛋白D1(Cyclin D1)、p21、Bcl-2相关X蛋白(Bax)、B细胞淋巴瘤/白血病-2(Bcl-2)、白细胞介素-6(IL-6)、IL-8、肿瘤坏死因子-α(TNF-α)、蛋白聚糖(Aggrecan)、Ⅱ型胶原(Collagen typeⅡ)、基质金属蛋白酶-3(MMP-3)、MMP-9、MMP-13的表达。双荧光素酶活性检测分析KCNK15-AS1与miR-140-5p的靶向关系。si-KCNK15-AS1和anti-miR-140-5p共转染,观察干扰miR-140-5p表达对抑制KCNK15-AS1表达诱导的OA软骨细胞增殖、凋亡,炎症因子表达及ECM合成的影响。结果:与正常软骨组织比较,OA软骨组织中KCNK15-AS1表达量明显增加(P<0.05),miR-140-5p表达量显著减少(P<0.05)。抑制KCNK15-AS1表达明显提高OA软骨细胞24 h、48 h、72 h的吸光度(OD)值和CyclinD1、Bcl-2蛋白表达量、Aggrecan、Collagen typeⅡ水平(P<0.05),显著降低细胞凋亡率、p21、Bax蛋白水平、IL-6、TNF-α、IL-8、MMP-3、MMP-9、MMP-13水平(P<0.05)。KCNK15-AS1靶向miR-140-5p抑制miR-140-5p的表达。干扰miR-140-5p表达逆转了抑制KCNK15-AS1表达对OA软骨细胞增殖、ECM合成的促进作用,对细胞凋亡、炎症因子表达的抑制作用。结论:LncRNA KCNK15-AS1通过靶向调控miR-140-5p表达影响OA软骨细胞增殖、凋亡、炎症因子表达及ECM合成。

关键词：长链非编码RNA KCNK15-AS1 微RNA-140-5p 软骨细胞增殖炎症细胞外基质

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基于第四次全国中药资源普查的中国中药资源种类研究

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中国中药杂志 2024年第13期49卷 3409-3413页

作者：黄璐琦郭兰萍张小波余丽莹孙嘉惠中国中医科学院北京100700 中国中医科学院中药资源中心道地药材品质保障与资源持续利用全国重点实验室北京100700 广西壮族自治区药用植物园广西中药资源普查与研究重点实验室广西南宁530023

文章概述了第四次全国中药资源普查关于我国中药资源种类的构成及特点。第四次全国中药资源普查在野外调查和内业整理的基础上,遵循“四有原则”,即有调查记录、有凭证标本、有实物照片、有药用依据,进行中药资源种类的汇总,确保结果的... 详细信息

文章概述了第四次全国中药资源普查关于我国中药资源种类的构成及特点。第四次全国中药资源普查在野外调查和内业整理的基础上,遵循“四有原则”,即有调查记录、有凭证标本、有实物照片、有药用依据,进行中药资源种类的汇总,确保结果的科学性和准确性。根据汇总结果,我国中药资源有18817种,包括药用植物15321种、药用菌物826种、药用动物2517种、药用矿物153种。此外,第四次全国中药资源普查还分专题调查了中国特有药用植物3151种,濒危药用植物资源464种,发现新物种196种。这些最新的中药资源种类统计结果,将为中药资源保护管理和开发利用提供最新的基础数据,为中医药事业的发展提供科学指导。

关键词：中药资源普查种类特征药用植物药用菌物药用动物药用矿物

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The Development of a Venus Flytrap Inspired Soft Robot Driven by IPMC

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Journal of Bionic Engineering 2023年第1期20卷 406-415页

作者： Jiahua Li Aifen Tian Yue sun bin Feng Hongyan Wang Xinrong Zhang School of Materials Science and Engineering Xi’an University of Science and TechnologyXi’an710054China School of Mechanical Engineering Xi’an University of Science and TechnologyXi’an710054China Shaanxi Science and Technology Holding Group Shaanxi Kekong Technology Industry Research Institute Co.LtdXi’an710000China The Key Laboratory of Road Construction Technology and Equipment MOE Chang’an UniversityXi’an710064China

In recent years,more and more creatures in nature have become the source of inspiration for people to study bionic soft *** such robots appear in the public’s *** this paper,a Venus flytrap robot similar to the biological Venus flytrap in appearance was designed and *** was mainly cast by Polydimethylsiloxane(PDMs)and driven by the flexible material of Ionic Polymer Metal Composites(IPMCs).Combining with ANSYS and related experiments,the appropriate voltage and the size of IPMC were *** results showed that the performance of the Venus flytrap robot was the closest to the biological Venus flytrap when the size of IPMC length,width and driving voltage reach to 3 cm,1 cm and 5.5 V,***,the closing speed and angle reached 8.22°/s and 37°,***,the fly traps also could be opened and closed repeatedly and captured a small ball with a mass of 0.3 g firmly in its middle and tip.

关键词： Bioinspired soft robot.Venus flytrap ANSYS Ionic polymer metal composite

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Tolerance analysis of multiple-element linear retrodirective cross-eye jamming

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Journal of Systems Engineering and Electronics 2020年第3期31卷 460-469页

作者： LIU Tianpeng WEI Xizhang PENG Bo LIU Zhen sun bin GUAN Zhiqiang College of Electronic Science and Technology National University of Defense TechnologyChangsha 410073China School of Electronic and Communication Engineering Sun Yat-sen UniversityShenzhen 518107China Beijing Institute of Tracking and Telecommunication Technology Beijing 100094China Beijing Huahang Radio Measurement Institute Beijing 100013China

Tolerance sensitivity limits the practical application of the cross-eye *** literature has demonstrated that retrodirective cross-eye jamming with multiple antenna elements possesses the advantage of loose tolerance requirements compared to traditional cross-eye ***,the previous analysis was limited,because there are still some factors affecting the parameter tolerance of the multiple-element retrodirective cross-eye jamming(MRCJ)system and they have not been investigated completely,such as the loop difference,the baseline ratio and the jammer-to-signal *** paper performs a comprehensive tolerance analysis of the MRCJ system with a nonuniformspacing linear *** results demonstrate the tolerance effects of the above influence factors and give reasonable advice for easing tolerance sensitivity.

关键词： electronic warfare(EW) electronic countermeasure(ECM) cross-eye jamming radar active jamming tolerance

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Detection of skin defects on loquat using hyperspectral imaging combining both band radio and improved three-phase level set segmentation method

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Food Quality and Safety 2023年第1期7卷 100-111页

作者： Zhaoyang Han bin Li Qiu Wang Zhaoxiang sun Yande Liu School of Mechatronics&Vehicle Engineering East China Jiaotong UniversityNational and Local Joint Engineering Research Center of Fruit Intelligent Photoelectric Detection Technology and EquipmentNanchangChina

Background and objectives Skin defects are one of the primary problems that occur in post-harvest grading and processing of *** defects lead to the loquat being easily destroyed during transportation and storage,which causes the risk of other loquats being infected,affecting the selling *** and Methods In this paper,a method combining band radio image with an improved three-phase level set segmentation algorithm(ITPLSSM)is proposed to achieve high accuracy,rapid,and non-destructive detection of skin defects of *** component analysis(PCA)was used to find the characteristic wavelength and PC images to distinguish four types of skin *** best band ratio image based on characteristic wavelength was *** The band ratio image(Q782/944)based on PC2 image is the best segmented *** on pseudo-color image enhancement,morphological processing,and local clustering criteria,the band ratio image(Q782/944)has better contrast between defective and normal areas in ***,the ITPLSSM was used to segment the processing band ratio image(Q782/944),with an accuracy of 95.28%.Conclusions The proposed ITPLSSM method is effective in distinguishing four types of skin ***,it also effectively segments images with intensity inhomogeneities.

关键词： Loquat skin defects hyperspectral imaging multispectral images band ratio improved three-phase level set segmentation.

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Two aquaporins,PIP1;1 and PIP2;1,mediate the uptake of neonicotinoid pesticides in plants

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Plant Communications 2024年第5期5卷 176-188页

作者： Qun Wan Yixin Li Jinjin Cheng Ya Wang Jing Ge Tingli Liu Liya Ma Yong Li Jianan Liu Chunli Zhou Haocong Li Xing sun Xiaolong Chen Qing X.Li Xiangyang Yu Key Laboratory of Food Quality and Safety of Jiangsu Province State Key Laboratory Breeding BaseNanjing 210014China Institute of Food Safety and Nutrition Jiangsu Academy of Agricultural Sciences50 Zhongling StreetNanjing 210014China Jiangsu Provincial Key Construction Laboratory of Special Biomass Resource Utilization Nanjing Xiaozhuang University3601 Hongjin AvenueNanjing 211171China Department of Molecular Biosciences and Bioengineering University of Hawaii at ManoaHonoluluHI 96822USA

Neonicotinoids(NEOs),a large class of organic compounds,are a type of commonly used pesticide for crop *** uptake and accumulation in plants are prerequisites for their intra-and intercellular move-ments,transformation,and *** the molecular mechanisms that underpin NEO uptake by plants is crucial for effective application,which remains ***,we demonstrate that NEOs enter plant cells primarily through the transmembrane symplastic pathway and accumulate mainly in the *** plasma membrane intrinsic proteins discovered in Brassica rapa,BraPIP1;1 and BraPIP2;1,were found to encode aquaporins(AQPs)that are highly permeable to NEOs in different plant species and facilitate NEO subcellular diffusion and *** conserved transport function was further demonstrated in Xenopus laevis oocyte and yeast ***1;1 and BraPIP2;1 gene knockouts and interaction as-says suggested that their proteins can form functional *** of the potential of mean force indicated a negative correlation between NEO uptake and the energy barrier of BraPIP1;1 *** study shows that AQPs transport organic compounds with greater osmolarity than previously thought,providing new insight into the molecular mechanisms of organic compound uptake and facilitating innovations in systemic pesticides.

关键词： neonicotinoid aquaporin Brassica rapa plasma membrane uptake systemic pesticide

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Cytological and transcriptional analysis reveal phosphatidylinositol signaling pathway plays key role in mitotic division of Pyropia yezoensis

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Journal of Oceanology and Limnology 2022年第3期40卷 1148-1159页

作者： Yunke ZHU Xinran WANG bin sun Xianghai TANG Yunxiang MAO Key Laboratory of Marine Genetics and Breeding(Ministry of Education) College of Marine Life SciencesOcean University of ChinaQingdao 266003China MOE Key Laboratory of Utilization and Conservation for Tropical Marine Bioresources College of Fisheries and Life ScienceHainan Tropical Ocean UniversitySanya 572022China Laboratory for Marine Biology and Biotechnology Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China

The phosphatidylinositol(PI)signaling system,a central regulator of eukaryotic metabolism,is widely found in eukaryotes for regulating a variety of cell *** of the genes in the PI signaling system were found conserved in Pyropia *** this experiment,wortmannin was used as an inhibitor to inhibit the activity of phosphatidylinositol-3 kinase(PI3K),an important regulator of the PI signaling *** wortmannin treatment,the mitotic division of *** was signifi cantly inhibited in a dose-dependent manner,and the mitotic division percentage was reduced by 68.1%and 91.9%in the 5-and 10-μmol/L groups,*** thalli were treated with wortmannin,the levels of reactive oxygen species(ROS)were signifi cantly ***,the expression level of PI3K was inhibited and the expression levels of downstream genes regulated by PI3K was signifi cantly *** the PI3K-AGC signaling pathway,the expression levels of Serine/threonine protein kinase(AGC)and cyclindependent kinases A(CDKA)were downregulated,while WEE1 kinase gene(WEE1)was *** nicotinamide adenine dinucleotide phosphate(NADPH)oxidase genes were downregulated after wortmannin *** results indicate that the PI signaling system plays an important role in the regulation of cell activity in *** was speculated that the growth and development of *** might be regulated by *** PI3K,which promoted the expression of the AGC gene and further regulates the expression of downstream WEE1 and CDKA genes to advance mitotic division,and also promoted the expression level of NADPH oxidase that regulates ROS homeostasis.

关键词： Pyropia yezoensis phosphatidylinositol signaling system reactive oxygen species mitotic division

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Fast BSC-based algorithm for near-field signal localization via uniform circular array

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Journal of Systems Engineering and Electronics 2022年第2期33卷 269-278页

作者： SU Xiaolong LIU Zhen sun bin WANG Yang CHEN Xin LI Xiang College of Electronic Science and Technology National University of Defense TechnologyChangsha 410073China Beijing Institute of Tracking and Telecommunication Technology Beijing 100094China

In this paper,we propose a beam space coversion(BSC)-based approach to achieve a single near-field signal local-ization under uniform circular array(UCA).By employing the centro-symmetric geometry of UCA,we apply BSC to extract the two-dimensional(2-D)angles of near-field signal in the Van-dermonde form,which allows for azimuth and elevation angle estimation by utilizing the improved estimation of signal para-meters via rotational invariance techniques(ESPRIT)*** substituting the calculated 2-D angles into the direction vec-tor of near-field signal,the range parameter can be conse-quently obtained by the 1-D multiple signal classification(MU-SIC)*** demonstrate that the proposed al-gorithm can achieve a single near-field signal localization,which can provide satisfactory performance and reduce computational complexity.

关键词： near-field signal uniform circular array(UCA) beam space conversion(BSC) improved estimation of signal parame-ters via rotational invariance techniques(ESPRIT) 1-D multiple signal classification(MUSIC) parameter estimation

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Enhanced Ionic Accessibility of Flexible MXene Electrodes Produced by Natural Sedimentation

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Nano-Micro Letters 2020年第7期12卷 145-155页

作者： Ning sun Zhaoruxin Guan Qizhen Zhu Babak Anasori Yury Gogotsi bin Xu State Key Laboratory of Organic-Inorganic Composites Beijing Key Laboratory of Electrochemical Process and Technology for MaterialsBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China Department of Materials Science and Engineering and A.J.Drexel Nanomaterials Institute Drexel UniversityPhiladelphiaPA 19104USA Department of Mechanical and Energy Engineering Integrated Nanosystems Development InstitutePurdue School of Engineering and TechnologyIndiana University-Purdue University IndianapolisIndianapolisIN 46202USA

MXene nanosheets have been used for preparing highly flexible integrated electrodes due to their two-dimensional(2D)morphology,flexibility,high conductivity,and abundant functional ***,restacking of 2D nanosheets inhibits the ion transport in MXene electrodes,limiting their thickness,rate performance,and energy storage ***,we employed a natural sedimentation method instead of the conventional vacuum-assisted filtration to prepare flexible Ti3C2TxMXene films with enlarged interlayer spacing,which facilitates the access of the lithium ions to the interlayers and thus leads to a greatly enhanced electrochemical *** naturally sedimented flexible film shows a double lithium storage capacity compared to the conventional vacuum-filtered MXene film,along with improved rate performance and excellent cycle stability.

关键词： MXene Natural sedimentation Vacuum filtration Interlayer spacing Li-storage

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